JPS5277060A - Basic substituted indole derivatives and preparation thereof - Google Patents
Basic substituted indole derivatives and preparation thereofInfo
- Publication number
- JPS5277060A JPS5277060A JP51151501A JP15150176A JPS5277060A JP S5277060 A JPS5277060 A JP S5277060A JP 51151501 A JP51151501 A JP 51151501A JP 15150176 A JP15150176 A JP 15150176A JP S5277060 A JPS5277060 A JP S5277060A
- Authority
- JP
- Japan
- Prior art keywords
- preparation
- indole derivatives
- substituted indole
- basic substituted
- basic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19752557342 DE2557342A1 (en) | 1975-12-19 | 1975-12-19 | BASIC SUBSTITUTED INDOLDER DERIVATIVES AND THE PROCESS FOR THEIR PRODUCTION |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5277060A true JPS5277060A (en) | 1977-06-29 |
Family
ID=5964905
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP51151501A Pending JPS5277060A (en) | 1975-12-19 | 1976-12-18 | Basic substituted indole derivatives and preparation thereof |
Country Status (11)
Country | Link |
---|---|
JP (1) | JPS5277060A (en) |
AT (1) | ATA936276A (en) |
BE (1) | BE849626A (en) |
CA (1) | CA1079739A (en) |
DE (1) | DE2557342A1 (en) |
DK (1) | DK571376A (en) |
FR (1) | FR2335216A1 (en) |
GB (1) | GB1566307A (en) |
IT (1) | IT1065683B (en) |
LU (1) | LU76427A1 (en) |
NL (1) | NL7614050A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2009502859A (en) * | 2005-07-29 | 2009-01-29 | エフ.ホフマン−ラ ロシュ アーゲー | Indol-3-yl-carbonyl-piperidine and piperazine derivatives |
JP2010535816A (en) * | 2007-08-10 | 2010-11-25 | ハー・ルンドベック・アクチエゼルスカベット | Heteroaryl amide analogues |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5936675A (en) * | 1982-07-13 | 1984-02-28 | サンド・アクチエンゲゼルシヤフト | Cyclic carboxylic acid piperidyl ester and amide derivative |
US4476307A (en) * | 1982-09-20 | 1984-10-09 | Pfizer Inc. | Heteroylidene indolone compounds |
US4977178A (en) * | 1982-09-20 | 1990-12-11 | Pfizer Inc. | Method of treating anxiety and depression with 1-phenyl-2(1H,3H)-indolone psycho-therapeutic agents |
US4861880A (en) * | 1982-09-20 | 1989-08-29 | Pfizer Inc. | 1-phenyl-2(1H,3H)-indolone psycho-therapeutic agents |
US4879391A (en) * | 1982-09-20 | 1989-11-07 | Pfizer Inc. | 1-Phenyl-2(1H,3H)-indolone psychotherapeutic agents |
JPS6084281A (en) * | 1983-09-14 | 1985-05-13 | Yoshitomi Pharmaceut Ind Ltd | 3-indolecarboxamide |
DE3445377A1 (en) * | 1983-12-23 | 1985-07-04 | Sandoz-Patent-GmbH, 7850 Lörrach | CARBOCYLIC AND HETEROCYCLIC CARBONIC ACID ESTERS AND AMIDES OF BRIDGED AND NON-BRIDGED CYCLIC NITROCYLINE AMINES OR ALCOHOLS |
US5852014A (en) * | 1992-03-12 | 1998-12-22 | Smithkline Beecham P.L.C. | Condensed indole derivatives as 5HT4 -receptor antagonists |
HU219121B (en) * | 1992-03-12 | 2001-02-28 | Smithkline Beecham Plc. | Condensed indole derivatives and process for their preparation and pharmaceutical compositions of 5-ht4-receptor antagonistic activity containing them |
PT802183E (en) * | 1996-04-19 | 2002-03-28 | American Home Prod | ESTROGENIC AGENTS |
US6069153A (en) * | 1998-05-12 | 2000-05-30 | American Home Products Corporation | Indenoindoles and benzocarbazoles as estrogenic agents |
US6479535B1 (en) | 1998-05-15 | 2002-11-12 | Wyeth | 2-phenyl-1-[4-(2-aminoethoxy)-benzyl]-indole and estrogen formulations |
US6159959A (en) * | 1999-05-06 | 2000-12-12 | American Home Products Corporation | Combined estrogen and antiestrogen therapy |
PT1928454E (en) | 2005-05-10 | 2014-12-04 | Intermune Inc | Pyridone derivatives for modulating stress-activated protein kinase system |
CA2621720A1 (en) * | 2005-09-16 | 2007-03-29 | Serenex, Inc. | Carbazole derivatives |
JP5627574B2 (en) | 2008-06-03 | 2014-11-19 | インターミューン, インコーポレイテッド | Compounds and methods for treating inflammatory and fibrotic diseases |
AR092742A1 (en) | 2012-10-02 | 2015-04-29 | Intermune Inc | ANTIFIBROTIC PYRIDINONES |
CA2943363A1 (en) | 2014-04-02 | 2015-10-08 | Intermune, Inc. | Anti-fibrotic pyridinones |
-
1975
- 1975-12-19 DE DE19752557342 patent/DE2557342A1/en not_active Withdrawn
-
1976
- 1976-12-17 DK DK571376A patent/DK571376A/en not_active Application Discontinuation
- 1976-12-17 CA CA268,139A patent/CA1079739A/en not_active Expired
- 1976-12-17 AT AT936276A patent/ATA936276A/en not_active Application Discontinuation
- 1976-12-17 NL NL7614050A patent/NL7614050A/en not_active Application Discontinuation
- 1976-12-17 IT IT30582/76A patent/IT1065683B/en active
- 1976-12-17 LU LU76427A patent/LU76427A1/xx unknown
- 1976-12-18 JP JP51151501A patent/JPS5277060A/en active Pending
- 1976-12-20 GB GB53124/76A patent/GB1566307A/en not_active Expired
- 1976-12-20 BE BE173447A patent/BE849626A/en unknown
- 1976-12-20 FR FR7638400A patent/FR2335216A1/en not_active Withdrawn
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2009502859A (en) * | 2005-07-29 | 2009-01-29 | エフ.ホフマン−ラ ロシュ アーゲー | Indol-3-yl-carbonyl-piperidine and piperazine derivatives |
JP2010535816A (en) * | 2007-08-10 | 2010-11-25 | ハー・ルンドベック・アクチエゼルスカベット | Heteroaryl amide analogues |
Also Published As
Publication number | Publication date |
---|---|
CA1079739A (en) | 1980-06-17 |
BE849626A (en) | 1977-06-20 |
GB1566307A (en) | 1980-04-30 |
NL7614050A (en) | 1977-06-21 |
FR2335216A1 (en) | 1977-07-15 |
LU76427A1 (en) | 1977-07-05 |
ATA936276A (en) | 1980-02-15 |
DK571376A (en) | 1977-06-20 |
DE2557342A1 (en) | 1977-06-30 |
IT1065683B (en) | 1985-03-04 |
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