JPS55122727A - Acylation - Google Patents

Acylation

Info

Publication number
JPS55122727A
JPS55122727A JP3065879A JP3065879A JPS55122727A JP S55122727 A JPS55122727 A JP S55122727A JP 3065879 A JP3065879 A JP 3065879A JP 3065879 A JP3065879 A JP 3065879A JP S55122727 A JPS55122727 A JP S55122727A
Authority
JP
Japan
Prior art keywords
acylation
alcohol
amine
carboxylic acid
organic carboxylic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP3065879A
Other languages
Japanese (ja)
Inventor
Shigeo Shimizu
Hiroyuki Takano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NIPPON IYAKUHIN KAIHATSU KENKYUSHO KK
SANKEI YAKUHIN KK
Nippon Pharmaceutical Development Institute Co
Original Assignee
NIPPON IYAKUHIN KAIHATSU KENKYUSHO KK
SANKEI YAKUHIN KK
Nippon Pharmaceutical Development Institute Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NIPPON IYAKUHIN KAIHATSU KENKYUSHO KK, SANKEI YAKUHIN KK, Nippon Pharmaceutical Development Institute Co filed Critical NIPPON IYAKUHIN KAIHATSU KENKYUSHO KK
Priority to JP3065879A priority Critical patent/JPS55122727A/en
Publication of JPS55122727A publication Critical patent/JPS55122727A/en
Pending legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: To effect the acylation of an alcohol or an amine extremely easily and safely in short time, by using a mixture of a low-priced cyanuric chloride relatively stable in air and an organic carboxylic acid salt.
CONSTITUTION: An alcohol or amine is acylated by using a mixture of cyanuric chloride and an organic carboxylic acid salt (e.g., sodium salt, potassium salt, pyridine, etc.) in a solvent, e.g., dimethylformamide, dimethyl sulfoxide, etc. at 50W150°C for 10W30min with stirring under heating. For example, an ester is obtained by O-acylation of an alcohol and an acid amide is prepared by N-acylation of an amine. One mole of cyanuric chloride based on 2W3mol of an organic carboxylic acid is preferably used.
USE: A drug, pesticide, dye, pigment, plasticizer, sensitizing agent, spice, etc.
COPYRIGHT: (C)1980,JPO&Japio
JP3065879A 1979-03-16 1979-03-16 Acylation Pending JPS55122727A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP3065879A JPS55122727A (en) 1979-03-16 1979-03-16 Acylation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3065879A JPS55122727A (en) 1979-03-16 1979-03-16 Acylation

Publications (1)

Publication Number Publication Date
JPS55122727A true JPS55122727A (en) 1980-09-20

Family

ID=12309857

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3065879A Pending JPS55122727A (en) 1979-03-16 1979-03-16 Acylation

Country Status (1)

Country Link
JP (1) JPS55122727A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5885891A (en) * 1981-11-16 1983-05-23 Shionogi & Co Ltd Esterification of beta-lactam antibiotic

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5885891A (en) * 1981-11-16 1983-05-23 Shionogi & Co Ltd Esterification of beta-lactam antibiotic
JPH0354106B2 (en) * 1981-11-16 1991-08-19

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