JPS56135446A - Preparation of optically active l-alpha-phenyl-beta-(p-tolyl)ethylamine - Google Patents
Preparation of optically active l-alpha-phenyl-beta-(p-tolyl)ethylamineInfo
- Publication number
- JPS56135446A JPS56135446A JP3974980A JP3974980A JPS56135446A JP S56135446 A JPS56135446 A JP S56135446A JP 3974980 A JP3974980 A JP 3974980A JP 3974980 A JP3974980 A JP 3974980A JP S56135446 A JPS56135446 A JP S56135446A
- Authority
- JP
- Japan
- Prior art keywords
- optically active
- tolyl
- phenyl
- ethylamine
- beta
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PURPOSE: To obtain the titled compound useful as an optical resolving agent, etc. at a low cost in high yield, by reacting α-phenyl-β-(p-tolyl)ethylamine containing an excess of the l-isomer with optically active L-(+)-tartaric acid.
CONSTITUTION: α-Phenyl-β-(p-tolyl)ethylamine containing an excess of the l-isomer is reacted with optically active L-(+)-tartaric acid in a molar amount of 0.8W 1.5 times that of the α-phenyl-β-(p-tolyl)ethylamine in an organic solvent to give a diastereoisomeric salt. The reaction mixture is then slowly cooled to deposit the optically active l-form diastereoisomeric salt, which is separated and decomposed by an aqueous solution of an alkali to afford an optically active l-form compound of the formula. The resultant compound of the formula is useful as an intermediate for a medicine or agricultural chemical.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3974980A JPS56135446A (en) | 1980-03-27 | 1980-03-27 | Preparation of optically active l-alpha-phenyl-beta-(p-tolyl)ethylamine |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3974980A JPS56135446A (en) | 1980-03-27 | 1980-03-27 | Preparation of optically active l-alpha-phenyl-beta-(p-tolyl)ethylamine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS56135446A true JPS56135446A (en) | 1981-10-22 |
Family
ID=12561605
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP3974980A Pending JPS56135446A (en) | 1980-03-27 | 1980-03-27 | Preparation of optically active l-alpha-phenyl-beta-(p-tolyl)ethylamine |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS56135446A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103204858A (en) * | 2013-03-20 | 2013-07-17 | 广州科瑞生物技术有限公司 | Novel chirality antianxiety medicine prepared on basis of tartaric acid resolution and composition technique |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4834736A (en) * | 1971-07-22 | 1973-05-22 |
-
1980
- 1980-03-27 JP JP3974980A patent/JPS56135446A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4834736A (en) * | 1971-07-22 | 1973-05-22 |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103204858A (en) * | 2013-03-20 | 2013-07-17 | 广州科瑞生物技术有限公司 | Novel chirality antianxiety medicine prepared on basis of tartaric acid resolution and composition technique |
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