JPS56169653A - Preparation of 7- 3-isopropylamino-2-hydroxypropoxy indene - Google Patents
Preparation of 7- 3-isopropylamino-2-hydroxypropoxy indeneInfo
- Publication number
- JPS56169653A JPS56169653A JP7300380A JP7300380A JPS56169653A JP S56169653 A JPS56169653 A JP S56169653A JP 7300380 A JP7300380 A JP 7300380A JP 7300380 A JP7300380 A JP 7300380A JP S56169653 A JPS56169653 A JP S56169653A
- Authority
- JP
- Japan
- Prior art keywords
- indene
- formula
- yloxymethyl
- oxazolidinone
- hydroxypropoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: To obtain the titled compound useful for angina pectoris, arrhythmia, etc. in high yield and purity in a short time, by hydrolyzing 3-isopropyl-5-(indene-7- yloxymethyl)-2-oxazolidinone.
CONSTITUTION: 3-Isopropyl-5- ( indene-7-yloxymethyl) -2-oxazolidinone of formula I is hydrolyzed in the presence of a base, e.g. sodium hydroxyide or potassium hydroxide, in a solvent, e.g. methanol or ethanol, to give the aimed substance of formula II readily. The starting compound of formula I is obtained readily by condensing 7-(2,3-epoxypropoxy)indene of formula III with ethyl isopropylcarbamate of formula IV in the presence of a tertiary amine.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7300380A JPS56169653A (en) | 1980-05-31 | 1980-05-31 | Preparation of 7- 3-isopropylamino-2-hydroxypropoxy indene |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7300380A JPS56169653A (en) | 1980-05-31 | 1980-05-31 | Preparation of 7- 3-isopropylamino-2-hydroxypropoxy indene |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS56169653A true JPS56169653A (en) | 1981-12-26 |
Family
ID=13505737
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP7300380A Pending JPS56169653A (en) | 1980-05-31 | 1980-05-31 | Preparation of 7- 3-isopropylamino-2-hydroxypropoxy indene |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56169653A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2011102325A (en) * | 2006-08-08 | 2011-05-26 | Mpr Services Inc | Method for improving conversion from oxazolidone to alkanolamine |
-
1980
- 1980-05-31 JP JP7300380A patent/JPS56169653A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2011102325A (en) * | 2006-08-08 | 2011-05-26 | Mpr Services Inc | Method for improving conversion from oxazolidone to alkanolamine |
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