JPS54112864A - Novel imidazole derivative, its mineral acid salt, and their preparation - Google Patents

Novel imidazole derivative, its mineral acid salt, and their preparation

Info

Publication number
JPS54112864A
JPS54112864A JP1847778A JP1847778A JPS54112864A JP S54112864 A JPS54112864 A JP S54112864A JP 1847778 A JP1847778 A JP 1847778A JP 1847778 A JP1847778 A JP 1847778A JP S54112864 A JPS54112864 A JP S54112864A
Authority
JP
Japan
Prior art keywords
agent
mineral acid
acid salt
substituted
imidazole derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP1847778A
Other languages
Japanese (ja)
Inventor
Tamio Nishimura
Atsuji Kitajima
Seiji Kurozumi
Keiji Komoriya
Yoshinobu Hashimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Priority to JP1847778A priority Critical patent/JPS54112864A/en
Publication of JPS54112864A publication Critical patent/JPS54112864A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:2-Substituted-amino-4,5-diarylaminoimidazole of formula I (R1 is (substituted) 1-8C alkyl, aryl, especially, methyl, ethyl, tolyl, benzyl, substituted benzyl; R2,3 are (substituted) aryl, especially phenyl, tolyl, p-chlorophenyl), and its mineral acid salt (especially hydrochloride, nitrate).
EXAMPLE: 2-Methylamino-4,5-diphenylimidazole.
USE: Analgesic and antiphlogistic agent. It is also expected to be useful as an anti- viral agent, anti-allergic agent, immuno-inhibiting or accelerating agent, anti-ulcer agent, anthelmintic agent, etc.
PROCESS: The imidazole derivative I or its mineral acid salt is obtained by hydrogenating the compound II in the presence of a catalyst (pref. Pt oxide, Pd-C, Raney Ni, etc.,), and, if necessary, treating with a mineral acid.
COPYRIGHT: (C)1979,JPO&Japio
JP1847778A 1978-02-22 1978-02-22 Novel imidazole derivative, its mineral acid salt, and their preparation Pending JPS54112864A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP1847778A JPS54112864A (en) 1978-02-22 1978-02-22 Novel imidazole derivative, its mineral acid salt, and their preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1847778A JPS54112864A (en) 1978-02-22 1978-02-22 Novel imidazole derivative, its mineral acid salt, and their preparation

Publications (1)

Publication Number Publication Date
JPS54112864A true JPS54112864A (en) 1979-09-04

Family

ID=11972713

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1847778A Pending JPS54112864A (en) 1978-02-22 1978-02-22 Novel imidazole derivative, its mineral acid salt, and their preparation

Country Status (1)

Country Link
JP (1) JPS54112864A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001044203A1 (en) * 1999-12-17 2001-06-21 The Procter & Gamble Company N-(1-phenylethyl)-5-phenyl-imidazole-2-amine compounds, their compositions and uses
US6552033B1 (en) 2000-05-16 2003-04-22 The Procter & Gamble Co. Imidazo-containing heterocyclic compounds, their compositions and uses
US6596739B2 (en) 2000-03-29 2003-07-22 The Procter & Gamble Company N-(1-phenylethyl)-5-phenyl-imidazole-2-amine compounds, their compositions and uses
US7326792B2 (en) 2003-07-21 2008-02-05 Aventis Pharmaceuticals Inc. Heterocyclic compounds as P2X7 ion channel blockers
EP2513064B1 (en) * 2009-12-17 2018-07-04 Katholieke Universiteit Leuven, K.U. Leuven R&D Compounds, compositions and methods for controlling biofilms

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001044203A1 (en) * 1999-12-17 2001-06-21 The Procter & Gamble Company N-(1-phenylethyl)-5-phenyl-imidazole-2-amine compounds, their compositions and uses
US6596739B2 (en) 2000-03-29 2003-07-22 The Procter & Gamble Company N-(1-phenylethyl)-5-phenyl-imidazole-2-amine compounds, their compositions and uses
US6552033B1 (en) 2000-05-16 2003-04-22 The Procter & Gamble Co. Imidazo-containing heterocyclic compounds, their compositions and uses
US7326792B2 (en) 2003-07-21 2008-02-05 Aventis Pharmaceuticals Inc. Heterocyclic compounds as P2X7 ion channel blockers
US7741493B2 (en) 2003-07-21 2010-06-22 Aventis Pharmaceuticals Inc. Heterocyclic compounds as P2X7 ion channel blockers
EP2513064B1 (en) * 2009-12-17 2018-07-04 Katholieke Universiteit Leuven, K.U. Leuven R&D Compounds, compositions and methods for controlling biofilms

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