JPS5553298A - Water-soluble peptide glycan - Google Patents
Water-soluble peptide glycanInfo
- Publication number
- JPS5553298A JPS5553298A JP12805878A JP12805878A JPS5553298A JP S5553298 A JPS5553298 A JP S5553298A JP 12805878 A JP12805878 A JP 12805878A JP 12805878 A JP12805878 A JP 12805878A JP S5553298 A JPS5553298 A JP S5553298A
- Authority
- JP
- Japan
- Prior art keywords
- water
- peptide glycan
- compound
- spectrum
- treating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
NEW MATERIAL:A water-soluble peptide glycan having the following characteristics: (A) soluble in water, insoluble in ethanol, acetone, etc.; (B) molecular weight, 5×103-1×105 (gel permeation); (C) constituent amino sugars and amino acids, glucosamine, alanine, etc.; (D) constituent non-peptide glycan component, organo-phosphorus compound, etc. (E) UV spectrum, absorption edge of ≤230m; (F) IR spectrum, amide-absorption peaks at 1660 and 1550cm-1, OH-absorption peak at 1060cm-1; (G) mitogenic activity and immunological adjuvant activity, positive; (H) average chain length of sugar residue, 4 as N-acetylglycosamyl-(1,4)- N-acetylmuramic acid.
USE: Remedy and prophylaxis of malignant tumor.
PROCESS: The compound can be prepared by (1) culturing bacteria belonging to streptomyces genus in a medium, (2) mechanically disintegrating the cultured bacterial cells, (3) treating the crude cell walls obtained as a precipitate with protease, (4) treating the treated product with lysozyme, and (5) separating and purifying the objective compound.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12805878A JPS5553298A (en) | 1978-10-17 | 1978-10-17 | Water-soluble peptide glycan |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12805878A JPS5553298A (en) | 1978-10-17 | 1978-10-17 | Water-soluble peptide glycan |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5553298A true JPS5553298A (en) | 1980-04-18 |
Family
ID=14975429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP12805878A Pending JPS5553298A (en) | 1978-10-17 | 1978-10-17 | Water-soluble peptide glycan |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5553298A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5185321A (en) * | 1989-12-13 | 1993-02-09 | Nestec S.A. | Process for producing immunostimulants |
-
1978
- 1978-10-17 JP JP12805878A patent/JPS5553298A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5185321A (en) * | 1989-12-13 | 1993-02-09 | Nestec S.A. | Process for producing immunostimulants |
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