JPS55122156A - C-type hepatitis virus-associated antigen - Google Patents

C-type hepatitis virus-associated antigen

Info

Publication number
JPS55122156A
JPS55122156A JP3033279A JP3033279A JPS55122156A JP S55122156 A JPS55122156 A JP S55122156A JP 3033279 A JP3033279 A JP 3033279A JP 3033279 A JP3033279 A JP 3033279A JP S55122156 A JPS55122156 A JP S55122156A
Authority
JP
Japan
Prior art keywords
type
antigen
type hepatitis
subjected
associated antigen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP3033279A
Other languages
Japanese (ja)
Inventor
Riyouichi Shiroji
Akira Tateda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chemo Sero Therapeutic Research Institute Kaketsuken
Original Assignee
Chemo Sero Therapeutic Research Institute Kaketsuken
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemo Sero Therapeutic Research Institute Kaketsuken filed Critical Chemo Sero Therapeutic Research Institute Kaketsuken
Priority to JP3033279A priority Critical patent/JPS55122156A/en
Publication of JPS55122156A publication Critical patent/JPS55122156A/en
Pending legal-status Critical Current

Links

Landscapes

  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

PURPOSE: To obtain C-type hepatitis virus-associated antigen by separating a special antigen from blood plasma (serum) of a patient diagnosed as non-A-type or non- B-type hepatitis after he had been subjected to transfusion of HBs antigen-negative blood.
CONSTITUTION: Blood plasma (serum) of a patient diagnosed as non-A-type or non-B-type hepatitis with multi-peak rise in GPT in particular and with a comparatively long period of incubation, obtained in the acute stage is used as a starting substance. This substance is subjected to gel filtration to obtain fractions (based on absorbance measurement of about 280nm). Among these fractions, on corresponding to a third peak P3 (refer to the drawing) is collected and subjected to column chromatography using an ion exchanger. The resulting product is condensed as necessary by using a precipitation method with polyethylene glycol, and refined by an ultra-centrifugal separation to obtain an objective antigen.
COPYRIGHT: (C)1980,JPO&Japio
JP3033279A 1979-03-14 1979-03-14 C-type hepatitis virus-associated antigen Pending JPS55122156A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP3033279A JPS55122156A (en) 1979-03-14 1979-03-14 C-type hepatitis virus-associated antigen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3033279A JPS55122156A (en) 1979-03-14 1979-03-14 C-type hepatitis virus-associated antigen

Publications (1)

Publication Number Publication Date
JPS55122156A true JPS55122156A (en) 1980-09-19

Family

ID=12300849

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3033279A Pending JPS55122156A (en) 1979-03-14 1979-03-14 C-type hepatitis virus-associated antigen

Country Status (1)

Country Link
JP (1) JPS55122156A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57175127A (en) * 1981-04-21 1982-10-28 Nakamura Tetsuo Substance and vaccine related to hepatitis nanb-1 and nanb-2 viral antigen
US4702909A (en) * 1982-05-05 1987-10-27 Louisiana State University A & M Non-A, non-B hepatitis antigen, antigen compositions, vaccine and diagnostic reagent
US5350671A (en) * 1987-11-18 1994-09-27 Chiron Corporation HCV immunoassays employing C domain antigens

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
THE LANCET=1978 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57175127A (en) * 1981-04-21 1982-10-28 Nakamura Tetsuo Substance and vaccine related to hepatitis nanb-1 and nanb-2 viral antigen
JPH0369892B2 (en) * 1981-04-21 1991-11-05 Nakamura Tetsuo
US4702909A (en) * 1982-05-05 1987-10-27 Louisiana State University A & M Non-A, non-B hepatitis antigen, antigen compositions, vaccine and diagnostic reagent
US5350671A (en) * 1987-11-18 1994-09-27 Chiron Corporation HCV immunoassays employing C domain antigens

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