JPS54112864A - Novel imidazole derivative, its mineral acid salt, and their preparation - Google Patents
Novel imidazole derivative, its mineral acid salt, and their preparationInfo
- Publication number
- JPS54112864A JPS54112864A JP1847778A JP1847778A JPS54112864A JP S54112864 A JPS54112864 A JP S54112864A JP 1847778 A JP1847778 A JP 1847778A JP 1847778 A JP1847778 A JP 1847778A JP S54112864 A JPS54112864 A JP S54112864A
- Authority
- JP
- Japan
- Prior art keywords
- agent
- mineral acid
- acid salt
- substituted
- imidazole derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:2-Substituted-amino-4,5-diarylaminoimidazole of formula I (R1 is (substituted) 1-8C alkyl, aryl, especially, methyl, ethyl, tolyl, benzyl, substituted benzyl; R2,3 are (substituted) aryl, especially phenyl, tolyl, p-chlorophenyl), and its mineral acid salt (especially hydrochloride, nitrate).
EXAMPLE: 2-Methylamino-4,5-diphenylimidazole.
USE: Analgesic and antiphlogistic agent. It is also expected to be useful as an anti- viral agent, anti-allergic agent, immuno-inhibiting or accelerating agent, anti-ulcer agent, anthelmintic agent, etc.
PROCESS: The imidazole derivative I or its mineral acid salt is obtained by hydrogenating the compound II in the presence of a catalyst (pref. Pt oxide, Pd-C, Raney Ni, etc.,), and, if necessary, treating with a mineral acid.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1847778A JPS54112864A (en) | 1978-02-22 | 1978-02-22 | Novel imidazole derivative, its mineral acid salt, and their preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1847778A JPS54112864A (en) | 1978-02-22 | 1978-02-22 | Novel imidazole derivative, its mineral acid salt, and their preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS54112864A true JPS54112864A (en) | 1979-09-04 |
Family
ID=11972713
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP1847778A Pending JPS54112864A (en) | 1978-02-22 | 1978-02-22 | Novel imidazole derivative, its mineral acid salt, and their preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS54112864A (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001044203A1 (en) * | 1999-12-17 | 2001-06-21 | The Procter & Gamble Company | N-(1-phenylethyl)-5-phenyl-imidazole-2-amine compounds, their compositions and uses |
US6552033B1 (en) | 2000-05-16 | 2003-04-22 | The Procter & Gamble Co. | Imidazo-containing heterocyclic compounds, their compositions and uses |
US6596739B2 (en) | 2000-03-29 | 2003-07-22 | The Procter & Gamble Company | N-(1-phenylethyl)-5-phenyl-imidazole-2-amine compounds, their compositions and uses |
US7326792B2 (en) | 2003-07-21 | 2008-02-05 | Aventis Pharmaceuticals Inc. | Heterocyclic compounds as P2X7 ion channel blockers |
EP2513064B1 (en) * | 2009-12-17 | 2018-07-04 | Katholieke Universiteit Leuven, K.U. Leuven R&D | Compounds, compositions and methods for controlling biofilms |
-
1978
- 1978-02-22 JP JP1847778A patent/JPS54112864A/en active Pending
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001044203A1 (en) * | 1999-12-17 | 2001-06-21 | The Procter & Gamble Company | N-(1-phenylethyl)-5-phenyl-imidazole-2-amine compounds, their compositions and uses |
US6596739B2 (en) | 2000-03-29 | 2003-07-22 | The Procter & Gamble Company | N-(1-phenylethyl)-5-phenyl-imidazole-2-amine compounds, their compositions and uses |
US6552033B1 (en) | 2000-05-16 | 2003-04-22 | The Procter & Gamble Co. | Imidazo-containing heterocyclic compounds, their compositions and uses |
US7326792B2 (en) | 2003-07-21 | 2008-02-05 | Aventis Pharmaceuticals Inc. | Heterocyclic compounds as P2X7 ion channel blockers |
US7741493B2 (en) | 2003-07-21 | 2010-06-22 | Aventis Pharmaceuticals Inc. | Heterocyclic compounds as P2X7 ion channel blockers |
EP2513064B1 (en) * | 2009-12-17 | 2018-07-04 | Katholieke Universiteit Leuven, K.U. Leuven R&D | Compounds, compositions and methods for controlling biofilms |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL47061A (en) | 1-aryl and aralkyl imidazole derivatives and process for their manufacture | |
IE791565L (en) | Crop cutting apparatus | |
JPS54112864A (en) | Novel imidazole derivative, its mineral acid salt, and their preparation | |
JPS5448798A (en) | 3-tetrazolyl-1-azaxanthone derivative and its preparation | |
JPS57183768A (en) | 4-methyl-5-(o-carboxyphenyl)carbamoylthiazole derivative and its preparation | |
JPS5692887A (en) | N-substituted imidazole derivative | |
GB1434757A (en) | Method and composition for the control of fertility | |
JPS5754175A (en) | Novel 3-aminoindazole derivative | |
ES8305377A1 (en) | Nitrosourea derivatives, a process for preparing same and therapeutic compositions. | |
JPS5753480A (en) | Tetrahydro-1-alkylthiophenium derivative | |
ES483699A1 (en) | New process for preparing an 1H-indazol-3-ylacetic acid derivative. | |
JPS51115402A (en) | Process for preparation of alpha-amino acid | |
JPS5651483A (en) | 1-azaxanthone 3-carboxylic acid derivative and its preparation | |
KR830003487A (en) | Method for preparing benzodiazepines derivatives | |
JPS5610173A (en) | Analgesic | |
JPS55100364A (en) | Pyridonecarboxylic acid derivative and its salt | |
JPS5551065A (en) | Aminopyrrole derivative | |
JPS5646845A (en) | Preparation of aromatic amino compound | |
JPS51122032A (en) | Process for preparation of 2-phenyl propyl alcohol | |
JPS54106498A (en) | Carbostyril derivative | |
GB762720A (en) | Novel morpholinomethyl-phenyl derivatives and the manufacture thereof | |
JPS6479158A (en) | 2-nitroimidazole derivative | |
JPS54109973A (en) | Novel imidazole derivative | |
JPS55160769A (en) | Hydrazinophthalazine derivative | |
JPS55143963A (en) | Novel nitro compound and its preparation |