JPS536487A - Purification of hortimycin a - Google Patents

Purification of hortimycin a

Info

Publication number
JPS536487A
JPS536487A JP7885076A JP7885076A JPS536487A JP S536487 A JPS536487 A JP S536487A JP 7885076 A JP7885076 A JP 7885076A JP 7885076 A JP7885076 A JP 7885076A JP S536487 A JPS536487 A JP S536487A
Authority
JP
Japan
Prior art keywords
hortimycin
purification
impurities
chromatography
separate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP7885076A
Other languages
Japanese (ja)
Other versions
JPS597318B2 (en
Inventor
Shinzo Ishii
Toshio Tadano
Takashi Nara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP7885076A priority Critical patent/JPS597318B2/en
Priority to MX10071977U priority patent/MX4552E/en
Priority to CA281,947A priority patent/CA1074789A/en
Priority to GB2781177A priority patent/GB1587932A/en
Priority to AR26831777A priority patent/AR213118A1/en
Priority to AU26772/77A priority patent/AU511015B2/en
Priority to PH19948A priority patent/PH13988A/en
Priority to GR53885A priority patent/GR63243B/en
Priority to NL7707436A priority patent/NL7707436A/en
Priority to BE179111A priority patent/BE856509A/en
Publication of JPS536487A publication Critical patent/JPS536487A/en
Publication of JPS597318B2 publication Critical patent/JPS597318B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

PURPOSE: To separate hortimycin A from the solution of hortimycin A containing hortimycin B, C, etc. as impurities, by the chromatography using cationic ion exchange resin.
COPYRIGHT: (C)1978,JPO&Japio
JP7885076A 1976-07-05 1976-07-05 Purification method for hortimycin A Expired JPS597318B2 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
JP7885076A JPS597318B2 (en) 1976-07-05 1976-07-05 Purification method for hortimycin A
MX10071977U MX4552E (en) 1976-07-05 1977-06-22 PROCEDURE TO PURIFY FORTIMICIN A
CA281,947A CA1074789A (en) 1976-07-05 1977-07-04 Process for purifying fortimicin a
GB2781177A GB1587932A (en) 1976-07-05 1977-07-04 Process for purifying fortimicin a
AR26831777A AR213118A1 (en) 1976-07-05 1977-07-05 PROCEDURE TO ISOLATE FORTIMICIN A IN PURIFIED FORM FROM A SOLUTION CONTAINING IT MIXED WITH ANALOGUE ANTIBIOTIC COFACTORS
AU26772/77A AU511015B2 (en) 1976-07-05 1977-07-05 Purifying fortimicin a
PH19948A PH13988A (en) 1976-07-05 1977-07-05 Process for purifying portimicin a
GR53885A GR63243B (en) 1976-07-05 1977-07-05 Process for purifying fortimicin a
NL7707436A NL7707436A (en) 1976-07-05 1977-07-05 PROCESS FOR PURIFYING FORTIMICIN A.
BE179111A BE856509A (en) 1976-07-05 1977-07-05 FORTIMICIN A PURIFICATION PROCESS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7885076A JPS597318B2 (en) 1976-07-05 1976-07-05 Purification method for hortimycin A

Publications (2)

Publication Number Publication Date
JPS536487A true JPS536487A (en) 1978-01-20
JPS597318B2 JPS597318B2 (en) 1984-02-17

Family

ID=13673290

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7885076A Expired JPS597318B2 (en) 1976-07-05 1976-07-05 Purification method for hortimycin A

Country Status (10)

Country Link
JP (1) JPS597318B2 (en)
AR (1) AR213118A1 (en)
AU (1) AU511015B2 (en)
BE (1) BE856509A (en)
CA (1) CA1074789A (en)
GB (1) GB1587932A (en)
GR (1) GR63243B (en)
MX (1) MX4552E (en)
NL (1) NL7707436A (en)
PH (1) PH13988A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5721400A (en) * 1980-07-12 1982-02-04 Kyowa Hakko Kogyo Co Ltd Novel fortimicin derivative

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5721400A (en) * 1980-07-12 1982-02-04 Kyowa Hakko Kogyo Co Ltd Novel fortimicin derivative
JPS6328075B2 (en) * 1980-07-12 1988-06-07 Kyowa Hakko Kogyo Kk

Also Published As

Publication number Publication date
JPS597318B2 (en) 1984-02-17
AU511015B2 (en) 1980-07-24
GB1587932A (en) 1981-04-15
CA1074789A (en) 1980-04-01
GR63243B (en) 1979-10-12
PH13988A (en) 1980-11-28
MX4552E (en) 1982-06-10
AU2677277A (en) 1979-01-11
AR213118A1 (en) 1978-12-15
NL7707436A (en) 1978-01-09
BE856509A (en) 1978-01-05

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