JPS5510546A - Immunity sensor - Google Patents

Immunity sensor

Info

Publication number
JPS5510546A
JPS5510546A JP8360478A JP8360478A JPS5510546A JP S5510546 A JPS5510546 A JP S5510546A JP 8360478 A JP8360478 A JP 8360478A JP 8360478 A JP8360478 A JP 8360478A JP S5510546 A JPS5510546 A JP S5510546A
Authority
JP
Japan
Prior art keywords
combination
antigen
antibody
group
condensed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8360478A
Other languages
Japanese (ja)
Inventor
Tetsuo Cho
Masamichi Fujihira
Shunsaku Harie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AGC Inc
Original Assignee
Asahi Glass Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Glass Co Ltd filed Critical Asahi Glass Co Ltd
Priority to JP8360478A priority Critical patent/JPS5510546A/en
Publication of JPS5510546A publication Critical patent/JPS5510546A/en
Pending legal-status Critical Current

Links

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  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)

Abstract

PURPOSE: To prevent the antigen or the antibody from dissolving into the solution to secure the steady characteristics for the immunity sensor utilizing FET by fixing the antigen or the antibody in terms of the common combination and thus to strengthen the combination.
CONSTITUTION: A reaction is given as shown in Eq. I between the OH group on the surface of the electric insulator material covering over the semiconductor surface and the intermediate compound such as γ-amino-propyl triethoxy silane which is the silane coupling agent. After this, the carboxylic acid of the antigen or antibody R or the acid chloride derivative is condensed and then fixed by the amide combination. Otherwise the antigen or antibody R containing the carboxyl group or the OH group plus the OH group on the surface of the insulator material are dehydrated and condensed as shown in Eq. II. Thus, the ester combination or the ether combination is formed.
COPYRIGHT: (C)1980,JPO&Japio
JP8360478A 1978-07-11 1978-07-11 Immunity sensor Pending JPS5510546A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP8360478A JPS5510546A (en) 1978-07-11 1978-07-11 Immunity sensor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8360478A JPS5510546A (en) 1978-07-11 1978-07-11 Immunity sensor

Publications (1)

Publication Number Publication Date
JPS5510546A true JPS5510546A (en) 1980-01-25

Family

ID=13807076

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8360478A Pending JPS5510546A (en) 1978-07-11 1978-07-11 Immunity sensor

Country Status (1)

Country Link
JP (1) JPS5510546A (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58221153A (en) * 1982-06-14 1983-12-22 オ−ミクロン　コ−ポレ−ション Analyzer with semiconductive organic polymer element associating with analite bonding substance
JPS60171222A (en) * 1984-02-15 1985-09-04 Mitsubishi Steel Mfg Co Ltd Manufacture of zinc oxide by wet process
EP0155193A2 (en) * 1984-03-16 1985-09-18 Serono Diagnostics Limited Methods of assay
JPS62288546A (en) * 1986-06-06 1987-12-15 Seiko Instr & Electronics Ltd Crystal oscillator biosensor and analysis of living body-related substances using same
WO2004106891A2 (en) * 2003-05-22 2004-12-09 University Of Hawaii Ultrasensitive biochemical sensor
EP0874242B1 (en) * 1997-04-21 2005-02-23 Randox Laboratories Ltd. Device and apparatus for the simultaneous detection of multiple analytes
US7317216B2 (en) 2003-10-31 2008-01-08 University Of Hawaii Ultrasensitive biochemical sensing platform
US7692219B1 (en) 2004-06-25 2010-04-06 University Of Hawaii Ultrasensitive biosensors
US8192966B2 (en) 2004-03-18 2012-06-05 University Of Hawaii Biochemical concentrator and drug discovery

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58221153A (en) * 1982-06-14 1983-12-22 オ−ミクロン　コ−ポレ−ション Analyzer with semiconductive organic polymer element associating with analite bonding substance
JPH049254B2 (en) * 1982-06-14 1992-02-19
JPS60171222A (en) * 1984-02-15 1985-09-04 Mitsubishi Steel Mfg Co Ltd Manufacture of zinc oxide by wet process
EP0155193A2 (en) * 1984-03-16 1985-09-18 Serono Diagnostics Limited Methods of assay
JPS62288546A (en) * 1986-06-06 1987-12-15 Seiko Instr & Electronics Ltd Crystal oscillator biosensor and analysis of living body-related substances using same
EP0874242B1 (en) * 1997-04-21 2005-02-23 Randox Laboratories Ltd. Device and apparatus for the simultaneous detection of multiple analytes
WO2004106891A2 (en) * 2003-05-22 2004-12-09 University Of Hawaii Ultrasensitive biochemical sensor
WO2004106891A3 (en) * 2003-05-22 2005-03-03 Univ Hawaii Ultrasensitive biochemical sensor
US7291496B2 (en) 2003-05-22 2007-11-06 University Of Hawaii Ultrasensitive biochemical sensor
USRE43978E1 (en) 2003-05-22 2013-02-05 University Of Hawaii Ultrasensitive biochemical sensor
US7317216B2 (en) 2003-10-31 2008-01-08 University Of Hawaii Ultrasensitive biochemical sensing platform
US8192966B2 (en) 2004-03-18 2012-06-05 University Of Hawaii Biochemical concentrator and drug discovery
US7692219B1 (en) 2004-06-25 2010-04-06 University Of Hawaii Ultrasensitive biosensors
US8536661B1 (en) 2004-06-25 2013-09-17 University Of Hawaii Biosensor chip sensor protection methods
US10563252B2 (en) 2004-06-25 2020-02-18 University Of Hawaii Ultrasensitive biosensors

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