JPS5531050A - Preparation of 1h-indazoleacetic acid - Google Patents

Preparation of 1h-indazoleacetic acid

Info

Publication number
JPS5531050A
JPS5531050A JP10504278A JP10504278A JPS5531050A JP S5531050 A JPS5531050 A JP S5531050A JP 10504278 A JP10504278 A JP 10504278A JP 10504278 A JP10504278 A JP 10504278A JP S5531050 A JPS5531050 A JP S5531050A
Authority
JP
Japan
Prior art keywords
hydrazine
salt
formula
indazoleacetic
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP10504278A
Other languages
Japanese (ja)
Other versions
JPS604825B2 (en
Inventor
Kazuo Karigome
Hideo Yagi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Priority to JP10504278A priority Critical patent/JPS604825B2/en
Priority to AT79103147T priority patent/ATE1902T1/en
Priority to EP19790103147 priority patent/EP0008759B1/en
Priority to DE7979103147T priority patent/DE2964147D1/en
Priority to ES483699A priority patent/ES483699A1/en
Publication of JPS5531050A publication Critical patent/JPS5531050A/en
Publication of JPS604825B2 publication Critical patent/JPS604825B2/en
Expired legal-status Critical Current

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  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

PURPOSE: To obtain the title compound useful as an intermediate for the synthesis of plant growth regulators, and anti-inflammatory drugs, through simple procedures in high yield and purity, by reacting a substituted propionic acid or its salt with a hydrazine.
CONSTITUTION: A substituted propionic acid of formula I: (X is H, halogen, or lower alkoxy group) or its salt is reacted with a hydrazine (H) in the presence of a metal catalyst, e.g. Raney nickel, in a solvent, e.g. water or methanol, under basic conditions at room temperature or under heating, preferably under basic conditions, to give the IH-indazoleacetic acid derivative of formula II or its salt. Inexpensive hydrazine is preferably used as H. The compound of formula II wherein X is lower alkyl group is novel.
COPYRIGHT: (C)1980,JPO&Japio
JP10504278A 1978-08-28 1978-08-28 Method for producing 1H-indazole acetic acid derivative Expired JPS604825B2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP10504278A JPS604825B2 (en) 1978-08-28 1978-08-28 Method for producing 1H-indazole acetic acid derivative
AT79103147T ATE1902T1 (en) 1978-08-28 1979-08-27 PROCESS FOR THE PREPARATION OF 1H-INDAZOLE-3YLESSIGS[URE DERIVATIVES.
EP19790103147 EP0008759B1 (en) 1978-08-28 1979-08-27 New process for preparing an 1h-indazol-3-ylacetic acid derivative
DE7979103147T DE2964147D1 (en) 1978-08-28 1979-08-27 New process for preparing an 1h-indazol-3-ylacetic acid derivative
ES483699A ES483699A1 (en) 1978-08-28 1979-08-28 New process for preparing an 1H-indazol-3-ylacetic acid derivative.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10504278A JPS604825B2 (en) 1978-08-28 1978-08-28 Method for producing 1H-indazole acetic acid derivative

Publications (2)

Publication Number Publication Date
JPS5531050A true JPS5531050A (en) 1980-03-05
JPS604825B2 JPS604825B2 (en) 1985-02-06

Family

ID=14396939

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10504278A Expired JPS604825B2 (en) 1978-08-28 1978-08-28 Method for producing 1H-indazole acetic acid derivative

Country Status (1)

Country Link
JP (1) JPS604825B2 (en)

Also Published As

Publication number Publication date
JPS604825B2 (en) 1985-02-06

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