JPS5618992A - Beta-carboxyethylsilicon (germanium) sesquioxide and its preparation - Google Patents
Beta-carboxyethylsilicon (germanium) sesquioxide and its preparationInfo
- Publication number
- JPS5618992A JPS5618992A JP9402979A JP9402979A JPS5618992A JP S5618992 A JPS5618992 A JP S5618992A JP 9402979 A JP9402979 A JP 9402979A JP 9402979 A JP9402979 A JP 9402979A JP S5618992 A JPS5618992 A JP S5618992A
- Authority
- JP
- Japan
- Prior art keywords
- sesquioxide
- formula
- carboxyethylsilicon
- germanium
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- CCBBNHUIFSFXFO-UHFFFAOYSA-N [Ge].C(=O)(O)CC[Si] Chemical compound [Ge].C(=O)(O)CC[Si] CCBBNHUIFSFXFO-UHFFFAOYSA-N 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000003301 hydrolyzing effect Effects 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- IQULGZQMMPRBLA-UHFFFAOYSA-N 2-carboxyethylgermanium Chemical compound OC(=O)CC[Ge] IQULGZQMMPRBLA-UHFFFAOYSA-N 0.000 abstract 1
- VXZCIDLVEYVOOX-UHFFFAOYSA-N 3-trichlorogermylpropanenitrile Chemical compound Cl[Ge](Cl)(Cl)CCC#N VXZCIDLVEYVOOX-UHFFFAOYSA-N 0.000 abstract 1
- NLIJOIUVZBYQRS-UHFFFAOYSA-N 3-trichlorogermylpropanoic acid Chemical compound OC(=O)CC[Ge](Cl)(Cl)Cl NLIJOIUVZBYQRS-UHFFFAOYSA-N 0.000 abstract 1
- OLBGECWYBGXCNV-UHFFFAOYSA-N 3-trichlorosilylpropanenitrile Chemical compound Cl[Si](Cl)(Cl)CCC#N OLBGECWYBGXCNV-UHFFFAOYSA-N 0.000 abstract 1
- IFCUJUFSWQVNIH-UHFFFAOYSA-N 3-trichlorosilylpropanoic acid Chemical compound OC(=O)CC[Si](Cl)(Cl)Cl IFCUJUFSWQVNIH-UHFFFAOYSA-N 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 230000003327 cancerostatic effect Effects 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
NEW MATERIAL:A β-carboxyethylsilicon (germanium) sesquioxide of formula I (x is 0.05W1.00).
EXAMPLE: The compound of formula II.
USE: Carcinostatic agent and remedy for hypertension. The storage stability and thermal stability of the compound are higher than those of β-carboxyethylgermanium sesquioxide of formula III.
PROCESS: The compound of formula I is prepared, e.g. by hydrolyzing a mixture of β-cyanoethyltrichlorosilane and β-cyanoethyltrichlorogermane, if necessary in the presence of a basic catalyst, or by mixing β-carboxyethyltrichlorosilane and β- carboxyethyltrichlorogermane in an organic solvent, and hydrolyzing the mixture.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP54094029A JPS6023676B2 (en) | 1979-07-24 | 1979-07-24 | β-carboxyethyl silicon (germanium) sesquioxide and its manufacturing method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP54094029A JPS6023676B2 (en) | 1979-07-24 | 1979-07-24 | β-carboxyethyl silicon (germanium) sesquioxide and its manufacturing method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5618992A true JPS5618992A (en) | 1981-02-23 |
| JPS6023676B2 JPS6023676B2 (en) | 1985-06-08 |
Family
ID=14099130
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP54094029A Expired JPS6023676B2 (en) | 1979-07-24 | 1979-07-24 | β-carboxyethyl silicon (germanium) sesquioxide and its manufacturing method |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6023676B2 (en) |
-
1979
- 1979-07-24 JP JP54094029A patent/JPS6023676B2/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6023676B2 (en) | 1985-06-08 |
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