JPS5490179A - Antibiotic pseudomonic acid derivative and its preparation - Google Patents
Antibiotic pseudomonic acid derivative and its preparationInfo
- Publication number
- JPS5490179A JPS5490179A JP16081177A JP16081177A JPS5490179A JP S5490179 A JPS5490179 A JP S5490179A JP 16081177 A JP16081177 A JP 16081177A JP 16081177 A JP16081177 A JP 16081177A JP S5490179 A JPS5490179 A JP S5490179A
- Authority
- JP
- Japan
- Prior art keywords
- salt
- formula
- acid
- pseudomonic acid
- antibiotic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:An antibiotic pseudomonic acid of the formula or its salt.
USE: Antibacterials, having a powerful effect on Gram-positive bacteria, e.g. Staphylococcus aureus, Streptococcus pyogenes, and also effective for penicillin- or macroleide-resistant bacteria with a long duration. Useful for treatment of microbisms of men and animals.
PROCESS: A well-known antibiotic pseudomonic acid or its reactive derivative, e.g. alkyl ester, such as methyl ester, acid halide, acid anhydride, mixed acid anhydride, is reacted with hydroxylamine in a solvent, e.g. tetrahydrofuran or ethyl acetate, at a temperature of preferably -50°C to room temperature to give the objective compound of the formula. An inorganic salt, e.g. sodium, potassium, or aluminum salt, is preferably used as the salt of formula.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP52160811A JPS603311B2 (en) | 1977-12-27 | 1977-12-27 | Antibiotic pseudomonic acid derivatives and their production method |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP52160811A JPS603311B2 (en) | 1977-12-27 | 1977-12-27 | Antibiotic pseudomonic acid derivatives and their production method |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5490179A true JPS5490179A (en) | 1979-07-17 |
JPS603311B2 JPS603311B2 (en) | 1985-01-26 |
Family
ID=15722930
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP52160811A Expired JPS603311B2 (en) | 1977-12-27 | 1977-12-27 | Antibiotic pseudomonic acid derivatives and their production method |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS603311B2 (en) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5292892A (en) * | 1991-05-07 | 1994-03-08 | Sankyo Company, Limited | Anti-bacterial compound and pharmaceutical compositions thereof |
US5380723A (en) * | 1991-10-07 | 1995-01-10 | Nisshin Flour Milling Co., Ltd. | Indole derivatives |
US5399711A (en) * | 1992-09-18 | 1995-03-21 | Sankyo Company, Limited | Thiomarinol compounds |
JP2019073676A (en) * | 2017-05-25 | 2019-05-16 | 三菱ケミカル株式会社 | Epoxy resin, epoxy resin-containing composition, and cured product thereof |
-
1977
- 1977-12-27 JP JP52160811A patent/JPS603311B2/en not_active Expired
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5292892A (en) * | 1991-05-07 | 1994-03-08 | Sankyo Company, Limited | Anti-bacterial compound and pharmaceutical compositions thereof |
US5405762A (en) * | 1991-05-07 | 1995-04-11 | Sankyo Company, Limited | Culture of alteromonas and process of using the same to produce an antibacterial compound |
US5380723A (en) * | 1991-10-07 | 1995-01-10 | Nisshin Flour Milling Co., Ltd. | Indole derivatives |
US5399711A (en) * | 1992-09-18 | 1995-03-21 | Sankyo Company, Limited | Thiomarinol compounds |
JP2019073676A (en) * | 2017-05-25 | 2019-05-16 | 三菱ケミカル株式会社 | Epoxy resin, epoxy resin-containing composition, and cured product thereof |
Also Published As
Publication number | Publication date |
---|---|
JPS603311B2 (en) | 1985-01-26 |
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