JPH08286155A - Water containing soft lens with superior wearing quality - Google Patents

Water containing soft lens with superior wearing quality

Info

Publication number
JPH08286155A
JPH08286155A JP7088095A JP8809595A JPH08286155A JP H08286155 A JPH08286155 A JP H08286155A JP 7088095 A JP7088095 A JP 7088095A JP 8809595 A JP8809595 A JP 8809595A JP H08286155 A JPH08286155 A JP H08286155A
Authority
JP
Japan
Prior art keywords
lens
thickness
maximum
curve side
curve
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP7088095A
Other languages
Japanese (ja)
Inventor
Tsuneo Hogi
恒夫 保木
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Chemical Industry Co Ltd
Original Assignee
Asahi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Chemical Industry Co Ltd filed Critical Asahi Chemical Industry Co Ltd
Priority to JP7088095A priority Critical patent/JPH08286155A/en
Publication of JPH08286155A publication Critical patent/JPH08286155A/en
Pending legal-status Critical Current

Links

Abstract

PURPOSE: To provide a lens with improved wearing quality by increasing the form maintaining performance of a soft lens with high water content by employing specific lens structure whose peripheral part is shaped matching material characteristics. CONSTITUTION: The soft lens is constituted so that the lens periphery has thickness >=1.2 time as large as the thickness of the center and the position where the lens thickness of each cemented part of a curved surface constituting the lens on a front curve side is maximum is outside the position where the length thickness of the lens at the curved surface cemented part on a base curve side becomes maximum by >=1.01 time. Those lenses are designed so that in general, the thickness of the lens peripheral part is preferably >=1.4 time and more preferably >=1.9 times as large as the center thickness. The position where the lens thickness on the front curve side becomes maximum is outside the position where the lens thickness on the base curve side by preferably 1.02-1.09 and more preferably 1.03-1.08.

Description

【発明の詳細な説明】Detailed Description of the Invention

【0001】[0001]

【産業上の利用分野】本発明は、装用性に優れたレンズ
デザインを有する高含水ソフトレンズに関するものであ
る。更に詳しくいえば、装用時に外れにくく、レンズの
動きが優れ装用感が良い含水率が80%以上の高含水ソ
フトコンタクトレンズに関するものである。
BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a high water content soft lens having a lens design excellent in wearability. More specifically, the present invention relates to a high water content soft contact lens having a water content of 80% or more, which does not easily come off during wearing and has a good lens movement and a good wearing feeling.

【0002】[0002]

【従来の技術】ソフトコンタクトレンズは、含水率が3
8%から80%未満までの含水ソフトコンタクトレンズ
が有り、装用感が優れているところから多く使用されて
いる。また、80%以上の含水率のレンズも提案されて
おり、たとえば、特公昭55−5089号公報、特公昭
62−42487号公報、特公昭62−51447号公
報、特公昭64−11132号公報、特公平4−338
01号公報などにコラーゲンを主成分としたレンズが記
載されている。また、特開平4−340520号公報、
特開平5−45613号公報、特開平5−163384
号公報、特開平5−194603号公報などにグルコマ
ンナンあるいはセルロースを主成分とするレンズが記載
されている。
2. Description of the Related Art Soft contact lenses have a water content of 3
There are 8% to less than 80% hydrous soft contact lenses, and they are often used because of their excellent wearing comfort. A lens having a water content of 80% or more has also been proposed. For example, JP-B-55-5089, JP-B-62-42487, JP-B-62-51447, and JP-B-64-11132. Japanese Patent Examination 4-338
A lens containing collagen as a main component is described in Japanese Patent Publication No. 01, etc. In addition, JP-A-4-340520,
JP-A-5-45613, JP-A-5-163384
JP-A-5-194603 and the like describe lenses containing glucomannan or cellulose as a main component.

【0003】[0003]

【発明が解決しようとする課題】含水率が80%以上の
高含水ソフトコンタクトレンズは室内湿度が少ない時に
はレンズが乾燥してレンズの動きが異常になったり、装
用感が低下したり、外れ易いという問題点があり、一般
に広く使用される所までに至っていない。本発明は、含
水率が高いソフトレンズの形態維持性を高め、装用感を
改良したレンズを提供するものである。
A high water content soft contact lens having a water content of 80% or more causes the lens to dry and the movement of the lens to be abnormal when the indoor humidity is low, the wearing feeling to deteriorate, and the lens tends to come off easily. However, it is not yet widely used. The present invention provides a lens with improved form feeling and improved wearability, while maintaining the shape retention of a soft lens having a high water content.

【0004】[0004]

【課題を解決するための手段】前記課題を解決するた
め、本発明者はソフトコンタクトレンズの材料の材料特
性とレンズデザインとを検討し鋭意研究を重ねた結果、
材料特性に合った特定のレンズ構造にする事でその目的
を達成できることを見いだし、本発明を完成する事がで
きた。すなわち、本発明はソフトコンタクトレンズの周
辺部の形状が特定の構造を有するソフトコンタクトレン
ズに関するものである。
In order to solve the above-mentioned problems, the present inventor has studied the material characteristics of the material of the soft contact lens and the lens design, and as a result of earnest research,
It has been found that the object can be achieved by making a specific lens structure suitable for material characteristics, and the present invention has been completed. That is, the present invention relates to a soft contact lens in which the shape of the peripheral portion of the soft contact lens has a specific structure.

【0005】以下、本発明を詳細に説明する。本発明の
ソフトコンタクトレンズは、レンズ周辺の厚みが中心厚
みの1.2倍以上であり、フロントカーブ側のレンズを
構成する曲面の各接合部でのレンズ厚みが最大となる位
置が、ベースカーブ側の曲面接合部でのレンズ厚みが最
大となる位置より1.01倍以上レンズの外側に位置
し、好ましくは当該接合部でのレンズ厚みがベース側の
曲面接合部よりもフロント側の曲面接合部で厚くなって
いるソフトレンズで、含水率が80%以上の高含水ソフ
トコンタクトレンズである。
The present invention will be described in detail below. In the soft contact lens of the present invention, the thickness around the lens is 1.2 times or more the center thickness, and the position where the lens thickness is the maximum at each joint of the curved surfaces forming the lens on the front curve side is the base curve. The lens is 1.01 times or more outside the lens from the position where the lens thickness at the curved joint on the side is maximum, and preferably the lens thickness at the cemented portion is closer to the front than the curved joint on the base side. It is a soft lens with a thicker part and a high water content soft contact lens with a water content of 80% or more.

【0006】コンタクトレンズの周辺部位が上記構造に
なっていないレンズ、すなわち従来のレンズデザインで
は、乾燥した時にレンズの形状が変わるため、その動き
が変わり、時として装用感が低下し装用できなくなった
り、レンズの外れが起こり易い。本発明のレンズは、レ
ンズ周辺の厚みが中心厚みの1.2倍以上であり、フロ
ントカーブ側のレンズを構成する曲面の各接合部でのレ
ンズ厚みが最大となる位置が、ベースカーブ側の曲面接
合部でのレンズ厚みが最大となる位置より1.01倍以
上レンズの外側に位置している構造を有している。その
当該接合部でのレンズ厚みがベース側の曲面接合部より
もフロント側の曲面接合部で厚くなっているレンズがよ
り好ましい。
In a lens in which the peripheral portion of the contact lens does not have the above structure, that is, in the conventional lens design, the shape of the lens changes when it is dried, so the movement changes, and sometimes the feeling of wearing deteriorates and the lens cannot be worn. , It is easy for the lens to come off. In the lens of the present invention, the thickness of the lens periphery is 1.2 times or more the center thickness, and the position where the lens thickness is maximum at each joint of the curved surfaces forming the lens on the front curve side is on the base curve side. It has a structure which is 1.01 times or more outside the lens from the position where the lens thickness at the curved surface joint becomes maximum. A lens in which the lens thickness at the joint is thicker at the front curved joint than at the base curved joint is more preferable.

【0007】レンズ周辺とはフロント側またはベース側
のオプチカルゾーンよりも外側の部分であり、レンズ周
辺の厚みは厚み計でこの部分を数箇所測定した時の最大
値である。レンズ中心厚みとはオプチカルゾーンの中心
部、一般にはレンズの中心部を厚み計で数箇所測定した
時の最小値である。レンズ周辺部の厚みがレンズ中心部
の厚みの1.2倍未満であると、レンズ表面の乾燥によ
りレンズが変形しやすく、動きの変化、装用感の低下、
レンズの脱落が起こりやすくなり好ましくない。
The lens periphery is a portion outside the optical zone on the front side or the base side, and the thickness of the lens periphery is the maximum value when this portion is measured at several points with a thickness meter. The lens center thickness is the minimum value when the thickness of the center of the optical zone, generally the center of the lens, is measured with a thickness meter. If the thickness of the peripheral portion of the lens is less than 1.2 times the thickness of the central portion of the lens, the lens is likely to be deformed due to drying of the lens surface, which causes a change in movement and a reduction in wearing comfort
The lens is likely to come off, which is not preferable.

【0008】また、フロントカーブ側のレンズを構成す
る曲面の各接合部でのレンズ厚みが最大となる位置が、
ベースカーブ側の曲面接合部でのレンズ厚みが最大とな
る位置の1.01倍未満であるとレンズ表面の乾燥によ
りレンズ形状が著しく変化して、レンズエッジ部が反り
返りやすく、装用感を著しく損ね、レンズの脱落もより
起こりやすく好ましくない。また、その当該接合部での
レンズ厚みがベース側の曲面接合部よりもフロント側の
曲面接合部で厚くなっていないと、レンズが反転し易く
装用時にレンズのエッジがめくれたり、取り扱い中にレ
ンズが反転し易く、反転しても識別が出来にくいため誤
って裏返してレンズを装用する危険性が大きい。
Further, the position where the lens thickness is maximum at each joint of the curved surfaces forming the lens on the front curve side is
If it is less than 1.01 times the position where the lens thickness at the curved surface on the base curve side is the maximum, the lens shape will change drastically due to the drying of the lens surface, and the lens edge part tends to warp and the wearing comfort will be significantly impaired. However, the lens is more likely to come off, which is not preferable. If the lens thickness at the joint is not thicker at the front side curved joint than at the base side curved joint, the lens is easy to invert and the edge of the lens may be flipped up during wearing, or the lens may be damaged during handling. Since it is easy to reverse and it is difficult to identify even if it is reversed, there is a great risk of accidentally turning it over and wearing the lens.

【0009】なお、レンズ周辺の厚みが0.5mmを超
えて厚くなったり、レンズエッジ先端の厚みが0.2m
mを超えて厚くなると装用感が低下するため、一般的に
はレンズ周辺の厚みが0.5mm未満、レンズエッジ周
辺の厚みが0.2mm未満になる様にデザインされる。
これらレンズのデザインは、レンズの径、パワー等によ
って変わり、一義的には決められないが、一般的には、
レンズ周辺の厚みが中心厚みの1.4倍以上であるもの
が好ましく、1.9倍以上であるものがより好ましい。
また、フロントカーブ側のレンズを構成する局面の各接
合部でのレンズ厚みが最大となる位置がベースカーブ側
の曲面接合部でのレンズ厚みが最大となる位置より1.
02以上1.09倍未満であるものが好ましく、1.0
3倍以上1.08倍未満のものがより好ましい。
The thickness around the lens exceeds 0.5 mm, and the thickness at the tip of the lens edge is 0.2 m.
When the thickness exceeds m, the wearing feeling deteriorates. Therefore, it is generally designed so that the thickness around the lens is less than 0.5 mm and the thickness around the lens edge is less than 0.2 mm.
The design of these lenses varies depending on the diameter and power of the lens and cannot be uniquely determined, but in general,
The thickness around the lens is preferably 1.4 times or more the center thickness, and more preferably 1.9 times or more.
Further, the position where the lens thickness is maximum at each cemented portion on the front curve side lens forming surface is 1.
It is preferably 02 or more and less than 1.09 times, and 1.0
It is more preferably 3 times or more and less than 1.08 times.

【0010】本発明の特定の構造を有するレンズデザイ
ンは、例えば、レンズサイズ13.5mm、ベベル幅約
0.7mm、エッジリフト量0.10mm、中心厚み
0.10mm、周辺部最大厚み0.19mm(BCとベ
ベル接合部)、フロント側での曲面接合部の最大厚み
0.193mm(径13.0mmの位置)、ベースカー
ブ(BC)8.60mm、フロントカーブ(FC)8.
625mm、キャリアカーブ(CC)9.46mmのレ
ンチキュラーレンズである。このレンズは、レンズの動
きが良く、レンズ表面からの水の蒸発による乾燥が起き
ても動きは変わらず、レンズの脱落も無い。
A lens design having a specific structure of the present invention has, for example, a lens size of 13.5 mm, a bevel width of about 0.7 mm, an edge lift amount of 0.10 mm, a center thickness of 0.10 mm, and a peripheral maximum thickness of 0.19 mm. (BC and bevel joint), maximum thickness of curved joint on front side 0.193 mm (position with diameter 13.0 mm), base curve (BC) 8.60 mm, front curve (FC) 8.
It is a lenticular lens of 625 mm and carrier curve (CC) 9.46 mm. This lens has a good lens movement and does not change even if drying occurs due to water evaporation from the lens surface, and the lens does not fall off.

【0011】レンズの寸法の内曲率半径は、高含水ソフ
トレンズの場合にはレンズを直接測定する事は困難であ
り、上記寸法はレンズを形成するキャスト成形の鋳型で
の寸法を記した。なお、レンズの径、厚みは、万能投影
器、読み取り顕微鏡あるいは実体顕微鏡などを使用して
レンズそのままあるいは切断片を観察して測定できる。
本発明のレンズの材料は、ソフトレンズに適したポリマ
ーであれば天然あるいは合成のものが使用できるが、含
水率が約98から38%の含水ポリマーが好ましい。装
用時の感触が優れるところから含水率が80%以上であ
るポリマーがより好ましい。
The inner radius of curvature of the dimension of the lens is difficult to directly measure the lens in the case of a high water content soft lens, and the above dimension is the dimension in the cast mold for forming the lens. The diameter and thickness of the lens can be measured by observing the lens itself or a cut piece using a universal projector, a reading microscope or a stereoscopic microscope.
As the material of the lens of the present invention, a natural or synthetic material can be used as long as it is a polymer suitable for a soft lens, but a water-containing polymer having a water content of about 98 to 38% is preferable. A polymer having a water content of 80% or more is more preferable because it has an excellent feel when worn.

【0012】上記のポリマーとして、例えば、グルコマ
ンナン、カラギーナン、寒天、キサンタンガム、ローカ
ストビーンガム、ジュランガム、可溶化コラーゲン、フ
ァイバーコラーゲン、ゼラチン、キトサン、ポリビニー
ルアルコールゲルから選ばれた親水性高分子化合物を主
成分とするなどがある。これらの親水性ポリマーにグラ
フト共重合可能なモノマーを共重合したもの、アシル
化、エステル化、サクシニル化、メチル化など変性した
もの、紫外線照射、電離性放射線照射などにより架橋し
たものなどがも使用できる。本発明のコンタクトレンズ
は、従来のレンズ製造方法で製造でき、例えば、ポリマ
ーのブロックから旋盤で切削して研磨加工する方法、レ
ンズの形状に相当する重合鋳型の中にモノマー組成物を
注入して重合するキャスト法、あるいは、レンズの片面
のみを重合鋳型でキャスト重合して形成し他の面を切削
研磨法で仕上げる方法などがある。
As the above-mentioned polymer, for example, a hydrophilic polymer compound selected from glucomannan, carrageenan, agar, xanthan gum, locust bean gum, duran gum, solubilized collagen, fiber collagen, gelatin, chitosan, polyvinyl alcohol gel is used. There are things such as the main component. Also used are those obtained by copolymerizing graft copolymerizable monomers with these hydrophilic polymers, those modified by acylation, esterification, succinylation, methylation, etc., and those crosslinked by UV irradiation, ionizing radiation irradiation, etc. it can. The contact lens of the present invention can be manufactured by a conventional lens manufacturing method, for example, a method of cutting from a polymer block with a lathe and polishing, a method of injecting a monomer composition into a polymerization mold corresponding to the shape of the lens. There is a casting method of polymerizing, or a method of casting and polymerizing only one surface of a lens with a polymerization template and finishing the other surface by a cutting and polishing method.

【0013】[0013]

【実施例】以下、本発明を実施例で詳細に説明する。EXAMPLES The present invention will be described in detail below with reference to examples.

【0014】[0014]

【実施例1】グルコマンナン粉末(粘度110000c
ps、清水化学(株)製、商品名プロポールPA)0.2
6g、キサンタンガム0.08g、ローカストビーンガ
ム0.03gを、精製水42gに均一に溶解させた。次
いで約90℃に加熱後、減圧脱法しさらに遠心分離して
透明な上澄み液を分取した。この混合溶液にグルコマン
ナンに対して1.25%の炭酸ナトリウムを加え混合し
た。この溶液を、直径13.50mm、ベースカーブ
8.60mm、ベベルカーブ9.80mm、ベベル幅
0.725mm、フロントカーブ8.625mm、フロ
ントオプチカルゾーン径9.60mm、キャリアカーブ
9.46mmのレンズパワー−0.00、中心厚み0.
10mm、レンズエッジ厚み0.10のコンタクトレン
ズを鋳型重合できるポリプロピレン製の鋳型に注入し、
−7℃で凍結した後室温で解凍する操作を8回繰り返し
てゲル化させて、さらに80℃で1時間加熱してゲル化
を終了させ透明なレンズを得た。
Example 1 Glucomannan powder (viscosity 110000c
ps, Shimizu Chemical Co., Ltd., trade name Propol PA) 0.2
6 g, xanthan gum 0.08 g, and locust bean gum 0.03 g were uniformly dissolved in purified water 42 g. Then, after heating to about 90 ° C., the mixture was decompressed and further centrifuged to collect a transparent supernatant. To this mixed solution, 1.25% sodium carbonate based on glucomannan was added and mixed. This solution was used for lens power of diameter 13.50 mm, base curve 8.60 mm, bevel curve 9.80 mm, bevel width 0.725 mm, front curve 8.625 mm, front optical zone diameter 9.60 mm, carrier curve 9.46 mm. 0.00, center thickness 0.
A contact lens of 10 mm and a lens edge thickness of 0.10 is poured into a polypropylene mold capable of mold polymerization,
The procedure of freezing at −7 ° C. and then thawing at room temperature was repeated 8 times to cause gelation, and heating was further performed at 80 ° C. for 1 hour to complete gelation and obtain a transparent lens.

【0015】得られたレンズの含水率は95%で、レン
ズの中心部で切断した断面を万能投影器で20倍猪以上
に拡大して測定した各部の厚みは、中心厚み0.10m
m、周辺の最大厚み0.192mm(FC側キャリアカ
ーブとエッジカーブの接合部、約12.5mm径の位
置)、ベースカーブとベベルカーブの接合部(約12.
0mm径の位置)の厚みは約0.188mmであった。
レンズは透明な弾力性に富むもので、形態維持性にも優
れ、レンズを反転させても元に復元した。PMMAで製
作したモデル眼にレンズをはめて、表面の乾燥によるレ
ンズの形状変化を評価した結果、5分後でも脱落は認め
られなかった。また、レンズを上下に移動させてもレン
ズは安定しており、レンズの動きもスムーズであった。
The water content of the obtained lens was 95%, and the thickness of each portion measured by enlarging the cross section cut at the central portion of the lens by a universal projector 20 times or more was a central thickness of 0.10 m.
m, the maximum thickness of the periphery is 0.192 mm (the joint between the FC side carrier curve and the edge curve, the position of about 12.5 mm diameter), the joint between the base curve and the bevel curve (about 12.
The thickness at the 0 mm diameter position) was about 0.188 mm.
The lens is transparent and highly elastic, and has excellent shape retention. The lens was fitted to a model eye made of PMMA, and the shape change of the lens due to surface drying was evaluated. As a result, no dropout was observed even after 5 minutes. The lens was stable even when it was moved up and down, and the movement of the lens was smooth.

【0016】[0016]

【実施例2】ファイバーコラーゲン(牛の腱由来)をク
エン酸溶液中で膨潤し3%の分散液とした。また、脱脂
したアテロコラーゲン(子牛の皮由来)をクエン酸中に
溶解し7%の透明な溶液とし、上記のファイバーコラー
ゲン溶液と1対1で混合した。この溶液を10分間真空
下に置き脱気した後、実施例1で使用したプラスチック
製レンズ鋳型に注入した。鋳型を閉止後、窒素雰囲気下
でコバルト60でガンマー線を15kGy照射した。成
形レンズを鋳型から剥離後、燐酸−食塩水のph=7.
2緩衝液中で中性化し、次いで0.9%生理食塩水中に
浸漬して保管した。出来上がったコラーゲンレンズは含
水率約95%で、中心厚み0.10mm、周辺の最大厚
み0.19mm(FC側キャリアカーブとエッジカーブ
の接合部、約12.5mm径の位置)、ベースカーブと
ベベルカーブの接合部(約12.0mm径の位置)の厚
みは約0.185mmであった。レンズは透明な弾力性
に富むもので、形態維持性にも優れ、レンズを反転させ
ても元に復元した。PMMAで製作したモデル眼にレン
ズをはめて、表面の乾燥によるレンズの形状変化を評価
した結果、5分後でも脱落は認められなかった。また、
レンズを上下に移動させてもレンズは安定しており、レ
ンズの動きもスムーズであった。
Example 2 Fiber collagen (derived from bovine tendon) was swollen in a citric acid solution to prepare a 3% dispersion liquid. Further, defatted atelocollagen (derived from calf skin) was dissolved in citric acid to obtain a 7% transparent solution, which was mixed 1: 1 with the above fiber collagen solution. This solution was placed under vacuum for 10 minutes to be deaerated, and then poured into the plastic lens mold used in Example 1. After closing the mold, gamma rays of 15 kGy were irradiated with cobalt 60 in a nitrogen atmosphere. After peeling the molded lens from the mold, phosphoric acid-saline solution ph = 7.
It was neutralized in 2 buffer solution and then immersed in 0.9% physiological saline and stored. The finished collagen lens has a water content of about 95%, a center thickness of 0.10 mm, a maximum peripheral thickness of 0.19 mm (the FC side carrier curve and edge curve joint, a position of about 12.5 mm diameter), a base curve and a bevel curve. The thickness of the joint portion (at a position of a diameter of about 12.0 mm) was about 0.185 mm. The lens is transparent and highly elastic, and has excellent shape retention. The lens was fitted to a model eye made of PMMA, and the shape change of the lens due to surface drying was evaluated. As a result, no dropout was observed even after 5 minutes. Also,
The lens was stable even when it was moved up and down, and the movement of the lens was smooth.

【0017】[0017]

【実施例3】ファイバーコラーゲン(牛の腱由来)をク
エン酸溶液中で膨潤し3%の分散液とした。また、脱脂
したアテロコラーゲン(子牛の皮由来)をクエン酸中に
溶解し7%の透明な溶液とした。この溶液にN−イソプ
ロピルアクリルアミド1.98%N、N'−メチレンビ
スアクリルアミド0.02%を添加して均一に溶解さ
せ、上記のファイバーコラーゲン溶液と1対1で混合し
た。この溶液を10分間真空下に置き脱気し窒素ガスで
置換した後、実施例1で使用したプラスチック製レンズ
鋳型に注入した。鋳型を閉止後、窒素雰囲気下でコバル
ト60でガンマー線を12kGy照射した。成形レンズ
を鋳型から剥離後、燐酸−食塩水のph=7.2緩衝液
中で中性化し、次いで0.9%生理食塩水中に浸漬して
保管した。出来上がった変性コラーゲンレンズは含水率
約94%で、中心厚み0.11mm、周辺の最大厚み
0.192mm(FC側キャリアカーブとエッジカーブ
の接合部、約12.5mm径の位置)、ベースカーブと
ベベルカーブの接合部(約12.0mm径の位置)の厚
みは約0.188mmであった。レンズは透明な弾力性
に富むもので、形態維持性にも優れ、レンズを反転させ
ても元に復元した。PMMAで製作したモデル眼にレン
ズをはめて、表面の乾燥によるレンズの形状変化を評価
した結果、5分後でも脱落は認められなかった。また、
レンズを上下に移動させてもレンズは安定しており、レ
ンズの動きもスムーズであった。
Example 3 Fiber collagen (derived from bovine tendon) was swollen in a citric acid solution to obtain a 3% dispersion liquid. Also, defatted atelocollagen (from calf skin) was dissolved in citric acid to give a 7% clear solution. To this solution, 1.98% N-isopropylacrylamide and 0.02% N'-methylenebisacrylamide were added and uniformly dissolved, and mixed 1: 1 with the above fiber collagen solution. This solution was placed under vacuum for 10 minutes to be deaerated and replaced with nitrogen gas, and then poured into the plastic lens mold used in Example 1. After closing the mold, it was irradiated with gamma rays of 12 kGy with cobalt 60 in a nitrogen atmosphere. The molded lens was peeled from the mold, neutralized in a phosphoric acid-saline solution pH = 7.2 buffer, and then immersed in 0.9% physiological saline for storage. The finished denatured collagen lens has a water content of about 94%, a central thickness of 0.11 mm, a peripheral maximum thickness of 0.192 mm (the joint between the FC side carrier curve and the edge curve, a position of about 12.5 mm diameter), and a base curve. The thickness of the joint portion of the bevel curve (position at a diameter of about 12.0 mm) was about 0.188 mm. The lens is transparent and highly elastic, and has excellent shape retention. The lens was fitted to a model eye made of PMMA, and the shape change of the lens due to surface drying was evaluated. As a result, no dropout was observed even after 5 minutes. Also,
The lens was stable even when it was moved up and down, and the movement of the lens was smooth.

【0018】[0018]

【比較例1】実施例2で使用したものと同じコラーゲン
溶液を、直径13.50mm、ベースカーブ8.60m
m、ベベルカーブ9.80mm、ベベル幅0.725m
m、フロントカーブ8.625mm、フロントオプチカ
ルゾーン径12.50mm、キャリアカーブ9.25m
mのレンズパワー−0.00、中心厚み0.20mm、
レンズエッジ厚み0.10のコンタクトレンズを鋳型重
合できるポリプロピレン製の鋳型に注入し、実施例2と
同じ方法でガンマー線照射した。得られたレンズは形態
維持性に劣り、ピンセットで保存液から引き上げると丸
まってしまい、指先にレンズを乗せると形が崩れ、装用
出来る状態でなかった。
Comparative Example 1 The same collagen solution used in Example 2 was used, with a diameter of 13.50 mm and a base curve of 8.60 m.
m, bevel curve 9.80 mm, bevel width 0.725 m
m, front curve 8.625mm, front optical zone diameter 12.50mm, carrier curve 9.25m
m lens power -0.00, center thickness 0.20 mm,
A contact lens having a lens edge thickness of 0.10 was poured into a polypropylene mold capable of mold polymerization, and was irradiated with gamma rays in the same manner as in Example 2. The obtained lens was inferior in shape retention, curled up when pulled up from the storage solution with tweezers, and lost its shape when the lens was placed on the fingertip, and was not in a state where it could be worn.

【0019】[0019]

【発明の効果】本発明のソフトコンタクトレンズは、パ
ワーが小さいレンズでもその形態維持性が優れているた
め取り扱いしやすく、レンズの動きがスムーズで安定し
ており、レンズの脱落が無く、装用性に優れたコンタク
トレンズを提供する。ローパワーレンズでの形態維持性
が優れているため、特にコラーゲンレンズを治療用に使
用するために有用なコンタクトレンズを提供する。
EFFECTS OF THE INVENTION The soft contact lens of the present invention is easy to handle because the shape maintaining property is excellent even for a lens having a small power, the movement of the lens is smooth and stable, and the lens does not fall off and is easy to wear. To provide excellent contact lenses. Provided is a contact lens which is particularly useful for therapeutic use of a collagen lens because of its excellent shape retention in a low power lens.

Claims (4)

【特許請求の範囲】[Claims] 【請求項1】 レンズ周辺の厚みが中心厚みの1.2倍
以上であり、フロントカーブ側のレンズを構成する曲面
の各接合部でのレンズ厚みが最大となる位置が、ベース
カーブ側の曲面接合部でのレンズ厚みが最大となる位置
より1.01倍以上レンズの外側に位置しているソフト
レンズ。
1. The base curve side curved surface is a position where the thickness of the lens periphery is 1.2 times or more the center thickness and the lens thickness is maximum at each joint of the curved surfaces forming the lens on the front curve side. A soft lens that is 1.01 times or more outside the lens where the lens thickness at the junction is maximum.
【請求項2】 レンズ厚みの最大値がフロント側の曲面
接合部にある特許請求項1に記載の含水ソフトレンズ。
2. The water-containing soft lens according to claim 1, wherein the maximum value of the lens thickness is at the curved surface joint portion on the front side.
【請求項3】含水率が80%以上である特許請求項1及
び2に記載の含水ソフトレンズ。
3. The water-containing soft lens according to claim 1, which has a water content of 80% or more.
【請求項4】 レンズ材料がグルコマンナン、カラギー
ナン、寒天、キサンタンガム、ジュランガム、コラーゲ
ン、ゼラチン、キトサン、ポリビニールアルコールゲル
から選ばれた親水性高分子化合物を主成分とする、特許
請求項1〜3に記載の含水ソフトレンズ。
4. The lens material is mainly composed of a hydrophilic polymer compound selected from glucomannan, carrageenan, agar, xanthan gum, duran gum, collagen, gelatin, chitosan and polyvinyl alcohol gel. The water-containing soft lens described in.
JP7088095A 1995-04-13 1995-04-13 Water containing soft lens with superior wearing quality Pending JPH08286155A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP7088095A JPH08286155A (en) 1995-04-13 1995-04-13 Water containing soft lens with superior wearing quality

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7088095A JPH08286155A (en) 1995-04-13 1995-04-13 Water containing soft lens with superior wearing quality

Publications (1)

Publication Number Publication Date
JPH08286155A true JPH08286155A (en) 1996-11-01

Family

ID=13933321

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7088095A Pending JPH08286155A (en) 1995-04-13 1995-04-13 Water containing soft lens with superior wearing quality

Country Status (1)

Country Link
JP (1) JPH08286155A (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1316836A1 (en) * 2001-11-30 2003-06-04 Menicon Co., Ltd. Contact lens and method of designing the same
JP2017149708A (en) * 2016-02-23 2017-08-31 多木化学株式会社 Fibrotic collagen crosslinked membrane capable of suture
JP2017149814A (en) * 2016-02-23 2017-08-31 多木化学株式会社 Surface-worked collagen molded body
JP2020055916A (en) * 2018-09-28 2020-04-09 Spiber株式会社 Mold molded body, manufacturing method of mold molded body, and flexibility adjustment method of mold molded body

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1316836A1 (en) * 2001-11-30 2003-06-04 Menicon Co., Ltd. Contact lens and method of designing the same
US6726323B2 (en) 2001-11-30 2004-04-27 Menicon Co., Ltd. Contact lens and method of designing the same
JP2017149708A (en) * 2016-02-23 2017-08-31 多木化学株式会社 Fibrotic collagen crosslinked membrane capable of suture
JP2017149814A (en) * 2016-02-23 2017-08-31 多木化学株式会社 Surface-worked collagen molded body
JP2020055916A (en) * 2018-09-28 2020-04-09 Spiber株式会社 Mold molded body, manufacturing method of mold molded body, and flexibility adjustment method of mold molded body

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