JPS5531050A - Preparation of 1h-indazoleacetic acid - Google Patents
Preparation of 1h-indazoleacetic acidInfo
- Publication number
- JPS5531050A JPS5531050A JP10504278A JP10504278A JPS5531050A JP S5531050 A JPS5531050 A JP S5531050A JP 10504278 A JP10504278 A JP 10504278A JP 10504278 A JP10504278 A JP 10504278A JP S5531050 A JPS5531050 A JP S5531050A
- Authority
- JP
- Japan
- Prior art keywords
- hydrazine
- salt
- formula
- indazoleacetic
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
PURPOSE: To obtain the title compound useful as an intermediate for the synthesis of plant growth regulators, and anti-inflammatory drugs, through simple procedures in high yield and purity, by reacting a substituted propionic acid or its salt with a hydrazine.
CONSTITUTION: A substituted propionic acid of formula I: (X is H, halogen, or lower alkoxy group) or its salt is reacted with a hydrazine (H) in the presence of a metal catalyst, e.g. Raney nickel, in a solvent, e.g. water or methanol, under basic conditions at room temperature or under heating, preferably under basic conditions, to give the IH-indazoleacetic acid derivative of formula II or its salt. Inexpensive hydrazine is preferably used as H. The compound of formula II wherein X is lower alkyl group is novel.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10504278A JPS604825B2 (en) | 1978-08-28 | 1978-08-28 | Method for producing 1H-indazole acetic acid derivative |
AT79103147T ATE1902T1 (en) | 1978-08-28 | 1979-08-27 | PROCESS FOR THE PREPARATION OF 1H-INDAZOLE-3YLESSIGS[URE DERIVATIVES. |
EP19790103147 EP0008759B1 (en) | 1978-08-28 | 1979-08-27 | New process for preparing an 1h-indazol-3-ylacetic acid derivative |
DE7979103147T DE2964147D1 (en) | 1978-08-28 | 1979-08-27 | New process for preparing an 1h-indazol-3-ylacetic acid derivative |
ES483699A ES483699A1 (en) | 1978-08-28 | 1979-08-28 | New process for preparing an 1H-indazol-3-ylacetic acid derivative. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10504278A JPS604825B2 (en) | 1978-08-28 | 1978-08-28 | Method for producing 1H-indazole acetic acid derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5531050A true JPS5531050A (en) | 1980-03-05 |
JPS604825B2 JPS604825B2 (en) | 1985-02-06 |
Family
ID=14396939
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10504278A Expired JPS604825B2 (en) | 1978-08-28 | 1978-08-28 | Method for producing 1H-indazole acetic acid derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS604825B2 (en) |
-
1978
- 1978-08-28 JP JP10504278A patent/JPS604825B2/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
JPS604825B2 (en) | 1985-02-06 |
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