JPS56169653A - Preparation of 7- 3-isopropylamino-2-hydroxypropoxy indene - Google Patents

Preparation of 7- 3-isopropylamino-2-hydroxypropoxy indene

Info

Publication number
JPS56169653A
JPS56169653A JP7300380A JP7300380A JPS56169653A JP S56169653 A JPS56169653 A JP S56169653A JP 7300380 A JP7300380 A JP 7300380A JP 7300380 A JP7300380 A JP 7300380A JP S56169653 A JPS56169653 A JP S56169653A
Authority
JP
Japan
Prior art keywords
indene
formula
yloxymethyl
oxazolidinone
hydroxypropoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP7300380A
Other languages
Japanese (ja)
Inventor
Kazuo Satoie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TOHO IYAKU KENKYUSHO KK
Original Assignee
TOHO IYAKU KENKYUSHO KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TOHO IYAKU KENKYUSHO KK filed Critical TOHO IYAKU KENKYUSHO KK
Priority to JP7300380A priority Critical patent/JPS56169653A/en
Publication of JPS56169653A publication Critical patent/JPS56169653A/en
Pending legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: To obtain the titled compound useful for angina pectoris, arrhythmia, etc. in high yield and purity in a short time, by hydrolyzing 3-isopropyl-5-(indene-7- yloxymethyl)-2-oxazolidinone.
CONSTITUTION: 3-Isopropyl-5- ( indene-7-yloxymethyl) -2-oxazolidinone of formula I is hydrolyzed in the presence of a base, e.g. sodium hydroxyide or potassium hydroxide, in a solvent, e.g. methanol or ethanol, to give the aimed substance of formula II readily. The starting compound of formula I is obtained readily by condensing 7-(2,3-epoxypropoxy)indene of formula III with ethyl isopropylcarbamate of formula IV in the presence of a tertiary amine.
COPYRIGHT: (C)1981,JPO&Japio
JP7300380A 1980-05-31 1980-05-31 Preparation of 7- 3-isopropylamino-2-hydroxypropoxy indene Pending JPS56169653A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP7300380A JPS56169653A (en) 1980-05-31 1980-05-31 Preparation of 7- 3-isopropylamino-2-hydroxypropoxy indene

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7300380A JPS56169653A (en) 1980-05-31 1980-05-31 Preparation of 7- 3-isopropylamino-2-hydroxypropoxy indene

Publications (1)

Publication Number Publication Date
JPS56169653A true JPS56169653A (en) 1981-12-26

Family

ID=13505737

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7300380A Pending JPS56169653A (en) 1980-05-31 1980-05-31 Preparation of 7- 3-isopropylamino-2-hydroxypropoxy indene

Country Status (1)

Country Link
JP (1) JPS56169653A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011102325A (en) * 2006-08-08 2011-05-26 Mpr Services Inc Method for improving conversion from oxazolidone to alkanolamine

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011102325A (en) * 2006-08-08 2011-05-26 Mpr Services Inc Method for improving conversion from oxazolidone to alkanolamine

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