JPH0880352A - Medicinal liquid injecting appliance - Google Patents

Medicinal liquid injecting appliance

Info

Publication number
JPH0880352A
JPH0880352A JP6217682A JP21768294A JPH0880352A JP H0880352 A JPH0880352 A JP H0880352A JP 6217682 A JP6217682 A JP 6217682A JP 21768294 A JP21768294 A JP 21768294A JP H0880352 A JPH0880352 A JP H0880352A
Authority
JP
Japan
Prior art keywords
chemical liquid
medicinal liquid
cylindrical drum
balloon
drug solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6217682A
Other languages
Japanese (ja)
Inventor
Norihiro Hiejima
徳寛 比恵島
Takeichi Miyauchi
偉一 宮内
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nissho Corp
Original Assignee
Nissho Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissho Corp filed Critical Nissho Corp
Priority to JP6217682A priority Critical patent/JPH0880352A/en
Publication of JPH0880352A publication Critical patent/JPH0880352A/en
Pending legal-status Critical Current

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  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

PURPOSE: To make it possible to inject a medicinal liquid into the human body at a specified speed at all times by providing this appliance with a cylindrical drum spread with sheets expandable by medicinal liquid inflow on both sides of a barrel and a rotary disk of a cylindrical type which slides and rotates on the outer peripheral surface of this cylindrical drum and is provided with a medicinal liquid flow port on its peripheral wall. CONSTITUTION: A balloon body (a) for medicinal liquid injection is a part where the medicinal liquid is housed. This body is also a driving part to move the medicinal liquid to the point to inject the medicinal liquid to the human body. Sheet-like balloons 1 stuck to both sides of the barrel of the cylindrical drum 2 are connected to a medicinal liquid outflow assembly (b) by a lock adapter 7 installed at the rotary disk 4 and are aligned to the mouth part 9 of the cylindrical drum 7 by rotating the rotary disk 4, by which the medicinal liquid is injected to the human body from the injection needle fitted to a connector 19 via a medicinal liquid flow tube 11 and a flow rate control part 10. The sheet-like balloons 1 are stuck to both sides of the barrel of the cylindrical drum 2 and the cylindrical rotary drum 4 is fitted into the outer peripheral surface of the cylindrical drum 2.

Description

【発明の詳細な説明】Detailed Description of the Invention

【0001】[0001]

【産業上の利用分野】本発明は所定量の薬液を血管、膀
胱等に、少しずつ持続して注入するための薬液注入器具
に関し、更に詳しくはバル−ン内に加圧状態で貯蔵した
薬液を、一定速度で少しずつ持続して患者に注入するこ
とができる薬液注入器具に関する。
BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a drug solution injector for continuously injecting a predetermined amount of drug solution into a blood vessel, a bladder or the like little by little, and more specifically, a drug solution stored in a balloon under pressure. The present invention relates to a drug solution injecting device that can infuse a patient at a constant rate little by little.

【0002】[0002]

【従来の技術】従来より、抗生物質や抗ガン剤等の薬液
を血管、膀胱等に少しずつ注入する方法として、特開昭
50−108790号公報に弾性材料からなるバル−ンに薬液を
収納し、バル−ンの収縮力を利用して薬液を長時間にわ
たって人体に持続注入する器具が紹介されている。また
バル−ン材料としては特公昭59-48881号公報に合成ポリ
イソプレンを使用した薬液注入器具が紹介されている。
本発明者の一人も既に特開平4−2360号で天然ゴム製管
状体の中空内面がシリコ−ン樹脂膜で覆われた多層構造
をしたバル−ンを用いて、薬液を充填したバル−ンから
薬液をほぼ一定速度で供給する器具を特許出願してい
る。
2. Description of the Related Art Conventionally, as a method for gradually injecting a drug solution such as an antibiotic or an anticancer agent into a blood vessel, a bladder, etc.
Japanese Patent Application Laid-Open No. 50-108790 discloses a device in which a drug solution is contained in a balloon made of an elastic material and the contraction force of the balloon is used to continuously inject the drug solution into the human body for a long time. Further, as a balloon material, Japanese Patent Publication No. 59-48881 discloses a chemical injection device using synthetic polyisoprene.
One of the inventors of the present invention has already disclosed, in JP-A-4-2360, a balloon having a multilayer structure in which the hollow inner surface of a natural rubber tubular body is covered with a silicone resin film and filled with a chemical solution. Has filed a patent application for a device for supplying a drug solution at a substantially constant speed.

【0003】[0003]

【発明が解決しょうとする課題】しかしながら、かかる
バル−ン材料はいずれも一端が閉鎖された管状体あるい
は両端が開口された管状体からなるために膜厚が一定の
バル−ンを製造するのが困難で厚さ斑のある管状体しか
製造できなかった。そのために薬液を管状体に流入して
管状体を膨張させた時に、部分的に応力の集中が発生し
たりして膨張時のバル−ンの形態が変形したりするため
に、バル−ン内部の薬液を流出させたとき、バル−ン流
出口での薬液の流出速度が変動し、流量制御部入口での
薬液流入圧の変動によって常時一定速度で薬液を人体に
注入するという本発明の目的が達成されないことがしば
しば起こった。
However, since all such balloon materials are formed of a tubular body having one end closed or both ends opened, a balloon having a constant film thickness is manufactured. However, it was difficult to produce a tubular body with uneven thickness. Therefore, when the drug solution is flowed into the tubular body to expand the tubular body, the concentration of stress partially occurs and the shape of the balloon during expansion is deformed. The purpose of the present invention is to constantly inject the liquid medicine into the human body at a constant speed due to the fluctuation of the liquid medicine outflow rate at the balloon outlet when the liquid medicine is flowed out and the fluctuation of the liquid medicine inflow pressure at the inlet of the flow rate control unit. It often happened that was not achieved.

【0004】[0004]

【課題を解決するための手段】本発明者等はこれらの欠
点を解決するために鋭意研究した結果、これらの原因が
バル−ン膨張時の厚さ斑であることを見出し本発明に到
達した。すなわち、本発明は周壁に薬液を流入および流
出するための口部が設けられ、胴の両面に薬液流入によ
り膨張しうるシ−トが貼られた円筒形ドラムと、該円筒
形ドラムの外周面を摺動回転し、その周壁に薬液流通口
が設けられた円筒形の回転デイスクと、該薬液流通口か
ら延びた薬液流出アセンブリとからなる薬液注入器具で
ある。
Means for Solving the Problems As a result of intensive studies conducted by the present inventors in order to solve these drawbacks, they have found that the cause of these problems is unevenness in thickness at the time of balloon expansion and arrived at the present invention. . That is, according to the present invention, the peripheral wall is provided with mouths for inflowing and outflowing the chemical liquid, and the cylindrical drum having the sheet that is inflatable by the chemical liquid inflow on both sides of the body, and the outer peripheral surface of the cylindrical drum. Is a cylindrical liquid disk having a chemical liquid flow port provided on its peripheral wall, and a chemical liquid flow-out assembly extending from the chemical liquid flow port.

【0005】また、本発明は前記薬液注入器具におい
て、薬液流出アセンブリに薬液量を制御するための流量
制御部が設けられてなる薬液注入器具である。
Further, the present invention is the above-mentioned liquid injector, wherein the liquid outflow assembly is provided with a flow rate controller for controlling the amount of liquid.

【0006】更に本発明は前記薬液注入器具において、
円筒形ドラムの内部に設けられた中空の中心軸と、該中
心軸から円筒形ドラムの周壁に延びて周壁に口部を形成
する薬液流入通路および少なくとも1の薬液流出通路
と、中心軸の周壁に設けられた少なくとも1の薬液流出
入口とからなる薬液注入器具である。
Further, the present invention provides the above-mentioned liquid medicine injecting device,
A hollow central shaft provided inside the cylindrical drum, a chemical liquid inflow passage and at least one chemical liquid outflow passage extending from the central shaft to a peripheral wall of the cylindrical drum to form an opening in the peripheral wall, and a peripheral wall of the central shaft. And a at least one drug solution inflow / outflow port provided in the.

【0007】更にまた、本発明は前記薬液注入器具にお
いて、薬液流出通路に流量制御部が設けられてなる薬液
注入器具である。
Furthermore, the present invention is the above-mentioned chemical liquid injector, wherein the chemical liquid outflow passage is provided with a flow rate control unit.

【0008】[0008]

【作用】本発明は薬液をバル−ン内に充填して膨張した
バル−ンの収縮力を利用して、バル−ン内の薬液を患者
に注入するものであり、バル−ンから流出した薬液は薬
液流通チュ−ブ下端部の接続具に連結された穿刺針から
患者に注入される。バル−ン内への薬液の流入は、注射
器のシリンジ内に充填された薬液をシリンジ先端を回転
デイスクに設置された薬液流通口のロックアダプタ−に
接合し、回転デイスクを回転させて円筒形ドラム周壁に
設けられた口部と合致させることによって行われる。平
面構造したシ−ト状バル−ンは、その厚さ斑が管状体の
厚さ斑より小さいので、薬液を流入させてシ−トを膨張
させた際のバル−ンの厚さ斑も小さい。その結果、バル
−ンからの薬液流出時圧力変動が少なく、薬液が充満さ
れたバル−ンは、バル−ン流出口での薬液の流出速度の
変動がないので、流量制御部入口での薬液流入圧の変動
もなく、常時一定速度で薬液を人体に注入することがで
きる。
The present invention is to inject the drug solution in the balloon into the patient by utilizing the contracting force of the balloon which is filled with the drug solution and expanded. The drug solution is injected into the patient from a puncture needle connected to a connector at the lower end of the drug solution flow tube. The inflow of the drug solution into the balloon is performed by joining the drug solution filled in the syringe of the syringe to the lock adapter of the drug solution flow port installed on the rotating disk, and rotating the rotating disk to rotate the cylindrical drum. This is done by matching with the mouth provided on the peripheral wall. The thickness unevenness of the sheet-shaped balun having a planar structure is smaller than that of the tubular body, so that the thickness unevenness of the balloon when the sheet is expanded by injecting a drug solution is also small. . As a result, there is little pressure fluctuation when the chemical solution flows out from the balun, and the balun filled with the chemical solution has no fluctuation in the outflow rate of the chemical solution at the balun outlet, so the chemical solution at the inlet of the flow control unit is not changed. The liquid medicine can be constantly injected into the human body at a constant rate without fluctuation of the inflow pressure.

【0009】[0009]

【実施例】以下実施例で本発明の一例を説明する。図1
は本発明の薬液注入器具の一実施例の説明図であって、
薬液を充満させたバル−ンを薬液流出アセンブリに接続
する前の状態を示す説明図であり、図2は本発明の薬液
注入器具のバル−ン体の製造手順を示す説明図であり、
図3は図1の薬液注入器具の薬液を充満させたバル−ン
体の断面図であり、図4はシリンジ内薬液をバル−ンに
注入する際の説明図であってシリンジと薬液注入用バル
−ン体が接続していない状態を示す説明図であり、図5
は図4に示すシリンジから薬液をバル−ン内へ充填して
いるときの説明図であり、図6は本発明の薬液注入器具
の薬液を充満させたバル−ン体の他の実施例の断面図で
あり、図7は本発明薬液注入器具のバル−ン内の薬液充
填量に対するバル−ン内圧の関係を示す図であり、図8
は従来の薬液注入器具におけるバル−ン内の薬液充填量
に対するバル−ン内圧の関係を示す図である。
EXAMPLES An example of the present invention will be described below with reference to examples. FIG.
Is an explanatory view of an embodiment of the liquid medicine injection device of the present invention,
It is explanatory drawing which shows the state before connecting the balloon filled with the chemical | medical solution to the chemical | medical solution outflow assembly, and FIG. 2 is explanatory drawing which shows the manufacturing procedure of the balloon body of the chemical | medical solution injection device of this invention,
FIG. 3 is a sectional view of the balloon body filled with the drug solution of the drug solution injector of FIG. 1, and FIG. 4 is an explanatory view of injecting the drug solution in the syringe into the balloon, which is for syringe and drug solution injection. It is explanatory drawing which shows the state in which the balloon body is not connected, and FIG.
FIG. 6 is an explanatory view when the drug solution is filled in the balloon from the syringe shown in FIG. 4, and FIG. 6 shows another embodiment of the balloon body filled with the drug solution of the drug solution injector of the present invention. FIG. 7 is a cross-sectional view, and FIG. 7 is a diagram showing the relationship between the internal pressure of the balloon and the filling amount of the chemical in the balloon of the liquid injector according to the present invention.
FIG. 5 is a diagram showing the relationship between the internal pressure of the balloon and the filling amount of the chemical in the balloon in the conventional chemical injection device.

【0010】図中1はシ−ト状バル−ン、2は円筒形ド
ラム、3はハウジング、4は回転デイスク、5は固定デ
イスク、6は固定具、7はロックアダプタ−、8は凹
溝、9は口部、10は流量制御部、11は薬液流通チュ−
ブ、12はコネクタ−部、13は薬液流通口、14は薬液流出
入口、15は中心軸を示す。図1は本発明の薬液注入器具
の一実施例の説明図であって、薬液注入用バル−ン体a
と薬液流出アセンブリbとから構成されている。薬液注
入用バル−ン体aは薬液が収容される部分であるととも
に、該薬液を人体の注入箇所へ移動せしめる駆動部分で
あり、図1では円筒形ドラム2の胴の両面に貼られたシ
−ト状バル−ン1が薬液の充填によって膨張してしてい
る。バル−ン1の薬液は回転デイスクに設置されたロッ
クアダプタ−7で薬液流出アセンブリbと連結し、回転
デイスクを回転させて円筒形ドラムの口部と合致させる
ことによって、薬液は薬液流通チュ−ブ11および流量制
御部10を経て接続具19に嵌着した注射針(図示せず)か
ら人体に注入される。円筒形ドラム2の周壁には気体は
通過させるが液体は通過させない疎水性フイルタ−(図
示せず)が設けられている。
In the drawing, 1 is a sheet-shaped balun, 2 is a cylindrical drum, 3 is a housing, 4 is a rotary disk, 5 is a fixed disk, 6 is a fixture, 7 is a lock adapter, and 8 is a concave groove. , 9 is a mouth part, 10 is a flow rate control part, 11 is a chemical liquid flow tube.
Reference numeral 12 is a connector portion, 13 is a chemical liquid flow port, 14 is a chemical liquid outflow port, and 15 is a central axis. FIG. 1 is an explanatory view of an embodiment of a drug solution injector of the present invention, which is a balloon body a for drug solution injection.
And a chemical liquid outflow assembly b. The chemical liquid injection balloon a is a portion for accommodating the chemical liquid and a drive portion for moving the chemical liquid to the injection portion of the human body, and in FIG. 1, it is attached to both sides of the body of the cylindrical drum 2. -The ball-shaped balloon 1 has expanded due to the filling of the chemical liquid. The chemical solution of the balloon 1 is connected to the chemical solution outflow assembly b by a lock adapter 7 installed on the rotary disk, and the rotary disk is rotated to match with the mouth of the cylindrical drum, so that the chemical solution flows through the chemical solution distribution tube. It is injected into the human body from an injection needle (not shown) fitted to the connector 19 via the valve 11 and the flow rate control unit 10. On the peripheral wall of the cylindrical drum 2, a hydrophobic filter (not shown) which allows gas to pass but does not allow liquid to pass is provided.

【0011】シ−ト状バル−ン1は円筒形ドラム2の胴
の両面に太鼓のように貼られている。図2はバル−ン体
aの製造手順を示す説明図であって、円筒形ドラム2の
外周面に円筒形の回転デイスク4が嵌め込まれ、回転摺
動しうるようになっている。
The sheet-shaped baluns 1 are attached like drums on both sides of the body of the cylindrical drum 2. FIG. 2 is an explanatory view showing the manufacturing procedure of the balloon body a, in which a cylindrical rotary disk 4 is fitted on the outer peripheral surface of the cylindrical drum 2 so that it can rotate and slide.

【0012】回転デイスク4の周壁には薬液流通口13が
設けられており、回転デイスク4を回転摺動させた場合
円筒形ドラム2の薬液流出および薬液流入のための口部
9と合致させることによって、薬液の流入および流出が
行われる。円筒形ドラム2の外周面で円筒形の回転デイ
スク4の両隣接位置に夫々円筒形の固定デイスク5およ
び5, が回転ドラム2の外周に嵌め込まれて固定され
る。円筒形ドラム2の胴の両面であって、固定デイスク
5および5, の胴の両面にシ−ト状のバル−ン1および
, が夫々リング状の凹溝8を覆うように貼られた後
に、O−リング状の固定具6および6, を凹溝8に嵌着
して固定し、シ−ト状バル−ン1および1, が固定デイ
スク5および円筒形ドラム2に装着される。
A chemical liquid flow port 13 is provided on the peripheral wall of the rotary disk 4 so that when the rotary disk 4 is rotated and slid, it is aligned with the mouth 9 for the chemical liquid outflow and the chemical liquid inflow of the cylindrical drum 2. The inflow and outflow of the drug solution is carried out. Both adjacent positions to each cylindrical fixed disk 5 and 5 of the rotary disc 4 cylindrical outer peripheral surface of the cylindrical drum 2, is fixed by being fitted to the outer periphery of the rotary drum 2. A double-sided of the body of the cylindrical drum 2, on both sides of the fixed disk 5 and 5, the cylinder sheet - the flaps on the down 1 and 1, but to cover the respective ring-shaped concave groove 8 - DOO shaped Bal after, O- ring-shaped fixing tool 6 and 6, the fixed and fitted into the concave groove 8, shea - DOO shaped Val - down 1 and 1, is attached to the fixed disk 5 and the cylindrical drum 2.

【0013】図3は円筒形デイスク2の胴の両端に固定
具6で嵌着されたシ−ト状バル−ン1の薬液を充満させ
た際のバル−ン体aの断面図が図示されている。バル−
ン1は、薬液が流入されていると球状をしており、患者
への薬液注入量、注入時間などに応じて種々の大きさ、
肉厚のものを用いることができ、本発明においては特に
限定されるものでない。本発明で使用するバル−ン1材
料としては、薬液を流入することによって膨張し、かつ
膨張したバル−ンが薬液を流出する収縮圧を有するもの
が好ましく、シリコ−ンゴム、ブチルゴム、アクリロニ
トリルブタジェンゴム、ブタジェンゴム、イソプレンゴ
ム、ウレタンゴム、スチレンブタジェンゴム、ペルプレ
ン、クレイトンゴムなどの弾性重合体または天然ゴム、
これらの重合体混合物、またはこれらの物質の添加剤を
除去したのち人体に無害の酸化防止剤を添加した加工物
質、またはラミネ−ト等が挙げられる。ラミネ−トとし
て使用される際には、これらの材料は外層として使用さ
れ、内層には外層材料より収縮応力の小さい弾性ゴムや
熱可塑性樹脂が使用される。熱可塑性樹脂としては、ポ
リエチレン、ポリプロピレン、ポリ塩化ビニル、ポリエ
ステル、ポリアミド等の未延伸、1軸延伸または2軸延
伸フイルムが挙げられる。
FIG. 3 is a sectional view of the balloon body a when the chemical solution of the sheet-shaped balloon 1 fitted with the fixtures 6 is filled at both ends of the barrel of the cylindrical disk 2. ing. Bar
1 has a spherical shape when the liquid medicine is flowing in, and has various sizes depending on the amount of liquid medicine to be injected into the patient, the injection time, and the like.
Thick materials can be used, and there is no particular limitation in the present invention. As the balun 1 material used in the present invention, it is preferable that the balun 1 material is expanded by inflow of a chemical liquid, and the expanded balun has a contraction pressure at which the chemical liquid flows out. Silicone rubber, butyl rubber, acrylonitrile butadiene Elastic polymers or natural rubbers such as rubber, butadiene rubber, isoprene rubber, urethane rubber, styrene butadiene rubber, perprene and Kraton rubber,
Examples thereof include a mixture of these polymers, a processed substance obtained by removing additives of these substances and then adding an innocuous antioxidant to the human body, or laminate. When used as a laminate, these materials are used as an outer layer, and an elastic rubber or a thermoplastic resin having a shrinkage stress smaller than that of the outer layer material is used for the inner layer. Examples of the thermoplastic resin include unstretched, uniaxially stretched or biaxially stretched films of polyethylene, polypropylene, polyvinyl chloride, polyester, polyamide and the like.

【0014】図3において円筒形ドラム2の一端に薬液
流入および薬液流出のための口部(図示せず)が設けら
れており、円筒形の回転デイスク4の薬液流通口13と合
致して薬液流入および薬液流出をする。回転デイスク4
の薬液流通口13は短円筒状形状をしており回転デイスク
4と一体に形成されている。円筒形ドラム2のシ−ト状
バル−ン1側には半球状のハウジング3が両面側に夫々
設けられている。例えば半球状ハウジングの開口部内側
に形成されたネジと固定デイスク5の外壁に形成された
ネジを螺合することによってハウジング3が形成され
る。ハウジング3はバル−ン1が外部の鋭利な物体に触
れて破損するのを防止するとともに、バル−ン自体のピ
ンホ−ルなどの欠陥によってバル−ン1から液洩れが発
生した場合に外部に薬液が飛散しないように薬液を密封
する機能を果たす箇所である。ハウジング3の適宜の箇
所には空気抜きの開口部(図示せず)が形成されてお
り、該開口部に空気は通過させるが薬液は通過させない
疎水性フイルタ−が設けられているのが好ましい。
In FIG. 3, a mouth (not shown) for inflowing and outflowing the liquid medicine is provided at one end of the cylindrical drum 2, and the liquid medicine matches the liquid flow port 13 of the cylindrical rotary disk 4 and the liquid medicine. Inflow and outflow of chemicals. Rotating disk 4
The chemical liquid flow port 13 has a short cylindrical shape and is formed integrally with the rotary disk 4. A hemispherical housing 3 is provided on both sides of the sheet drum 1 side of the cylindrical drum 2. For example, the housing 3 is formed by screwing a screw formed inside the opening of the hemispherical housing and a screw formed on the outer wall of the fixed disk 5. The housing 3 prevents the ball 1 from being damaged by touching an external sharp object, and is also exposed to the outside when liquid is leaked from the ball 1 due to a defect such as a pin hole of the ball itself. It is a part that functions to seal the chemical liquid so that the chemical liquid does not splash. An opening (not shown) for venting air is formed at an appropriate portion of the housing 3, and a hydrophobic filter that allows air to pass but does not allow a chemical solution to pass is preferably provided in the opening.

【0015】薬液流通口13は、回転デイスク4の周壁に
設けられており、図3にみられるようにロックアダプタ
−7の内周面がルア−テ−パ−状に形成されたほぼ円筒
状の接続具である。図4および図5はシリンジ内の薬液
を薬液流通口13からバル−ン内へ流入させる場合のロッ
クアダプタ−7とシリンジ16の針基17とを接合させた時
の断面図である。ロックアダプタ−7内に注射器のシリ
ンジ16を挿入し、このシリンジ16の針基17をロックアダ
プタ−7のルア−テ−パ−状の雌部23の内周面に押しつ
け、ロックアダプタ−7のネジ部18とシリンジ16のネジ
部21とで螺合して装着させる。バル−ン1内部の薬液を
流出させる場合には、ロックアダプタ−7の端部外周に
薬液流出アセンブリbを接続する。ロックアダプタ−7
の端部外周にあるネジ部18と薬液流出アセンブリbのコ
ネクタ−部12のネジ部20とが螺合して薬液注入用バル−
ン体aと薬液流出アセンブリbとの接続が行われる。こ
の接続は螺合以外に嵌合で行うようにしてもよい。薬液
の流出および流入を一箇所の薬液流通口13で説明した
が、本発明はその実施例に限定されるものでなく、薬液
の流出および流入を別々の箇所から行ってもよい。例え
ば薬液流通路13から薬液流出だけを行い、薬液流入は薬
液流通口13の対向する円筒形ドラム2の位置に設けても
よい。
The chemical liquid flow port 13 is provided on the peripheral wall of the rotary disk 4, and as shown in FIG. 3, the inner peripheral surface of the lock adapter 7 is formed in a luer taper shape and is substantially cylindrical. It is a connection tool. 4 and 5 are cross-sectional views when the lock adapter 7 and the needle base 17 of the syringe 16 are joined when the drug solution in the syringe is caused to flow into the balloon from the drug solution flow port 13. The syringe 16 of the syringe is inserted into the lock adapter-7, and the needle base 17 of the syringe 16 is pressed against the inner peripheral surface of the luer taper-shaped female portion 23 of the lock adapter-7, The threaded portion 18 and the threaded portion 21 of the syringe 16 are screwed together and attached. When the chemical solution inside the balloon 1 is to be discharged, the chemical solution outflow assembly b is connected to the outer periphery of the end portion of the lock adapter 7. Lock adapter-7
The screw portion 18 on the outer circumference of the end of the connector and the screw portion 20 of the connector portion 12 of the chemical liquid outflow assembly b are screwed together to form a chemical liquid injection valve.
The connection between the body a and the chemical liquid outflow assembly b is performed. This connection may be made by fitting instead of screwing. Although the outflow and the inflow of the chemical liquid have been described by using the chemical liquid flow port 13 at one place, the present invention is not limited to the embodiment, and the outflow and the inflow of the chemical liquid may be performed at different places. For example, only the chemical liquid may be discharged from the chemical liquid flow passage 13, and the chemical liquid may be provided at the position of the cylindrical drum 2 facing the chemical liquid flow port 13.

【0016】薬液流出アセンブリbはロックアダプタ−
7に接続されるコネクタ−部12と、薬液流通チュ−ブ11
と、接続具19とで構成されており、必要により流量制御
部10が設けられてもよい。流量制御部10は薬液の流量を
制御する部分であり、本出願人が既に出願した特開平1-
135356号や特開平2-11160号で提案した下流側先端の
閉塞されたパイプであって少なくとも1個の微細孔を有
するパイプ、多孔質ガラスパイプなどの有孔パイプ、
内径が小径のステンレスパイプなどを用いることがで
きる。流量制御部10は薬液流通チュ−ブ11の先端より前
のコネクタ−部12の中、あるいは薬液流通チュ−ブ11の
先端より後で接続具21とコネクタ−部12との間に設けら
れる。薬液流通チュ−ブ11は軟質ポリ塩化ビニル、ポリ
プロピレン、ポリエステルなどからなり、その他端には
ルア−テ−パ−状の接続具19が設けられ、接続具を介し
て静脈針やPSVセットなどが接続される。接続具19に
は静脈圧などにより薬液が逆流するのを防止するための
逆止弁(図示せず)を装備してもよい。
The chemical liquid outflow assembly b is a lock adapter-
7, a connector part 12 to be connected to 7, and a chemical liquid distribution tube 11
And the connection tool 19, and the flow rate control unit 10 may be provided if necessary. The flow rate control section 10 is a section for controlling the flow rate of the chemical liquid, and the applicant has already filed JP-A-1-
135356 and Japanese Patent Laid-Open No. 2-11160, which is a pipe having a closed downstream end and having at least one fine hole, a perforated pipe such as a porous glass pipe,
A stainless pipe having a small inner diameter can be used. The flow rate control unit 10 is provided in the connector portion 12 before the tip of the chemical liquid flow tube 11 or between the connector 21 and the connector portion 12 after the tip of the chemical liquid flow tube 11. The chemical liquid distribution tube 11 is made of soft polyvinyl chloride, polypropylene, polyester, etc., and has a luer taper-like connecting tool 19 at the other end, through which a venous needle, PSV set, etc. can be connected. Connected. The connector 19 may be equipped with a check valve (not shown) for preventing the backflow of the drug solution due to venous pressure or the like.

【0017】図8は本発明薬液注入器具の他の実施例を
示すバル−ン体の断面図である。中心軸15が円筒形ドラ
ム2の中心点を通って円筒形ドラム2の薬液を流入およ
び流出するための口部9である一端から対向する他端ま
で延びており、中心軸15の中心点から少なくとも1の薬
液流通路22が円筒形ドラム2の周壁まで延びており、夫
々その周壁に口部を形成している。薬液流出通路22に
は、夫々流量速度が異なる流量制御部が設けられてお
り、回転デイスク4を回転するだけで所望の流速を得る
ことができる。この際、薬液流出アセンブリbの流量制
御部10は設けても設けなくてもよい。ロックアダプタ−
7から薬液流通口13および口部9を経て流入された薬液
は、中心軸15の薬液流出入口14からバル−ン内に流入さ
れバル−ン1を膨張させる。次いで、薬液流出通路22の
いずれかの通路の回転ドラム2の周壁の口部を回転デイ
スク4の薬液流通口13と合致させて、薬液を充満したバ
ル−ンの収縮応力を利用して薬液流通アセンブリbを経
て人体に薬液が注入される。図8では薬液のバル−ン内
への流入は中心軸15の内腔を経て薬液流出入口14からバ
ル−ン内部へ流入するようになっているが、円筒形ドラ
ム2の他の周壁から薬液が流入されてもよい。
FIG. 8 is a sectional view of a balloon body showing another embodiment of the drug solution injector of the present invention. The central axis 15 extends from one end, which is the mouth 9 for inflowing and outflowing the chemical liquid of the cylindrical drum 2 through the central point of the cylindrical drum 2, to the other end opposite thereto, and from the central point of the central axis 15. At least one chemical liquid flow passage 22 extends to the peripheral wall of the cylindrical drum 2, and a mouth portion is formed on each peripheral wall. The chemical liquid outflow passages 22 are provided with flow rate control units having different flow rate rates, and a desired flow rate can be obtained only by rotating the rotary disk 4. At this time, the flow rate control unit 10 of the chemical liquid outflow assembly b may or may not be provided. Lock adapter-
The chemical liquid introduced from 7 through the chemical liquid flow port 13 and the mouth portion 9 flows into the balloon from the chemical liquid outlet 14 of the central shaft 15 to expand the balloon 1. Next, the mouth of the peripheral wall of the rotary drum 2 in any one of the chemical liquid outflow passages 22 is matched with the chemical liquid flow port 13 of the rotary disk 4, and the chemical liquid is distributed by utilizing the contraction stress of the balloon filled with the chemical liquid. The drug solution is injected into the human body through the assembly b. In FIG. 8, the chemical solution flows into the balloon through the inner cavity of the central shaft 15 through the chemical solution inlet / outlet port 14 into the interior of the balloon. May be flowed in.

【0018】次に、本発明の薬液注入器具の使用方法の
一例について説明する。薬液のバル−ンへの注入は、図
4および図5に示すようにロックアダプタ−7内に注射
器のシリンジ16を挿入し、このシリンジ16の針基17をロ
ックアダプタ−7のルア−テ−パ−状の雌部23の内周面
に押しつけ、ロックアダプタ−7のネジ部18とシリンジ
16のネジ部21とで螺合して装着させる。薬液を充填する
につれて、バル−ン1は膨張する。所定量の薬液充填が
終わると注射器をロックアダプタ−7から抜き取る。次
に薬液流出アセンブリbのコネクタ−部12のネジ部22と
ロックアダプタ−7のネジ部18とを螺合してバル−ン体
aと薬液流出アセンブリbとを接続する。その後は接続
具21を介してPSVセットなどに接続し空気抜きなどの
所定の操作を行った後に患者の体内に薬液の注入が行わ
れる。
Next, an example of a method of using the drug solution injector of the present invention will be described. To inject the drug solution into the balloon, as shown in FIGS. 4 and 5, the syringe 16 of the syringe is inserted into the lock adapter 7, and the needle base 17 of the syringe 16 is attached to the luer tee of the lock adapter 7. It is pressed against the inner peripheral surface of the par-shaped female part 23, and the screw part 18 of the lock adapter 7 and the syringe
It is attached by screwing with 16 screw parts 21. The balloon 1 expands as the chemical is filled. When the prescribed amount of drug solution is filled, the syringe is pulled out from the lock adapter-7. Next, the screw portion 22 of the connector portion 12 of the chemical liquid outflow assembly b and the screw portion 18 of the lock adapter 7 are screwed together to connect the balloon body a and the chemical liquid outflow assembly b. After that, after connecting to the PSV set or the like via the connecting tool 21 and performing a predetermined operation such as air venting, the drug solution is injected into the patient's body.

【0019】[0019]

【実施例1】厚さ150 μのポリエチレンシ−トと厚さ10
0 μの天然ゴムシ−トのラミネ−トシ−トを直径600mm
の円形シ−トに切断した。天然ゴムシ−トは、加硫され
た天然ゴムシ−ト(小峰ゴム社製)をアセトン・ヘキサ
ン混合溶剤(混合容積比1:2)でソックスレ−抽出を
3時間行い、天然ゴムシ−ト中の添加剤を抽出除去し
た。次いで該シ−トを1,3,5−トリメチル−2,
4,6−トリス(3,5−ジ−t−ブチル−4−ヒドロ
キシベンジル)ベンゼン(以下BHTという)のアセト
ン・ヘキサン混合溶剤(混合容積比1:2)の溶液(濃
度0.01g/ml)中に25℃の温度で24時間浸漬し、該シ−ト
中に酸化防止剤であるBHTを含浸させた。
Example 1 A polyethylene sheet having a thickness of 150 μm and a thickness of 10
600 μm diameter of 0 μm natural rubber sheet laminate sheet
It was cut into a circular sheet. As the natural rubber sheet, vulcanized natural rubber sheet (manufactured by Komine Rubber Co., Ltd.) was subjected to Soxhlet extraction for 3 hours with a mixed solvent of acetone and hexane (mixing volume ratio 1: 2), and added to the natural rubber sheet. The agent was extracted and removed. Then the sheet is treated with 1,3,5-trimethyl-2,
A solution of 4,6-tris (3,5-di-t-butyl-4-hydroxybenzyl) benzene (hereinafter referred to as BHT) in a mixed solvent of acetone and hexane (mixing volume ratio 1: 2) (concentration 0.01 g / ml) The sheet was immersed at a temperature of 25 ° C. for 24 hours to impregnate the sheet with BHT as an antioxidant.

【0020】その後天然ゴムシ−トをエタノ−ルで洗浄
し25℃の温度で12時間乾燥させて製造した。この天然ゴ
ムシ−トをポリエチレンシ−トと接着剤を用いてラミネ
−トした。このラミネ−トシ−トのポリエチレンシ−ト
側を内側にして図2の方法で円筒形ドラムの胴の両面に
貼りつけ、図3のようなバル−ン体を成形した。このバ
ル−ン体に100ml の水を流入させてバル−ンを膨張さ
せ、薬液流出アセンブリbを取りつけて流出速度100ml/
時間で流出させた時のバル−ン内液量に対するバル−ン
内圧の関係を図7に示す。図7にみられるように水量の
増減に対してバル−ン内の水量が40ml以上ではバル−ン
内圧はほぼ一定の圧力で変動し、ほぼ一定の圧力で薬液
がバル−ンから流出されることが示されている。
After that, the natural rubber sheet was washed with ethanol and dried at a temperature of 25 ° C. for 12 hours to prepare a sheet. The natural rubber sheet was laminated with a polyethylene sheet and an adhesive. With the polyethylene sheet side of this laminate sheet inside, it was attached to both sides of the barrel of the cylindrical drum by the method of FIG. 2 to form a balloon body as shown in FIG. 100 ml of water is made to flow into this balun to expand the balun, and the chemical liquid outflow assembly b is attached to make the outflow rate 100 ml /
FIG. 7 shows the relationship between the amount of liquid in the balloon and the internal pressure of the balloon when flowing out over time. As shown in Fig. 7, when the amount of water in the balun is 40 ml or more with respect to the increase or decrease in the amount of water, the balun internal pressure fluctuates at a substantially constant pressure, and the chemical solution is discharged from the balun at a substantially constant pressure. Is shown.

【0021】[0021]

【比較例1】一端が閉鎖したポリエチレン製管状体(内
径 4.3mm、外径 4.6mm、長さ60mm)を縦軸方向に折り畳
んだ後、閉鎖端付近の外面をシリコ−ンオイルに浸漬さ
せてシリコ−ンオイルの膜を形成させた。一方、一端が
閉鎖した加硫された天然ゴム製管状体(小峰ゴム社製)
を実施例1と同様に処理して処理済天然ゴム製管状体
(内径 5.0mm、外径 7.0mm、長さ95mm)を製造した。閉
鎖端付近の外面がシリコ−ンオイルで塗布されたポリエ
チレン製管状体を処理済天然ゴム製管状体の内部に挿入
してその隙間に更にシリコ−ンオイルを注入し両管状体
の開口部を固定させた後、ポリエチレン製管状体内部に
圧縮空気を注入することによって両管状体を膨張させ
た。処理済天然ゴム製管状体の長さをポリエチレン製管
状体に合うように切断した後天然ゴム製管状体の切断部
を閉鎖した。次いで、両管状体内部の空気を放出してバ
ル−ンを製造した。両管状体の隙間に存在するシリコ−
ンオイル層は全面にいきわたっており、その平均厚さは
0.09μm であった。このようにして製造したバル−ンを
用いて特開平4-96761号公報に記載のような薬液注入用
バル−ン体aを成形し、100ml の水を注射器のシリンジ
からバル−ン内部に注入した。ポリエチレン製管状体と
天然ゴム製管状体の間には空隙箇所はなく、天然ゴム製
管状体の内面がポリエチレン製管状体の外面に密着して
バル−ンは膨張した。次いで、図1に示す薬液流出アセ
ンブリbのコネクタ−部とロックアダプタ−とを接続す
ることによってバル−ン内の水は薬液流通チュ−ブ側へ
流出した。
[Comparative Example 1] A polyethylene tubular body (inner diameter 4.3 mm, outer diameter 4.6 mm, length 60 mm) with one end closed was folded in the vertical axis direction, and the outer surface near the closed end was dipped in silicone oil. -A film of oil was formed. On the other hand, vulcanized natural rubber tubular body (made by Komine Rubber Co., Ltd.) with one end closed
Was treated in the same manner as in Example 1 to produce a treated natural rubber tubular body (inner diameter 5.0 mm, outer diameter 7.0 mm, length 95 mm). Insert the polyethylene tubular body whose outer surface near the closed end was coated with silicone oil into the treated natural rubber tubular body, and further inject silicone oil into the gap to fix the openings of both tubular bodies. After that, both tubular bodies were expanded by injecting compressed air into the polyethylene tubular body. After the length of the treated natural rubber tubular body was cut so as to fit the polyethylene tubular body, the cut portion of the natural rubber tubular body was closed. Then, the air inside the both tubular bodies was discharged to manufacture a balloon. Silicon present in the gap between both tubular bodies
The oil layer covers the entire surface and its average thickness is
It was 0.09 μm. Using the balloon thus manufactured, a balloon body a for injecting a chemical solution as described in JP-A-4-967671 is molded, and 100 ml of water is injected into the balloon from a syringe of a syringe. did. There was no space between the polyethylene tubular body and the natural rubber tubular body, and the inner surface of the natural rubber tubular body was in close contact with the outer surface of the polyethylene tubular body and the balloon expanded. Then, by connecting the connector portion and the lock adapter of the chemical liquid outflow assembly b shown in FIG. 1, the water in the balloon was flown out to the chemical liquid flow tube side.

【0022】実施例1ど同様に100ml/時間の流出速度で
水を流出させた時のバル−ン内液量に対するバル−ン内
圧の関係を図8に示す。図8にみられるように、薬液流
出時と流入時のバル−ン内圧に差があり一定の圧力でバ
ル−ン内の薬液が流出しなかったことを示す。
FIG. 8 shows the relationship between the amount of liquid in the balloon and the internal pressure of the balloon when water was allowed to flow out at an outflow rate of 100 ml / hour as in Example 1. As shown in FIG. 8, there is a difference in the internal pressure of the balun between the time when the chemical solution flows out and the time when the chemical solution flows out.

【0023】[0023]

【発明の効果】平面構造したシ−ト状バル−ンは、その
厚さ斑が管状体の厚さ斑より小さいので、薬液を流入さ
せてシ−トを膨張させた際のバル−ンの厚さ斑も小さ
い。その結果、バル−ンからの薬液流出時圧力変動が少
なく、薬液が充満されたバル−ンは、バル−ン流出口で
の薬液の流出速度の変動がないので、流量制御部入口で
の薬液流入圧の変動も少なく、常時一定速度で薬液を人
体に注入することができる。また、薬液の流入および流
出は、回転デイスクの薬液流通口を円筒形ドラムの口部
と合致させるだけで行うことができるので、操作が簡単
で口部での薬液の液洩れがない
EFFECTS OF THE INVENTION Since the sheet-shaped balun having a planar structure has a thickness unevenness smaller than that of the tubular body, the balun when the sheet is expanded by injecting a chemical solution Thickness unevenness is also small. As a result, there is little pressure fluctuation when the chemical solution flows out from the balun, and the balun filled with the chemical solution has no fluctuation in the outflow rate of the chemical solution at the balun outlet, so the chemical solution at the inlet of the flow control unit is not changed. The fluctuation of the inflow pressure is small, and the liquid medicine can be constantly injected into the human body at a constant rate. In addition, the inflow and outflow of the drug solution can be performed only by matching the drug solution flow port of the rotary disk with the port part of the cylindrical drum, so that the operation is easy and the drug solution does not leak at the port part.

【図面の簡単な説明】[Brief description of drawings]

【図1】本発明の薬液注入器具の一実施例の説明図であ
って、薬液注入用バル−ン体を薬液流出アセンブリに接
続する前の状態を示す説明図。
FIG. 1 is an explanatory view of an embodiment of a liquid medicine injecting device of the present invention, showing a state before connecting a liquid medicine injecting balun body to a liquid medicine outflow assembly.

【図2】本発明の薬液注入器具のバル−ン体の製造手順
を示す説明図。
FIG. 2 is an explanatory view showing a procedure for manufacturing a balloon body of the liquid medicine injection device of the present invention.

【図3】図1の薬液注入器具の薬液を充満させたバル−
ン体の断面図。
FIG. 3 is a valve filled with the liquid medicine of the liquid medicine injector of FIG.
FIG.

【図4】シリンジ内薬液をバル−ンに注入する際の説明
図であってシリンジと薬液注入用バル−ン体が接続して
いない状態を示す説明図。
FIG. 4 is an explanatory diagram when injecting the drug solution in the syringe into the balloon, and is an explanatory view showing a state in which the syringe and the balloon body for injecting the drug solution are not connected.

【図5】図4に示すシリンジから薬液をバル−ン内へ充
填するときの説明図。
FIG. 5 is an explanatory view of filling a drug solution into the balloon from the syringe shown in FIG.

【図6】本発明の薬液注入器具の薬液を充満させたバル
−ン体の他の実施例の断面図。
FIG. 6 is a cross-sectional view of another embodiment of the balloon body filled with the drug solution of the drug solution injector of the present invention.

【図7】本発明の薬液注入器具のバル−ン内の薬液充填
量に対するバル−ン内圧の関係を示す図。
FIG. 7 is a view showing the relationship between the internal pressure of the balloon and the filling amount of the chemical in the balloon of the chemical injection device of the present invention.

【図8】従来の薬液注入器具におけるバル−ン内の薬液
充填量に対するバル−ン内圧の関係を示す図。
FIG. 8 is a view showing a relationship between the internal pressure of the balloon and the filling amount of the chemical in the balloon in the conventional liquid injector.

【符号の説明】[Explanation of symbols]

1 シ−ト状バル−ン 2 円筒形ドラム 3 ハウジング 4 回転デイスク 5 固定デイスク 6 固定具 7 ロックアダプタ− 8 凹溝 9 口部 10 流量制御部 11 薬液流通チュ−ブ 12 コネクタ−部 13 薬液流通口 14 薬液流出入口 1 Sheet Balloon 2 Cylindrical Drum 3 Housing 4 Rotating Disk 5 Fixed Disk 6 Fixing Tool 7 Lock Adapter-8 Lock Groove 9 Mouth Port 10 Flow Control Section 11 Chemical Flow Tube 12 Connector Section 13 Chemical Flow Mouth 14 Chemical liquid outlet

─────────────────────────────────────────────────────
─────────────────────────────────────────────────── ───

【手続補正書】[Procedure amendment]

【提出日】平成6年9月21日[Submission date] September 21, 1994

【手続補正1】[Procedure Amendment 1]

【補正対象書類名】明細書[Document name to be amended] Statement

【補正対象項目名】0016[Correction target item name] 0016

【補正方法】変更[Correction method] Change

【補正内容】[Correction content]

【0016】薬液流出アセンブリbはロックアダプタ−
7に接続されるコネクタ−部12と、薬液流通チュ−ブ11
と、接続具19とで構成されており、必要により流量制御
部10が設けられてもよい。流量制御部10は薬液の流量を
制御する部分であり、本出願人が既に出願した特開平1-
135356号や特開平2-11160号で提案した下流側先端の
閉塞されたパイプであって少なくとも1個の微細孔を有
するパイプ、多孔質ガラスパイプなどの有孔パイプ、
内径が小径のステンレスパイプなどを用いることがで
きる。流量制御部10は薬液流通チュ−ブ11の先端より前
のコネクタ−部12の中、あるいは薬液流通チュ−ブ11の
先端より後で接続具19とコネクタ−部12との間に設けら
れる。薬液流通チュ−ブ11は軟質ポリ塩化ビニル、ポリ
プロピレン、ポリエステルなどからなり、その他端には
ルア−テ−パ−状の接続具19が設けられ、接続具を介し
て静脈針やPSVセットなどが接続される。接続具19に
は静脈圧などにより薬液が逆流するのを防止するための
逆止弁(図示せず)を装備してもよい。
The chemical liquid outflow assembly b is a lock adapter-
7, a connector part 12 to be connected to 7, and a chemical liquid distribution tube 11
And the connection tool 19, and the flow rate control unit 10 may be provided if necessary. The flow rate control section 10 is a section for controlling the flow rate of the chemical liquid, and the applicant has already filed JP-A-1-
A pipe having a closed end on the downstream side and having at least one fine hole, a perforated pipe such as a porous glass pipe proposed in 135356 and Japanese Patent Laid-Open No. 2-11160.
A stainless pipe having a small inner diameter can be used. The flow rate control unit 10 is provided in the connector section 12 before the tip of the chemical solution flow tube 11 or between the connector 19 and the connector section 12 after the tip of the chemical solution flow tube 11. The chemical liquid distribution tube 11 is made of soft polyvinyl chloride, polypropylene, polyester, etc., and has a luer taper-like connecting device 19 provided at the other end, and a venous needle, a PSV set, etc. can be connected through the connecting device. Connected. The connector 19 may be equipped with a check valve (not shown) for preventing the backflow of the drug solution due to venous pressure or the like.

【手続補正2】[Procedure Amendment 2]

【補正対象書類名】明細書[Document name to be amended] Statement

【補正対象項目名】0019[Correction target item name] 0019

【補正方法】変更[Correction method] Change

【補正内容】[Correction content]

【0019】[0019]

【実施例1】厚さ150 μのポリエチレンシ−トと厚さ10
0 μの天然ゴムシ−トのラミネ−トシ−トを直径60mmの
円形シ−トに切断した。天然ゴムシ−トは、加硫された
天然ゴムシ−ト(小峰ゴム社製)をアセトン・ヘキサン
混合溶剤(混合容積比1:2)でソックスレ−抽出を3
時間行い、天然ゴムシ−ト中の添加剤を抽出除去した。
次いで該シ−トを1,3,5−トリメチル−2,4,6
−トリス(3,5−ジ−t−ブチル−4−ヒドロキシベ
ンジル)ベンゼン(以下BHTという)のアセトン・ヘ
キサン混合溶剤(混合容積比1:2)の溶液(濃度0.01
g/ml)中に25℃の温度で24時間浸漬し、該シ−ト中に酸
化防止剤であるBHTを含浸させた。その後天然ゴムシ
−トをエタノ−ルで洗浄し25℃の温度で12時間乾燥させ
て製造した。この天然ゴムシ−トをポリエチレンシ−ト
と接着剤を用いてラミネ−トした。このラミネ−トシ−
トのポリエチレンシ−ト側を内側にして図2の方法で円
筒形ドラムの胴の両面に貼りつけ、図3のようなバル−
ン体を成形した。このバル−ン体に100ml の水を流入さ
せてバル−ンを膨張させ、薬液流出アセンブリbを取り
つけて流出速度100ml/時間で流出させた時のバル−ン内
液量に対するバル−ン内圧の関係を図7に示す。図7に
みられるように水量の増減に対してバル−ン内の水量が
40ml以上ではバル−ン内圧はほぼ一定の圧力で変動し、
ほぼ一定の圧力で薬液がバル−ンから流出されることが
示されている。
Example 1 A polyethylene sheet having a thickness of 150 μm and a thickness of 10
A 0 .mu.m natural rubber sheet laminate sheet was cut into a circular sheet having a diameter of 60 mm. As for the natural rubber sheet, vulcanized natural rubber sheet (manufactured by Komine Rubber Co., Ltd.) was subjected to Soxhlet extraction with a mixed solvent of acetone / hexane (mixing volume ratio 1: 2) to 3 times.
This was carried out for a period of time to extract and remove the additives in the natural rubber sheet.
Then, the sheet was treated with 1,3,5-trimethyl-2,4,6.
-A solution of tris (3,5-di-t-butyl-4-hydroxybenzyl) benzene (hereinafter referred to as BHT) in a mixed solvent of acetone / hexane (mixing volume ratio 1: 2) (concentration 0.01
g / ml) at a temperature of 25 ° C. for 24 hours to impregnate the sheet with BHT as an antioxidant. Then, the natural rubber sheet was washed with ethanol and dried at a temperature of 25 ° C. for 12 hours to produce a sheet. The natural rubber sheet was laminated with a polyethylene sheet and an adhesive. This Laminate Toshi
The polyethylene sheet side of the cylinder is attached to both sides of the barrel of the cylindrical drum by the method shown in FIG.
The molded body was molded. 100 ml of water was made to flow into this balun to expand the balun, and the balun internal pressure relative to the amount of balun internal liquid when the chemical liquid outflow assembly b was attached and the outflow rate was 100 ml / hour The relationship is shown in FIG. As can be seen in Fig. 7, the amount of water in the balloon is
Above 40 ml, the balloon internal pressure fluctuates at a nearly constant pressure,
It has been shown that at nearly constant pressure, the drug solution exits the balloon.

Claims (4)

【特許請求の範囲】[Claims] 【請求項1】 周壁に薬液を流入および流出するための
口部が設けられ、胴の両面に薬液流入により膨張しうる
シ−トが貼られた円筒形ドラムと、該円筒形ドラムの外
周面を摺動回転し、その周壁に薬液流通口が設けられた
円筒形の回転デイスクと、該薬液流通口から延びた薬液
流出アセンブリとからなる薬液注入器具。
1. A cylindrical drum having a peripheral wall provided with mouths for inflowing and outflowing a chemical liquid, and having a sheet attached to both sides of a body, the sheet being expandable by the chemical liquid inflow, and an outer peripheral surface of the cylindrical drum. A liquid medicine injecting device comprising a cylindrical rotary disk, which is slidably rotated, and whose peripheral wall is provided with a liquid medicine flow port, and a liquid medicine outflow assembly extending from the liquid medicine flow port.
【請求項2】 薬液流出アセンブリに薬液量を制御する
ための流量制御部が設けられてなる請求項1記載の薬液
注入器具。
2. The drug solution injector according to claim 1, wherein the drug solution outflow assembly is provided with a flow rate controller for controlling the drug solution amount.
【請求項3】 円筒形ドラムの内部に設けられた中空の
中心軸と、該中心軸から円筒形ドラムの周壁に延びて周
壁に口部を形成する薬液流入通路および少なくとも1の
薬液流出通路と、中心軸の周壁に設けられた少なくとも
1の薬液流出入口とからなる請求項1または2記載の薬
液注入器具。
3. A hollow central shaft provided inside the cylindrical drum, a chemical liquid inflow passage extending from the central shaft to a peripheral wall of the cylindrical drum to form an opening in the peripheral wall, and at least one chemical liquid outflow passage. 3. The chemical liquid injector according to claim 1, further comprising at least one chemical liquid outflow port provided on the peripheral wall of the central axis.
【請求項4】 薬液流出通路に流量制御部が設けられて
なる請求項3記載の薬液注入器具。
4. The drug solution injector according to claim 3, wherein a flow rate control unit is provided in the drug solution outflow passage.
JP6217682A 1994-09-12 1994-09-12 Medicinal liquid injecting appliance Pending JPH0880352A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP6217682A JPH0880352A (en) 1994-09-12 1994-09-12 Medicinal liquid injecting appliance

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6217682A JPH0880352A (en) 1994-09-12 1994-09-12 Medicinal liquid injecting appliance

Publications (1)

Publication Number Publication Date
JPH0880352A true JPH0880352A (en) 1996-03-26

Family

ID=16708072

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6217682A Pending JPH0880352A (en) 1994-09-12 1994-09-12 Medicinal liquid injecting appliance

Country Status (1)

Country Link
JP (1) JPH0880352A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015506776A (en) * 2012-02-10 2015-03-05 キンバリー クラーク ワールドワイド インコーポレイテッド Improved inflatable elastomer pump for infusion assemblies
CN106031805A (en) * 2015-03-11 2016-10-19 李荣辉 An elastic infusion device and a method for manufacturing the same

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015506776A (en) * 2012-02-10 2015-03-05 キンバリー クラーク ワールドワイド インコーポレイテッド Improved inflatable elastomer pump for infusion assemblies
CN106031805A (en) * 2015-03-11 2016-10-19 李荣辉 An elastic infusion device and a method for manufacturing the same

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