JPS55153714A - Thiamine disulfide pharmaceutical preparation with little bitter taste and its preparation - Google Patents

Thiamine disulfide pharmaceutical preparation with little bitter taste and its preparation

Info

Publication number
JPS55153714A
JPS55153714A JP5142379A JP5142379A JPS55153714A JP S55153714 A JPS55153714 A JP S55153714A JP 5142379 A JP5142379 A JP 5142379A JP 5142379 A JP5142379 A JP 5142379A JP S55153714 A JPS55153714 A JP S55153714A
Authority
JP
Japan
Prior art keywords
preparation
bitter taste
pharmaceutical preparation
thiamine disulfide
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP5142379A
Other languages
Japanese (ja)
Inventor
Tadashi Azuma
Yuji Yamamoto
Emiko Araki
Fumio Ueda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KAWAI SEIYAKU KK
Original Assignee
KAWAI SEIYAKU KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KAWAI SEIYAKU KK filed Critical KAWAI SEIYAKU KK
Priority to JP5142379A priority Critical patent/JPS55153714A/en
Publication of JPS55153714A publication Critical patent/JPS55153714A/en
Pending legal-status Critical Current

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  • Medicinal Preparation (AREA)

Abstract

PURPOSE: To obtain the title pharmaceutical preparation with little bitter taste, useful as a raiw material for vitamin B1-containing pharmaceutical preparation, by dissolving a specific molar ratio of thiamine disulfide in a molten substance of a straight-chain saturated fatty acid, e.g., myristic acid, followed by setting through cooling and powdering.
CONSTITUTION: One part of wt. of thiamine disulfide is dissolved in 3W5pts.wt. of a 14W18C straight-chain saturated fatty acid being molten by heating. The resulting substance is set by cooling and powdered to give a thiamine disulfide pharmaceutical preparation with little bitter taste. Myristic acid, palmitic acid, and stearic acid are preferably cited as the fatty acid. Setting through mild cooling under gentle stirring lowers further the bitter taste of the preparation, improves the miscibility with an excipien, e.g., lactose, and is suitable for the production of powder. The preparation can be processed easily into granules, chewable drugs, etc.
COPYRIGHT: (C)1980,JPO&Japio
JP5142379A 1979-04-27 1979-04-27 Thiamine disulfide pharmaceutical preparation with little bitter taste and its preparation Pending JPS55153714A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP5142379A JPS55153714A (en) 1979-04-27 1979-04-27 Thiamine disulfide pharmaceutical preparation with little bitter taste and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5142379A JPS55153714A (en) 1979-04-27 1979-04-27 Thiamine disulfide pharmaceutical preparation with little bitter taste and its preparation

Publications (1)

Publication Number Publication Date
JPS55153714A true JPS55153714A (en) 1980-11-29

Family

ID=12886510

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5142379A Pending JPS55153714A (en) 1979-04-27 1979-04-27 Thiamine disulfide pharmaceutical preparation with little bitter taste and its preparation

Country Status (1)

Country Link
JP (1) JPS55153714A (en)

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