JPS56108786A - Acetamide derivative and its salt - Google Patents
Acetamide derivative and its saltInfo
- Publication number
- JPS56108786A JPS56108786A JP934880A JP934880A JPS56108786A JP S56108786 A JPS56108786 A JP S56108786A JP 934880 A JP934880 A JP 934880A JP 934880 A JP934880 A JP 934880A JP S56108786 A JPS56108786 A JP S56108786A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- thiazolyl
- lower alkyl
- salt
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:The titled compound of formula I (X is O, S or its dioxide; R1 is H or lower alkyl; R2 is thiazolyl or thiazolinyl; R3 is H or lower alkyl).
EXAMPLE: N-(2-Thiazolyl)-2-(2-picolylthio)propionamide.
USE: Drug having antiphlogistic, immune activating, and antitumor activities.
PROCESS: The compound of formula I is prepared by reacting an acetic acid derivative of formula II or its reactive derivative at the carboxyl group (e.g. chloride, active ester, etc.) with 2-aminothiazole of formula III or 2-aminothiazoline in the presence of an assistant such as dicyclohexylcarbodiimide, etc. in a solvent such as benzene, chloroform, etc. The reaction is carried out if necessary in the presence of a base such as an alkali metal or pyridine.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP934880A JPS56108786A (en) | 1980-01-31 | 1980-01-31 | Acetamide derivative and its salt |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP934880A JPS56108786A (en) | 1980-01-31 | 1980-01-31 | Acetamide derivative and its salt |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS56108786A true JPS56108786A (en) | 1981-08-28 |
JPS6254309B2 JPS6254309B2 (en) | 1987-11-13 |
Family
ID=11717960
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP934880A Granted JPS56108786A (en) | 1980-01-31 | 1980-01-31 | Acetamide derivative and its salt |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56108786A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010504373A (en) * | 2006-09-25 | 2010-02-12 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Compounds that modulate the CB2 receptor |
-
1980
- 1980-01-31 JP JP934880A patent/JPS56108786A/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010504373A (en) * | 2006-09-25 | 2010-02-12 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Compounds that modulate the CB2 receptor |
Also Published As
Publication number | Publication date |
---|---|
JPS6254309B2 (en) | 1987-11-13 |
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