JPH06320021A - Pipet device - Google Patents
Pipet deviceInfo
- Publication number
- JPH06320021A JPH06320021A JP13098793A JP13098793A JPH06320021A JP H06320021 A JPH06320021 A JP H06320021A JP 13098793 A JP13098793 A JP 13098793A JP 13098793 A JP13098793 A JP 13098793A JP H06320021 A JPH06320021 A JP H06320021A
- Authority
- JP
- Japan
- Prior art keywords
- tip
- diameter
- seal member
- tip portion
- pipette device
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Sampling And Sample Adjustment (AREA)
- Devices For Use In Laboratory Experiments (AREA)
Abstract
Description
【０００１】[0001]
【産業上の利用分野】本発明は新規なピペット装置に関
する。詳しくは、圧力制御により液体をチップ部内に吸
引し又は採取した液体をチップ部外に排出するピペット
装置において、チップ部の交換を容易に行うことができ
るようにした新規なピペット装置を提供しようとするも
のである。FIELD OF THE INVENTION The present invention relates to a novel pipetting device. Specifically, in a pipette device that sucks a liquid into the tip portion or discharges a collected liquid to the outside of the tip portion by pressure control, it is an object of the present invention to provide a novel pipette device capable of easily exchanging the tip portion. To do.
【０００２】[0002]
【従来の技術】容器内に収納された液体を指定量だけ吸
引した後、採取した液体のうちの指定量分を別の容器に
移す所謂分注作業においては、ピペット装置が用いられ
る。2. Description of the Related Art A pipette device is used in a so-called dispensing operation in which a specified amount of the collected liquid is transferred to another container after a specified amount of the liquid contained in the container is sucked.
【０００３】即ち、ピペット装置は、その先端部に設け
られた管状のチップ部を容器内の液体に漬けてからチッ
プ部内を負圧にすることによって液体を吸い上げ、その
後別の容器内にチップ部を移送して加圧することによっ
てチップ部内の液体を排出するように構成される。That is, in a pipette device, a tubular tip portion provided at its tip is submerged in a liquid in a container, and a negative pressure is applied to the inside of the tip portion to suck up the liquid, and then the tip portion is placed in another container. The liquid in the chip portion is discharged by transferring and pressurizing the liquid.
【０００４】そして、チップ部をピペット装置の被挿合
部に取り付ける際には、チップ部を被挿合部の端部に外
挿するとともに、両者の隙間を通してエアーの出入りが
生じないように気密にするためにシール部材（Ｏリング
等）が両部材の間隙をシールするために設けられる。When the tip portion is attached to the inserted portion of the pipette device, the tip portion is externally attached to the end portion of the inserted portion and airtight so that air does not come in and out through the gap between them. A seal member (O-ring or the like) is provided to seal the gap between the two members.
【０００５】[0005]
【発明が解決しようとする課題】ところで、従来のピペ
ット装置にあっては、チップ部の着脱作業が煩わしく、
また、チップ部に余計な力をかけてしまうとチップ部の
形状がくずれ易いという問題がある。By the way, in the conventional pipette device, the attaching and detaching work of the tip portion is troublesome,
Further, if an excessive force is applied to the tip portion, the shape of the tip portion tends to collapse.
【０００６】これは、チップ部を被挿合部に外挿する際
にシール部材をつぶして密着性を高めるのにある程度の
力を必要とするためであり、チップ部の取り付けや取り
外しに充分に気を付けねばならず、また、特殊な工具を
使ったり作業に対する高い習熟度を要することになる。This is because a certain amount of force is required to squeeze the seal member to enhance the adhesiveness when the tip portion is externally attached to the mating portion, and is sufficient for attaching and detaching the tip portion. You need to be careful, and you need to have a high level of proficiency with special tools and work.
【０００７】また、チップ部の取り付け時に力加減を誤
るとチップ部の内径を押し拡げる結果となり内径の拡大
によりシール部材が所期の効果を奏しなくなり気密性が
損なわれるという不都合や、チップ部のうち被挿合部に
取り付けられる部分が変形してしまい再利用することが
できなくなる等の不都合がある。Further, if the force is wrongly applied when mounting the tip portion, the inner diameter of the tip portion is pushed and expanded, resulting in the disadvantage that the sealing member does not exert the intended effect due to the increase of the inner diameter and the airtightness is impaired. Of these, there is a disadvantage that the portion attached to the inserted portion is deformed and cannot be reused.
【０００８】[0008]
【課題を解決するための手段】そこで、本発明ピペット
装置は、上記した問題を解決するために、チップ部と該
チップ部が挿合される被挿合部との間に生じる隙間をシ
ールするためにシール部材を設け、該シール部材を拡径
手段によって変形させることによってシール部材とチッ
プ部との密着度を高めるようにしたものである。Therefore, in order to solve the above problems, the pipette device of the present invention seals a gap formed between a tip portion and an inserted portion into which the tip portion is inserted. For this purpose, a seal member is provided, and the seal member is deformed by the diameter expanding means to enhance the degree of adhesion between the seal member and the tip portion.
【０００９】[0009]
【作用】本発明ピペット装置によれば、チップ部を被挿
合部に軽く挿合しておいてから、シール部材を拡径手段
によって変形させることによってシール部材とチップ部
との密着度を高め、シールが確実となるようにしている
ため、チップ部に無理な力をかけることなくチップ部を
被挿合部に容易に取り付けることができる。According to the pipette device of the present invention, the tip portion is lightly inserted into the insertion portion, and then the sealing member is deformed by the diameter expanding means to enhance the adhesion between the sealing member and the tip portion. Since the seal is ensured, the tip portion can be easily attached to the mating portion without applying excessive force to the tip portion.
【００１０】つまり、チップ部を被挿合部に取り付ける
際にチップ部でシール部材を変形させることによってチ
ップ部と被挿合部との間のシールを行うのではなく、チ
ップ部を被挿合部に軽く挿合させておいてから拡径手段
によってシール部材を変形させてこれを内側からチップ
部に圧接させることでチップ部と被挿合部との間のシー
ルとチップ部の保持とを両立させることができる。That is, when the chip portion is attached to the mating portion, the seal member is not deformed to seal the tip portion and the mated portion, but the chip portion is mated. After being lightly inserted into the portion, the seal member is deformed by the diameter expanding means and pressed against the tip portion from the inside to seal between the tip portion and the inserted portion and to hold the tip portion. It can be compatible.
【００１１】[0011]
【実施例】以下に、本発明ピペット装置の詳細を図示し
た実施例に従って説明する。The details of the pipetting apparatus of the present invention will be described below with reference to the illustrated embodiments.
【００１２】図１はピペット装置１の構造を原理的に示
すものである。FIG. 1 shows the structure of the pipette device 1 in principle.
【００１３】２はピペット装置１の主部であり、その一
端部２ａが被挿合部とされて管状のチップ部３がこの部
分に着脱自在に取り付けられるようになっている。Reference numeral 2 is a main portion of the pipette device 1, and one end portion 2a of the pipette device 1 is a portion to be inserted, and a tubular tip portion 3 is detachably attached to this portion.
【００１４】主部２にはチップ部３に連通する連通孔２
ｂが形成されており、該連通孔２ｂは加減圧装置４に接
続されている。The main portion 2 has a communicating hole 2 communicating with the tip portion 3.
b is formed, and the communication hole 2b is connected to the pressurizing / depressurizing device 4.
【００１５】加減圧装置４としては、例えば、図示する
ようにシリンダ５と該シリンダ５内に設けられたピスト
ン６とを有し、モータ等の駆動手段７によってピストン
６を移動させることによってシリンダ５の内圧を可変す
る機構等を用いることができる。The pressurizing / depressurizing device 4 has, for example, a cylinder 5 and a piston 6 provided in the cylinder 5 as shown in the figure, and the cylinder 5 is moved by moving the piston 6 by a driving means 7 such as a motor. It is possible to use a mechanism or the like for varying the internal pressure of the.
【００１６】チップ部３はこれを主部２の被挿合部２ａ
に外挿することによって取り付けられるようになってお
り、両者間のシールのためにシール部材８が介挿されて
いる。The tip portion 3 is formed by inserting the tip portion 3 into the inserted portion 2a of the main portion 2.
It is attached by being externally attached to a seal member 8, and a seal member 8 is interposed for sealing between the two.
【００１７】９は拡径手段であり、シール部材８をチッ
プ部３の内壁に強く密着させるために設けられている。Reference numeral 9 denotes a diameter expanding means, which is provided for strongly adhering the seal member 8 to the inner wall of the tip portion 3.
【００１８】図ではシール部材８としてＯリングを用い
た例を示しており、拡径手段９によりＯリングの内径を
大きくすることによってＯリングの外周部をチップ部３
の内壁に圧接させてチップ部３の保持とシール性を保証
するようになっている。The figure shows an example in which an O-ring is used as the seal member 8. By enlarging the inner diameter of the O-ring by the diameter expansion means 9, the outer peripheral portion of the O-ring is replaced by the tip portion 3.
The tip portion 3 is pressure-contacted with the inner wall to ensure the retention and sealing of the tip portion 3.
【００１９】尚、シール部材８にはＯリングの他、例え
ば、ゴム筋を用いることができ、この場合にはエアーを
供給する（つまり、拡径手段９に空気圧を利用する）こ
とでゴム筋を膨張させてその一部をチップ部３の内壁に
圧接させるようにする方法等を挙げることができる。In addition to the O-ring, for example, a rubber streak can be used as the seal member 8. In this case, the rubber stirrup is obtained by supplying air (that is, air pressure is used for the diameter expanding means 9). Can be expanded so that a part thereof is pressed against the inner wall of the tip portion 3.
【００２０】ピペット装置１は、図示しない移送手段に
よって水平面内の移動制御や上下方向の移動制御が行わ
れるようになっている。The pipette device 1 is adapted to be controlled to move in a horizontal plane and to be moved vertically by a transfer means (not shown).
【００２１】例えば、ピペット装置１をロボットアーム
の先端部に取り付けることによって、液体の吸引時や排
出時におけるピペット装置１の位置決め制御を行うこと
ができるようになっている。For example, by attaching the pipette device 1 to the tip of the robot arm, it is possible to perform positioning control of the pipette device 1 when sucking or discharging the liquid.
【００２２】１０は液体１１が収容された容器である。Reference numeral 10 is a container containing a liquid 11.
【００２３】しかして、ピペット装置１において、先ず
チップ部３の一端部を主部２の被挿合部２ａに外挿す
る。この状態ではチップ部３が被挿合部２ａに緩やかに
挿合されているにすぎず、その後拡径手段９によりシー
ル部材８を変形させることによってシール部材８の一部
をチップ部３の内壁に密着させ、チップ部３を保持する
とともに、チップ部３と被挿合部２ａとの間にエアーの
出入りが生じないようにシールする。Then, in the pipette device 1, first, one end of the tip portion 3 is externally fitted to the fitted portion 2a of the main portion 2. In this state, the tip portion 3 is merely gently inserted into the inserted portion 2a, and thereafter, the seal member 8 is deformed by the diameter-expanding means 9 so that a part of the seal member 8 is partially covered with the inner wall of the tip portion 3. The tip portion 3 is held in close contact with the tip portion 3 and is sealed so that air does not enter and leave between the tip portion 3 and the inserted portion 2a.
【００２４】次にピペット装置１の位置決め制御によっ
てチップ部３の先端部を容器１０内の液体１１に漬け、
加減圧装置４によりチップ部３内を負圧にして液体１１
の一部を吸引する。Next, the tip portion of the tip portion 3 is immersed in the liquid 11 in the container 10 by the positioning control of the pipette device 1,
The pressurizing / depressurizing device 4 makes the inside of the tip portion 3 into a negative pressure, so
Aspirate some of.
【００２５】その後、ピペット装置１を移動してチップ
部３を別の容器内に位置させ、加減圧装置４によりチッ
プ部３内を加圧して、採取した液体の一部をチップ部３
外に排出する。After that, the pipette device 1 is moved to position the tip portion 3 in another container, and the inside of the tip portion 3 is pressurized by the pressurizing / depressurizing device 4, so that a part of the collected liquid is put into the tip portion 3
Discharge to the outside.
【００２６】尚、液体の採取量や排出量が指定した量に
なるように制御するのは加減圧装置４の圧力制御によっ
て行う。例えば、シリンダ５とピストン６を使った場合
にはピストン６の移動量をその駆動手段７により制御す
れば良い。The control of the liquid collection amount and the liquid discharge amount to the designated amount is performed by the pressure control of the pressurizing / depressurizing device 4. For example, when the cylinder 5 and the piston 6 are used, the movement amount of the piston 6 may be controlled by the driving means 7.
【００２７】図２乃至図６はピペット装置の具体例１Ａ
を示すものであり、加減圧装置としてシリンダとピスト
ンを有する機構を用いるとともに、シール部材としてＯ
リングを用い空気圧を利用した拡径機構を採用したもの
である。2 to 6 show a concrete example 1A of the pipette device.
And a mechanism having a cylinder and a piston is used as a pressure increasing / decreasing device, and O is used as a seal member.
It uses a ring to expand the diameter using air pressure.
【００２８】図２はピペット装置１Ａを示すものであ
る。FIG. 2 shows a pipette device 1A.
【００２９】１２はピペット装置１Ａの主部であり、金
属により形成されている。Reference numeral 12 denotes a main part of the pipette device 1A, which is made of metal.
【００３０】１３はシリンダであり、主部１２内に形成
されており、該シリンダ１３がピストン１４とともに加
減圧装置を構成している。Reference numeral 13 denotes a cylinder, which is formed inside the main portion 12 and which together with the piston 14 constitutes a pressure increasing / decreasing device.
【００３１】主部１２の下端面には凹部１５が形成され
ており、また、主部１２の下端寄りの部分には筒部１６
の上端部が外嵌固定されている。A concave portion 15 is formed in the lower end surface of the main portion 12, and a cylindrical portion 16 is formed in the portion near the lower end of the main portion 12.
The upper end of the is externally fitted and fixed.
【００３２】尚、筒部１６の内径は下端寄りの部分で小
さく、これより上側の部分で稍大きくなっており、これ
によって上向きの段差面１６ａが形成されている。The inner diameter of the tubular portion 16 is small in the portion near the lower end and slightly larger in the upper portion, thereby forming an upward step surface 16a.
【００３３】１７は金属製のチップシャフトであり、貫
通孔１７ａを有する管状の部材として形成されており、
その上端寄りの部分が主部１２に固定されている。Reference numeral 17 is a metal tip shaft, which is formed as a tubular member having a through hole 17a,
The portion near the upper end is fixed to the main portion 12.
【００３４】そして、その下端寄りの部分１７ｂがその
他の部分に比して大径とされており、これに後述するチ
ップ部が挿合される。また、この被挿合部１７ｂの上端
には上方を向いた環状の凹部１７ｃとこれを囲む突壁１
７ｄが形成されている。A portion 17b near the lower end has a larger diameter than the other portions, and a tip portion described later is inserted therein. Further, an annular concave portion 17c facing upward and a projecting wall 1 surrounding the concave portion 17c are formed at the upper end of the inserted portion 17b.
7d is formed.
【００３５】尚、チップシャフト１７の貫通孔１７ａは
主部１２に形成された連通孔１２ａを介してシリンダ１
３に繋がっている。The through hole 17a of the tip shaft 17 is connected to the cylinder 1 through the communication hole 12a formed in the main portion 12.
It is connected to 3.
【００３６】１８は合成樹脂により管状に形成されたチ
ップ部であり、その上端寄りの部分がチップシャフト１
７の被挿合部１７ｂに外挿されるようになっている。Reference numeral 18 is a tip portion formed of a synthetic resin in a tubular shape, and a portion near the upper end thereof is the tip shaft 1
It is adapted to be externally inserted into the inserted portion 17b of No. 7.
【００３７】チップ部１８の上端部１８ａはその外径が
他の部分の外径に比して大きくされている。The outer diameter of the upper end portion 18a of the tip portion 18 is larger than the outer diameters of the other portions.
【００３８】そして、チップ部１８の下端部１８ｂは先
細りとされており、この部分が液体内に浸漬されること
になる。The lower end portion 18b of the tip portion 18 is tapered, and this portion is immersed in the liquid.
【００３９】１９はチップシャフト１７に摺動可能に外
挿された拡径部材であり、金属により略筒状に形成され
ている。Reference numeral 19 denotes a diameter-expanding member slidably fitted on the tip shaft 17, and is formed of metal into a substantially cylindrical shape.
【００４０】拡径部材１９はその上端寄りの部分１９ａ
が他の部分に比して大径とされ、該部分１９ａの上端部
が主部２の凹部１５内に摺動可能な状態で受け入れられ
ている。The expanding member 19 has a portion 19a near the upper end thereof.
Has a larger diameter than other parts, and the upper end of the part 19a is slidably received in the recess 15 of the main part 2.
【００４１】また、拡径部材１９の下端寄りの部分は図
３乃至図６に示すようにその外径が下方にいくに従って
小さくされ、これによってテーパー部１９ｂが形成され
ており、その下端部１９ｃは最小、かつ、一定の外径を
有する部分とされている。Further, as shown in FIGS. 3 to 6, the outer diameter of the portion of the diameter-expanding member 19 near the lower end is made smaller as the outer diameter thereof goes downward, thereby forming the tapered portion 19b, and the lower end portion 19c thereof. Is a portion having a minimum and constant outer diameter.
【００４２】２０はＯリングであり、チップ部１８の上
端部１８ａの内壁と拡径部材１９の下端寄りの部分との
間に設けられている。尚、チップシャフト１７の突壁１
７ｄが拡径部材１９の下降に伴うＯリング２０の下降に
対してストッパーの役目を果たしている。An O-ring 20 is provided between the inner wall of the upper end portion 18a of the tip portion 18 and the portion of the expanding member 19 near the lower end. In addition, the projecting wall 1 of the tip shaft 17
7d serves as a stopper against the lowering of the O-ring 20 accompanying the lowering of the diameter expanding member 19.
【００４３】２１は金属製の筒状をしたチップ抜き部材
であり、拡径部材１９と上記した筒部１６との間に摺動
可能な状態で設けられている。Reference numeral 21 denotes a metal-made tubular chip extracting member, which is slidably provided between the diameter-expanding member 19 and the above-mentioned tubular portion 16.
【００４４】チップ抜き部材２１はその下端面２１ａを
チップ部１８の上端部１８ａに当接させることによって
チップ部１８の上端部１８ａをチップシャフト１７から
抜き出すために用いられる。The tip removing member 21 is used to extract the upper end portion 18a of the tip portion 18 from the tip shaft 17 by bringing the lower end surface 21a thereof into contact with the upper end portion 18a of the tip portion 18.
【００４５】チップ抜き部材２１には上記拡径部材１９
の大径部１９ａを受け入れるための上端に開口した凹部
２２が形成されており、その下端部を除く部分２２ａの
内径が拡径部材１９の大径部１９ａの外径に略等しく、
下端部２２ｂの内径はこれより径が大きくなっている。The tip removing member 21 has the diameter expanding member 19 described above.
Is formed with a recessed portion 22 at the upper end for receiving the large diameter portion 19a, and the inner diameter of the portion 22a excluding the lower end portion is substantially equal to the outer diameter of the large diameter portion 19a of the diameter expansion member 19,
The inner diameter of the lower end portion 22b is larger than this.
【００４６】そして、この凹部２２と主部１２の凹部１
５とによって形成される空間をシリンダとし、拡径部材
１９の大径部１９ａをピストンとするエアーシリンダ２
３の構成が用いられている。Then, the concave portion 22 and the concave portion 1 of the main portion 12
An air cylinder 2 in which the space formed by 5 and 5 is a cylinder, and the large diameter portion 19a of the diameter expanding member 19 is a piston.
3 configurations are used.
【００４７】即ち、チップ部１８装着用のエアー管２４
が主部１２の側面に取り付けられており、主部１２内に
形成された孔２５を通してエアー管２４と凹部１５とが
連通されている。That is, the air pipe 24 for mounting the tip portion 18
Is attached to the side surface of the main portion 12, and the air pipe 24 and the recess 15 are communicated with each other through a hole 25 formed in the main portion 12.
【００４８】また、チップ部１８の取り外し用のエアー
管２６が設けられ、その先端部が筒部１６の側面に形成
された長孔１６ｂを通してチップ抜き部材２１の側面に
固定されており、エアー管２６とチップ抜き部材２１の
凹部２２とが連通されている。Further, an air pipe 26 for removing the tip portion 18 is provided, and the tip end thereof is fixed to the side surface of the tip removing member 21 through a long hole 16b formed in the side surface of the cylinder portion 16. 26 and the recess 22 of the tip removing member 21 communicate with each other.
【００４９】従って、エアー管２４、２６を介した空圧
制御により凹部１５内の圧力を高めると拡径部材１９が
下降し、逆に凹部２２内の圧力を高めると拡径部材１９
が上昇することになる。Therefore, when the pressure in the recess 15 is increased by air pressure control via the air pipes 24, 26, the diameter expanding member 19 is lowered, and conversely, when the pressure in the recess 22 is increased, the diameter expanding member 19 is increased.
Will rise.
【００５０】また、チップ抜き部材２１はエアー管２６
を介した空圧制御により下降されるようになっている。The tip removing member 21 is an air pipe 26.
It is designed to be lowered by air pressure control via.
【００５１】つまり、拡径部材１９が上死点に達した後
もエアー管２６を通して凹部２２内の加圧を継続するこ
とによってチップ抜き部材２１が押し下げられる。That is, the tip extracting member 21 is pushed down by continuing to pressurize the concave portion 22 through the air pipe 26 even after the expanding member 19 reaches the top dead center.
【００５２】尚、チップ抜き部材２１の外周面と筒部１
６との間に形成される隙間にはコイルバネ２７（その上
端部がチップ抜き部材２１の上端部に形成されたフラン
ジ部２８の下面に当接され、また、下端部が筒部１６の
内側に形成された段差面１６ａに当接されている。）が
介挿されており、チップ抜き部材２１の下降はこのコイ
ルバネ２７による上方への付勢力に抗して行われる。The outer peripheral surface of the chip removing member 21 and the cylindrical portion 1
The coil spring 27 (the upper end of which is in contact with the lower surface of the flange 28 formed at the upper end of the tip removing member 21 and the lower end of which is located inside the tubular portion 16) The stepped surface 16a is abutted against the stepped surface 16a, and the tip removing member 21 is lowered against the upward biasing force of the coil spring 27.
【００５３】よって、凹部２２内の圧力を下げればコイ
ルバネ２７の弾性力によってチップ抜き部材２１が上方
に押し戻されることになる。Therefore, if the pressure in the concave portion 22 is lowered, the elastic force of the coil spring 27 pushes the tip removing member 21 upward.
【００５４】尚、筒部１６の長孔１６ｂはチップ抜き部
材２１の移動に伴うエアー管２６の移動に支障を来さな
いように形成されたものである。The elongated hole 16b of the tubular portion 16 is formed so as not to hinder the movement of the air pipe 26 due to the movement of the tip removing member 21.
【００５５】図３乃至図５はチップ部１８の取り付けに
ついて時間の経過を追って順次説明するためのものであ
る。FIGS. 3 to 5 are for sequentially explaining the attachment of the tip portion 18 with the passage of time.
【００５６】図３はチップ部１８をチップシャフト１７
に挿合した状態を示すものである。In FIG. 3, the tip portion 18 is replaced by the tip shaft 17
It shows a state of being inserted into.
【００５７】即ち、チップ部１８の上端部１８ａがチッ
プシャフト１７の被挿合部１７ｂに挿合されており、拡
径部材１９やチップ抜き部材２１はそれらに許される移
動範囲において最も高い位置にある。That is, the upper end portion 18a of the tip portion 18 is inserted into the inserted portion 17b of the tip shaft 17, and the diameter-expanding member 19 and the tip extracting member 21 are at the highest position in the movement range allowed for them. is there.
【００５８】尚、Ｏリング２０はチップ部１８の上端部
１８ａの内壁に軽く当接した状態となっているが、チッ
プ部１８を被挿合部１７ｂに挿合する際にＯリング２０
が抵抗とならない寸法関係が成立している。Although the O-ring 20 is in a state of abutting lightly on the inner wall of the upper end portion 18a of the tip portion 18, the O-ring 20 is inserted when the tip portion 18 is fitted into the fitted portion 17b.
A dimensional relationship that does not become a resistance is established.
【００５９】次に、エアー管２４を通して凹部１５内を
加圧すると拡径部材１９が下降し、図４に示すように、
Ｏリング２０はその内径が拡径部材１９のテーパー部１
９ｂによって押し拡げられるため、Ｏリング２０がテー
パー部１９ｂとチップ部１８の上端部１８ａの内壁との
間で押し潰された状態になる。Next, when the inside of the concave portion 15 is pressurized through the air pipe 24, the diameter expansion member 19 descends, and as shown in FIG.
The O-ring 20 has an inner diameter that is the taper portion 1 of the expanding member 19.
Since it is pushed and spread by 9b, the O-ring 20 is crushed between the tapered portion 19b and the inner wall of the upper end portion 18a of the tip portion 18.
【００６０】図５は拡径部材１９がさらに下降してその
下端部１９ｃがチップシャフト１７の凹部１７ｃの内底
面に突き当たった状態を示しており、Ｏリング２０は拡
径部材１９のテーパー部１９ｂを乗り越えて該テーパー
部１９ｂの稍上部とチップ部１８の上端部１８ａの内壁
との間で最も潰された状態になる。FIG. 5 shows a state in which the diameter-expanding member 19 is further lowered and its lower end portion 19c abuts against the inner bottom surface of the recess 17c of the tip shaft 17, and the O-ring 20 is the taper portion 19b of the diameter-expanding member 19. After passing through, the most crushed state is formed between the upper part of the tapered part 19b and the inner wall of the upper end part 18a of the tip part 18.
【００６１】これによってチップ部１８とチップシャフ
ト１７の被挿合部１７ｂとの間のシールが確実になされ
るので、その後液体を採取するためにチップ部１８内を
減圧したり、液体を排出するためにチップ部１８内を加
圧した時にチップ部１８とチップシャフト１７の被挿合
部１７ｂとの間の隙間を通してエアーが出入りするのを
防止することができる。As a result, the tip portion 18 and the inserted portion 17b of the tip shaft 17 are securely sealed, so that the inside of the tip portion 18 is depressurized or the liquid is discharged to collect the liquid thereafter. Therefore, when pressure is applied to the inside of the tip portion 18, it is possible to prevent air from entering and exiting through the gap between the tip portion 18 and the inserted portion 17b of the tip shaft 17.
【００６２】つまり、液体の採取量や排出量は圧力制御
によって管理されるため、エアー漏れ等による圧力変動
の影響を抑えることで精度の良い計量を行うことができ
る。That is, since the amount of collected liquid and the amount of discharged liquid are managed by pressure control, accurate measurement can be performed by suppressing the influence of pressure fluctuation due to air leakage or the like.
【００６３】次に、チップ部１８の取り外しについて説
明する。Next, the removal of the tip portion 18 will be described.
【００６４】エアー管２６を通してチップ抜き部材２１
の凹部２２内を加圧すると拡径部材１９が上昇し、上記
の説明とは逆に図５、図４、図３の順に従って状態が変
化する。The chip removing member 21 is passed through the air pipe 26.
When the inside of the concave portion 22 is pressurized, the diameter expansion member 19 rises, and the state changes in the order of FIGS. 5, 4, and 3, contrary to the above description.
【００６５】拡径部材１９が上死点に達した後も引き続
き凹部２２内を加圧すると、図６に示すようにチップ抜
き部材２１がコイルバネ２７の力に抗して下降し、その
下端面２１ａがチップ部１８を下方に突き出す。When the inside of the concave portion 22 is continuously pressed after the expanding member 19 reaches the top dead center, the tip removing member 21 descends against the force of the coil spring 27 as shown in FIG. 21a projects the tip portion 18 downward.
【００６６】拡径部材１９によるＯリング２０の変形は
解除されており、チップ部１８はチップシャフト１７の
被挿合部１７ｂに軽く挿合された状態となっているの
で、チップ抜き部材２１の下降によりチップ部１８を容
易に取り外すことができる。The O-ring 20 is not deformed by the diameter expanding member 19 and the tip portion 18 is lightly inserted into the inserted portion 17b of the tip shaft 17. The tip portion 18 can be easily removed by lowering.
【００６７】その後、エアー管２６を通してチップ抜き
部材２１の凹部２２内を減圧すると、コイルバネ２７の
弾性力によってチップ抜き部材２１が上昇し最終的に最
も高い位置に戻る。After that, when the pressure inside the concave portion 22 of the tip removing member 21 is reduced through the air pipe 26, the tip extracting member 21 is raised by the elastic force of the coil spring 27 and finally returns to the highest position.
【００６８】以上のようにピペット装置１Ａによれば、
チップ部１８を交換する際にチップ部１８に力をかけす
ぎることがなく、簡単に行うことができるので作業の自
動化に適しており、複数のチップ部１８が整列されたホ
ルダーの上方にピペット装置１Ａを一時的に待避した
後、ホルダーに配列されたチップ部１８のうちから所望
のものを選択して上記したチップ部１８の取り外しや取
り付けの操作を行えばチップ部の交換作業の能率化を図
ることができる。As described above, according to the pipette device 1A,
When exchanging the tip portion 18, it is suitable for automating the work because it can be easily performed without exerting too much force on the tip portion 18, and the pipette device is provided above the holder in which the plurality of tip portions 18 are aligned. After temporarily retracting 1A, if a desired one is selected from among the chip parts 18 arranged in the holder and the above-mentioned operation for removing and installing the chip part 18 is performed, the efficiency of the replacement work of the chip part is improved. Can be planned.
【００６９】[0069]
【発明の効果】以上に記載したところから明らかなよう
に、本発明ピペット装置によれば、チップ部と該チップ
部に挿合される被挿合部との間に生じる隙間をシールす
るためのシール部材と、該シール部材を変形させる拡径
手段とを設け、チップ部を被挿合部に軽く挿合しておい
てから、シール部材を拡径手段によって変形させること
でこれをチップ部に圧接させてチップ部と被挿合部との
間のシールを図るとともにチップ部を保持することがで
きる。As is apparent from the above description, according to the pipette device of the present invention, the gap formed between the tip portion and the fitted portion to be fitted in the tip portion is sealed. A seal member and a diameter-expanding means for deforming the seal member are provided, and the tip portion is lightly inserted into the insertion target portion, and then the seal member is deformed by the diameter-expanding means to form the tip portion on the tip portion. The tip portion can be held while the tip portion and the mating portion are sealed by pressing.
【００７０】よって、チップ部に無理な力をかけること
なくチップ部を被挿合部に取り付けることができ、チッ
プ部の交換作業を簡単にし、しかも、このためにチップ
部と被挿合部との間のシール性が悪化することはない。Therefore, the tip portion can be attached to the mating portion without applying an excessive force to the tip portion, which simplifies the replacement work of the tip portion, and for this reason, the tip portion and the mating portion are The sealing property between the two does not deteriorate.
【００７１】尚、上記実施例において示した具体的な形
状乃至構造は何れも本発明の具体化に当たってのほんの
一例を示したものにすぎず、これらによって本発明の技
術的範囲が限定的に解釈されるものではない。It should be noted that the specific shapes and structures shown in the above embodiments are merely examples for embodying the present invention, and the technical scope of the present invention is limitedly interpreted by these. It is not something that will be done.
【図１】本発明ピペット装置の原理的な説明図である。FIG. 1 is a principle explanatory view of a pipette device of the present invention.
【図２】ピペット装置の要部を示す断面図である。FIG. 2 is a sectional view showing a main part of a pipette device.
【図３】チップ部の取り付けについて説明するための拡
大断面図であり、拡径部材の下降前の状態を示す。FIG. 3 is an enlarged cross-sectional view for explaining the attachment of the tip portion, showing a state before the diameter-expanding member is lowered.
【図４】チップ部の取り付けについて説明するための拡
大断面図であり、拡径部材の下降途中の状態を示す。FIG. 4 is an enlarged cross-sectional view for explaining attachment of the tip portion, showing a state in which the diameter-expanding member is in the process of descending.
【図５】チップ部の取り付けについて説明するための拡
大断面図であり、拡径部材の下降終了時の状態を示す。FIG. 5 is an enlarged cross-sectional view for explaining attachment of the tip portion, showing a state at the end of lowering of the diameter expanding member.
【図６】チップ部の取り外しについて説明するための拡
大断面図である。FIG. 6 is an enlarged cross-sectional view for explaining removal of the tip portion.
１ ピペット装置 ２ａ 被挿合部 ３ チップ部 ８ シール部材 ９ 拡径手段 １１ 液体 １Ａ ピペット装置 １７ｂ 被挿合部 １８ チップ部 １９ 拡径手段（拡径部材） １９ｂ テーパー部 ２０ Ｏリング ２１ チップ抜き手段（チップ抜き部材） ２３ 空圧制御手段（エアーシリンダ） DESCRIPTION OF SYMBOLS 1 Pipette device 2a Inserted part 3 Tip part 8 Sealing member 9 Diameter expansion means 11 Liquid 1A Pipette device 17b Inserted part 18 Tip part 19 Diameter expansion means (diameter expansion member) 19b Tapered part 20 O-ring 21 Tip removal means (Tip removing member) 23 Pneumatic control means (air cylinder)
───────────────────────────────────────────────────── フロントページの続き (72)発明者 中町 啓一 東京都品川区北品川６丁目７番35号 ソニ ー株式会社内 ─────────────────────────────────────────────────── ─── Continuation of front page (72) Keiichi Nakamachi 6-7-35 Kita-Shinagawa, Shinagawa-ku, Tokyo Sony Corporation
Claims (4)
又は排出を行うようにしたピペット装置において、チッ
プ部と該チップ部が挿合される被挿合部との間に生じる
隙間をシールするためにシール部材を設け、該シール部
材を拡径手段によって変形させることによってシール部
材とチップ部との密着度を高めるようにしたことを特徴
とするピペット装置。1. In a pipette device adapted to collect or discharge a liquid by controlling the pressure in the tip part, for sealing a gap generated between the tip part and a fitting part into which the tip part is fitted. A pipette device, characterized in that a seal member is provided on the seal member, and the seal member is deformed by a diameter-expanding means to enhance the degree of adhesion between the seal member and the tip portion.
て、シール部材がＯリングとされるとともに、拡径手段
がテーパー部を有する移動可能な部材とされ、拡径手段
の移動に伴ってそのテーパー部がＯリングの径を拡げる
ことによりシール部材とチップ部との密着度を高めるよ
うにしたことを特徴とするピペット装置。2. The pipette device according to claim 1, wherein the seal member is an O-ring, and the diameter-expanding means is a movable member having a taper portion, and the taper is associated with the movement of the diameter-expanding means. The pipette device is characterized in that the diameter of the O-ring is expanded so that the degree of adhesion between the seal member and the tip portion is increased.
装置において、チップ部を被挿合部から取り外すための
チップ抜き手段を設け、拡径手段によるシール部材の変
形を解いた後チップ抜き手段の一部をチップ部に突き当
ててチップ部を被挿合部から外すようにしたことを特徴
とするピペット装置。3. The pipette device according to claim 1 or 2, further comprising a tip removing means for removing the tip portion from the fitted portion, and after removing the deformation of the seal member by the diameter expanding means, the tip removing operation is performed. A pipette device, characterized in that a part of the means is abutted against the tip part to remove the tip part from the inserted part.
て、拡径手段とチップ抜き手段とを空気圧を利用して移
動制御する一の空圧制御手段を設け、チップ部を被挿合
部に挿合した後に空圧制御手段が拡径手段を移動させて
シール部材の変形によりシール部材とチップ部との密着
度を高め、また、チップ部を被挿合部から取り外す際に
は空圧制御手段が拡径手段を移動させてシール部材の変
形を解いてからチップ抜き手段を移動させてその一部を
チップ部に突き当ててチップ部を被挿合部から外すよう
にしたことを特徴とするピペット装置。4. The pipette device according to claim 3, wherein one pneumatic pressure control means for controlling the movement of the diameter expanding means and the tip removing means using air pressure is provided, and the tip portion is inserted into the insertion portion. After fitting, the air pressure control means moves the diameter expansion means to improve the degree of adhesion between the seal member and the tip portion by the deformation of the seal member, and when removing the tip portion from the mating portion, the air pressure control means Characterized in that the diameter expanding means is moved to release the deformation of the seal member, and then the tip removing means is moved so that a part thereof is abutted against the tip part to remove the tip part from the mating part. Pipette device.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13098793A JP3395250B2 (en) | 1993-05-10 | 1993-05-10 | Pipette equipment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13098793A JP3395250B2 (en) | 1993-05-10 | 1993-05-10 | Pipette equipment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH06320021A true JPH06320021A (en) | 1994-11-22 |
| JP3395250B2 JP3395250B2 (en) | 2003-04-07 |
Family
ID=15047274
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP13098793A Expired - Fee Related JP3395250B2 (en) | 1993-05-10 | 1993-05-10 | Pipette equipment |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP3395250B2 (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06323964A (en) * | 1993-05-13 | 1994-11-25 | Japan Energy Corp | Liquid sample dispenser |
| WO2000072971A1 (en) * | 1999-05-31 | 2000-12-07 | Bridgestone Corporation | Pipetter |
| US7033543B1 (en) | 1999-04-16 | 2006-04-25 | Hamilton Bonaduz Ag | Pipette tip, pipetting device and combination consisting of a pipette tip and pipetting device |
| WO2018002254A1 (en) * | 2016-06-29 | 2018-01-04 | Eppendorf Ag | Metering head, metering device comprising a metering head, and method for metering by means of a metering head |
| JP2019519366A (en) * | 2016-06-15 | 2019-07-11 | ハミルトン カンパニーＨａｍｉｌｔｏｎ Ｃｏｍｐａｎｙ | Pipette device, pipette tip coupler, and pipette tip, apparatus and method |
| JP2021508588A (en) * | 2017-11-10 | 2021-03-11 | ハミルトン・ボナドゥーツ・アーゲー | A pipette device with an electromagnetically driveable lock actuator to lock the unlockably coupled pipette tip |
-
1993
- 1993-05-10 JP JP13098793A patent/JP3395250B2/en not_active Expired - Fee Related
Cited By (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06323964A (en) * | 1993-05-13 | 1994-11-25 | Japan Energy Corp | Liquid sample dispenser |
| US7033543B1 (en) | 1999-04-16 | 2006-04-25 | Hamilton Bonaduz Ag | Pipette tip, pipetting device and combination consisting of a pipette tip and pipetting device |
| US9415388B2 (en) | 1999-04-16 | 2016-08-16 | Hamilton Bonaduz Ag | Pipette tip, pipette device, and combination of pipette tip and pipette device |
| WO2000072971A1 (en) * | 1999-05-31 | 2000-12-07 | Bridgestone Corporation | Pipetter |
| US6673318B1 (en) | 1999-05-31 | 2004-01-06 | Bridgestone Corporation | Pipette |
| JP2019215353A (en) * | 2016-06-15 | 2019-12-19 | ハミルトン カンパニーＨａｍｉｌｔｏｎ Ｃｏｍｐａｎｙ | Pipette device, pipette tip coupler and pipette tip, device, and method |
| JP2019193940A (en) * | 2016-06-15 | 2019-11-07 | ハミルトン カンパニーＨａｍｉｌｔｏｎ Ｃｏｍｐａｎｙ | Pipet device, pipette tip coupler, pipette tip, devices and methods |
| JP2019519366A (en) * | 2016-06-15 | 2019-07-11 | ハミルトン カンパニーＨａｍｉｌｔｏｎ Ｃｏｍｐａｎｙ | Pipette device, pipette tip coupler, and pipette tip, apparatus and method |
| JP2019184619A (en) * | 2016-06-15 | 2019-10-24 | ハミルトン カンパニーＨａｍｉｌｔｏｎ Ｃｏｍｐａｎｙ | Pipetting device, pipette tip coupler, pipette tip, device, and method |
| JP2019193939A (en) * | 2016-06-15 | 2019-11-07 | ハミルトン カンパニーＨａｍｉｌｔｏｎ Ｃｏｍｐａｎｙ | Pipet device, pipette tip coupler, pipette tip, devices and methods |
| JP2019193941A (en) * | 2016-06-15 | 2019-11-07 | ハミルトン カンパニーＨａｍｉｌｔｏｎ Ｃｏｍｐａｎｙ | Pipet device, pipette tip coupler, pipette tip, devices and methods |
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| JP2019214043A (en) * | 2016-06-15 | 2019-12-19 | ハミルトン カンパニーＨａｍｉｌｔｏｎ Ｃｏｍｐａｎｙ | Pipet device, pipette tip coupler, pipette tip, devices and methods |
| JP2019193937A (en) * | 2016-06-15 | 2019-11-07 | ハミルトン カンパニーＨａｍｉｌｔｏｎ Ｃｏｍｐａｎｙ | Pipet device, pipette tip coupler, pipette tip, devices and methods |
| CN109475872A (en) * | 2016-06-29 | 2019-03-15 | 埃佩多夫股份公司 | Metering head, the metering device including metering head and the method for being measured by metering head |
| WO2018002254A1 (en) * | 2016-06-29 | 2018-01-04 | Eppendorf Ag | Metering head, metering device comprising a metering head, and method for metering by means of a metering head |
| US11305292B2 (en) | 2016-06-29 | 2022-04-19 | Eppendorf Ag | Metering head, metering device comprising a metering head, and method for metering by means of a metering head |
| CN109475872B (en) * | 2016-06-29 | 2022-10-11 | 埃佩多夫股份公司 | Metering head, metering device comprising a metering head and method for metering by a metering head |
| US11980891B2 (en) | 2016-06-29 | 2024-05-14 | Eppendorf Group SE & Co. KG | Metering head, metering device comprising a metering head, and method for metering by means of a metering head |
| JP2021508588A (en) * | 2017-11-10 | 2021-03-11 | ハミルトン・ボナドゥーツ・アーゲー | A pipette device with an electromagnetically driveable lock actuator to lock the unlockably coupled pipette tip |
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| JP3395250B2 (en) | 2003-04-07 |
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