JPS52156869A - Production of benzomorphane derivatives and medical composition containing same - Google Patents

Production of benzomorphane derivatives and medical composition containing same

Info

Publication number
JPS52156869A
JPS52156869A JP7292177A JP7292177A JPS52156869A JP S52156869 A JPS52156869 A JP S52156869A JP 7292177 A JP7292177 A JP 7292177A JP 7292177 A JP7292177 A JP 7292177A JP S52156869 A JPS52156869 A JP S52156869A
Authority
JP
Japan
Prior art keywords
production
composition containing
medical composition
containing same
benzomorphane derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP7292177A
Other languages
English (en)
Inventor
Marii Akeruman Antonii
Karorusu Katarina B Herumanasu
Gerarudeina Ban Bu Henrietsuto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ACF Chemiefarma NV
Original Assignee
ACF Chemiefarma NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ACF Chemiefarma NV filed Critical ACF Chemiefarma NV
Publication of JPS52156869A publication Critical patent/JPS52156869A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
JP7292177A 1976-06-21 1977-06-21 Production of benzomorphane derivatives and medical composition containing same Pending JPS52156869A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB25577/76A GB1575009A (en) 1976-06-21 1976-06-21 6,7-benzomorphan derivatives

Publications (1)

Publication Number Publication Date
JPS52156869A true JPS52156869A (en) 1977-12-27

Family

ID=10229936

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7292177A Pending JPS52156869A (en) 1976-06-21 1977-06-21 Production of benzomorphane derivatives and medical composition containing same

Country Status (11)

Country Link
US (2) US4234591A (ja)
JP (1) JPS52156869A (ja)
BE (1) BE855938A (ja)
CH (1) CH634562A5 (ja)
DE (1) DE2726836A1 (ja)
DK (1) DK270077A (ja)
FR (1) FR2355830A1 (ja)
GB (1) GB1575009A (ja)
IE (1) IE44938B1 (ja)
LU (1) LU77585A1 (ja)
NL (1) NL7706328A (ja)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002537393A (ja) * 1999-02-23 2002-11-05 ベーリンガー インゲルハイム ファルマ コマンディトゲゼルシャフト 置換１，２，３，４，５，６−ヘキサヒドロ−２，６−メタノ−３−ベンゾアゾシン−１０−オール、その製造方法及び薬物としてのその使用
JP2015536972A (ja) * 2012-11-09 2015-12-24 パーデュー、ファーマ、リミテッド、パートナーシップ ベンゾモルファン類似体およびその使用

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2460298A1 (fr) * 1979-06-28 1981-01-23 Sterling Drug Inc Procede de preparation de 2,6-methano-3-benzazocines
US7501433B2 (en) * 2002-05-17 2009-03-10 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
JP5438250B2 (ja) 2002-05-17 2014-03-12 ジェンケン バイオサイエンスィズ，インコーポレイテッド オピオイド及びオピオイド様の化合物並びにそれらの使用
US7923454B2 (en) * 2002-05-17 2011-04-12 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
US8017622B2 (en) 2003-05-16 2011-09-13 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
EP2951160B1 (en) * 2013-01-31 2019-04-24 Purdue Pharma LP Benzomorphan analogs and the use thereof
US9975854B2 (en) * 2014-05-06 2018-05-22 Purdue Pharma L.P. Benzomorphan analogs and use thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3876644A (en) * 1965-06-25 1975-04-08 Bayer Ag Process for the production of 6,7-benzomorphanes

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE582575A (ja) * 1958-09-22
GB1050227A (ja) * 1963-11-07
US3639407A (en) * 1965-05-05 1972-02-01 Geigy Chem Corp Novel 1 2 3 4 5 6-hexahydro-6-phenyl-2 6-methano-3-benzazocines
US3499906A (en) * 1966-05-20 1970-03-10 Merck & Co Inc 5,9-diethyl-2'-hydroxy-2-substituted-6,7-benzomorphans
SE394277B (sv) * 1967-06-07 1977-06-20 Sumitomo Chemical Co Forfarande for framstellning av 6,7-bensomorfanderivat
US3553223A (en) * 1968-01-05 1971-01-05 Hoffmann La Roche Acid catalyzed cyclization of tetrahydropyridines containing an electron withdrawing group on the nitrogen
US3639410A (en) * 1968-07-26 1972-02-01 Sterling Drug Inc 1 2 3 4 5 6 - hexahydro - 8 - substituted-6-alkyl-11-(h or a lkyl) - 26-methano-3-benzazocines
US3511846A (en) * 1968-12-16 1970-05-12 Geigy Chem Corp Process for the preparation of optically active benzazocines
BR6914879D0 (pt) * 1969-01-23 1973-02-08 Merck & Co Inc Processos quimicos
CS166801B2 (ja) * 1971-02-08 1976-03-29 Boehringer Sohn Ingelheim
DE2217420C3 (de) * 1972-04-12 1981-03-12 C.H. Boehringer Sohn, 6507 Ingelheim N-Thienylmethyl-Heterocyclen, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zubereitungen
DE2229695A1 (de) * 1972-06-19 1974-01-31 Boehringer Sohn Ingelheim 2-(heteroaryl-methyl)-5,9 beta-dialkyl6,7-benzomorphane, deren saeureadditionssalze sowie verfahren zu deren herstellung
US4087532A (en) * 1974-03-09 1978-05-02 Boehringer Ingelheim Gmbh Analgesically useful 2-tetrahydrofurfuryl-5-lower alkyl-2-oxy-6,7-benzomorphans and salts thereof
US3932422A (en) * 1974-05-20 1976-01-13 Sterling Drug Inc. 8-Methylene-3-azabicyclo[3.3.1]non-6-en-4-ones
DE2437610A1 (de) * 1974-08-05 1976-02-26 Boehringer Sohn Ingelheim Neue 5,9-beta-disubstituierte 2-tetrahydrofurfuryl-6,7-benzomorphane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung
US4108857A (en) * 1975-08-18 1978-08-22 Sterling Drug Inc. Imidazolylmethyl methanobenzazocines
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3876644A (en) * 1965-06-25 1975-04-08 Bayer Ag Process for the production of 6,7-benzomorphanes

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002537393A (ja) * 1999-02-23 2002-11-05 ベーリンガー インゲルハイム ファルマ コマンディトゲゼルシャフト 置換１，２，３，４，５，６−ヘキサヒドロ−２，６−メタノ−３−ベンゾアゾシン−１０−オール、その製造方法及び薬物としてのその使用
JP2015536972A (ja) * 2012-11-09 2015-12-24 パーデュー、ファーマ、リミテッド、パートナーシップ ベンゾモルファン類似体およびその使用

Also Published As

Publication number Publication date
CH634562A5 (de) 1983-02-15
FR2355830A1 (fr) 1978-01-20
IE44938L (en) 1977-12-21
DE2726836A1 (de) 1977-12-29
FR2355830B1 (ja) 1981-04-30
LU77585A1 (ja) 1977-09-29
BE855938A (nl) 1977-12-21
IE44938B1 (en) 1982-05-19
GB1575009A (en) 1980-09-17
NL7706328A (nl) 1977-12-23
DK270077A (da) 1977-12-22
US4234591A (en) 1980-11-18
US4288444A (en) 1981-09-08

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