JPS5626194A - Purification of long-chain dicarboxylic acid produced by fermentation - Google Patents
Purification of long-chain dicarboxylic acid produced by fermentationInfo
- Publication number
- JPS5626194A JPS5626194A JP10162379A JP10162379A JPS5626194A JP S5626194 A JPS5626194 A JP S5626194A JP 10162379 A JP10162379 A JP 10162379A JP 10162379 A JP10162379 A JP 10162379A JP S5626194 A JPS5626194 A JP S5626194A
- Authority
- JP
- Japan
- Prior art keywords
- dicarboxylic acid
- long
- chain dicarboxylic
- filtrate
- chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
PURPOSE: To obtain a high-purity long-chain dicarboxylic acid, by dissolving a long chain dicarboxylic acid separated from a fermentation broth in an aqueous alkali, adding activated clay to the aqueous solution, filtering the broth under pressure, and acidifying the filtrate to separate the long-chain dicarboxylic acid.
CONSTITUTION: A microorganism capable of producing a dicarboxylic acid is incubated in a culture medium of a 10W18C straight chain hydrocarbon, e.g. n tridecane, as a substrate to give a fermentation broth, which is filtered through diatomaceous earth under pressure. The filtrate and the cake washing are mixed to separate and deposit the formed long-chain dicarboxylic acid. The separated and deposited dicarboxylic acid is dissolved in an aqueous solution of NaOH etc., and adjusted to pH about 11. Activated clay or acid clay is added to the solution, and the solution is filtered under pressure with agitation. The filtrate is then adjusted to pH≤4 to deposit the objective dicarboxylic acid of purity ≥97% with slight coloration. The dicarboxylic acid is further dissolved in an alkaline aqueous solution, and the same operations are repeated to give a white product of higher purity (99%).
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10162379A JPS5626194A (en) | 1979-08-09 | 1979-08-09 | Purification of long-chain dicarboxylic acid produced by fermentation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10162379A JPS5626194A (en) | 1979-08-09 | 1979-08-09 | Purification of long-chain dicarboxylic acid produced by fermentation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5626194A true JPS5626194A (en) | 1981-03-13 |
JPS5755400B2 JPS5755400B2 (en) | 1982-11-24 |
Family
ID=14305520
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10162379A Granted JPS5626194A (en) | 1979-08-09 | 1979-08-09 | Purification of long-chain dicarboxylic acid produced by fermentation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5626194A (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6218574B1 (en) | 1998-12-03 | 2001-04-17 | China Petrochemical Corporation | Process for purifying long-chain dicarboxylic acid |
CN1064951C (en) * | 1997-12-08 | 2001-04-25 | 中国石油化工总公司抚顺石油化工研究院 | Method for refining long-chain bibasic acid |
CN1088055C (en) * | 1999-09-29 | 2002-07-24 | 中国石油化工集团公司 | Process for extracting alpha-or omege-alkadicarboxylic acid from fermented liquid and refining it |
DE102012105128A1 (en) | 2011-09-30 | 2013-04-04 | Institute Of Microbiology Chinese Academy Of Sciences | Cleaning or processing of long chain dicarboxylic acid or its salt, comprises e.g. acidifying raw material, dissolving, decolorizing, filtering, drying, suspending in water, lowering temperature and obtaining dicarboxylic acid crystals |
CN104496791A (en) * | 2014-12-26 | 2015-04-08 | 淄博广通化工有限责任公司 | Method for purifying and refining brassylic acid |
-
1979
- 1979-08-09 JP JP10162379A patent/JPS5626194A/en active Granted
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1064951C (en) * | 1997-12-08 | 2001-04-25 | 中国石油化工总公司抚顺石油化工研究院 | Method for refining long-chain bibasic acid |
US6218574B1 (en) | 1998-12-03 | 2001-04-17 | China Petrochemical Corporation | Process for purifying long-chain dicarboxylic acid |
CN1079389C (en) * | 1998-12-03 | 2002-02-20 | 中国石油化工集团公司 | Process for refining long-chain biatomic acid |
CN1088055C (en) * | 1999-09-29 | 2002-07-24 | 中国石油化工集团公司 | Process for extracting alpha-or omege-alkadicarboxylic acid from fermented liquid and refining it |
DE102012105128A1 (en) | 2011-09-30 | 2013-04-04 | Institute Of Microbiology Chinese Academy Of Sciences | Cleaning or processing of long chain dicarboxylic acid or its salt, comprises e.g. acidifying raw material, dissolving, decolorizing, filtering, drying, suspending in water, lowering temperature and obtaining dicarboxylic acid crystals |
DE102012105128B4 (en) | 2011-09-30 | 2023-05-17 | Institute Of Microbiology, Chinese Academy Of Sciences | Process for preparing long-chain dicarboxylic acids |
CN104496791A (en) * | 2014-12-26 | 2015-04-08 | 淄博广通化工有限责任公司 | Method for purifying and refining brassylic acid |
Also Published As
Publication number | Publication date |
---|---|
JPS5755400B2 (en) | 1982-11-24 |
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