JPS5221389A - Process for preparing urokinase - Google Patents

Process for preparing urokinase

Info

Publication number
JPS5221389A
JPS5221389A JP9840875A JP9840875A JPS5221389A JP S5221389 A JPS5221389 A JP S5221389A JP 9840875 A JP9840875 A JP 9840875A JP 9840875 A JP9840875 A JP 9840875A JP S5221389 A JPS5221389 A JP S5221389A
Authority
JP
Japan
Prior art keywords
urokinase
preparing
preparing urokinase
thrombosis
remedy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP9840875A
Other languages
Japanese (ja)
Other versions
JPS5520675B2 (en
Inventor
Kenji Takesawa
Masaharu Nakanishi
Kozo Yumikari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Priority to JP9840875A priority Critical patent/JPS5221389A/en
Priority to FR7624680A priority patent/FR2320950A1/en
Priority to DE19762636478 priority patent/DE2636478A1/en
Publication of JPS5221389A publication Critical patent/JPS5221389A/en
Priority to US05/851,480 priority patent/US4169764A/en
Publication of JPS5520675B2 publication Critical patent/JPS5520675B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6462—Plasminogen activators u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21073—Serine endopeptidases (3.4.21) u-Plasminogen activator (3.4.21.73), i.e. urokinase

Abstract

PURPOSE: A process for preparing urokinase useful as a thrombosis remedy of high purity with high activity by the use of specific eluents.
COPYRIGHT: (C)1977,JPO&Japio
JP9840875A 1975-08-13 1975-08-13 Process for preparing urokinase Granted JPS5221389A (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP9840875A JPS5221389A (en) 1975-08-13 1975-08-13 Process for preparing urokinase
FR7624680A FR2320950A1 (en) 1975-08-13 1976-08-12 Urokinase chromatographic purificn. - using eluents contg. cationic surfactant
DE19762636478 DE2636478A1 (en) 1975-08-13 1976-08-13 PROCESS FOR THE OBTAINING UROKINASE
US05/851,480 US4169764A (en) 1975-08-13 1977-11-14 Process for production of urokinase

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9840875A JPS5221389A (en) 1975-08-13 1975-08-13 Process for preparing urokinase

Publications (2)

Publication Number Publication Date
JPS5221389A true JPS5221389A (en) 1977-02-17
JPS5520675B2 JPS5520675B2 (en) 1980-06-04

Family

ID=14218997

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9840875A Granted JPS5221389A (en) 1975-08-13 1975-08-13 Process for preparing urokinase

Country Status (3)

Country Link
JP (1) JPS5221389A (en)
DE (1) DE2636478A1 (en)
FR (1) FR2320950A1 (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5137343B2 (en) * 1972-12-07 1976-10-15

Also Published As

Publication number Publication date
DE2636478A1 (en) 1977-02-24
JPS5520675B2 (en) 1980-06-04
FR2320950A1 (en) 1977-03-11

Similar Documents

Publication Publication Date Title
JPS5213499A (en) Method for production of globule alumina support
JPS5244490A (en) Abrasion belt
JPS52248A (en) Process for preparing omega-aminoalkoxy biphenyls and their acid adducts
JPS5221389A (en) Process for preparing urokinase
JPS5276481A (en) Production of high purity urokinase
JPS51125356A (en) Process for preparing 4-hydroxycyclopent -2-ene-1-one
JPS5231818A (en) Process for manufacturing stable preparations of prostaglandin e
JPS51151393A (en) Process for preparing nojirimycin b
JPS51150871A (en) Process for the purificati on of sewage
JPS5219616A (en) Process for preparation of amides
JPS525083A (en) Polishing ring
JPS51149210A (en) Process for preparation of tetrafluoroethylene oligomers
JPS5212107A (en) Process for preparation of farnesol or its 10,11-isopropylidenedioxy d erivative
JPS51139688A (en) Process for preparing new alkaloid tm-64 substance by fermentation
JPS51144790A (en) Process for preparing l-cysteine derivatives
JPS51123887A (en) Method for preparing l-cysteine
JPS5257156A (en) Process for preparing 5,6_trans-24-hydroxycholecalciferol
JPS5223086A (en) Novel method of preparing 2,3- dioxopiperazine
JPS51151386A (en) Process for preparing glucomannase
JPS5239665A (en) Process for preparing perfluorolactones
JPS5352692A (en) Preparation of antibiotics colistine
JPS51120994A (en) Method for production of tungsten chloride
JPS5218881A (en) Method for preparing aspartase with high activity
JPS5223007A (en) Process for preparation of 1,1-dihalo-4, 4-dimethylbutadiene
JPS51135627A (en) Magnetic head