JPS5435293A - Carbohydrate derivative of milbemycine and production - Google Patents

Carbohydrate derivative of milbemycine and production

Info

Publication number
JPS5435293A
JPS5435293A JP4183378A JP4183378A JPS5435293A JP S5435293 A JPS5435293 A JP S5435293A JP 4183378 A JP4183378 A JP 4183378A JP 4183378 A JP4183378 A JP 4183378A JP S5435293 A JPS5435293 A JP S5435293A
Authority
JP
Japan
Prior art keywords
milbemycine
production
carbohydrate derivative
carbohydrate
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP4183378A
Other languages
Japanese (ja)
Inventor
Haabaato Fuitsushiyaa Maikeru
Rii Tooruman Richiyaado
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/786,157 external-priority patent/US4134973A/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of JPS5435293A publication Critical patent/JPS5435293A/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
    • C07D493/20—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP4183378A 1977-04-11 1978-04-11 Carbohydrate derivative of milbemycine and production Pending JPS5435293A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/786,157 US4134973A (en) 1977-04-11 1977-04-11 Carbohydrate derivatives of milbemycin and processes therefor
US05/852,403 US4156720A (en) 1977-04-11 1977-11-17 Carbohydrate derivatives of milbemycin and processes therefor

Publications (1)

Publication Number Publication Date
JPS5435293A true JPS5435293A (en) 1979-03-15

Family

ID=27120508

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4183378A Pending JPS5435293A (en) 1977-04-11 1978-04-11 Carbohydrate derivative of milbemycine and production

Country Status (5)

Country Link
JP (1) JPS5435293A (en)
AU (1) AU517287B2 (en)
FR (1) FR2387231A1 (en)
GB (1) GB1579118A (en)
NZ (1) NZ186851A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02270879A (en) * 1989-01-19 1990-11-05 Merck & Co Inc Abelmecutin derivative
JP2008511564A (en) * 2004-09-03 2008-04-17 シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト Avermectin, avermectin monosaccharide and avermectin aglycone derivatives
JP2017515883A (en) * 2014-03-10 2017-06-15 浙江海正薬業股▲ふん▼有限公司Ｚｈｅｊｉａｎｇ Ｈｉｓｕｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌ ＣＯ．，ＬＴＤ． Sixteen-membered macrolide compounds and their use

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4203976A (en) * 1978-08-02 1980-05-20 Merck & Co., Inc. Sugar derivatives of C-076 compounds
US4200581A (en) * 1978-08-04 1980-04-29 Merck & Co., Inc. Alkyl derivatives of C-076 compounds
US4378353A (en) * 1981-02-17 1983-03-29 Merck & Co., Inc. Novel C-076 compounds
US4412991A (en) * 1981-08-28 1983-11-01 Merck & Co., Inc. 22-Hydroxy derivatives of C-076 compounds, pharmaceutical compositions and method of use
NZ201681A (en) * 1981-09-03 1985-11-08 Merck & Co Inc Avermectin derivatives and parasiticidal compositions
JPS59108785A (en) * 1982-11-25 1984-06-23 Sankyo Co Ltd 5-oxime derivative of milbemycins
US4469682A (en) * 1983-01-28 1984-09-04 Merck & Co., Inc. Avermectin and milbemycin phosphate esters, pharmaceutical compositions, and method of use
JPS60126289A (en) * 1983-11-14 1985-07-05 Sankyo Co Ltd 5-carbonate derivative of milbemycin
EP0180539A1 (en) * 1984-09-18 1986-05-07 Ciba-Geigy Ag 13-Halo- and 13-hydroxymilbemycin
GB2168345B (en) * 1984-12-14 1988-05-25 Ciba Geigy Ag Pesticidal 13b-substituted milbemycin derivatives
EP0185623A1 (en) * 1984-12-21 1986-06-25 Ciba-Geigy Ag Milbemycin derivatives for combating insects and parasites
NZ215917A (en) * 1985-05-02 1989-10-27 Merck & Co Inc 22-oh milbemycin derivatives and parasiticidal compositions
US4789684A (en) * 1985-05-02 1988-12-06 Merck & Co., Inc. Anthelmintic fermentation products of microorganisms
GB8726730D0 (en) * 1987-11-14 1987-12-16 Pfizer Ltd Antiparasitic agents
US5055454A (en) * 1989-10-30 1991-10-08 Merck & Co., Inc. 13-epi-avermectin derivatives useful as antiparasitic agents
US5114930A (en) * 1990-05-14 1992-05-19 Merck & Co., Inc. Avermectin derivatives with a spacer inserted between the disaccharide and the aglycone useful as antiparasitic agents
EP0481672A1 (en) * 1990-10-15 1992-04-22 Merck & Co. Inc. 5Beta- and 13beta ivermectin monoglucopyranosides
NZ240150A (en) * 1990-10-15 1993-07-27 Merck & Co Inc Fermentation medium and its use in the production of ivermectin derivatives
CA2259469A1 (en) 1996-06-05 1997-12-11 Ashmont Holdings Limited Injectable compositions

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4914624A (en) * 1972-06-08 1974-02-08
SE434277B (en) * 1976-04-19 1984-07-16 Merck & Co Inc SET TO MAKE NEW ANTIHELMINTICALLY EFFECTIVE ASSOCIATIONS BY CULTIVATING STREPTOMYCS AVERMITILIS

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02270879A (en) * 1989-01-19 1990-11-05 Merck & Co Inc Abelmecutin derivative
JP2505901B2 (en) * 1989-01-19 1996-06-12 メルク エンド カムパニー インコーポレーテツド Avermectin derivative
JP2008511564A (en) * 2004-09-03 2008-04-17 シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト Avermectin, avermectin monosaccharide and avermectin aglycone derivatives
JP2017515883A (en) * 2014-03-10 2017-06-15 浙江海正薬業股▲ふん▼有限公司Ｚｈｅｊｉａｎｇ Ｈｉｓｕｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌ ＣＯ．，ＬＴＤ． Sixteen-membered macrolide compounds and their use

Also Published As

Publication number Publication date
FR2387231A1 (en) 1978-11-10
AU3476078A (en) 1979-10-11
AU517287B2 (en) 1981-07-23
NZ186851A (en) 1984-12-14
FR2387231B1 (en) 1982-05-21
GB1579118A (en) 1980-11-12

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