JPS5549376A - Cephalosporin analog - Google Patents

Cephalosporin analog

Info

Publication number
JPS5549376A
JPS5549376A JP12240378A JP12240378A JPS5549376A JP S5549376 A JPS5549376 A JP S5549376A JP 12240378 A JP12240378 A JP 12240378A JP 12240378 A JP12240378 A JP 12240378A JP S5549376 A JPS5549376 A JP S5549376A
Authority
JP
Japan
Prior art keywords
azide
formula
alkyl
cephalosporins
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP12240378A
Other languages
Japanese (ja)
Inventor
Tadashi Hirata
Takehiro Ogasa
Hiromitsu Saito
Yoshihiro Nakamizo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP12240378A priority Critical patent/JPS5549376A/en
Priority to NO790955A priority patent/NO790955L/en
Priority to SE7902598A priority patent/SE7902598L/en
Priority to DK119979A priority patent/DK119979A/en
Priority to NL7902316A priority patent/NL7902316A/en
Priority to FR7907414A priority patent/FR2420537B1/en
Priority to CA324,178A priority patent/CA1133903A/en
Priority to US06/023,645 priority patent/US4291164A/en
Priority to AU45367/79A priority patent/AU528675B2/en
Priority to ES478919A priority patent/ES478919A1/en
Priority to CH278979A priority patent/CH642369A5/en
Priority to IT21290/79A priority patent/IT1115153B/en
Priority to AR275946A priority patent/AR226681A1/en
Priority to GB7910506A priority patent/GB2017102B/en
Priority to DE2911786A priority patent/DE2911786C2/en
Priority to ES486997A priority patent/ES486997A1/en
Priority to ES486995A priority patent/ES486995A1/en
Priority to ES486994A priority patent/ES486994A1/en
Priority to ES486996A priority patent/ES486996A1/en
Priority to ES486993A priority patent/ES486993A1/en
Publication of JPS5549376A publication Critical patent/JPS5549376A/en
Pending legal-status Critical Current

Links

Landscapes

  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

NEW MATERIAL:Cephalosporin analogs of formula I (X is amino, azide, phthalyl imino; R1 is H, halogen, hydroxyl, lower alkoxy, aryloxy; R2 is the same as R1 or lower alkyl, azide, nitrile; R3 is H, alkyl, aryl) and their salts.
EXAMPLE: (±) cis, 2-t-Butyloxyacrbonyl-7-azide-1-azabicyclo[4, 2, 0]octo-2-ene- 8-one.
USE: Synthetic intermediatedes of cephalosporins; the introduction of various kinds of acyl groups into the amino group of the compound of formula I in which X is primary amino gives cephalosporins having antibacterial activity.
PREPARATION: According to reaction equations, from compounds of formula II and III are obtained compounds of formula Ia where X is azide, phthalylimino, R1 is H, R2 is H, lower alkyl, R3 is alkyl, aryl, aralkyl.
COPYRIGHT: (C)1980,JPO&Japio
JP12240378A 1978-03-20 1978-10-04 Cephalosporin analog Pending JPS5549376A (en)

Priority Applications (20)

Application Number Priority Date Filing Date Title
JP12240378A JPS5549376A (en) 1978-10-04 1978-10-04 Cephalosporin analog
NO790955A NO790955L (en) 1978-03-25 1979-03-21 CEPHALOSPORINE ANALOGUE CARBACEFEM COMPOUNDS AND PROCEDURES FOR MANUFACTURE THEREOF
SE7902598A SE7902598L (en) 1978-03-25 1979-03-22 CEPHALOSPORINE ANALOGES
DK119979A DK119979A (en) 1978-03-25 1979-03-23 CEPHALOSPORINE ANALOG AND METHOD OF MANUFACTURE
NL7902316A NL7902316A (en) 1978-03-25 1979-03-23 CEPHALOSPORIN DERIVATIVES.
FR7907414A FR2420537B1 (en) 1978-03-25 1979-03-23 PRODUCTS SIMILAR TO CEPHALOSPORIN AND THEIR PREPARATION PROCESS
CA324,178A CA1133903A (en) 1978-03-25 1979-03-23 Cephalosporin analogs
US06/023,645 US4291164A (en) 1978-03-20 1979-03-23 Cephalosporin analogs and methods for production thereof
AU45367/79A AU528675B2 (en) 1978-03-25 1979-03-23 Cephalosporin analogs
ES478919A ES478919A1 (en) 1978-03-25 1979-03-23 A procedure for the production of cefalosporine analogs. (Machine-translation by Google Translate, not legally binding)
CH278979A CH642369A5 (en) 1978-03-25 1979-03-26 CEPHALOSPORIN ANALOGS.
IT21290/79A IT1115153B (en) 1978-03-25 1979-03-26 Cephalosporin analogues and procedure for their preparation
AR275946A AR226681A1 (en) 1978-03-25 1979-03-26 PROCEDURE FOR PRODUCING ANALOGS OF CEPHALOSPORIN
GB7910506A GB2017102B (en) 1978-03-25 1979-03-26 Cephalosporin analogues
DE2911786A DE2911786C2 (en) 1978-03-25 1979-03-26 Carbacephem derivatives and their uses
ES486997A ES486997A1 (en) 1978-03-25 1979-12-17 A procedure for the production of cefalosporine analogs. (Machine-translation by Google Translate, not legally binding)
ES486995A ES486995A1 (en) 1978-03-25 1979-12-17 A procedure for the preparation of a b-lactama (Machine-translation by Google Translate, not legally binding)
ES486994A ES486994A1 (en) 1978-03-25 1979-12-17 A procedure for the production of cefalosporine analogs. (Machine-translation by Google Translate, not legally binding)
ES486996A ES486996A1 (en) 1978-03-25 1979-12-17 A procedure for the production of cefalosporine analogs. (Machine-translation by Google Translate, not legally binding)
ES486993A ES486993A1 (en) 1978-03-25 1979-12-17 A procedure for the production of cefalosporine analogs. (Machine-translation by Google Translate, not legally binding)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12240378A JPS5549376A (en) 1978-10-04 1978-10-04 Cephalosporin analog

Publications (1)

Publication Number Publication Date
JPS5549376A true JPS5549376A (en) 1980-04-09

Family

ID=14834922

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12240378A Pending JPS5549376A (en) 1978-03-20 1978-10-04 Cephalosporin analog

Country Status (1)

Country Link
JP (1) JPS5549376A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5630976A (en) * 1979-08-24 1981-03-28 Kyowa Hakko Kogyo Co Ltd Optically active cephalosporin analog

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5630976A (en) * 1979-08-24 1981-03-28 Kyowa Hakko Kogyo Co Ltd Optically active cephalosporin analog
JPS6350356B2 (en) * 1979-08-24 1988-10-07 Kyowa Hakko Kogyo Kk

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