JPH07116260A - Catheter for medical treatment and its production - Google Patents
Catheter for medical treatment and its productionInfo
- Publication number
- JPH07116260A JPH07116260A JP5268898A JP26889893A JPH07116260A JP H07116260 A JPH07116260 A JP H07116260A JP 5268898 A JP5268898 A JP 5268898A JP 26889893 A JP26889893 A JP 26889893A JP H07116260 A JPH07116260 A JP H07116260A
- Authority
- JP
- Japan
- Prior art keywords
- tube
- catheter
- tip
- plasticizer
- distal end
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Materials For Medical Uses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Abstract
Description
【０００１】[0001]
【産業上の利用分野】本発明は、柔軟性の異なる部分を
有する医療用カテーテルとその作製方法に関する。更に
詳しくは、本発明は、例えば薄肉血管造影用カテーテ
ル、誘導用カテーテル、血管形成用カテーテル、尿路用
カテーテル、胃腸病学用カテーテルなどの医療用カテー
テル、及びこのようなカテーテルの作製方法に関するも
のである。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a medical catheter having portions having different flexibility and a method for producing the same. More specifically, the present invention relates to medical catheters such as thin-wall angiography catheters, guiding catheters, angioplasty catheters, urinary tract catheters, catheters for gastroenterology, and methods for producing such catheters. Is.
【０００２】[0002]
【従来の技術】血管等の体内管腔内に挿入して使用され
るカテーテルは、様々な組織に傷を付けたり、引き裂い
たりして外傷を与えることなく、体内の離れたところに
ある部位まで到達しなければならないので、カテーテル
の先端部分は、本体や遠位端部の隣接部分に比べてより
軟質で外傷を与えないようなものでることが必要で、柔
軟性のある遠位端部を備えることが望ましい。2. Description of the Related Art A catheter used by inserting it into a lumen of a body such as a blood vessel can be used to damage various tissues or tore it up to a distant part of the body without causing trauma. Because it must be reached, the tip of the catheter must be softer and less atraumatic than the body and adjacent to the distal end, and the flexible distal end It is desirable to prepare.
【０００３】特に記載しない限り、本明細書において
「遠位端部」とは、そのカテーテルを使用している医者
または他の医療関係者から最も遠いところに位置する、
カテーテルの先端側にある部分または区域を意味する。
「中遠位端部」とは、カテーテルの最先端まで延長しな
い遠位端部の一部を指す。「先端」とは、カテーテルの
最も遠位の端部を指す。Unless otherwise noted, the term "distal end" as used herein is located furthest from the physician or other medical personnel using the catheter,
The portion or area on the distal side of the catheter.
"Mid-distal end" refers to the portion of the distal end that does not extend to the very tip of the catheter. "Tip" refers to the most distal end of the catheter.
【０００４】例えば、血管を通過して冠状動脈口に挿入
される必要のあるような血管造影カテーテルは、血管の
内面や心臓の小葉状弁などの他の組織に傷を付けてはい
けない。従って、外傷の危険を減らすために、このよう
なカテーテルは本体及び中遠位端部が上記基準に該当
し、同時に先端または先端部分がより柔軟性を有するこ
とが望ましい。このようにそれぞれの部分が異なった特
性を有するカテーテルの必要性が主張されてきたと同時
に、このようなカテーテルを複数の部分を融合させて作
った場合、カテーテルの先端部が使用中に脱落するとい
う危険性も指摘されて来た。For example, angiographic catheters that need to be inserted through the blood vessel and into the ostium of the coronary artery should not damage the inner surface of the blood vessel or other tissues such as the leaflet of the heart. Therefore, in order to reduce the risk of trauma, it is desirable for such a catheter to meet the above criteria for the body and the mid-distal end while at the same time being more flexible at the tip or tip portion. While the need for catheters with different properties in each part has been argued, it is said that when such a catheter is made by fusing multiple parts, the tip of the catheter falls off during use. The danger has also been pointed out.
【０００５】このような問題を解決するため、本出願人
は先に、カテーテルを構成する重合体材料内に多量の可
塑剤を吸収させることによって遠位端部や先端部分を軟
質化し、本体部分と一体に形成されていて先端部が剥離
して脱落することのない医療用カテーテルの発明をな
し、特開平５−６４６６０号公報に開示した。In order to solve such a problem, the present applicant has first made the distal end portion and the tip portion soften by absorbing a large amount of the plasticizer in the polymer material forming the catheter, and the main body portion An invention of a medical catheter which is integrally formed with and whose tip does not peel off and fall off is disclosed in Japanese Patent Laid-Open No. 5-64660.
【０００６】しかし、このカテーテルで可塑剤を吸収さ
せる接触工程では、膨張剤としてチューブ材料の重合体
に対する良溶媒を使用しているため、接触している間、
可塑剤の含浸と重合体の溶解が併行して進行する。従っ
て、高濃度の可塑剤量を含浸させようとすれば、チュー
ブ表面の溶解劣化が防げず、原型を留めない変形、或い
はチューブ内面のケバ立ち劣化が発生してしまう等の問
題があり、可塑剤含浸による軟質化には限界があった。
また、体内組織を一番傷付け易い先端開口部はそのチュ
ーブ壁の角を削り落とすが、チューブ壁の厚みの範囲で
しか角を削り落とすことはできないので、非外傷性の先
端を得るには不十分であった。However, since the good solvent for the polymer of the tube material is used as the swelling agent in the contact step of absorbing the plasticizer with this catheter, the
Impregnation of the plasticizer and dissolution of the polymer proceed concurrently. Therefore, if an attempt is made to impregnate a high-concentration amount of plasticizer, there is a problem that dissolution deterioration of the tube surface cannot be prevented, deformation that does not hold the prototype, or fluffing deterioration of the inner surface of the tube occurs. There was a limit to the softening by the agent impregnation.
In addition, the tip opening that is most likely to damage the body tissue scrapes off the corner of the tube wall, but since it can be scraped off only within the range of the thickness of the tube wall, it is not suitable for obtaining an atraumatic tip. Was enough.
【０００７】[0007]
【発明が解決しようとする課題】本発明は、従来のカテ
ーテルのこのような問題点を解決するため、種々の検討
の結果なされたもので、その目的とするところはカテー
テル先端部分をより柔軟化し、その形状も含めて非外傷
性を改善したカテーテルを提供するにある。SUMMARY OF THE INVENTION The present invention has been made as a result of various studies in order to solve the above problems of the conventional catheter, and the purpose thereof is to make the catheter tip portion more flexible. , And to provide a catheter having improved atraumatic properties including its shape.
【０００８】[0008]
【課題を解決するための手段】即ち本発明は、ポリアミ
ドもしくはポリウレタン重合体材料の細長いチューブか
らなり、該チューブの少なくとも遠位端部が可塑剤の含
浸により軟質化処理されたカテーテルであって、遠位端
部の先端部近傍を肉薄化すると共に、先端周縁部をチュ
ーブの中心に向かって絞り込み、先端部を丸め加工した
ことを特徴とする医療用カテーテルである。SUMMARY OF THE INVENTION The present invention is a catheter comprising an elongated tube of polyamide or polyurethane polymer material, at least the distal end of which is softened by impregnation with a plasticizer. The medical catheter is characterized in that the distal end portion of the distal end portion is thinned, the peripheral edge portion of the distal end portion is narrowed toward the center of the tube, and the distal end portion is rounded.
【０００９】また第２に、ポリアミドもしくはポリウレ
タン重合体材料の細長いチューブの先端部分を、柔軟な
ものにするため重合体材料の良溶媒からなる膨張剤とそ
の膨張剤に可溶で高分子量低移動性の可塑剤との混合液
に浸して、膨張及び軟質化させた後、その膨張した外周
部分をセンターレスグラインダーで研削して肉薄にし、
さらに、その先端部分の形状を非外傷性なものとするた
めに、肉薄にした先端周縁部を回転している加熱金型に
押し当てて、チューブの中心に向かって絞り込むことに
よって、先端部を丸め加工することを特徴とする医療用
カテーテルの作製方法である。Secondly, a swelling agent made of a good solvent for the polymer material in order to make the end portion of the elongated tube of the polyamide or polyurethane polymer material flexible, and a swelling agent soluble in the swelling agent and having a high molecular weight and low migration rate. After dipping in a mixed liquid with a flexible plasticizer to expand and soften it, grind the expanded outer peripheral part with a centerless grinder to make it thin,
Furthermore, in order to make the shape of the tip part atraumatic, the thinned tip peripheral edge part is pressed against the rotating heating die and narrowed down toward the center of the tube, It is a method for producing a medical catheter characterized by being rolled.
【００１０】以下、図面により本発明を詳細に説明す
る。次に述べる本発明の好ましい実施態様は、非融合形
の３区域からなる壁の薄い血管造影用カテーテル、及び
そのようなカテーテルを作製する方法に関するものであ
るが、本発明はこれに限定されるものではない。本発明
は、他の医療用カテーテル、例えば、バルーンカテーテ
ルなどや、誘導用カテーテル、血管形成用カテーテル、
尿路用カテーテル、胃腸病学用カテーテルなど、２箇所
以上の柔らかさまたは柔軟性の異なった部分を必要とす
る一般的なカテーテルにも使用される。The present invention will be described in detail below with reference to the drawings. The preferred embodiments of the invention described below relate to a non-fusion, three-section thin-wall angiography catheter and a method of making such a catheter, although the invention is not limited thereto. Not a thing. The present invention provides another medical catheter, for example, a balloon catheter, a guiding catheter, an angioplasty catheter,
It is also used for general catheters such as urinary tract catheters and catheters for gastroenterology, which require two or more portions having different softness or flexibility.
【００１１】図１は本発明の一実施例となる血管造影用
カテーテルの一部を切り取った図で、（ａ）は斜視図、
（ｂ）は縦断面図であり、本体部分（３）、及び遠位端
部（５）（中遠位端部（７）と、チューブの最も遠位に
位置する非外傷性の先端部分（６）に別れる）で構成さ
れる細長い非融合形重合体チューブ（１）からなる、３
区域血管造影用カテーテル（２）を示す。チューブ
（１）の手元側端部には、ハブ部材（４）が固定されて
いる。図１（ｂ）に示されるように、縦方向の内腔
（９）は、細長い非融合形の重合体チューブ（１）を通
り、ハブ部材（４）の同軸の穴（１０）から本体部分
（３）を通り、中遠位端部（７）、先端部分（６）を通
って先端部分にある開口部（８）まで延びている。FIG. 1 is a partially cutaway view of an angiographic catheter according to an embodiment of the present invention, in which (a) is a perspective view,
(B) is a longitudinal cross-sectional view showing the body portion (3) and the distal end portion (5) (middle-distal end portion (7) and the atraumatic tip portion (6) located at the most distal end of the tube. 3) comprising an elongated non-fusion type polymer tube (1) composed of
1 shows a segmental angiography catheter (2). A hub member (4) is fixed to the proximal end of the tube (1). As shown in FIG. 1 (b), the longitudinal lumen (9) passes through the elongated non-fusion polymer tube (1) from the coaxial bore (10) of the hub member (4) to the body portion. It extends through (3), through the mid-distal end (7), the tip portion (6) to the opening (8) in the tip portion.
【００１２】図１（ｂ）は図１（ａ）の縦断面図で、そ
の先端部分（６）のチューブ肉厚は本体部分のそれより
肉薄となっており、開口部（８）はチューブ中心に向か
って絞り込まれている。チューブ（１）の先端部分
（６）を軟質化する工程で膨張剤と可塑剤との混合液に
浸して膨張、軟質化させ乾燥すると、チューブの先端部
分（６）は図２（ａ）に示すように大きく膨張すると共
に、内腔も拡張する。この膨張した外周部分を機械的に
切削して、元の外径に戻したのが図２（ｂ）である。こ
のようにして軟質化された先端部分（６）を肉薄にする
ことで、より柔軟性の大きい先端部分を得ることが出来
る。更に、開口部（８）は、肉薄の先端部を図３に示す
ような金型を用いて丸め加工することで、大きな半径の
丸みを付けることが出来、血管壁を傷付けたりしない非
外傷性の形状とすることが出来る。FIG. 1 (b) is a longitudinal sectional view of FIG. 1 (a), in which the tube wall thickness of the tip portion (6) is thinner than that of the main body portion, and the opening portion (8) has the tube center. Is narrowed towards. When the tip portion (6) of the tube (1) is softened in the step of softening it so as to expand, soften and dry it, the tip portion (6) of the tube becomes as shown in FIG. It expands significantly as shown, and also expands the lumen. FIG. 2B shows that the expanded outer peripheral portion is mechanically cut to restore the original outer diameter. By thinning the softened tip portion (6) in this manner, a tip portion having greater flexibility can be obtained. Furthermore, the opening (8) can be rounded with a large radius by rounding the thin front end using a mold as shown in FIG. 3, and is atraumatic without damaging the blood vessel wall. Can be in the shape of.
【００１３】本発明による先端部分の柔軟化は、可塑剤
含浸と先端部の肉薄化との相乗効果により成せるもので
ある。可塑剤含浸だけによる軟質化ではない為より柔軟
な先端部が得られ、しかも外観は劣化しない。また、柔
軟部が同一チューブからなる為、血管造影中異物の発生
がなく安全性の高いカテーテルを、安価で容易に製造す
ることが出来る。そして先端開口部も大きな半径で丸め
加工することが出来、先端部の柔軟性と相まって体内組
織と接触する先端開口部が特に非外傷性となる。The softening of the tip portion according to the present invention can be achieved by a synergistic effect of impregnation with a plasticizer and thinning of the tip portion. A softer tip is obtained because it is not softened only by impregnation with a plasticizer, and the appearance does not deteriorate. In addition, since the flexible portion is made of the same tube, a highly safe catheter that does not generate foreign matter during angiography can be easily manufactured at low cost. The tip opening can also be rounded with a large radius, and the tip opening that comes into contact with body tissue becomes particularly atraumatic in combination with the flexibility of the tip.
【００１４】[0014]
【実施例】以下、実施例により本発明をさらに具体的に
説明するが、これらは本発明を限定するものではない。
先ず、フランス規格寸法６の外径（２．０ｍｍ）と壁の
厚さ０．３ｍｍを有する、ナイロン１１のカテーテル用
チューブを押出成形した。そのチューブを１００ｃｍの
長さに切ってワイヤーマンドレルの上に被せ、遠位端部
５ｃｍを冷たい流水に浸し、チューブの残りの部分は熱
い空気（１４０℃）に３０分間曝す。このチューブをオ
ーブンと水から取り出し、得られた２領域からなるチュ
ーブの先端部分０．３５ｃｍを、９９％蟻酸にＮ−ベン
ゼンスルホニル−ｎ−ブチルアミンを溶解した。６０℃
の暖かい溶液に１０分間浸すと、チューブの先端は約１
０〜３０％膨張した。得られた３種類の硬さを有するチ
ューブを該溶液から取り出し、２％アンモニア水に１分
間浸して残留蟻酸を中和した。このチューブを室温で乾
燥すると、先端部は図２（ａ）のような形状になる。次
いで、膨張した先端部分を、チューブ表面を研磨できる
センターレスグラインダーを用いて元の外径まで研磨す
る。これで先端部の肉厚が０．２ｍｍに薄くなり、図２
（ｂ）のような形状になる。EXAMPLES The present invention will be described in more detail below with reference to examples, but these do not limit the present invention.
First, a nylon 11 catheter tube having an outer diameter (2.0 mm) of French standard size 6 and a wall thickness of 0.3 mm was extruded. The tube is cut to a length of 100 cm, covered over a wire mandrel, the distal end 5 cm is immersed in cold running water, and the rest of the tube is exposed to hot air (140 ° C.) for 30 minutes. This tube was taken out of the oven and water, and 0.35 cm of the tip portion of the obtained two-region tube was dissolved in N-benzenesulfonyl-n-butylamine in 99% formic acid. 60 ° C
After immersing in warm solution for 10 minutes, the tip of the tube will be about 1
Swelled 0-30%. The obtained tubes having three kinds of hardness were taken out of the solution and immersed in 2% aqueous ammonia for 1 minute to neutralize the residual formic acid. When this tube is dried at room temperature, the tip has a shape as shown in FIG. Next, the expanded tip portion is ground to the original outer diameter using a centerless grinder capable of polishing the tube surface. This reduces the thickness of the tip to 0.2 mm.
The shape is as shown in (b).
【００１５】最後に肉薄の先端を、回転数１０００ＲＰ
Ｍで回転している、温度１５５℃に加熱した図３に示す
ような金型（１１）に押し当て先端部を丸め加工した。
使用した金型（１１）は、お椀状の凹みの中央に円錐形
の突き出しがあり、チューブの先端部を円錐形の突き出
しに被せるようにして、お椀状の凹みに入れ、金型（１
１）に押し当てる。その先端部分が可塑剤と肉薄化によ
って柔軟化されていて、熱に敏感で脆弱な構造であるか
らチューブの先端部はお椀状の凹みの内壁に沿って、中
心の円錐形の突き出しに向かって絞り込まれるような形
になり、丸め加工が完成する。Finally, the thin tip is rotated at a rotation speed of 1000 RP.
The tip was rounded by pressing it against a mold (11) rotating at M and heated to a temperature of 155 ° C. as shown in FIG.
The mold (11) used has a conical protrusion in the center of the bowl-shaped recess, and the tip of the tube is covered with the cone-shaped protrusion, and the mold (11) is inserted into the mold (1
Press on 1). Due to its heat-sensitive and fragile structure, the tip of which is softened by plasticizer and thinning, the tip of the tube follows the inner wall of the bowl-shaped recess toward the central conical protrusion. It becomes a shape that is narrowed down and the rounding process is completed.
【００１６】[0016]
【発明の効果】本発明によれば、従来、可塑剤の含浸だ
けでは十分に軟質化できなかった先端部分を、膨張した
先端部分を機械的な切削により肉薄にすることで柔軟性
を高めて、十分な柔軟性を得ると共に、先端開口部を加
熱金型に押し当てて丸め加工をすることで非外傷性のカ
テーテルとすることが出来るので、患者の体内に挿入し
て施術を行っているときに様々な組織に損傷を与えるこ
とがなく、医療用カテーテルとして極めて有用である。According to the present invention, it is possible to improve flexibility by thinning the expanded tip portion by mechanical cutting, which has been conventionally difficult to soften only by impregnating a plasticizer. , Atraumatic catheter can be obtained by pressing the tip opening against a heating mold and rounding it while obtaining sufficient flexibility, so it is inserted into the patient's body for treatment. Sometimes it does not damage various tissues and is extremely useful as a medical catheter.
【図１】本発明の一実施例となる血管造影用カテーテル
の一部を切り取った図で、（ａ）は斜視図、（ｂ）は縦
断面図である。FIG. 1 is a view in which a part of an angiographic catheter according to an embodiment of the present invention is cut away, (a) is a perspective view, and (b) is a longitudinal sectional view.
【図２】本発明における先端部の肉薄化の方法を説明す
るための図である。FIG. 2 is a diagram for explaining a method of thinning the tip portion in the present invention.
【図３】本発明における先端部の丸め加工の方法を説明
するための図である。FIG. 3 is a diagram for explaining a method of rounding a tip portion according to the present invention.
１ チューブ ２ カテーテル ３ 本体部分 ４ ハブ部材 ５ 遠位端部 ６ 先端部分 ７ 中遠位端部 ８ 開口部 ９ 内腔 １０ 穴 １１ 金型 1 Tube 2 Catheter 3 Body Part 4 Hub Member 5 Distal End Part 6 Tip Part 7 Middle Distal End Part 8 Opening Part 9 Lumen 10 Hole 11 Mold
Claims (2)
材料の細長いチューブからなり、該チューブの少なくと
も遠位端部が可塑剤の含浸により軟質化処理されたカテ
ーテルであって、遠位端部の先端部近傍を肉薄化すると
共に、先端周縁部をチューブの中心に向かって絞り込
み、先端部を丸め加工したことを特徴とする医療用カテ
ーテル。1. A catheter comprising an elongated tube of a polyamide or polyurethane polymer material, at least the distal end of which is softened by impregnation with a plasticizer, the distal end of which is located near the tip. A medical catheter characterized in that it is thinned and the tip peripheral portion is narrowed toward the center of the tube, and the tip portion is rounded.
材料の細長いチューブの先端部分を、膨張剤と可塑剤と
の混合液に浸して膨張、軟質化させ、膨張した外周部分
をセンターレスグラインダーにて研削することにより肉
薄化させ、さらに、その先端周縁部を回転している加熱
金型に押し当てて、先端部を丸め加工することを特徴と
する医療用カテーテルの作製方法。2. An elongated tube made of a polyamide or polyurethane polymer material is soaked in a mixed liquid of an expanding agent and a plasticizer to expand and soften it, and the expanded outer peripheral part is ground by a centerless grinder. A method for producing a medical catheter, characterized in that the tip is rounded by pressing the peripheral edge of the tip against a rotating heating die to make the tip round.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5268898A JPH07116260A (en) | 1993-10-27 | 1993-10-27 | Catheter for medical treatment and its production |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5268898A JPH07116260A (en) | 1993-10-27 | 1993-10-27 | Catheter for medical treatment and its production |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH07116260A true JPH07116260A (en) | 1995-05-09 |
Family
ID=17464807
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP5268898A Pending JPH07116260A (en) | 1993-10-27 | 1993-10-27 | Catheter for medical treatment and its production |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH07116260A (en) |
Cited By (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007512087A (en) * | 2003-11-24 | 2007-05-17 | フローカルディア， インコーポレイテッド | Steerable ultrasound catheter |
| JP2015513483A (en) * | 2012-02-23 | 2015-05-14 | ホリスター・インコーポレイテッドＨｏｌｌｉｓｔｅｒ Ｉｎｃｏｒｐｏｒａｔｅｄ | Method and apparatus for providing a catheter tip to a multilayer tube |
| US10004520B2 (en) | 2004-08-26 | 2018-06-26 | Flowcardia, Inc. | Ultrasound catheter devices and methods |
| US10111680B2 (en) | 2002-08-02 | 2018-10-30 | Flowcardia, Inc. | Therapeutic ultrasound system |
| US10130380B2 (en) | 2003-02-26 | 2018-11-20 | Flowcardia, Inc. | Ultrasound catheter apparatus |
| US10537712B2 (en) | 2006-11-07 | 2020-01-21 | Flowcardia, Inc. | Ultrasound catheter having improved distal end |
| US10582983B2 (en) | 2017-02-06 | 2020-03-10 | C. R. Bard, Inc. | Ultrasonic endovascular catheter with a controllable sheath |
| US10758256B2 (en) | 2016-12-22 | 2020-09-01 | C. R. Bard, Inc. | Ultrasonic endovascular catheter |
| US10835267B2 (en) | 2002-08-02 | 2020-11-17 | Flowcardia, Inc. | Ultrasound catheter having protective feature against breakage |
| US11191554B2 (en) | 2012-01-18 | 2021-12-07 | C.R. Bard, Inc. | Vascular re-entry device |
| US11344750B2 (en) | 2012-08-02 | 2022-05-31 | Flowcardia, Inc. | Ultrasound catheter system |
| US11426189B2 (en) | 2003-09-19 | 2022-08-30 | Flowcardia, Inc. | Connector for securing ultrasound catheter to transducer |
| US11510690B2 (en) | 2005-01-20 | 2022-11-29 | Flowcardia, Inc. | Vibrational catheter devices and methods for making same |
| US11596726B2 (en) | 2016-12-17 | 2023-03-07 | C.R. Bard, Inc. | Ultrasound devices for removing clots from catheters and related methods |
| US11633206B2 (en) | 2016-11-23 | 2023-04-25 | C.R. Bard, Inc. | Catheter with retractable sheath and methods thereof |
-
1993
- 1993-10-27 JP JP5268898A patent/JPH07116260A/en active Pending
Cited By (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10111680B2 (en) | 2002-08-02 | 2018-10-30 | Flowcardia, Inc. | Therapeutic ultrasound system |
| US10835267B2 (en) | 2002-08-02 | 2020-11-17 | Flowcardia, Inc. | Ultrasound catheter having protective feature against breakage |
| US10722262B2 (en) | 2002-08-02 | 2020-07-28 | Flowcardia, Inc. | Therapeutic ultrasound system |
| US10285727B2 (en) | 2002-08-26 | 2019-05-14 | Flowcardia, Inc. | Steerable ultrasound catheter |
| US10130380B2 (en) | 2003-02-26 | 2018-11-20 | Flowcardia, Inc. | Ultrasound catheter apparatus |
| US11103261B2 (en) | 2003-02-26 | 2021-08-31 | C.R. Bard, Inc. | Ultrasound catheter apparatus |
| US11426189B2 (en) | 2003-09-19 | 2022-08-30 | Flowcardia, Inc. | Connector for securing ultrasound catheter to transducer |
| JP4805841B2 (en) * | 2003-11-24 | 2011-11-02 | フローカルディア， インコーポレイテッド | Steerable ultrasound catheter |
| US11109884B2 (en) | 2003-11-24 | 2021-09-07 | Flowcardia, Inc. | Steerable ultrasound catheter |
| JP2007512087A (en) * | 2003-11-24 | 2007-05-17 | フローカルディア， インコーポレイテッド | Steerable ultrasound catheter |
| US10682151B2 (en) | 2004-08-26 | 2020-06-16 | Flowcardia, Inc. | Ultrasound catheter devices and methods |
| US10004520B2 (en) | 2004-08-26 | 2018-06-26 | Flowcardia, Inc. | Ultrasound catheter devices and methods |
| US11510690B2 (en) | 2005-01-20 | 2022-11-29 | Flowcardia, Inc. | Vibrational catheter devices and methods for making same |
| US10537712B2 (en) | 2006-11-07 | 2020-01-21 | Flowcardia, Inc. | Ultrasound catheter having improved distal end |
| US11229772B2 (en) | 2006-11-07 | 2022-01-25 | Flowcardia, Inc. | Ultrasound catheter having improved distal end |
| US11191554B2 (en) | 2012-01-18 | 2021-12-07 | C.R. Bard, Inc. | Vascular re-entry device |
| JP2015513483A (en) * | 2012-02-23 | 2015-05-14 | ホリスター・インコーポレイテッドＨｏｌｌｉｓｔｅｒ Ｉｎｃｏｒｐｏｒａｔｅｄ | Method and apparatus for providing a catheter tip to a multilayer tube |
| US11344750B2 (en) | 2012-08-02 | 2022-05-31 | Flowcardia, Inc. | Ultrasound catheter system |
| US11633206B2 (en) | 2016-11-23 | 2023-04-25 | C.R. Bard, Inc. | Catheter with retractable sheath and methods thereof |
| US11596726B2 (en) | 2016-12-17 | 2023-03-07 | C.R. Bard, Inc. | Ultrasound devices for removing clots from catheters and related methods |
| US10758256B2 (en) | 2016-12-22 | 2020-09-01 | C. R. Bard, Inc. | Ultrasonic endovascular catheter |
| US10582983B2 (en) | 2017-02-06 | 2020-03-10 | C. R. Bard, Inc. | Ultrasonic endovascular catheter with a controllable sheath |
| US11638624B2 (en) | 2017-02-06 | 2023-05-02 | C.R. Bard, Inc. | Ultrasonic endovascular catheter with a controllable sheath |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPH07116260A (en) | Catheter for medical treatment and its production | |
| US4551292A (en) | Method for making a catheter with a soft, deformable tip | |
| US5484565A (en) | Method for making a medical catheter | |
| JP3383009B2 (en) | Vascular catheter | |
| US8617193B2 (en) | Balloon catheter with improved pushability | |
| JPH10216237A (en) | Stylet and device including the stylet | |
| JPH031026B2 (en) | ||
| CN110947082B (en) | Balloon guiding catheter and preparation method thereof | |
| CN111419338A (en) | Balloon suction catheter device for intracranial thrombus removal | |
| US6719774B1 (en) | Method for forming low profile balloon and low profile balloon for use with a catheter | |
| WO2011139878A1 (en) | Balloon with integral segmented dilation elements | |
| JP3436996B2 (en) | Medical catheter and method of manufacturing the same | |
| JP2002143318A (en) | Assembly of introducing catheter and catheter for diagnosis and medical treatment | |
| JPS59141957A (en) | Stay cathetel and production thereof | |
| JPH0898892A (en) | Expansion catheter and its production | |
| JP2004350901A (en) | Method for forming guide wire insertion opening | |
| CN212700034U (en) | Balloon suction catheter device for intracranial thrombus removal | |
| JP2592784Y2 (en) | Medical guidewire | |
| CN220025863U (en) | Nick sacculus | |
| CN218923530U (en) | Cutting balloon catheter | |
| JPH07308383A (en) | Catheter | |
| JPH11114069A (en) | Catheter | |
| JPH08257132A (en) | Medical guide wire | |
| CA2070252C (en) | A polymeric article such as a medical catheter and method for making the same | |
| JPH06121828A (en) | Medical balloon catheter |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20050221 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20061205 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20061212 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20070406 |