JPS5551064A - Novel aryloxazolidinone*oxazolidinethione* pyrrolidinone*pyrrolidine and thiazolidinone* their manufacture and their therapeutic application - Google Patents

Novel aryloxazolidinone*oxazolidinethione* pyrrolidinone*pyrrolidine and thiazolidinone* their manufacture and their therapeutic application

Info

Publication number
JPS5551064A
JPS5551064A JP7295479A JP7295479A JPS5551064A JP S5551064 A JPS5551064 A JP S5551064A JP 7295479 A JP7295479 A JP 7295479A JP 7295479 A JP7295479 A JP 7295479A JP S5551064 A JPS5551064 A JP S5551064A
Authority
JP
Japan
Prior art keywords
oxazolidinethione
aryloxazolidinone
thiazolidinone
pyrrolidinone
pyrrolidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP7295479A
Other languages
Japanese (ja)
Other versions
JPS635391B2 (en
Inventor
Douzon Koretsuto
Anshiya Jiyannfuransuwa
Buurujierii Gii
Dosuteru Fuiritsupu
Giyare Patoritsuku
Rakuuru Aran
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande SA filed Critical Delalande SA
Publication of JPS5551064A publication Critical patent/JPS5551064A/en
Publication of JPS635391B2 publication Critical patent/JPS635391B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, ***e
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63—Esters of sulfonic acids
    • C07C309/72—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/73—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/24—Oxygen atoms attached in position 2 with hydrocarbon radicals, substituted by oxygen atoms, attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/14—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP7295479A 1978-06-09 1979-06-09 Novel aryloxazolidinone*oxazolidinethione* pyrrolidinone*pyrrolidine and thiazolidinone* their manufacture and their therapeutic application Granted JPS5551064A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7817388A FR2428032A1 (en) 1978-06-09 1978-06-09 N-Aryl-azolidone cpds. - useful as psychotropic agents and antidepressants (NL 11.12.79)

Publications (2)

Publication Number Publication Date
JPS5551064A true JPS5551064A (en) 1980-04-14
JPS635391B2 JPS635391B2 (en) 1988-02-03

Family

ID=9209330

Family Applications (2)

Application Number Title Priority Date Filing Date
JP7295479A Granted JPS5551064A (en) 1978-06-09 1979-06-09 Novel aryloxazolidinone*oxazolidinethione* pyrrolidinone*pyrrolidine and thiazolidinone* their manufacture and their therapeutic application
JP6772281A Granted JPS56167666A (en) 1978-06-09 1981-05-07 N-aryloxazolidinone, pyrrolidinone and their manufacture

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP6772281A Granted JPS56167666A (en) 1978-06-09 1981-05-07 N-aryloxazolidinone, pyrrolidinone and their manufacture

Country Status (3)

Country Link
JP (2) JPS5551064A (en)
FR (1) FR2428032A1 (en)
ZA (1) ZA792799B (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5838273A (en) * 1981-02-25 1983-03-05 デラランデ・エス・エ− Novel 5-aminomethyloxazolidine derivative, manufacture and drug
JPS5980668A (en) * 1982-06-08 1984-05-10 デラランデ・エス・ア− Optically active derivative of n-arylated oxazolidin-2-one, manufacture and drug
JPS608277A (en) * 1983-06-07 1985-01-17 ザ・デュポン・メルク・ファーマシュウティカル・カンパニー Aminomethyloxooxazolidinylbenzene derivative
WO2007116960A1 (en) * 2006-04-06 2007-10-18 Research Foundation Itsuu Laboratory Oxazolidinone derivative having carbocyclic ring

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2506769A2 (en) * 1978-06-09 1982-12-03 Delalande Sa Cyano:pentyl:phenyl-methoxymethyl-oxazolidinone - useful as antidepressant
FR2458547B2 (en) * 1978-06-09 1986-05-16 Delalande Sa NOVEL AZOLONES N-ARYLE, THEIR PREPARATION PROCESS AND THEIR THERAPEUTIC APPLICATION
FR2603279B1 (en) * 1986-09-03 1988-12-16 Rech Ind BENZYLOXY-PHENYL-OXAZOLIDINONES, METHOD OF PREPARATION AND USE IN THERAPEUTICS
EP0259228B1 (en) * 1986-09-03 1992-06-03 Delalande S.A. 5-aminomethyl-2-oxazolidinone derivatives, their preparation and their therapeutical use
FR2609029B1 (en) * 1986-12-30 1989-12-08 Delalande Sa 5-AMINOETHYL DERIVATIVES OF OXAZOLIDINONE-2, THEIR PREPARATION PROCESS AND THEIR THERAPEUTIC APPLICATION

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1602544A (en) * 1968-10-29 1970-12-21 Acetylenic 2-oxazolidinones
GB1252101A (en) * 1969-03-18 1971-11-03
CH618682A5 (en) * 1975-11-07 1980-08-15 Ciba Geigy Ag

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5838273A (en) * 1981-02-25 1983-03-05 デラランデ・エス・エ− Novel 5-aminomethyloxazolidine derivative, manufacture and drug
JPH0261465B2 (en) * 1981-02-25 1990-12-20 Delalande Sa
JPS5980668A (en) * 1982-06-08 1984-05-10 デラランデ・エス・ア− Optically active derivative of n-arylated oxazolidin-2-one, manufacture and drug
JPS608277A (en) * 1983-06-07 1985-01-17 ザ・デュポン・メルク・ファーマシュウティカル・カンパニー Aminomethyloxooxazolidinylbenzene derivative
WO2007116960A1 (en) * 2006-04-06 2007-10-18 Research Foundation Itsuu Laboratory Oxazolidinone derivative having carbocyclic ring

Also Published As

Publication number Publication date
JPH039106B2 (en) 1991-02-07
FR2428032B1 (en) 1981-10-16
FR2428032A1 (en) 1980-01-04
JPS56167666A (en) 1981-12-23
JPS635391B2 (en) 1988-02-03
ZA792799B (en) 1980-08-27

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