JPH0467011A - Production of contact lens - Google Patents
Production of contact lensInfo
- Publication number
- JPH0467011A JPH0467011A JP17845090A JP17845090A JPH0467011A JP H0467011 A JPH0467011 A JP H0467011A JP 17845090 A JP17845090 A JP 17845090A JP 17845090 A JP17845090 A JP 17845090A JP H0467011 A JPH0467011 A JP H0467011A
- Authority
- JP
- Japan
- Prior art keywords
- acrylamide
- graft
- base material
- lens base
- contact lens
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 7
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical group NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 claims abstract description 20
- 239000000463 material Substances 0.000 claims abstract description 19
- -1 alkyl methacrylate Chemical compound 0.000 claims abstract description 13
- 239000003431 cross linking reagent Substances 0.000 claims abstract description 11
- 229920001577 copolymer Polymers 0.000 claims abstract description 5
- 229920000642 polymer Polymers 0.000 claims abstract description 4
- 125000000217 alkyl group Chemical group 0.000 claims description 4
- 238000010559 graft polymerization reaction Methods 0.000 claims description 4
- 239000000126 substance Substances 0.000 claims 2
- 229920000578 graft copolymer Polymers 0.000 abstract description 8
- 208000028659 discharge Diseases 0.000 abstract description 6
- 238000011282 treatment Methods 0.000 abstract description 5
- ZIUHHBKFKCYYJD-UHFFFAOYSA-N n,n'-methylenebisacrylamide Chemical compound C=CC(=O)NCNC(=O)C=C ZIUHHBKFKCYYJD-UHFFFAOYSA-N 0.000 abstract description 4
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 abstract description 3
- 239000000178 monomer Substances 0.000 abstract description 3
- 239000000853 adhesive Substances 0.000 abstract 1
- 230000001070 adhesive effect Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 239000007864 aqueous solution Substances 0.000 description 5
- 238000005299 abrasion Methods 0.000 description 3
- 238000004132 cross linking Methods 0.000 description 3
- 238000006116 polymerization reaction Methods 0.000 description 3
- XFCMNSHQOZQILR-UHFFFAOYSA-N 2-[2-(2-methylprop-2-enoyloxy)ethoxy]ethyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCCOCCOC(=O)C(C)=C XFCMNSHQOZQILR-UHFFFAOYSA-N 0.000 description 2
- BESKSSIEODQWBP-UHFFFAOYSA-N 3-tris(trimethylsilyloxy)silylpropyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C BESKSSIEODQWBP-UHFFFAOYSA-N 0.000 description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical group N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- VVQNEPGJFQJSBK-UHFFFAOYSA-N Methyl methacrylate Chemical compound COC(=O)C(C)=C VVQNEPGJFQJSBK-UHFFFAOYSA-N 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 238000007796 conventional method Methods 0.000 description 2
- 239000003599 detergent Substances 0.000 description 2
- 229910001873 dinitrogen Inorganic materials 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- VDYWHVQKENANGY-UHFFFAOYSA-N 1,3-Butyleneglycol dimethacrylate Chemical compound CC(=C)C(=O)OC(C)CCOC(=O)C(C)=C VDYWHVQKENANGY-UHFFFAOYSA-N 0.000 description 1
- HWSSEYVMGDIFMH-UHFFFAOYSA-N 2-[2-[2-(2-methylprop-2-enoyloxy)ethoxy]ethoxy]ethyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCCOCCOCCOC(=O)C(C)=C HWSSEYVMGDIFMH-UHFFFAOYSA-N 0.000 description 1
- 125000000954 2-hydroxyethyl group Chemical group [H]C([*])([H])C([H])([H])O[H] 0.000 description 1
- DBCAQXHNJOFNGC-UHFFFAOYSA-N 4-bromo-1,1,1-trifluorobutane Chemical compound FC(F)(F)CCCBr DBCAQXHNJOFNGC-UHFFFAOYSA-N 0.000 description 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 description 1
- 239000011837 N,N-methylenebisacrylamide Substances 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- 229920001328 Polyvinylidene chloride Polymers 0.000 description 1
- DAKWPKUUDNSNPN-UHFFFAOYSA-N Trimethylolpropane triacrylate Chemical compound C=CC(=O)OCC(CC)(COC(=O)C=C)COC(=O)C=C DAKWPKUUDNSNPN-UHFFFAOYSA-N 0.000 description 1
- 150000001252 acrylic acid derivatives Chemical class 0.000 description 1
- 239000012300 argon atmosphere Substances 0.000 description 1
- 210000004087 cornea Anatomy 0.000 description 1
- 238000003851 corona treatment Methods 0.000 description 1
- STVZJERGLQHEKB-UHFFFAOYSA-N ethylene glycol dimethacrylate Substances CC(=C)C(=O)OCCOC(=O)C(C)=C STVZJERGLQHEKB-UHFFFAOYSA-N 0.000 description 1
- 239000010408 film Substances 0.000 description 1
- 229940127554 medical product Drugs 0.000 description 1
- 150000002734 metacrylic acid derivatives Chemical class 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 239000005022 packaging material Substances 0.000 description 1
- 239000002985 plastic film Substances 0.000 description 1
- 229920006255 plastic film Polymers 0.000 description 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
- 229920002401 polyacrylamide Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 230000000379 polymerizing effect Effects 0.000 description 1
- 239000004926 polymethyl methacrylate Substances 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- 239000004800 polyvinyl chloride Substances 0.000 description 1
- 239000005033 polyvinylidene chloride Substances 0.000 description 1
- FAIDIRVMPHBRLT-UHFFFAOYSA-N propane-1,2,3-triol;prop-2-enoic acid Chemical compound OC(=O)C=C.OC(=O)C=C.OCC(O)CO FAIDIRVMPHBRLT-UHFFFAOYSA-N 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 125000006850 spacer group Chemical group 0.000 description 1
- 238000004381 surface treatment Methods 0.000 description 1
Landscapes
- Eyeglasses (AREA)
- Surface Treatment Of Optical Elements (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Macromonomer-Based Addition Polymer (AREA)
Abstract
Description
【発明の詳細な説明】
Ｃ産業上の利用分野コ
本発明はコンタクトレンズに関し特に濡れ性と装用感に
優れるハードコンタクトレンズに関する。DETAILED DESCRIPTION OF THE INVENTION Field of the Invention The present invention relates to contact lenses, and particularly to hard contact lenses that are excellent in wettability and wear comfort.
［従来の技術］
コンタクトレンズ装用時の異物感を減少させて装用感を
向上させるには、角膜とレンズ表面とのなじみを良くす
ることが重要である。具体的な方法としては、コンタク
トレンズ表面に親水性モノマーであるアクリルアミドを
グラフト重合することにより、レンズ表面の濡れ性を向
上させることがあげられる。従来、アクリルアミドモノ
マーのみをコンタクトレンズ基材と接触させてグラフト
重合を行なっていた。[Prior Art] In order to reduce the feeling of a foreign body when wearing a contact lens and improve the feeling of wearing it, it is important to improve the compatibility between the cornea and the lens surface. A specific method is to improve the wettability of the lens surface by graft polymerizing acrylamide, which is a hydrophilic monomer, onto the surface of the contact lens. Conventionally, graft polymerization has been carried out by bringing only acrylamide monomer into contact with a contact lens base material.
［発明が解決しようとする課Ｍ］
しかし、前述の従来技術では、グラフトポリマーとレン
ズ基材との密着強度が小さく、指などでこするとグラフ
トポリマーがはげ落ちてしまい、グラフト前の濡れ性に
戻ってしまうという欠点を有していた。そこで本発明は
この問題点を解決するもので、その目的とするところは
、レンズ基材とグラフトポリマーとの密着強度を向上さ
せた、耐摩耗性の高いコンタクトレンズの製造方法を提
供することにある。[Problem M to be solved by the invention] However, in the above-mentioned conventional technology, the adhesion strength between the graft polymer and the lens base material is low, and the graft polymer peels off when rubbed with fingers, resulting in poor wettability before grafting. It had the disadvantage of returning. Therefore, the present invention is intended to solve this problem, and its purpose is to provide a method for manufacturing contact lenses with high wear resistance that improves the adhesion strength between the lens base material and the graft polymer. be.
［課題を解決するための手段］
上記課題を解決するために本発明のコンタクトレンズの
製造方法は、 （ａ）少なくとも、アルキルメタクリレ
ートとシロキサニルメタクリレート式中ＸおよびＹはＣ
１〜Ｃ５のアルキル基およびＺ基からなる群から選ばれ
、Ｚは構造式
をもつ基であり、Ａは０１〜Ｃ５のアルキル基を示す。[Means for Solving the Problems] In order to solve the above problems, the method for manufacturing a contact lens of the present invention includes: (a) at least alkyl methacrylate and siloxanyl methacrylate in which X and Y are C;
selected from the group consisting of a 1-C5 alkyl group and a Z group, Z is a group having a structural formula, and A represents an 01-C5 alkyl group.
ｍ、 ｎは０．又は正の整数を示す。）との共重合物
であるメタクリル酸のエステル化合物のポリマーを原材
料としたコンタクトレンズ基材において、その表面を常
圧あるいは減圧下で放電処理する工程と、 （ｂ）レン
ズ表面にアクリルアミドをグラフト重合する工程とから
成るコンタクトレンズの製造方法において、 （ｂ）工
程中のアクリルアミドモノマー水溶液に架橋剤を添加す
ることを特徴とする。m and n are 0. Or indicates a positive integer. (b) Graft polymerization of acrylamide onto the lens surface in a contact lens base material made from a polymer of an ester compound of methacrylic acid, which is a copolymer with A method for manufacturing a contact lens comprising the steps of (b) adding a crosslinking agent to the aqueous acrylamide monomer solution in step (b).
なお、代表的なメタクリル酸のエステル化合物には以下
のものがあげられる。In addition, the following are listed as typical ester compounds of methacrylic acid.
ペンタメチルジシロキサニルメチルメタクリレート
イソブチルヘキサメチルトリシロキサニルメチルメタク
リレート
トリス（トリメチルシロキシ）−γ−メタクリルオキシ
プロピルシラン
ＣＨ３
者
ＣＨ３−８ｉ−ＣＨ３
ＣＨ３−８ｉ−ＣＨ３
ＣＨ３
以下、実施例により本発明の詳細を示す。Pentamethyldisiloxanyl methyl methacrylate Isobutyl hexamethyltrisiloxanyl methyl methacrylate Tris(trimethylsiloxy)-γ-methacryloxypropylsilane Show details.
［実施例１］
架橋剤であるＮ、Ｎ’−メチレンビスアクリルアミド２
．５ｇ、アクリルアミド１０ｇを水に溶かして１００ｍ
１とし、モノマー水溶液を調製した。[Example 1] Crosslinking agent N,N'-methylenebisacrylamide 2
．． Dissolve 5g and 10g of acrylamide in water for 100m
1, and an aqueous monomer solution was prepared.
グラフト重合は次のようにして行なった。メチルメタク
リレート６０ｗｔ％、トリス（トリメチルシロキシ）シ
リルプロピルメタクリレート３５ｗｔ％、２−ヒドロキ
シエチルメタクリレート５ｗｔ％の共重合物よりなるコ
ンタクトレンズ基材を用意した。放電装置（電極間６セ
ンチメードル、電極間電圧２７０ボルト、周波数６０ヘ
ルツ）にレンズ基材を設置して、０．０４１−−ルのア
ルゴン雰囲気中で５秒間グロー放電処理をした。放電処
理したレンズ基材を空気中にさらした後、試験管に入れ
、架橋剤添加アクリルアミドモノマー水溶液を加え窒素
ガス置換後、減圧封管した。試験管を８０°Ｃの恒温槽
中に６０分置き、レンズ基材表面にアクリルアミドをグ
ラフト重合した（試料Ｎ０１１〜６）。また、従来法と
の比較のため、架橋剤未添加の１０ｗｔ％アクリルアミ
ドモノマー水溶液を用いた試料を作製した。 （比較例
１〜６）この時の重合条件は、架橋剤添加の試料と全く
同様な操作を施した。併せて、処理後のレンズを、洗剤
をまぶした掌で１０００往復こすり洗いをし、耐摩耗性
試験を行なった。グラフトポリマーの剥離評価は、こす
り前とこすり後のレンズ表面の接触角の変化で検討した
。接触角の測定は液適法にて行い、溶媒は水を使用した
。これらの結果を第１表に掲げる。Graft polymerization was carried out as follows. A contact lens base material made of a copolymer of 60 wt% methyl methacrylate, 35 wt% tris(trimethylsiloxy)silylpropyl methacrylate, and 5 wt% 2-hydroxyethyl methacrylate was prepared. The lens base material was placed in a discharge device (electrode spacing 6 cm, interelectrode voltage 270 volts, frequency 60 hertz), and glow discharge treatment was performed for 5 seconds in an argon atmosphere of 0.041 mm. After exposing the discharge-treated lens base material to the air, it was placed in a test tube, a crosslinking agent-added acrylamide monomer aqueous solution was added, the tube was replaced with nitrogen gas, and the tube was sealed under reduced pressure. The test tube was placed in a constant temperature bath at 80° C. for 60 minutes, and acrylamide was graft-polymerized on the surface of the lens base material (Samples Nos. 011 to 6). In addition, for comparison with the conventional method, a sample was prepared using a 10 wt % acrylamide monomer aqueous solution to which no crosslinking agent was added. (Comparative Examples 1 to 6) The polymerization conditions at this time were exactly the same as those for the samples with the addition of a crosslinking agent. In addition, the treated lenses were rubbed 1,000 times with the palm of the hand sprinkled with detergent to perform an abrasion resistance test. Graft polymer peeling was evaluated by examining the change in contact angle between the lens surface before and after rubbing. The contact angle was measured by the dripping method, and water was used as the solvent. These results are listed in Table 1.
第１表
メチルメタクリレート６０ｗｔ％、トリス（トリメチル
シロキシ）シリルプロピルメタクリレート３５ｗｔ％、
２−ヒドロキシエチルメタクワレート５ｗｔ％の共重合
物よりなるコンタクトレンズ基材を用意した。電極間路
９３． ５センチメートル、電極間電圧１５キロボルト
、周波数６０ヘルツのコロナ放電処理装置の電極間に厚
み１．５ミリメートルのスペーサで作った空間にこのレ
ンズ基材を設置し、放電処理をおこなった。尚、片面ず
つ、両面に４０秒ずつ放電処理をした。次にこの放電処
理したレンズ基材を試験管に入れ、そこへ実施例１に用
いたものと同様の架橋剤添加アクリルアミドモノマー水
溶液を加え窒素ガス置換後、減圧封管した。試験管を８
０°Ｃの恒温槽中に６０分置き、レンズ基材表面にアク
リルアミドをグラフト重合した（試料ＮＯ，１〜６）。Table 1 Methyl methacrylate 60 wt%, tris(trimethylsiloxy)silylpropyl methacrylate 35 wt%,
A contact lens base material made of a copolymer of 5 wt% 2-hydroxyethyl methacryate was prepared. Interelectrode path 93. This lens base material was placed in a space created by a 1.5 mm thick spacer between the electrodes of a corona discharge treatment device with a diameter of 5 cm, an interelectrode voltage of 15 kilovolts, and a frequency of 60 Hz, and discharge treatment was performed. Incidentally, discharge treatment was applied to one side and both sides for 40 seconds each. Next, this discharge-treated lens base material was placed in a test tube, and the same crosslinking agent-added acrylamide monomer aqueous solution as used in Example 1 was added thereto, and the tube was sealed under reduced pressure after purging with nitrogen gas. 8 test tubes
The lenses were placed in a constant temperature bath at 0° C. for 60 minutes to graft-polymerize acrylamide onto the surface of the lens base material (Samples Nos. 1 to 6).
また、従来法との比較のため、架橋剤未添加の１０ｗｔ
％アクリルアミド水溶液を用いた試料を作製した。In addition, for comparison with the conventional method, 10 wt without crosslinking agent was added.
% acrylamide aqueous solution was prepared.
（比較例１〜６）この時の重合条件は架橋剤添加の試料
と全く同様な操作を施した。併せて、処理後のレンズを
、洗剤をまぶした掌で１０００往復こすり洗いをし、耐
摩耗性試験を行なった。グラフトポリマーの剥離評価は
、こすり前とこすり後のレンズ表面の接触角の変化で検
討した。接触角の測定は液適法にて行い、溶媒は水を使
用した。(Comparative Examples 1 to 6) The polymerization conditions at this time were exactly the same as those for the samples in which a crosslinking agent was added. In addition, the treated lenses were rubbed 1,000 times with the palm of the hand sprinkled with detergent to perform an abrasion resistance test. Graft polymer peeling was evaluated by examining the change in contact angle between the lens surface before and after rubbing. The contact angle was measured by the dripping method, and water was used as the solvent.
これらの結果を第２表に掲げる。These results are listed in Table 2.
第２表
第１ｆｉＥよひ第２坂より明かなように、こすり後の接
触角の上昇は、架橋剤を添加することにより大幅に抑制
され、レンズ表面の水濡れ性は保持された。すなわち、
アクリルアミドポリマーはＮ、Ｎ−メチレンビスアクリ
ルアミド架橋することにより、レンズ基材とグラフトポ
リマーの密着強度が大きくなり、グラフトレンズ表面の
耐摩耗性を向上させることができた。As is clear from the second slope of Table 2, the increase in the contact angle after rubbing was significantly suppressed by adding the crosslinking agent, and the water wettability of the lens surface was maintained. That is,
By crosslinking the acrylamide polymer with N,N-methylenebisacrylamide, the adhesion strength between the lens base material and the graft polymer was increased, and the abrasion resistance of the graft lens surface was able to be improved.
本発明の実施例をＳｉ系ＰＭＭＡ製コンタクトレンズと
を用いて説明してきたが、これに限られることなくポリ
エチレンフィルム、ポリプロピレン、ポリ塩化ビニル、
ポリ塩化ビニリデン、アセテート、ポリエステル、ポリ
ビニルアルコール、ポリスチレン、ポリカーボネート、
その他種々なプラスチックフィルムの表面処理に対して
も同様な結果が得られた。更に、上にあげた樹朋を使用
した各種包装材、農業用保水材、または人工臓器などの
医療用製品にも応用が可能である。Although the embodiments of the present invention have been explained using Si-based PMMA contact lenses, the present invention is not limited thereto, and is not limited to polyethylene films, polypropylene, polyvinyl chloride,
Polyvinylidene chloride, acetate, polyester, polyvinyl alcohol, polystyrene, polycarbonate,
Similar results were obtained for surface treatments of various other plastic films. Furthermore, the above-mentioned trees can be used in various packaging materials, agricultural water retaining materials, and medical products such as artificial organs.
また、架橋剤としてグリセリンジアクリレート、トリメ
チロールプロパントリアクリレートなどのアクリレート
系、およびエチレングリコールジメタクリレート、ジエ
チレングイコールジメタクリレート、 トリエチレング
リコールジメタクリレート、１．３−ブタンジオールジ
メタクリレートなどのメタクリレート系を用いても同様
な結果が得られた。In addition, as a crosslinking agent, acrylates such as glycerin diacrylate and trimethylolpropane triacrylate, and methacrylates such as ethylene glycol dimethacrylate, diethylene glycol dimethacrylate, triethylene glycol dimethacrylate, and 1,3-butanediol dimethacrylate are used. Similar results were obtained using
［発明の効果コ
以上述べたように、発明によれば、重合系たるアクリル
アミドモノマー水溶液にＮ、Ｎ’−メチレンビスアクリ
ルアミドを添加することにより、グラフト処理したポリ
マーは架橋構造をとり、レンズ基材との密着強度が強ま
って耐摩耗性が飛躍的に向上した。これは、コンタクト
レンズの水濡れ性を長期にわたって保持できるという効
果を有する。[Effects of the Invention] As described above, according to the invention, by adding N,N'-methylenebisacrylamide to the acrylamide monomer aqueous solution that is the polymerization system, the grafted polymer takes on a crosslinked structure and forms a lens base material. The adhesion strength has been strengthened and wear resistance has been dramatically improved. This has the effect that the water wettability of the contact lens can be maintained for a long period of time.
従って、本発明は装用感に優れるコンタクトレンズの製
造に関し、たいへん有効な方法であるといえる。Therefore, the present invention can be said to be a very effective method for producing contact lenses that are comfortable to wear.
以 上 出願人 セイコーエプソン株式会社that's all Applicant: Seiko Epson Corporation
Claims (1)
ニルメタクリレート（ ▲数式、化学式、表等があります▼ 式中ＸおよびＹはＣ＿１〜Ｃ＿５のアルキル基およびＺ
基からなる群から選ばれ、Ｚは構造式 ▲数式、化学式、表等があります▼ をもつ基であり、ＡはＣ＿１〜Ｃ＿５のアルキル基を示
す。ｍ、ｎは０、又は正の整数を示す。）との共重合物
であるメタクリル酸のエステル化合物のポリマーを原材
料としたコンタクトレンズ基材において、その表面を常
圧あるいは減圧下で放電処理する工程と、（ｂ）レンズ
表面にアクリルアミドをグラフト重合する工程とから成
るコンタクトレンズの製造方法において、（ｂ）工程中
のアクリルアミドモノマー水溶液に架橋剤を添加するこ
とを特徴とするコンタクトレンズの製造方法。[Claims] (a) At least alkyl methacrylate and siloxanyl methacrylate (▲There are mathematical formulas, chemical formulas, tables, etc.▼ In the formula, X and Y are C_1 to C_5 alkyl groups and Z
is selected from the group consisting of groups, Z is a group having the structural formula ▲ Numerical formula, chemical formula, table, etc. ▼, and A represents an alkyl group of C_1 to C_5. m and n represent 0 or a positive integer. (b) Graft polymerization of acrylamide onto the lens surface in a contact lens base material made from a polymer of a methacrylic acid ester compound, which is a copolymer with A method for producing a contact lens comprising the step of (b) adding a crosslinking agent to the aqueous acrylamide monomer solution in step (b).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP17845090A JPH0467011A (en) | 1990-07-05 | 1990-07-05 | Production of contact lens |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP17845090A JPH0467011A (en) | 1990-07-05 | 1990-07-05 | Production of contact lens |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH0467011A true JPH0467011A (en) | 1992-03-03 |
Family
ID=16048734
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP17845090A Pending JPH0467011A (en) | 1990-07-05 | 1990-07-05 | Production of contact lens |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH0467011A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5391589A (en) * | 1991-12-10 | 1995-02-21 | Seiko Epson Corporation | Contact lens and method of producing a contact lens |
-
1990
- 1990-07-05 JP JP17845090A patent/JPH0467011A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5391589A (en) * | 1991-12-10 | 1995-02-21 | Seiko Epson Corporation | Contact lens and method of producing a contact lens |
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