JPH08508976A - 改善化免疫療法用組成物 - Google Patents
改善化免疫療法用組成物Info
- Publication number
- JPH08508976A JPH08508976A JP6516525A JP51652594A JPH08508976A JP H08508976 A JPH08508976 A JP H08508976A JP 6516525 A JP6516525 A JP 6516525A JP 51652594 A JP51652594 A JP 51652594A JP H08508976 A JPH08508976 A JP H08508976A
- Authority
- JP
- Japan
- Prior art keywords
- cell wall
- species
- parvum
- composition
- corynebacterium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (1)
- 【特許請求の範囲】 1. ヒトもしくは動物の免疫系を刺激化する方法であって、そのヒトもしく は動物に、油を含まないミコバクテリア細胞壁抽出物の水性懸濁物の有効量を投 与することを含むんでなる上記方法。 2. ミコバクテリア細胞壁抽出物が、バチレ カルメッテ−グエリン(ba cille Calmette−Guerin)(BCG)、コリネバクテリウ ム パルブム(Corynebacterium parvum)、ミコバクテ リウム(Mycobacterium)種、コリネバクテリウム(Coryne bacterium )種、コリネホルム(Coryneform)細菌、プロピ オネバクテリウム アクネス(Propionebacterium acne s )(C.パルブム(C.parvum))、ロドコッカス(Rhodococ cus )種、エウバクテリウム(Eubacterium)種、リステリア モ ノサイトゲネス(Listeria monocytogenes)、ボルデテ ラ(Bordetella)種、およびノカルディア(Nocardia)種か らなる群より抽出される請求の範囲1の方法。 3. ミコバクテリア細胞壁抽出物がミコバクテリウム フレイ(Mycob acterium phlei)から抽出される請求の範囲2の方法。 4. ミコバクテリア細胞壁抽出物が更にグリコサミノグリカン類を含んでな る請求の範囲1の方法。 5. グリコサミノグリカンがヒアルロン酸である請求の範囲4の方法。 6. 油を含まないミコバクテリア細胞壁抽出物の水性懸濁物を含ん でなる免疫刺激化用組成物。 7. 更にグリコサミノグリカン類を含んでなる請求の範囲6の組成物。 8. グリコサミノグリカンがヒアルロン酸である請求の範囲7の組成物。 9. ミコバクテリア細胞壁抽出物が、ミコバクテリウム(Mycobact erium )種、コリネバクテリウム(Corynebacterium)種、 バチレ カルメッテ−グエリン(bacille Calmette−Guer in )(BCG)、コリネバクテリウム パルブム(Corynebacter ium parvum)、コリネホルム(Coryneform)細菌、プロピ オネバクテリウム アクネス(Propionebacterium acne s )(C.パルブム(C.parvum))、ロドコッカス(Rhodococ cus )種、エウバクテリウム(Eubacterium)種、リステリア モ ノサイトゲネス(Listeria monocytogenes)、ボルデテ ラ(Bordetella)種、およびノカルディア(Nocardia)種か らなる群より抽出される請求の範囲6の組成物。 10. ミコバクテリア細胞壁抽出物がミコバクテリウム フレイ(Mycob acterium phlei)から抽出される請求の範囲6の組成物。 11. その組成物を最後に滅菌する請求の範囲6の組成物。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1165593A | 1993-01-29 | 1993-01-29 | |
US011,655 | 1993-01-29 | ||
PCT/CA1994/000054 WO1994016727A1 (en) | 1993-01-29 | 1994-01-28 | Immunotherapeutic composition |
Publications (1)
Publication Number | Publication Date |
---|---|
JPH08508976A true JPH08508976A (ja) | 1996-09-24 |
Family
ID=21751403
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP6516525A Pending JPH08508976A (ja) | 1993-01-29 | 1994-01-28 | 改善化免疫療法用組成物 |
Country Status (11)
Country | Link |
---|---|
US (1) | US5759554A (ja) |
EP (1) | EP0681479B1 (ja) |
JP (1) | JPH08508976A (ja) |
CN (1) | CN1102855C (ja) |
AT (1) | ATE179333T1 (ja) |
AU (1) | AU691797B2 (ja) |
BR (1) | BR9406496A (ja) |
DE (1) | DE69418183T2 (ja) |
DK (1) | DK0681479T3 (ja) |
NZ (1) | NZ261094A (ja) |
WO (1) | WO1994016727A1 (ja) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002531528A (ja) * | 1998-12-04 | 2002-09-24 | バイオニケ ライフ サイエンシーズ インコーポレイテッド | 炎症の治療法 |
JP2008214266A (ja) * | 2007-03-05 | 2008-09-18 | Dainippon Sumitomo Pharma Co Ltd | 細菌細胞壁骨格成分の製造方法 |
JP2014502256A (ja) * | 2010-10-13 | 2014-01-30 | バイオニケ ユロロジー アイピー インコーポレイテッド | 細菌リボ核酸細胞壁組成物並びにこれらを製造および使用する方法 |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AUPO359396A0 (en) * | 1996-11-13 | 1996-12-05 | Amrad Operations Pty. Limited | A method of treatment and pharmaceutical compositions useful for same |
WO1998043655A1 (en) * | 1997-04-02 | 1998-10-08 | Bioniche Inc. | Use of bacterial cell wall extracts for treating topical disorders and wounds |
KR100533576B1 (ko) | 1997-08-05 | 2005-12-05 | 바이오니취 라이프 사이언시즈 인코포레이티드 | 세포증식 및 세포사멸 조절용 조성물 및 방법 |
US6809081B1 (en) * | 1998-12-04 | 2004-10-26 | Bioniche Life Sciences, Inc. | Chemotherapeutic composition and method |
US20020022032A1 (en) * | 1999-04-23 | 2002-02-21 | Curry Patrick Mark | Immuno-adjuvant PDT treatment of metastatic tumors |
WO2001007080A2 (en) * | 1999-07-23 | 2001-02-01 | Bioniche Life Sciences Inc. | Method for enhancing production performance in an animal |
US6890541B1 (en) | 1999-07-23 | 2005-05-10 | Bioniche Life Sciences, Inc. | Method for enhancing production performance in an animal |
CN100445380C (zh) * | 1999-12-13 | 2008-12-24 | 拜昂尼科生命科学有限公司 | 治疗用合成寡核苷酸 |
AU784356B2 (en) | 1999-12-28 | 2006-03-16 | Bioniche Urology Ip Inc. | Hyaluronic acid in the treatment of cancer |
CN1981868A (zh) * | 2000-03-31 | 2007-06-20 | 拜奥根Idec公司 | 抗细胞因子抗体或拮抗剂与抗-cd20在b细胞淋巴瘤治疗中的联合应用 |
TR201101874A2 (tr) | 2011-02-25 | 2011-08-22 | Leyla A�An Nac�Ye | Yüzeyel mesane tümorü tedavisinde kullanılabilecek mycobacterıum(mikobakteri) brumae hücre duvarı ekstreleri. |
WO2015126921A1 (en) * | 2014-02-18 | 2015-08-27 | Advaxis, Inc. | Biomarker directed multi-target immunotherapy |
EP3419638A4 (en) * | 2016-02-25 | 2019-10-02 | Thomas Julius Borody | COMPOSITIONS AND METHOD FOR THE TREATMENT OF CHRONIC INFECTION DISEASES |
IT202000002866A1 (it) | 2020-02-13 | 2021-08-13 | Altergon Sa | Composizioni antivirali |
IT202000002641A1 (it) | 2020-02-11 | 2021-08-11 | Altergon Sa | Composizioni antivirali |
CN113244384A (zh) | 2020-02-11 | 2021-08-13 | 阿尔特刚股份有限公司 | 抗病毒组合物 |
IT202100013292A1 (it) * | 2021-05-21 | 2022-11-21 | Aileens Pharma S R L | Parete cellulare batterica legata a mucopolisaccaride suoi utilizzi e processo per la sua produzione |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3172815A (en) * | 1962-04-24 | 1965-03-09 | Warner Lambert Pharmaceutical | Method for preparing reticulo-endo-thelial system stimulant and stimulant thereof |
US3529057A (en) * | 1964-08-14 | 1970-09-15 | Takeda Chemical Industries Ltd | Purified periodic acid-oxidized mucopeptide of mycobacteria cell walls constituting a vaccine enhancing nonspecific host resistance against pathogenic bacterial infections |
US3331741A (en) * | 1964-12-03 | 1967-07-18 | Warner Lambert Pharmaceutical | Process for the preparation of a soluble bacterial extract |
FR2160326B1 (ja) * | 1971-11-19 | 1975-02-07 | Anvar | |
NL7308450A (ja) * | 1972-06-20 | 1973-12-27 | ||
CH602920A5 (ja) * | 1973-02-23 | 1978-08-15 | Wellcome Found | |
US4069314A (en) * | 1973-02-23 | 1978-01-17 | Christopher Adlam | Glycopeptide extract |
FR2269961B1 (ja) * | 1974-05-06 | 1978-03-24 | Anvar | |
FR2320107A1 (fr) * | 1975-08-05 | 1977-03-04 | Anvar | Nouveaux adjuvants immunologiques, procede pour leur obtention et compositions les contenant |
US4340586A (en) * | 1977-02-18 | 1982-07-20 | Adam Bekierkunst | Pharmaceutical preparation for treating disorders of the skin |
US4503048A (en) * | 1982-06-30 | 1985-03-05 | Ribi Immunochem Research, Inc. | Pyridine soluble extract of a microorganism |
US4505903A (en) * | 1982-06-30 | 1985-03-19 | Ribi Immunochem Research, Inc. | Pyridine soluble extract of a microorganism |
US4504473A (en) * | 1982-06-30 | 1985-03-12 | Ribi Immunochem Research, Inc. | Pyridine soluble extract of a microorganism |
FR2551758B1 (fr) * | 1983-08-16 | 1986-01-31 | Anvar | Derives de muramyl-peptides et de steroides ayant des proprietes d'activation des macrophages |
US4744984A (en) * | 1985-10-08 | 1988-05-17 | Vetrepharm Research, Inc. | Antiviral immunotherapeutic agent and preparation thereof |
FR2662942B1 (fr) * | 1990-06-06 | 1992-09-18 | Neway Tsehay | Medicament immunostimulant a base de glycopeptidolipides polaires de mycobacterium chelonae. |
ATE154759T1 (de) * | 1990-11-08 | 1997-07-15 | Univ London | Mycobacterium als adjuvans für antigene |
-
1994
- 1994-01-28 AT AT94905639T patent/ATE179333T1/de not_active IP Right Cessation
- 1994-01-28 WO PCT/CA1994/000054 patent/WO1994016727A1/en active IP Right Grant
- 1994-01-28 JP JP6516525A patent/JPH08508976A/ja active Pending
- 1994-01-28 CN CN94191293A patent/CN1102855C/zh not_active Expired - Lifetime
- 1994-01-28 DK DK94905639T patent/DK0681479T3/da active
- 1994-01-28 NZ NZ261094A patent/NZ261094A/en not_active IP Right Cessation
- 1994-01-28 BR BR9406496A patent/BR9406496A/pt not_active Application Discontinuation
- 1994-01-28 DE DE69418183T patent/DE69418183T2/de not_active Expired - Lifetime
- 1994-01-28 AU AU59680/94A patent/AU691797B2/en not_active Expired
- 1994-01-28 EP EP94905639A patent/EP0681479B1/en not_active Expired - Lifetime
- 1994-12-09 US US08/352,452 patent/US5759554A/en not_active Expired - Lifetime
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002531528A (ja) * | 1998-12-04 | 2002-09-24 | バイオニケ ライフ サイエンシーズ インコーポレイテッド | 炎症の治療法 |
JP2008214266A (ja) * | 2007-03-05 | 2008-09-18 | Dainippon Sumitomo Pharma Co Ltd | 細菌細胞壁骨格成分の製造方法 |
JP2014502256A (ja) * | 2010-10-13 | 2014-01-30 | バイオニケ ユロロジー アイピー インコーポレイテッド | 細菌リボ核酸細胞壁組成物並びにこれらを製造および使用する方法 |
US9180176B2 (en) | 2010-10-13 | 2015-11-10 | Bioniche Urology Ip Inc. | Bacterial ribonucleic acid cell wall compositions and methods of making and using them |
US9180177B2 (en) | 2010-10-13 | 2015-11-10 | Bioniche Urology Ip Inc. | Bacterial ribonucleic acid cell wall compositions and methods of making and using them |
US9220765B2 (en) | 2010-10-13 | 2015-12-29 | Bioniche Urology Ip Inc. | Bacterial ribonucleic acid cell wall compositions and methods of making and using them |
Also Published As
Publication number | Publication date |
---|---|
AU5968094A (en) | 1994-08-15 |
US5759554A (en) | 1998-06-02 |
EP0681479A1 (en) | 1995-11-15 |
CN1102855C (zh) | 2003-03-12 |
DE69418183D1 (de) | 1999-06-02 |
WO1994016727A1 (en) | 1994-08-04 |
DK0681479T3 (da) | 1999-11-08 |
ATE179333T1 (de) | 1999-05-15 |
CN1118574A (zh) | 1996-03-13 |
AU691797B2 (en) | 1998-05-28 |
DE69418183T2 (de) | 1999-12-16 |
NZ261094A (en) | 1998-04-27 |
BR9406496A (pt) | 1996-01-02 |
EP0681479B1 (en) | 1999-04-28 |
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Legal Events
Date | Code | Title | Description |
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A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20040810 |
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Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20050119 |
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A02 | Decision of refusal |
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