JPH1157043A - Neutron-irradiation apparatus for treatment and method therefor - Google Patents
Neutron-irradiation apparatus for treatment and method thereforInfo
- Publication number
- JPH1157043A JPH1157043A JP22491497A JP22491497A JPH1157043A JP H1157043 A JPH1157043 A JP H1157043A JP 22491497 A JP22491497 A JP 22491497A JP 22491497 A JP22491497 A JP 22491497A JP H1157043 A JPH1157043 A JP H1157043A
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- Japan
- Prior art keywords
- neutrons
- target
- accelerated
- accelerator
- directions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- Particle Accelerators (AREA)
- Radiation-Therapy Devices (AREA)
Abstract
Description
【０００１】[0001]
【発明の属する技術分野】本発明は、患部に中性子線を
照射する装置及び方法に関し、特に加速器を使用する中
性子捕捉治療装置に関する。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an apparatus and a method for irradiating an affected part with neutron rays, and more particularly to a neutron capture therapy apparatus using an accelerator.
【０００２】[0002]
【従来の技術】図２に粒子加速器を使用した従来の中性
子捕捉治療装置の概念図を示す。この装置では、中性子
の発生に陽子の線形加速器１を用いていて、真空ポンプ
３に連絡した真空導管５の中を加速陽子が偏向磁石７及
び集束磁石９によって導かれてターゲット１１に当てら
れる。ターゲット１１は、例えばリチウムLiのようなも
ので、（ｐ，ｎ）反応により中性子ｎ、即ち高速中性子
を発生する（７Li（ｐ，ｎ）７Be）。この高速中性子
は、中性子フィルタ（減速材）１３により治療に適した
エネルギーレベル（熱中性子、熱外中性子）に減速され
た後、コリメータ１５により絞られて照射室１７内の患
者１９の患部に照射される。ターゲット１１、中性子フ
ィルタ１３及びコリメータ１５は、照射室１７と加速器
室とを隔てる遮蔽コンクリート壁１６の中に設けられて
いて、照射場の中性子強度は、ターゲット１１の核反応
量によって決まり、これは加速陽子の量即ち線形加速器
１の電流値によって定まる。2. Description of the Related Art FIG. 2 shows a conceptual diagram of a conventional neutron capture and treatment apparatus using a particle accelerator. In this device, a proton linear accelerator 1 is used to generate neutrons, and accelerated protons are guided by a deflection magnet 7 and a focusing magnet 9 to a target 11 in a vacuum conduit 5 connected to a vacuum pump 3. The target 11 is, for example, lithium Li and generates neutrons n, that is, fast neutrons (7Li (p, n) 7Be) by the (p, n) reaction. The fast neutrons are decelerated to an energy level (thermal neutrons, epithermal neutrons) suitable for the treatment by a neutron filter (moderator) 13 and then squeezed by a collimator 15 to irradiate the affected part of the patient 19 in the irradiation chamber 17. Is done. The target 11, the neutron filter 13 and the collimator 15 are provided in a shielded concrete wall 16 separating the irradiation room 17 and the accelerator room, and the neutron intensity of the irradiation field is determined by the nuclear reaction amount of the target 11, and It is determined by the amount of accelerating protons, that is, the current value of the linear accelerator 1.
【０００３】[0003]
【発明が解決しようとする課題】上述の中性子捕捉治療
装置においては、中性子の生成に原子炉のような大型の
設備を用いず、更に中性子強度を容易に調整できて治療
に便利であるが、次のような解決すべき問題点を有して
いる。即ち、 （１）陽子のような荷電粒子（電流値）を増やすと、タ
ーゲットの核反応による発熱量が増えて、ターゲットの
冷却が難しくなる。このためターゲットの材料の選択や
冷却構造の選定に制約が多くなる。 （２）一方向からの照射では、患部に至る体内での中性
子減衰効果により患部での中性子照射量が一様になりに
くく、適切な治療効果の実現に難がある。従って、本発
明は、ターゲットにおける発熱量が少なく、且つ患部に
おける中性子照射量が一様になるような治療用中性子照
射装置及び照射方法を提供することを課題とする。The neutron capture and treatment apparatus described above is convenient for treatment because neutrons can be generated without using large-scale equipment such as a nuclear reactor and the neutron intensity can be easily adjusted. It has the following problems to be solved. That is, (1) When the number of charged particles (current value) such as protons is increased, the amount of heat generated by the nuclear reaction of the target increases, and cooling of the target becomes difficult. Therefore, there are many restrictions on the selection of the target material and the selection of the cooling structure. (2) In irradiation from one direction, it is difficult for the neutron irradiation amount in the affected part to be uniform due to the neutron attenuation effect in the body to the affected part, and it is difficult to realize an appropriate therapeutic effect. Accordingly, an object of the present invention is to provide a therapeutic neutron irradiation apparatus and an irradiation method in which the amount of heat generated in a target is small and the neutron irradiation amount in an affected area is uniform.
【０００４】[0004]
【課題を解決するための手段】如上の課題を解決するた
め、本発明によれば、治療用中性子照射装置は、荷電粒
子の加速器と、同加速器から出る加速荷電粒子流を複数
方向流に分割する荷電粒子流分割装置と、遮蔽壁体の中
に設けられ、加速荷電粒子が衝撃されて高速中性子を発
生するターゲットと、前記荷電粒子流分割装置から前記
ターゲットの各に加速荷電粒子流を導く分岐導管と、前
記遮蔽壁体内に設けられその遮蔽壁体に囲まれた室内の
治療台上に中性子を集束指向するコリメータと、前記タ
ーゲット及び前記コリメータの間に介装され前記高速中
性子を治療に適したレベルに減速する中性子フィルタと
を有して構成される。更に本発明によれば、治療用中性
子の照射方法は、加速器で荷電粒子を加速し、加速荷電
粒子の流れを複数方向流に分割し、該複数方向流の加速
荷電粒子をそれぞれ対応のターゲットに当てて核反応に
より高速中性子を発生させ、その高速中性子を治療適性
レベルに調整したのち、被治療者の患部に複数方向から
レベル調整中性子を照射する各ステップから構成され
る。According to the present invention, in order to solve the above problems, a therapeutic neutron irradiation apparatus divides a charged particle accelerator and an accelerated charged particle flow exiting the accelerator into a plurality of directions. A charged particle flow splitting device, a target provided in a shielding wall, and a target in which accelerated charged particles are bombarded to generate fast neutrons, and guiding the accelerated charged particle flow from the charged particle flow splitting device to each of the targets. A branching conduit, a collimator provided in the shielding wall body, for focusing and directing neutrons on a treatment table in a room surrounded by the shielding wall body, and interposed between the target and the collimator for treating the fast neutrons. And a neutron filter for decelerating to a suitable level. Further according to the present invention, the method of irradiating therapeutic neutrons accelerates the charged particles with an accelerator, divides the flow of the accelerated charged particles into a plurality of directional flows, and applies the accelerated charged particles of the multidirectional flows to corresponding targets. The method comprises the steps of generating fast neutrons by applying a nuclear reaction, adjusting the fast neutrons to a therapeutic suitability level, and irradiating the affected part of the patient with level-adjusted neutrons from a plurality of directions.
【０００５】[0005]
【発明の実施の形態】以下、添付の図面を参照して、本
発明を実施形態について説明する。尚、前述した従来技
術に関する図面を含む全図面に亙り、同一部分には同一
の符号を付すこととする。先ず図１を参照するに、荷電
粒子の加速器即ち陽子の線形加速器１の陽子出口から真
空導管２１が延出し、曲がり部の周囲に偏向磁石７が設
けられている。真空導管２１は、分岐導管２３ａ，２３
ｂに分かれるが、その分岐点の直前の周囲に振り分け磁
石２５が２個分離して設けられている。一方、遮蔽コン
クリート壁２７の中に中性子フィルタである減速材２９
が設けられていて、その加速器室側にそれぞれターゲッ
ト３１が設けられている。前述の分岐導管２３ａ，２３
ｂは、それぞれ対応のターゲット３１まで延びている
が、湾曲部を有する分岐導管２３ｂには、偏向磁石３３
が設けられて加速陽子の流れを導いている。尚、配設さ
れるターゲットの数及び位置は、前述以外に種々のもの
が考えられ、これに応じて分岐導管の数及び形状が変化
することを理解すべきである。更に、遮蔽コンクリート
壁２７内において減速材２９の照射室側には、コリメー
タ３５が設けられ、治療台１８上の患者１９の体内に形
成された照射場３７に指向している。照射場３７は、体
内に注入された10Ｂが患部に集まって形成されている。Embodiments of the present invention will be described below with reference to the accompanying drawings. Note that the same reference numerals are given to the same portions throughout all the drawings including the drawings related to the above-described prior art. Referring first to FIG. 1, a vacuum conduit 21 extends from a proton outlet of a charged particle accelerator, ie, a proton linear accelerator 1, and a bending magnet 7 is provided around a bend. The vacuum conduit 21 includes branch conduits 23a, 23
b, two distributing magnets 25 are separately provided around immediately before the branch point. On the other hand, a moderator 29 which is a neutron filter is provided in the shielding concrete wall 27.
Are provided, and targets 31 are provided on the accelerator room side, respectively. The aforementioned branch conduits 23a, 23
b extend to the corresponding target 31, respectively.
Are provided to guide the flow of accelerated protons. It should be understood that the number and the position of the targets to be provided may be various other than the above, and the number and the shape of the branch conduits may be changed accordingly. Further, a collimator 35 is provided on the irradiation room side of the moderator 29 in the shielding concrete wall 27 and is directed to an irradiation field 37 formed in the body of the patient 19 on the treatment table 18. The irradiation field 37 is formed by collecting 10 B injected into the body at the affected part.
【０００６】以上のような構成の中性子照射装置２０に
おいて、線形加速器１で加速された多数の陽子ｐは、陽
子流となって真空導管２１の中を偏向磁石７の作用を受
けて進み、振り分け磁石２５により適当な割合例えば
５：５で分岐導管２３ａ，２３ｂに振り分けられる。こ
のように分岐された陽子流は、集束磁石９によりそれぞ
れターゲット３１に衝撃されて、（ｐ，ｎ）反応により
高速中性子を発生する。この高速中性子は減速材２９に
より例えば熱中性子レベルまで減速されたのち、その熱
中性子はコリメータ３５により集束されて患者１９の体
内の照射場３７に２方向から照射される。10Ｂは、
（ｎ，α）反応によりアルファ線を出して患部の治療を
行う。尚、上述の実施形態では、粒子加速器として線形
加速器を使用し、粒子として陽子を加速したが、他の形
式の加速器を使用しても良いことは勿論である。In the neutron irradiation apparatus 20 having the above-described configuration, a large number of protons p accelerated by the linear accelerator 1 travel as a proton flow in the vacuum conduit 21 under the action of the deflecting magnet 7 and are distributed. The magnets 25 are distributed to the branch conduits 23a and 23b at an appropriate ratio, for example, 5: 5. The proton flows branched in this manner are impacted by the focusing magnets 9 on the targets 31, respectively, and fast neutrons are generated by the (p, n) reaction. After the fast neutrons are decelerated by the moderator 29 to, for example, the thermal neutron level, the thermal neutrons are focused by the collimator 35 and irradiated onto the irradiation field 37 in the patient 19 from two directions. 10 B is
The affected part is treated by emitting alpha rays by the (n, α) reaction. In the above-described embodiment, the linear accelerator is used as the particle accelerator and the protons are accelerated as particles. However, it is needless to say that another type of accelerator may be used.
【０００７】[0007]
【発明の効果】前述したように、本発明によれば、粒子
加速器から出た加速粒子は、分岐してターゲットに衝撃
されるので、個別のターゲットにおける核反応量が小さ
くなって発熱が抑えられる。更に、被治療者の患部に
は、複数の方向から最適な比率で中性子が照射されるの
で、患部の中性子強度分布を一様にでき、治療効果を向
上することができる。As described above, according to the present invention, accelerating particles emitted from the particle accelerator branch off and are impacted by the target, so that the amount of nuclear reaction in each individual target is reduced and heat generation is suppressed. . Further, since the neutrons are irradiated to the affected part of the patient at an optimal ratio from a plurality of directions, the neutron intensity distribution of the affected part can be made uniform, and the treatment effect can be improved.
【図１】本発明に係る実施形態の全体構成を示す概念図
である。FIG. 1 is a conceptual diagram showing an overall configuration of an embodiment according to the present invention.
【図２】従来装置の構造の一例を示す概念図である。FIG. 2 is a conceptual diagram showing an example of the structure of a conventional device.
１ 線形加速器 ７ 偏向磁石 ９ 集束磁石 １７ 照射室 １８ 治療台 １９ 患者（被治療者） ２０ 中性子照射装置 ２３ 真空導管 ２３ａ，２３ｂ 分岐導管 ２５ 振り分け磁石 ２７ 遮蔽コンクリート壁 ２９ 減速材 ３１ ターゲット ３３ 偏向磁石 ３５ コリメータ ３７ 照射場 DESCRIPTION OF SYMBOLS 1 Linear accelerator 7 Deflection magnet 9 Focusing magnet 17 Irradiation room 18 Treatment table 19 Patient (patient) 20 Neutron irradiation device 23 Vacuum conduit 23a, 23b Branch conduit 25 Distribution magnet 27 Shielding concrete wall 29 Moderator 31 Target 33 Deflecting magnet 35 Collimator 37 Irradiation field
Claims (2)
加速荷電粒子流を複数方向流に分割する荷電粒子流分割
装置と、遮蔽壁体の中に設けられ、加速荷電粒子を衝撃
させて高速中性子を発生するターゲットと、前記荷電粒
子流分割装置から前記ターゲットの各に加速荷電粒子流
を導く分岐導管と、前記遮蔽壁体内に設けられ同遮蔽壁
体に囲まれた室内の治療台上に中性子を集束指向するコ
リメータと、前記ターゲット及び前記コリメータの間に
介装され前記高速中性子を治療に適したレベルに調整す
る中性子フィルタとを有することを特徴とする治療用中
性子照射装置。1. A charged particle accelerator, a charged particle flow splitting device for splitting an accelerated charged particle flow exiting the accelerator into a plurality of directional flows, and provided in a shielding wall, wherein the accelerated charged particles are bombarded to accelerate the charged particle flow. A target for generating neutrons, a branch conduit for guiding an accelerated charged particle stream from the charged particle stream splitting device to each of the targets, and a treatment table in a room provided in the shield wall and surrounded by the shield wall. A therapeutic neutron irradiation apparatus comprising: a collimator for focusing and directing neutrons; and a neutron filter interposed between the target and the collimator to adjust the high-speed neutrons to a level suitable for treatment.
子の流れを複数方向流に分割し、該複数方向流の加速荷
電粒子をそれぞれ対応のターゲットに当てて核反応によ
り高速中性子を発生させ、その高速中性子を治療適性レ
ベルに減速した後、被治療者の患部に複数方向からレベ
ル調整中性子を照射することを特徴とする治療用中性子
の照射方法。2. The charged particles are accelerated by an accelerator, the flow of the accelerated charged particles is divided into a plurality of directions, and the accelerated charged particles in the plurality of directions are respectively applied to corresponding targets to generate fast neutrons by a nuclear reaction. And irradiating the affected part of the patient with level-adjusting neutrons from a plurality of directions after decelerating the fast neutrons to a treatment-suitable level.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP22491497A JPH1157043A (en) | 1997-08-21 | 1997-08-21 | Neutron-irradiation apparatus for treatment and method therefor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP22491497A JPH1157043A (en) | 1997-08-21 | 1997-08-21 | Neutron-irradiation apparatus for treatment and method therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH1157043A true JPH1157043A (en) | 1999-03-02 |
Family
ID=16821148
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP22491497A Withdrawn JPH1157043A (en) | 1997-08-21 | 1997-08-21 | Neutron-irradiation apparatus for treatment and method therefor |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH1157043A (en) |
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|---|---|---|---|---|
| JP2006047115A (en) * | 2004-08-04 | 2006-02-16 | Mitsubishi Heavy Ind Ltd | Neutron generating apparatus, target and neutron irradiation system |
| JP2007095553A (en) * | 2005-09-29 | 2007-04-12 | Hitachi Ltd | System using accelerator |
| JP2009204428A (en) * | 2008-02-27 | 2009-09-10 | Sumitomo Heavy Ind Ltd | Target recovery system |
| JP2010273785A (en) * | 2009-05-27 | 2010-12-09 | Mitsubishi Electric Corp | Particle beam therapy system |
| JP2013061295A (en) * | 2011-09-14 | 2013-04-04 | Sumitomo Heavy Ind Ltd | Neutron ray irradiation device |
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-
1997
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| JP2007095553A (en) * | 2005-09-29 | 2007-04-12 | Hitachi Ltd | System using accelerator |
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| JP2009204428A (en) * | 2008-02-27 | 2009-09-10 | Sumitomo Heavy Ind Ltd | Target recovery system |
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