JPS549268A - Preparation of imidazole derivatives - Google Patents
Preparation of imidazole derivativesInfo
- Publication number
- JPS549268A JPS549268A JP7448077A JP7448077A JPS549268A JP S549268 A JPS549268 A JP S549268A JP 7448077 A JP7448077 A JP 7448077A JP 7448077 A JP7448077 A JP 7448077A JP S549268 A JPS549268 A JP S549268A
- Authority
- JP
- Japan
- Prior art keywords
- preparation
- imidazole derivatives
- dioxacetone
- intermediates
- aldehyde
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000002460 imidazoles Chemical class 0.000 title 1
- 229940079865 intestinal antiinfectives imidazole derivative Drugs 0.000 title 1
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 abstract 3
- QPLDLSVMHZLSFG-UHFFFAOYSA-N Copper oxide Chemical compound [Cu]=O QPLDLSVMHZLSFG-UHFFFAOYSA-N 0.000 abstract 2
- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 229960004643 cupric oxide Drugs 0.000 abstract 1
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000012452 mother liquor Substances 0.000 abstract 1
- 229910017604 nitric acid Inorganic materials 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 238000004064 recycling Methods 0.000 abstract 1
- LOIYMIARKYCTBW-OWOJBTEDSA-N trans-urocanic acid Chemical class OC(=O)\C=C\C1=CNC=N1 LOIYMIARKYCTBW-OWOJBTEDSA-N 0.000 abstract 1
Abstract
PURPOSE: To prepare the imidazole derivs., useful as intermediates for urocanic acid esters, in high yield and high purity by reaction of dioxacetone with aldehyde, etc. in the presence of cupric oxide, followed by oxidation of the resulting cpd. with nitric acid and recycling the mother liquor.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7448077A JPS549268A (en) | 1977-06-24 | 1977-06-24 | Preparation of imidazole derivatives |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7448077A JPS549268A (en) | 1977-06-24 | 1977-06-24 | Preparation of imidazole derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS549268A true JPS549268A (en) | 1979-01-24 |
Family
ID=13548467
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP7448077A Pending JPS549268A (en) | 1977-06-24 | 1977-06-24 | Preparation of imidazole derivatives |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS549268A (en) |
-
1977
- 1977-06-24 JP JP7448077A patent/JPS549268A/en active Pending
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