JPS56108786A - Acetamide derivative and its salt - Google Patents

Acetamide derivative and its salt

Info

Publication number
JPS56108786A
JPS56108786A JP934880A JP934880A JPS56108786A JP S56108786 A JPS56108786 A JP S56108786A JP 934880 A JP934880 A JP 934880A JP 934880 A JP934880 A JP 934880A JP S56108786 A JPS56108786 A JP S56108786A
Authority
JP
Japan
Prior art keywords
formula
thiazolyl
lower alkyl
salt
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP934880A
Other languages
Japanese (ja)
Other versions
JPS6254309B2 (en
Inventor
Mitsutaka Yoshida
Mitsuru Tanemura
Kiyoshige Ochi
Isao Matsunaga
Koji Mizuno
Shinichi Kaiho
Shunichi Hata
Yasuhiro Yamashita
Takashi Matsuno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Priority to JP934880A priority Critical patent/JPS56108786A/en
Publication of JPS56108786A publication Critical patent/JPS56108786A/en
Publication of JPS6254309B2 publication Critical patent/JPS6254309B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:The titled compound of formula I (X is O, S or its dioxide; R1 is H or lower alkyl; R2 is thiazolyl or thiazolinyl; R3 is H or lower alkyl).
EXAMPLE: N-(2-Thiazolyl)-2-(2-picolylthio)propionamide.
USE: Drug having antiphlogistic, immune activating, and antitumor activities.
PROCESS: The compound of formula I is prepared by reacting an acetic acid derivative of formula II or its reactive derivative at the carboxyl group (e.g. chloride, active ester, etc.) with 2-aminothiazole of formula III or 2-aminothiazoline in the presence of an assistant such as dicyclohexylcarbodiimide, etc. in a solvent such as benzene, chloroform, etc. The reaction is carried out if necessary in the presence of a base such as an alkali metal or pyridine.
COPYRIGHT: (C)1981,JPO&Japio
JP934880A 1980-01-31 1980-01-31 Acetamide derivative and its salt Granted JPS56108786A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP934880A JPS56108786A (en) 1980-01-31 1980-01-31 Acetamide derivative and its salt

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP934880A JPS56108786A (en) 1980-01-31 1980-01-31 Acetamide derivative and its salt

Publications (2)

Publication Number Publication Date
JPS56108786A true JPS56108786A (en) 1981-08-28
JPS6254309B2 JPS6254309B2 (en) 1987-11-13

Family

ID=11717960

Family Applications (1)

Application Number Title Priority Date Filing Date
JP934880A Granted JPS56108786A (en) 1980-01-31 1980-01-31 Acetamide derivative and its salt

Country Status (1)

Country Link
JP (1) JPS56108786A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010504373A (en) * 2006-09-25 2010-02-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Compounds that modulate the CB2 receptor

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010504373A (en) * 2006-09-25 2010-02-12 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Compounds that modulate the CB2 receptor

Also Published As

Publication number Publication date
JPS6254309B2 (en) 1987-11-13

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