JPH0899857A - Skin external agent - Google Patents
Skin external agentInfo
- Publication number
- JPH0899857A JPH0899857A JP6261079A JP26107994A JPH0899857A JP H0899857 A JPH0899857 A JP H0899857A JP 6261079 A JP6261079 A JP 6261079A JP 26107994 A JP26107994 A JP 26107994A JP H0899857 A JPH0899857 A JP H0899857A
- Authority
- JP
- Japan
- Prior art keywords
- skin
- external agent
- nut oil
- pine nut
- derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Description
【０００１】[0001]
【産業上の利用分野】本発明は、荒れ肌改善作用にすぐ
れる皮膚外用剤に関する。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a skin external preparation which is excellent in improving rough skin.
【０００２】[0002]
【従来技術および発明が解決しようとする課題】一般に
化粧品などの皮膚外用剤には各種界面活性剤が配合され
ている。これらの界面活性剤は程度の差はあるが皮膚や
粘膜に対し脱脂作用、ケラチンタンパク質の変性作用な
どの作用を有し、結果として皮膚の乾燥とバリア機能の
低下を引き起こし、連用によっては肌荒れを誘発するこ
とが知られている。そこで、これらの作用の関与を抑制
するために温和な作用を持つ界面活性剤の開発が進めら
れ、更に界面活性剤の皮膚吸着性を抑制する様々な物質
の配合が提案されている。しかし、未だ満足される結果
は得られていないのが実情である。また、肌荒れを緩和
する目的で従来化粧品などの皮膚外用剤には、アミノ酸
などの保湿剤が配合されているが、これらは水溶性が高
いために日常生活の中で水にさらされた際には流出し、
皮膚への十分な残留が期待出来ず、保湿効果を発揮でき
ないという欠点を有している。スクワレンやトリグリセ
リドなどの脂質を保湿剤として洗浄剤等に配合して用い
る場合もあるが、洗浄力の低下をもたらし、洗浄剤自体
の安定性をも損なうという問題があった。さらに、モノ
グリセリドを配合した荒れ肌改善剤が提案されているが
（特開平６−１８３９４８号公報）、これについて検討
したところ少なくとも低濃度の配合では顕著な効果を示
さないことが判明した。したがって、皮膚への刺激や損
傷、特に洗浄剤等の使用に起因する肌荒れに大してすぐ
れた緩和、改善効果をする皮膚外用剤が望まれていた。2. Description of the Related Art Generally, various kinds of surfactants are incorporated into external preparations for skin such as cosmetics. To some extent, these surfactants have actions such as degreasing action on the skin and mucous membranes, denaturing action of keratin protein, etc., resulting in dryness of the skin and deterioration of barrier function. Known to trigger. Therefore, in order to suppress the involvement of these effects, the development of a surfactant having a mild effect has been advanced, and further, the incorporation of various substances that suppress the skin adsorption of the surfactant has been proposed. However, the actual situation is that satisfactory results have not yet been obtained. In addition, moisturizers such as amino acids have been conventionally mixed with skin external preparations such as cosmetics for the purpose of relieving rough skin, but since these are highly water-soluble, they can be exposed to water during daily life. Leaked,
It has the drawback that it cannot be expected to remain sufficiently on the skin and cannot exert its moisturizing effect. There are also cases where lipids such as squalene and triglyceride are used as a moisturizing agent by being mixed with a detergent or the like, but there is a problem in that the detergency is lowered and the stability of the detergent itself is impaired. Further, a rough skin improving agent containing a monoglyceride has been proposed (Japanese Patent Laid-Open No. 6-183948), but as a result of studying this, it was found that at least a low concentration of the compound does not show a remarkable effect. Therefore, there has been a demand for an external preparation for skin which is excellent in alleviating and improving the skin irritation and damage, especially the rough skin caused by the use of a detergent and the like.
【０００３】[0003]
【課題を解決するための手段】かかる実情において、本
発明者らは鋭意研究を行った結果、驚くべきことに、特
定のオイルを配合した皮膚外用剤がすぐれた肌荒れ改善
作用を有し、特に界面活性剤による皮膚刺激を抑制し、
肌荒れ緩和作用を有することを見出し、本発明を完成し
た。Under the circumstances, as a result of intensive studies conducted by the present inventors, surprisingly, a skin external preparation containing a specific oil has an excellent rough skin improving effect, Suppresses skin irritation caused by surfactants,
The present invention has been completed by finding that it has a rough skin alleviating effect.
【０００４】すなわち、本発明は松の実オイルを配合す
ることを特徴とする皮膚外用剤を提供するものである。That is, the present invention provides a skin external preparation characterized by containing pine nut oil.
【０００５】本発明において用いられる松の実オイル
は、例えば、松の実を低温ないし室温で圧搾し、有機溶
媒によって抽出した後，有機溶媒を減圧除去することに
よって容易に製造することができる。この場合得られる
松の実オイルは、高蛋白固形分とリノレン酸を含む油脂
を主に含有する。また、松の実の殻をアルカリ水溶液に
侵漬して、抽出処理をすることにより、松の実の水溶性
オイルを容易に製造することができ、これを配合した皮
膚外用剤はウイルス性皮膚病疾患患者にも有効である。The pine nut oil used in the present invention can be easily produced, for example, by squeezing pine nuts at a low temperature to room temperature, extracting with an organic solvent, and then removing the organic solvent under reduced pressure. The pine nut oil obtained in this case mainly contains fats and oils containing high protein solids and linolenic acid. By immersing the pine nut shell in an alkaline aqueous solution and subjecting it to an extraction treatment, a water-soluble oil of pine nuts can be easily produced. It is also effective for patients with diseases.
【０００６】本発明の皮膚外用剤には必要に応じて本発
明の効果を損なわない範囲でアラントイン、グリチルリ
チン酸及びグリチルレチン酸誘導体、ビタミンＥ誘導
体、ビタミンＣ誘導体、殺菌剤その他の有効成分を適宜
配合することができる。また、香料、色素、防腐剤、増
粘剤、保湿剤等の任意成分を配合することができる。本
発明の皮膚外用剤は、肌あれを生じた部位に直接塗布す
ることによって使用される。If necessary, allantoin, glycyrrhizinic acid and glycyrrhetinic acid derivatives, vitamin E derivatives, vitamin C derivatives, bactericides and other active ingredients are appropriately added to the external preparation for skin of the present invention as long as the effects of the present invention are not impaired. can do. Further, optional ingredients such as fragrances, pigments, preservatives, thickeners, moisturizers and the like can be added. The external preparation for skin of the present invention is used by directly applying it to the site where the skin is roughened.
【０００７】本発明の皮膚外用剤は、通常のクリーム
状、乳液状、ローション状の形態で、皮膚化粧料として
使用することができるばかりでなく、それ以外の形態、
例えば軟膏状で皮膚外用剤としても使用するすることが
できる。この場合、本発明の皮膚外用剤の組成物中に松
の実オイルを０．１％〜２０重量％、特に１〜１０重量
％配合することが好ましい。配合量が０．１重量％未満
であると十分な肌荒れ改善効果が得られず、また、２０
重量％を越えると著しく増粘して好ましくない場合があ
る。The external preparation for skin of the present invention can be used not only in the form of ordinary cream, emulsion or lotion as a skin cosmetic, but also in other forms.
For example, it can be used as an ointment in the form of an ointment. In this case, it is preferable to add pine nut oil to the composition of the external preparation for skin of the present invention in an amount of 0.1% to 20% by weight, particularly 1 to 10% by weight. If the blending amount is less than 0.1% by weight, a sufficient effect of improving rough skin cannot be obtained.
If it exceeds 5% by weight, the viscosity may remarkably increase, which may be undesirable.
【０００８】[0008]
【実施例】以下に実施例を挙げて本発明を更に説明する
が、本発明はこれらによって何ら限定されるものではな
い。なお、本実施例中で用いた試験方法は次の通りであ
る。The present invention will be further described below with reference to examples, but the present invention is not limited thereto. The test method used in this example is as follows.
【０００９】荒れ肌改善テスト 下脚部に荒れ肌を有する中高年被験者１０名を対象とし
て４週間連続塗布した後の効果を調べた。被験者の左側
下脚外側試験部位に一日一回約０．５ｇを塗布し、試験
開始前及び終了後の皮膚の状態を次の判定基準によって
判定した。右側下脚部は試料を塗布せずに対照とした。 試験前後の試験部位と対照部位の判定結果を比較し、皮
膚乾燥度が２段階以上改善された場合、（例えば、＋か
ら−）を有効、１段階改善された場合をやや有効、変化
がなかった場合を無効とした。試験結果は有効、やや有
効となった被験者の人数で示した。Rough skin improvement test Ten middle-aged and elderly subjects having rough skin on the lower legs were tested for their effects after continuous application for 4 weeks. About 0.5 g was applied once a day to the outer test site of the left lower leg of the test subject, and the skin condition before and after the start of the test was evaluated according to the following criteria. The lower right leg served as a control without applying the sample. By comparing the judgment results of the test site and the control site before and after the test, if the skin dryness is improved by two or more stages, (for example, from + to-) is effective, and if it is improved by one stage, it is slightly effective and there is no change. The case is invalid. The test results were shown by the number of subjects who were valid or slightly valid.
【００１０】製造例１（松の実オイル） 新鮮な松の実１ｋｇを粉砕し、アセトン５リットルに侵
漬後、松の実オイルを抽出し、松の実の残さをを除去し
た松の実オイルのアセトン溶液からアセトンを減圧除去
させて松の実オイル８５０ｇを得る。Production Example 1 (pine nut oil) 1 kg of fresh pine nuts was crushed and immersed in 5 liters of acetone, and then pine nut oil was extracted to remove the residue of pine nuts. Acetone solution was removed from the acetone under reduced pressure to obtain 850 g of pine nut oil.
【００１１】実施例１〜２、比較例１（クリーム状組成
物） 表１に示す配合組成のクリーム状組成物を下記方法によ
って調製した。 （製法）油相を７０〜８０℃に加熱し、攪拌により溶融
せしめこれに攪拌下７０〜８０℃に加熱溶解した水相を
添加して乳化を行い、５０℃まで冷却し香料を添加した
後、２０〜３０℃まで冷却する。次に、上記方法による
荒れ肌改善テストを行った。その結果を表１に示す。Examples 1 and 2, Comparative Example 1 (Cream-like composition) A cream-like composition having the composition shown in Table 1 was prepared by the following method. (Manufacturing method) The oil phase is heated to 70 to 80 ° C., melted by stirring, and the water phase heated and dissolved at 70 to 80 ° C. is added with stirring to emulsify the mixture. Cool to 20-30 ° C. Next, a rough skin improvement test was conducted by the above method. The results are shown in Table 1.
【００１２】[0012]
【表１】 [Table 1]
【００１３】表１に示す通り、本発明によるクリーム状
組成物は比較例のそれと比べて格段にすぐれた荒れ肌改
善効果を持つ。As shown in Table 1, the creamy composition according to the present invention has a markedly improved rough skin improving effect as compared with that of the comparative example.
【００１４】表２に示す配合組成のローション状組成物
を下記方法によって調製した。 （製法）Ｃ成分の松の実オイルはＢ成分に配合して、
Ａ、Ｂ成分を均一に溶解した後、Ａ成分とＢ成分を混合
攪拌分散し、次いで容器に充填する。使用前に振ってか
ら使用する。次に、これを用いて上記方法による荒れ肌
改善テストを行った。その結果を表２に示す。Lotion-like compositions having the composition shown in Table 2 were prepared by the following method. (Production method) C component pine nut oil is blended with B component,
After uniformly dissolving the components A and B, the components A and B are mixed and dispersed by stirring, and then filled in a container. Shake before use before use. Next, using this, a rough skin improvement test was conducted by the above method. The results are shown in Table 2.
【００１５】[0015]
【表２】 [Table 2]
【００１６】表２に示す通り、本発明によるローション
状組成物（実施例３、４）は比較例のそれと比べて格段
にすぐれた荒れ肌改善効果を持つ。As shown in Table 2, the lotion-like compositions according to the present invention (Examples 3 and 4) have markedly improved rough skin improving effect as compared with that of the comparative example.
【００１７】[0017]
【発明の効果】以上記載の通り、本発明は荒れ肌改善効
果の優れた皮膚外用剤を提供することができる。INDUSTRIAL APPLICABILITY As described above, the present invention can provide a skin external preparation having an excellent effect of improving rough skin.
Claims (1)
る皮膚外用剤。1. An external preparation for skin, which comprises pine nut oil.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6261079A JPH0899857A (en) | 1994-09-29 | 1994-09-29 | Skin external agent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6261079A JPH0899857A (en) | 1994-09-29 | 1994-09-29 | Skin external agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH0899857A true JPH0899857A (en) | 1996-04-16 |
Family
ID=17356795
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP6261079A Pending JPH0899857A (en) | 1994-09-29 | 1994-09-29 | Skin external agent |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH0899857A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004224742A (en) * | 2003-01-23 | 2004-08-12 | Umeken:Kk | Skin care preparation |
| JP2007063195A (en) * | 2005-08-31 | 2007-03-15 | Katakura Chikkarin Co Ltd | Bleaching agent and external preparation for skin containing the same |
| JP2009523785A (en) * | 2006-01-19 | 2009-06-25 | 株式會社アモーレパシフィック | Cosmetic composition containing Kaimatsuko extract as an active ingredient |
-
1994
- 1994-09-29 JP JP6261079A patent/JPH0899857A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004224742A (en) * | 2003-01-23 | 2004-08-12 | Umeken:Kk | Skin care preparation |
| JP2007063195A (en) * | 2005-08-31 | 2007-03-15 | Katakura Chikkarin Co Ltd | Bleaching agent and external preparation for skin containing the same |
| JP2009523785A (en) * | 2006-01-19 | 2009-06-25 | 株式會社アモーレパシフィック | Cosmetic composition containing Kaimatsuko extract as an active ingredient |
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