JPS54128598A - Antibiotic c-15003pdm - Google Patents
Antibiotic c-15003pdmInfo
- Publication number
- JPS54128598A JPS54128598A JP3464578A JP3464578A JPS54128598A JP S54128598 A JPS54128598 A JP S54128598A JP 3464578 A JP3464578 A JP 3464578A JP 3464578 A JP3464578 A JP 3464578A JP S54128598 A JPS54128598 A JP S54128598A
- Authority
- JP
- Japan
- Prior art keywords
- pdm
- antibiotic
- formula
- 15003pdm
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:An antibiotic C-15003PDM of formula I: (R is H or ≤5C alkanoyl group). General term of PDM-0, PDM-1, PDM-2, PDM-3, and PDM-4.
USE: Antibiotics having antimicrobic and oncostatic activities.
PROCESS: An antibiotic C-15003 of formula II is brought into contact with cultured or treated substances of microorganisms, e.g. Bacillus megaterium IFO12108 (FERM-P No.12108), which belong to the genuses Bacillus, Streptomyces, or Actinomycetes, and have an ability to convert the -OCH3 group of the 20-position of the antibiotic C-15003 into a hydroxyl group, and their variation strains, to prepare the compound of formula I.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3464578A JPS54128598A (en) | 1978-03-24 | 1978-03-24 | Antibiotic c-15003pdm |
GR58533A GR63147B (en) | 1978-03-24 | 1979-03-07 | Preparation process of demethyl maytansinoids |
ES478706A ES478706A1 (en) | 1978-03-24 | 1979-03-16 | Demethyl maytansinoids and methods for producing them. |
CA000323717A CA1144096A (en) | 1978-03-24 | 1979-03-19 | Demethyl maytansinoids |
AU45246/79A AU519911B2 (en) | 1978-03-24 | 1979-03-19 | Demethyl maytansinoids |
ZA791350A ZA791350B (en) | 1978-03-24 | 1979-03-21 | Demethyl maytansinoids |
PL1979214307A PL124051B1 (en) | 1978-03-24 | 1979-03-22 | Process for preparing novel demethylmaytansynoidic compounds |
PT69382A PT69382A (en) | 1978-03-24 | 1979-03-22 | Demethyl maytansinoids |
DK121279A DK121279A (en) | 1978-03-24 | 1979-03-23 | DEMETHYLMAYTANSINOIDS AND METHODS FOR MANUFACTURE THEREOF |
EP79300469A EP0004466B1 (en) | 1978-03-24 | 1979-03-23 | Demethyl maytansinoids and methods for producing them |
DE7979300469T DE2961940D1 (en) | 1978-03-24 | 1979-03-23 | Demethyl maytansinoids and methods for producing them |
AT0219179A AT362872B (en) | 1978-03-24 | 1979-03-23 | METHOD FOR PRODUCING NEW DEMETHYLMAYTANSINOIDS |
US06/153,522 US4307016A (en) | 1978-03-24 | 1980-05-27 | Demethyl maytansinoids |
US06/290,943 US4361650A (en) | 1978-03-24 | 1981-08-07 | Fermentation process of preparing demethyl maytansinoids |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3464578A JPS54128598A (en) | 1978-03-24 | 1978-03-24 | Antibiotic c-15003pdm |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS54128598A true JPS54128598A (en) | 1979-10-05 |
Family
ID=12420166
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP3464578A Pending JPS54128598A (en) | 1978-03-24 | 1978-03-24 | Antibiotic c-15003pdm |
Country Status (2)
Country | Link |
---|---|
JP (1) | JPS54128598A (en) |
ZA (1) | ZA791350B (en) |
-
1978
- 1978-03-24 JP JP3464578A patent/JPS54128598A/en active Pending
-
1979
- 1979-03-21 ZA ZA791350A patent/ZA791350B/en unknown
Also Published As
Publication number | Publication date |
---|---|
ZA791350B (en) | 1980-04-30 |
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