JPS5515716A - Production of purine arabinoside - Google Patents

Production of purine arabinoside

Info

Publication number
JPS5515716A
JPS5515716A JP8728878A JP8728878A JPS5515716A JP S5515716 A JPS5515716 A JP S5515716A JP 8728878 A JP8728878 A JP 8728878A JP 8728878 A JP8728878 A JP 8728878A JP S5515716 A JPS5515716 A JP S5515716A
Authority
JP
Japan
Prior art keywords
purine
arabinoside
reaction
bacterium
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP8728878A
Other languages
Japanese (ja)
Other versions
JPS6214279B2 (en
Inventor
Takashi Udagawa
Takeshi Miyoshi
Hirokazu Morisawa
Akihiro Yamazaki
Fumihiro Yoshinaga
Koji Mitsuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Priority to JP8728878A priority Critical patent/JPS5515716A/en
Priority to US05/930,046 priority patent/US4371613A/en
Publication of JPS5515716A publication Critical patent/JPS5515716A/en
Publication of JPS6214279B2 publication Critical patent/JPS6214279B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PURPOSE: Purine arabinoside used as a drug having antiviral and carcinostatic activities is produced by reaction between specific compounds in the presence of a bacterium.
CONSTITUTION: The reaction between purine, or 2-, 6- and/or 8- substituted purine, or its riboside or ribotide and arabinose-1-phosphate is effected by the aid of a bacterium selected from pseudomonus, flavobacterium, achromobacter, salmonella, citrobacter, escherichia, clebsiella, enterobacter, aeromonus, serratia, proteus, xanthomonus, bacterium, etc., to form purine arabinoside or 2-,6- and/or 8-substituted purine arabinoside. The reaction is conducted by dissolving or dispersing the reactants in an aqeous reaction medium, keeping the temperature to 10W70°C and a pH to 4W10 for while. The results of the accumulation of the arabinoside according to kinds of bacteria is given in the table.
COPYRIGHT: (C)1980,JPO&Japio
JP8728878A 1977-08-10 1978-07-18 Production of purine arabinoside Granted JPS5515716A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP8728878A JPS5515716A (en) 1978-07-18 1978-07-18 Production of purine arabinoside
US05/930,046 US4371613A (en) 1977-08-10 1978-08-01 Method for producing purine arabinosides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8728878A JPS5515716A (en) 1978-07-18 1978-07-18 Production of purine arabinoside

Publications (2)

Publication Number Publication Date
JPS5515716A true JPS5515716A (en) 1980-02-04
JPS6214279B2 JPS6214279B2 (en) 1987-04-01

Family

ID=13910603

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8728878A Granted JPS5515716A (en) 1977-08-10 1978-07-18 Production of purine arabinoside

Country Status (1)

Country Link
JP (1) JPS5515716A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5495794A (en) * 1977-11-03 1979-07-28 Wellcome Found Enzymatic production of purinearabinonucleotides
JPS63310831A (en) * 1987-05-30 1988-12-19 ザ　ウエルカム　フアウンデーション　リミテッド Antiviral compound

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5495794A (en) * 1977-11-03 1979-07-28 Wellcome Found Enzymatic production of purinearabinonucleotides
JPS63310831A (en) * 1987-05-30 1988-12-19 ザ　ウエルカム　フアウンデーション　リミテッド Antiviral compound
JP2667873B2 (en) * 1987-05-30 1997-10-27 ザ ウエルカム フアウンデーション リミテッド Antiviral compounds

Also Published As

Publication number Publication date
JPS6214279B2 (en) 1987-04-01

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