JPS56123999A - Cundurango glycoside, its preparation and antitumor agent comprising it - Google Patents
Cundurango glycoside, its preparation and antitumor agent comprising itInfo
- Publication number
- JPS56123999A JPS56123999A JP2769780A JP2769780A JPS56123999A JP S56123999 A JPS56123999 A JP S56123999A JP 2769780 A JP2769780 A JP 2769780A JP 2769780 A JP2769780 A JP 2769780A JP S56123999 A JPS56123999 A JP S56123999A
- Authority
- JP
- Japan
- Prior art keywords
- cundurango
- glycoside
- formula
- antitumor agent
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A cundurango glycoside shown by the formula I (R is O or group shown by the formula II).
EXAMPLE: A cundurango glycoside Ao.
USE: An antitumor agent. In the case of oral administration, a does is 0.6W6mg/kg/ day (cundurango glycoside Ao), and 10W30mg/kg/day (cundurango glycoside Co).
PROCESS: A condurango extract soluble in lower alcohols and chlorinated hydrocarbons excluding CCl4 and insoluble in aliphatic hydrocarbons, CCl4 or aromatic hydrocarbons is obtained from Marsdenia cundurango Reichenbach fil, preferably its bark, and the extract is subjected to high-speed liquid chromatography and separated, to give a cundurago glycoside shown by the formula I.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (23)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2769780A JPS56123999A (en) | 1980-03-05 | 1980-03-05 | Cundurango glycoside, its preparation and antitumor agent comprising it |
US06/179,001 US4320120A (en) | 1979-10-22 | 1980-08-18 | Extracts of Marsdenia cundurango Reichenbach fil |
PL22636980A PL226369A1 (en) | 1979-08-23 | 1980-08-22 | |
NL8004751A NL8004751A (en) | 1979-08-23 | 1980-08-22 | METHOD FOR PREPARING A MEDICINAL AGAINST CANCER, THE MEDICINE PREPARED AND A PROCESS FOR PREPARING THE ACTIVE SUBSTANCE FROM A PLANT REST. |
GB8027337A GB2060379A (en) | 1979-08-23 | 1980-08-22 | Extracts of Marsdenia cundurango Reichenbach fil |
FR8018419A FR2463620A1 (en) | 1979-08-23 | 1980-08-22 | MARSDENIA CINDURANGO REICHENBACH FIL EXTRACTS, PREPARATION METHODS THEREOF, ANTI-TUMOR AGENTS CONTAINING SAME, AND COMPOSITIONS CONTAINING SAME |
ES494468A ES494468A0 (en) | 1979-08-23 | 1980-08-22 | A PROCEDURE FOR OBTAINING AN EXTRACT FROM MARSDE-NIA CUNDURANGO REICHENBACH FIL. |
SE8005919A SE8005919L (en) | 1979-08-23 | 1980-08-22 | EXTRACT OF MARSDENIA CUNDURANGO REICHENBACH FILE |
CA000358853A CA1144917A (en) | 1979-08-23 | 1980-08-22 | Extracts of marsdenia cundurango reichenbach fil |
DE19803031745 DE3031745A1 (en) | 1979-08-23 | 1980-08-22 | MARSDENIA CUNDURANGO REICHENBACH FIL EXTRACTS, METHOD FOR THE PRODUCTION THEREOF, ANTITUARY AND MEDICINAL PRODUCTS CONTAINING THESE EXTRACTS, AND APPLICATION OF THE EXTRACTS FOR THE TREATMENT OF TUMORS |
IT68313/80A IT1141617B (en) | 1979-08-23 | 1980-08-25 | MARSDENIA EXTRACTS CONDURANGO REICHENBACH SON |
IT8167295A IT1144136B (en) | 1980-03-05 | 1981-03-03 | GLUCOSIDES OF CONDUCT ANTI-CANCER AGENTS INCLUDING THEM AND PROCEDURE FOR THEIR PREPARATION |
BE0/204013A BE887793A (en) | 1980-03-05 | 1981-03-04 | NOVEL CONDURANGO-GLYCOSIDES, ANTI-TUMOR AGENTS COMPRISING SAME, AND PROCESS FOR PREPARING THE SAME |
EP19810900551 EP0054570A4 (en) | 1980-03-05 | 1981-03-05 | Novel condurango glycosides, process for their preparation, antineoplastic agent, and composition containing same. |
AU67800/81A AU6780081A (en) | 1980-03-05 | 1981-03-05 | Novel cundurango glycosides, process for their preparation, antineoplastic agent, and composition containing same |
DE19813137612 DE3137612A1 (en) | 1980-03-05 | 1981-03-05 | NOVEL CUNDURANGO GLYCOSIDES, PROCESS FOR THEIR PREPARATION, ANTINEOPLASTIC AGENT, AND COMPOSITION CONTAINING SAME |
GB8209580A GB2093032B (en) | 1980-03-05 | 1981-03-05 | Novel condurango glycosides process for their preparation antineoplastic agent and composition containing same |
CH7326/81A CH647533A5 (en) | 1980-03-05 | 1981-03-05 | CUNDURANGO-GLYCOSIDE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND TUMOR-FIGHTING AGENTS CONTAINING THESE COMPOUNDS. |
PCT/JP1981/000045 WO1981002577A1 (en) | 1980-03-05 | 1981-03-05 | Novel cundurango glycosides,process for their preparation,antineoplastic agent,and composition containing same |
CA000372389A CA1169852A (en) | 1980-03-05 | 1981-03-05 | Condurango glycoside compounds, antitumor agents comprising them and processes for their preparation |
US06/320,974 US4452786A (en) | 1980-03-05 | 1981-03-05 | Condurango glycoside compounds, processes for their preparation, antitumor agents comprising them and compositions |
NL8120043A NL8120043A (en) | 1980-03-05 | 1981-03-05 | Antitumour condurango glycoside derivs. - prepd. by extracting Marsdenia condurango |
SE8202140A SE8202140L (en) | 1980-03-05 | 1982-04-02 | NEW CONDURANGO-GLYCOSIDE ASSOCIATIONS, PROCEDURES FOR THEIR PREPARATION, ANTITUMORS THAT INCLUDE THEM AND COMPOSITIONS WHICH THEY CONTAIN |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2769780A JPS56123999A (en) | 1980-03-05 | 1980-03-05 | Cundurango glycoside, its preparation and antitumor agent comprising it |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS56123999A true JPS56123999A (en) | 1981-09-29 |
JPS6251277B2 JPS6251277B2 (en) | 1987-10-29 |
Family
ID=12228164
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2769780A Granted JPS56123999A (en) | 1979-08-23 | 1980-03-05 | Cundurango glycoside, its preparation and antitumor agent comprising it |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56123999A (en) |
-
1980
- 1980-03-05 JP JP2769780A patent/JPS56123999A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS6251277B2 (en) | 1987-10-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS536413A (en) | Preparation of n-containing polysaccharides | |
JPS56123999A (en) | Cundurango glycoside, its preparation and antitumor agent comprising it | |
JPS5430221A (en) | Preparation of azo pigments | |
JPS5218832A (en) | Method of making cosmetic preparation | |
JPS5341494A (en) | Flavors and their preparation | |
JPS5436255A (en) | Novel sesquiterpene analogue, its preparation, and pharmatheutical containing the same | |
KR840004361A (en) | Plant extracts of the family "Hypoxidesi" (Hypoxidaceae) for the treatment of cancer | |
JPS55122724A (en) | Antidiabetic agent | |
JPS57165400A (en) | Saponin of astragali radix and its separation | |
JPS51144732A (en) | A remedy for hepatic failure | |
JPS52122612A (en) | Anti-tumor substance and its preparation | |
JPS56169700A (en) | Condurango glucoside b0, its preparation and antitumor agent consisting of the same | |
JPS52130698A (en) | Paper money pool mechanism | |
JPS5414951A (en) | Preparation of vitamin d derivatives | |
JPS51139694A (en) | Process for producing 'miso' | |
JPS5365809A (en) | Continuous preparation of tertiary alkyl ether | |
JPS53127808A (en) | Preparation of human albumin | |
JPS5742620A (en) | Novel antiulcer agent | |
JPS5321109A (en) | Purification of hexafluoropropylene epoxide | |
JPS5395932A (en) | Diphenyl ethers, process for their preparation and herbicides containing the same | |
JPS57128633A (en) | Use of insulin in order to remedy cancer | |
JPS5699785A (en) | Preparation of garlic liquor | |
JPS5271489A (en) | Synthesis of josamycin derivative | |
JPS5346937A (en) | Preparation of n-p-aminobenzoyl-n,-p-aminourea | |
ATE722T1 (en) | OCTAHYDRO-1H-BENZO(4,5)FU RO(3,2-E)ISOCHINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |