JPS56138156A - Preparation of s,s'-biscyclotetrapeptide and its preparation - Google Patents
Preparation of s,s'-biscyclotetrapeptide and its preparationInfo
- Publication number
- JPS56138156A JPS56138156A JP4095780A JP4095780A JPS56138156A JP S56138156 A JPS56138156 A JP S56138156A JP 4095780 A JP4095780 A JP 4095780A JP 4095780 A JP4095780 A JP 4095780A JP S56138156 A JPS56138156 A JP S56138156A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- sulfhydryl
- ion
- tetrapeptide
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Peptides Or Proteins (AREA)
Abstract
NEW MATERIAL:An S,S'-biscyclotetrapeptide shown by the formula I (R is H or methyl).
EXAMPLE: Cyclo-(glycyl-S-p-methoxybenzyl-L-cystyl-sarcosil-L-prolyl).
USE: An ion including agent. Although it has 8 structural amino acids, it is linked with an alkali metal ion and an alkaline earth metal ion to form a conjugated compound, which is widely used in fields of analysis, drugs, and agricultural chemicals as an ion sensor.
PROCESS: A tetrapeptide shown by the formula II (R' is active ester; R" is sulfhydryl- protecting group) is subjected to ring formation, the sulfhydryl-protecting group R" is removed, and the resulting compound is dimerized, to give a compound shown by the formula I. A tetrapeptide active ester with its sulfhydryl group protected is preferably used in the form of an acid salt (e.g., hydrochloride, etc.).
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55040957A JPS5842863B2 (en) | 1980-03-29 | 1980-03-29 | S,S'-biscyclotetrapeptide and method for producing the same |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP55040957A JPS5842863B2 (en) | 1980-03-29 | 1980-03-29 | S,S'-biscyclotetrapeptide and method for producing the same |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS56138156A true JPS56138156A (en) | 1981-10-28 |
JPS5842863B2 JPS5842863B2 (en) | 1983-09-22 |
Family
ID=12594963
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP55040957A Expired JPS5842863B2 (en) | 1980-03-29 | 1980-03-29 | S,S'-biscyclotetrapeptide and method for producing the same |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5842863B2 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60172094A (en) * | 1984-02-17 | 1985-09-05 | 株式会社大真空 | Display information exchanger for electrostatic type display unit |
JPS60172093A (en) * | 1984-02-17 | 1985-09-05 | 株式会社大真空 | Display information exchanger for electrostatic type display unit |
-
1980
- 1980-03-29 JP JP55040957A patent/JPS5842863B2/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
JPS5842863B2 (en) | 1983-09-22 |
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