JPS55153714A - Thiamine disulfide pharmaceutical preparation with little bitter taste and its preparation - Google Patents
Thiamine disulfide pharmaceutical preparation with little bitter taste and its preparationInfo
- Publication number
- JPS55153714A JPS55153714A JP5142379A JP5142379A JPS55153714A JP S55153714 A JPS55153714 A JP S55153714A JP 5142379 A JP5142379 A JP 5142379A JP 5142379 A JP5142379 A JP 5142379A JP S55153714 A JPS55153714 A JP S55153714A
- Authority
- JP
- Japan
- Prior art keywords
- preparation
- bitter taste
- pharmaceutical preparation
- thiamine disulfide
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicinal Preparation (AREA)
Abstract
PURPOSE: To obtain the title pharmaceutical preparation with little bitter taste, useful as a raiw material for vitamin B1-containing pharmaceutical preparation, by dissolving a specific molar ratio of thiamine disulfide in a molten substance of a straight-chain saturated fatty acid, e.g., myristic acid, followed by setting through cooling and powdering.
CONSTITUTION: One part of wt. of thiamine disulfide is dissolved in 3W5pts.wt. of a 14W18C straight-chain saturated fatty acid being molten by heating. The resulting substance is set by cooling and powdered to give a thiamine disulfide pharmaceutical preparation with little bitter taste. Myristic acid, palmitic acid, and stearic acid are preferably cited as the fatty acid. Setting through mild cooling under gentle stirring lowers further the bitter taste of the preparation, improves the miscibility with an excipien, e.g., lactose, and is suitable for the production of powder. The preparation can be processed easily into granules, chewable drugs, etc.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5142379A JPS55153714A (en) | 1979-04-27 | 1979-04-27 | Thiamine disulfide pharmaceutical preparation with little bitter taste and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5142379A JPS55153714A (en) | 1979-04-27 | 1979-04-27 | Thiamine disulfide pharmaceutical preparation with little bitter taste and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS55153714A true JPS55153714A (en) | 1980-11-29 |
Family
ID=12886510
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP5142379A Pending JPS55153714A (en) | 1979-04-27 | 1979-04-27 | Thiamine disulfide pharmaceutical preparation with little bitter taste and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55153714A (en) |
-
1979
- 1979-04-27 JP JP5142379A patent/JPS55153714A/en active Pending
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