JPS54135300A - Preparation of geldanamycin and other antibiotics - Google Patents

Preparation of geldanamycin and other antibiotics

Info

Publication number
JPS54135300A
JPS54135300A JP4022978A JP4022978A JPS54135300A JP S54135300 A JPS54135300 A JP S54135300A JP 4022978 A JP4022978 A JP 4022978A JP 4022978 A JP4022978 A JP 4022978A JP S54135300 A JPS54135300 A JP S54135300A
Authority
JP
Japan
Prior art keywords
geldanamycin
antibiotics
prepare
novel strain
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP4022978A
Other languages
Japanese (ja)
Other versions
JPS615713B2 (en
Inventor
Hiroshi Yonehara
Nozomi Otake
Kazukiyo Onodera
Tomoyoshi Segawa
Keien Kiyo
Tetsuo Sasaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CHIYUUGOKU SHINYAKU KOUGIYOU K
CHUGOKU SHINYAKU KOGYO KOFUN YUUGENKOUSHI
TOUBISHI YAKUHIN KOGYO KK
Tobishi Pharmaceutical Co Ltd
Nisshin Seifun Group Inc
Original Assignee
CHIYUUGOKU SHINYAKU KOUGIYOU K
CHUGOKU SHINYAKU KOGYO KOFUN YUUGENKOUSHI
TOUBISHI YAKUHIN KOGYO KK
Tobishi Pharmaceutical Co Ltd
Nisshin Seifun Group Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CHIYUUGOKU SHINYAKU KOUGIYOU K, CHUGOKU SHINYAKU KOGYO KOFUN YUUGENKOUSHI, TOUBISHI YAKUHIN KOGYO KK, Tobishi Pharmaceutical Co Ltd, Nisshin Seifun Group Inc filed Critical CHIYUUGOKU SHINYAKU KOUGIYOU K
Priority to JP4022978A priority Critical patent/JPS54135300A/en
Publication of JPS54135300A publication Critical patent/JPS54135300A/en
Publication of JPS615713B2 publication Critical patent/JPS615713B2/ja
Granted legal-status Critical Current

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

PURPOSE: To prepare geldanamycin and other three antibiotics, by the use of a novel strain capable of producing geldanamycin, etc.
CONSTITUTION: To prepare geldanamycin, 17-O-demethylgeldanamycin, 6-(3- methyl-2-butenyl)-indole, and enterocin, separately or as a mixture, by the aerobical cultivation of a novel strain streptomyces hygroscopicus B-434 (actinomyces) at 35W 45°C pref. in a liquid medium containing a carbon source such as D-glucose, a nitrogen source such as soybean flour, etc. by submerged technique, if necessary using a silicone oil or a vegetable oil as a defoaming agent.
COPYRIGHT: (C)1979,JPO&Japio
JP4022978A 1978-04-07 1978-04-07 Preparation of geldanamycin and other antibiotics Granted JPS54135300A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP4022978A JPS54135300A (en) 1978-04-07 1978-04-07 Preparation of geldanamycin and other antibiotics

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4022978A JPS54135300A (en) 1978-04-07 1978-04-07 Preparation of geldanamycin and other antibiotics

Publications (2)

Publication Number Publication Date
JPS54135300A true JPS54135300A (en) 1979-10-20
JPS615713B2 JPS615713B2 (en) 1986-02-20

Family

ID=12574901

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4022978A Granted JPS54135300A (en) 1978-04-07 1978-04-07 Preparation of geldanamycin and other antibiotics

Country Status (1)

Country Link
JP (1) JPS54135300A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4946779A (en) * 1981-04-13 1990-08-07 Takeda Chemical Industries, Ltd. Pseudo-aminosugars, their production and use
ES2156526A1 (en) * 1999-01-20 2001-06-16 Smithkline Beecham Sa New atherosclerosis treatment metabolites comprises Streptomyces cacaoi metabolites inhibiting monocyte protein
US20110034686A1 (en) * 2008-04-21 2011-02-10 Nitin Sopanrao Patil Process for Isolation and Purification of Geldanamycin
CN106191156A (en) * 2016-08-01 2016-12-07 上海交通大学 The method improving Ge Erdeng element fermentation level

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4946779A (en) * 1981-04-13 1990-08-07 Takeda Chemical Industries, Ltd. Pseudo-aminosugars, their production and use
ES2156526A1 (en) * 1999-01-20 2001-06-16 Smithkline Beecham Sa New atherosclerosis treatment metabolites comprises Streptomyces cacaoi metabolites inhibiting monocyte protein
US20110034686A1 (en) * 2008-04-21 2011-02-10 Nitin Sopanrao Patil Process for Isolation and Purification of Geldanamycin
CN106191156A (en) * 2016-08-01 2016-12-07 上海交通大学 The method improving Ge Erdeng element fermentation level
CN106191156B (en) * 2016-08-01 2019-05-07 上海交通大学 The method for improving Ge Erdeng element fermentation level

Also Published As

Publication number Publication date
JPS615713B2 (en) 1986-02-20

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