JPS55122156A - C-type hepatitis virus-associated antigen - Google Patents
C-type hepatitis virus-associated antigenInfo
- Publication number
- JPS55122156A JPS55122156A JP3033279A JP3033279A JPS55122156A JP S55122156 A JPS55122156 A JP S55122156A JP 3033279 A JP3033279 A JP 3033279A JP 3033279 A JP3033279 A JP 3033279A JP S55122156 A JPS55122156 A JP S55122156A
- Authority
- JP
- Japan
- Prior art keywords
- type
- antigen
- type hepatitis
- subjected
- associated antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
PURPOSE: To obtain C-type hepatitis virus-associated antigen by separating a special antigen from blood plasma (serum) of a patient diagnosed as non-A-type or non- B-type hepatitis after he had been subjected to transfusion of HBs antigen-negative blood.
CONSTITUTION: Blood plasma (serum) of a patient diagnosed as non-A-type or non-B-type hepatitis with multi-peak rise in GPT in particular and with a comparatively long period of incubation, obtained in the acute stage is used as a starting substance. This substance is subjected to gel filtration to obtain fractions (based on absorbance measurement of about 280nm). Among these fractions, on corresponding to a third peak P3 (refer to the drawing) is collected and subjected to column chromatography using an ion exchanger. The resulting product is condensed as necessary by using a precipitation method with polyethylene glycol, and refined by an ultra-centrifugal separation to obtain an objective antigen.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3033279A JPS55122156A (en) | 1979-03-14 | 1979-03-14 | C-type hepatitis virus-associated antigen |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3033279A JPS55122156A (en) | 1979-03-14 | 1979-03-14 | C-type hepatitis virus-associated antigen |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS55122156A true JPS55122156A (en) | 1980-09-19 |
Family
ID=12300849
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP3033279A Pending JPS55122156A (en) | 1979-03-14 | 1979-03-14 | C-type hepatitis virus-associated antigen |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55122156A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57175127A (en) * | 1981-04-21 | 1982-10-28 | Nakamura Tetsuo | Substance and vaccine related to hepatitis nanb-1 and nanb-2 viral antigen |
US4702909A (en) * | 1982-05-05 | 1987-10-27 | Louisiana State University A & M | Non-A, non-B hepatitis antigen, antigen compositions, vaccine and diagnostic reagent |
US5350671A (en) * | 1987-11-18 | 1994-09-27 | Chiron Corporation | HCV immunoassays employing C domain antigens |
-
1979
- 1979-03-14 JP JP3033279A patent/JPS55122156A/en active Pending
Non-Patent Citations (1)
Title |
---|
THE LANCET=1978 * |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57175127A (en) * | 1981-04-21 | 1982-10-28 | Nakamura Tetsuo | Substance and vaccine related to hepatitis nanb-1 and nanb-2 viral antigen |
JPH0369892B2 (en) * | 1981-04-21 | 1991-11-05 | Nakamura Tetsuo | |
US4702909A (en) * | 1982-05-05 | 1987-10-27 | Louisiana State University A & M | Non-A, non-B hepatitis antigen, antigen compositions, vaccine and diagnostic reagent |
US5350671A (en) * | 1987-11-18 | 1994-09-27 | Chiron Corporation | HCV immunoassays employing C domain antigens |
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