JPS56137140A - Optical measuring method of blood coagulation - Google Patents

Optical measuring method of blood coagulation

Info

Publication number
JPS56137140A
JPS56137140A JP3955780A JP3955780A JPS56137140A JP S56137140 A JPS56137140 A JP S56137140A JP 3955780 A JP3955780 A JP 3955780A JP 3955780 A JP3955780 A JP 3955780A JP S56137140 A JPS56137140 A JP S56137140A
Authority
JP
Japan
Prior art keywords
intensity
laser light
photoscattering
cubet
blood coagulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP3955780A
Other languages
Japanese (ja)
Other versions
JPH0223825B2 (en
Inventor
Yoshinobu Miyashita
Tadashi Hamanaka
Haruki Oishi
Taido Ueno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujifilm Wako Pure Chemical Corp
Original Assignee
Wako Pure Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wako Pure Chemical Industries Ltd filed Critical Wako Pure Chemical Industries Ltd
Priority to JP3955780A priority Critical patent/JPS56137140A/en
Publication of JPS56137140A publication Critical patent/JPS56137140A/en
Publication of JPH0223825B2 publication Critical patent/JPH0223825B2/ja
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

PURPOSE:To measure the photoscattering intensity exclusively caused by fibrin separation selectively and quickly with high sensitivity, even for the body to be inspected with high turbidity, by radiating laser light to the fibrin separated in the liquid to be tested with blood coagulation and detecting the change in the intensity of photoscattering with a given angle. CONSTITUTION:In the inspection of abnormal blood coagulation such as hemophilia, a given amount of laser light flux is radiated in the reaction cubet 2 in which the mixed liquid 4 with reagnent and blood or blood plasma to be inspected is put, from the laser light source (helium neon laser in 632.8nm) 1. The measurement is done for the intensity of light scattering from the cubet 2 in the range of angle theta of 30-60 deg. between the laser light axis through the center of the cubet 2 and the photodetector 3, and the output converted into an electric signal is operated with the amplifier 5, A/D converter 6 and computer 7 to discriminate the coagulation time point and to display the data on the printer 8. Thus, the change in the photoscattering intensity only is selectively detected independently of the turbidity due to other causes, allowing quick and accurate automatic measurement.
JP3955780A 1980-03-27 1980-03-27 Optical measuring method of blood coagulation Granted JPS56137140A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP3955780A JPS56137140A (en) 1980-03-27 1980-03-27 Optical measuring method of blood coagulation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3955780A JPS56137140A (en) 1980-03-27 1980-03-27 Optical measuring method of blood coagulation

Publications (2)

Publication Number Publication Date
JPS56137140A true JPS56137140A (en) 1981-10-26
JPH0223825B2 JPH0223825B2 (en) 1990-05-25

Family

ID=12556364

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3955780A Granted JPS56137140A (en) 1980-03-27 1980-03-27 Optical measuring method of blood coagulation

Country Status (1)

Country Link
JP (1) JPS56137140A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0091636A2 (en) * 1982-04-04 1983-10-19 Wako Pure Chemical Industries, Ltd. Method for the photometric determination of biological agglutination
JPS606871A (en) * 1983-06-24 1985-01-14 Ono Pharmaceut Co Ltd Method and device for detecting blood clotting point
US6766187B1 (en) * 2000-09-18 2004-07-20 Lumenis Inc. Method for detecting coagulation in laser treatment of blood vessels

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5014466B2 (en) 2010-06-04 2012-08-29 徹 小幡 Gel particle measuring device

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5057483A (en) * 1973-09-20 1975-05-19
JPS5190883A (en) * 1975-01-29 1976-08-09
JPS5467496A (en) * 1977-11-09 1979-05-30 Itoman Kk Device for measuring solidification of blood plasma
JPS5469497A (en) * 1977-11-12 1979-06-04 Kyoto Daiichi Kagaku Kk Method and device for measuring blood solidification time

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5057483A (en) * 1973-09-20 1975-05-19
JPS5190883A (en) * 1975-01-29 1976-08-09
JPS5467496A (en) * 1977-11-09 1979-05-30 Itoman Kk Device for measuring solidification of blood plasma
JPS5469497A (en) * 1977-11-12 1979-06-04 Kyoto Daiichi Kagaku Kk Method and device for measuring blood solidification time

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0091636A2 (en) * 1982-04-04 1983-10-19 Wako Pure Chemical Industries, Ltd. Method for the photometric determination of biological agglutination
US4766083A (en) * 1982-04-04 1988-08-23 Wako Pure Chemical Industries, Ltd. Method for the photometric determination of biological agglutination
JPS606871A (en) * 1983-06-24 1985-01-14 Ono Pharmaceut Co Ltd Method and device for detecting blood clotting point
JPH0153749B2 (en) * 1983-06-24 1989-11-15 Takashi Yoshikawa
US6766187B1 (en) * 2000-09-18 2004-07-20 Lumenis Inc. Method for detecting coagulation in laser treatment of blood vessels

Also Published As

Publication number Publication date
JPH0223825B2 (en) 1990-05-25

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