JPS56154418A - Making method of polymer composition containing erythrocyte - Google Patents

Making method of polymer composition containing erythrocyte

Info

Publication number
JPS56154418A
JPS56154418A JP5632180A JP5632180A JPS56154418A JP S56154418 A JPS56154418 A JP S56154418A JP 5632180 A JP5632180 A JP 5632180A JP 5632180 A JP5632180 A JP 5632180A JP S56154418 A JPS56154418 A JP S56154418A
Authority
JP
Japan
Prior art keywords
erythrocytes
carbon monoxide
type
polymerization
composition containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP5632180A
Other languages
Japanese (ja)
Other versions
JPS636047B2 (en
Inventor
Isao Kaetsu
Fumio Yoshii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Japan Atomic Energy Agency
Original Assignee
Japan Atomic Energy Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Atomic Energy Research Institute filed Critical Japan Atomic Energy Research Institute
Priority to JP5632180A priority Critical patent/JPS56154418A/en
Publication of JPS56154418A publication Critical patent/JPS56154418A/en
Publication of JPS636047B2 publication Critical patent/JPS636047B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

Abstract

PURPOSE: Carbon monoxide type erythrocytes are mixed with a polymerizable monomer solution and the polymerization is effected to produce the titled composition stabilized from hemolyzation.
CONSTITUTION: Carbon monoxide type erythrocytes are mixed with at least one of vinyl polymerizable monomers such as methoxypolyethylene glycol methacrylate containing an organic compound bearing one or more aldehyde groups in one molecule such as glutaraldehyde. Then, the mixture is irradiated with ionizing radiation, preferably dose is less than 0.1 Mrad and solidified by polymerization, thus giving the polymerizable composition containing erythrocytes. Erythrocytes are labile to hemolyzation, however, when they are converted to carbon monoxide type which has polymerization inhibition activity and contains no oxygen and included in the polymer, they can be stored as an immobilized product for a long time. When an oxygen gas is passed through the immobilized carbon monoxide type erythrocytes under irradiation with white light, the erythrocytes are readily converted to the natural type.
COPYRIGHT: (C)1981,JPO&Japio
JP5632180A 1980-04-30 1980-04-30 Making method of polymer composition containing erythrocyte Granted JPS56154418A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP5632180A JPS56154418A (en) 1980-04-30 1980-04-30 Making method of polymer composition containing erythrocyte

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5632180A JPS56154418A (en) 1980-04-30 1980-04-30 Making method of polymer composition containing erythrocyte

Publications (2)

Publication Number Publication Date
JPS56154418A true JPS56154418A (en) 1981-11-30
JPS636047B2 JPS636047B2 (en) 1988-02-08

Family

ID=13023898

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5632180A Granted JPS56154418A (en) 1980-04-30 1980-04-30 Making method of polymer composition containing erythrocyte

Country Status (1)

Country Link
JP (1) JPS56154418A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5476764A (en) * 1994-09-16 1995-12-19 The Regents Of The University Of California Method using CO for extending the useful shelf-life of refrigerated red blood cells
JP2021518564A (en) * 2018-03-16 2021-08-02 クライオカプセル Biological sample embedding fluid for imaging biological samples with optical and / or electron microscopy

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5476764A (en) * 1994-09-16 1995-12-19 The Regents Of The University Of California Method using CO for extending the useful shelf-life of refrigerated red blood cells
JP2021518564A (en) * 2018-03-16 2021-08-02 クライオカプセル Biological sample embedding fluid for imaging biological samples with optical and / or electron microscopy

Also Published As

Publication number Publication date
JPS636047B2 (en) 1988-02-08

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