JPH046443A - Flow cell device and manufacture thereof - Google Patents
Flow cell device and manufacture thereofInfo
- Publication number
- JPH046443A JPH046443A JP10759390A JP10759390A JPH046443A JP H046443 A JPH046443 A JP H046443A JP 10759390 A JP10759390 A JP 10759390A JP 10759390 A JP10759390 A JP 10759390A JP H046443 A JPH046443 A JP H046443A
- Authority
- JP
- Japan
- Prior art keywords
- plated
- corrosion resistance
- plating
- flow cell
- cell device
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000004519 manufacturing process Methods 0.000 title description 5
- 238000007747 plating Methods 0.000 claims abstract description 19
- 229910018104 Ni-P Inorganic materials 0.000 claims abstract description 13
- 229910018536 Ni—P Inorganic materials 0.000 claims abstract description 13
- 238000005219 brazing Methods 0.000 claims abstract description 11
- 238000010030 laminating Methods 0.000 claims abstract description 5
- 238000002844 melting Methods 0.000 claims abstract description 5
- 230000008018 melting Effects 0.000 claims abstract description 5
- 239000000956 alloy Substances 0.000 claims abstract description 3
- 229910045601 alloy Inorganic materials 0.000 claims abstract description 3
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 6
- 229910052742 iron Inorganic materials 0.000 claims description 3
- 230000007797 corrosion Effects 0.000 abstract description 14
- 238000005260 corrosion Methods 0.000 abstract description 14
- 230000003746 surface roughness Effects 0.000 abstract description 7
- 239000000463 material Substances 0.000 abstract description 5
- 239000002184 metal Substances 0.000 abstract description 5
- 229910052751 metal Inorganic materials 0.000 abstract description 5
- 239000000203 mixture Substances 0.000 abstract description 2
- 238000007772 electroless plating Methods 0.000 abstract 1
- 239000000945 filler Substances 0.000 abstract 1
- 239000011521 glass Substances 0.000 description 4
- 229920001721 polyimide Polymers 0.000 description 4
- 230000000694 effects Effects 0.000 description 2
- 229910000833 kovar Inorganic materials 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 239000004642 Polyimide Substances 0.000 description 1
- DPKHZNPWBDQZCN-UHFFFAOYSA-N acridine orange free base Chemical compound C1=CC(N(C)C)=CC2=NC3=CC(N(C)C)=CC=C3C=C21 DPKHZNPWBDQZCN-UHFFFAOYSA-N 0.000 description 1
- DZBUGLKDJFMEHC-UHFFFAOYSA-N benzoquinolinylidene Natural products C1=CC=CC2=CC3=CC=CC=C3N=C21 DZBUGLKDJFMEHC-UHFFFAOYSA-N 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 238000005304 joining Methods 0.000 description 1
- 210000003127 knee Anatomy 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 229920003002 synthetic resin Polymers 0.000 description 1
- 239000000057 synthetic resin Substances 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
Landscapes
- Investigating Or Analysing Biological Materials (AREA)
- Optical Measuring Cells (AREA)
Abstract
Description
【発明の詳細な説明】
〔産業上の利用分野〕
本発明は臨床用細胞分析装置におけるフローセル装置で
、信頼性、耐食性、量産性にすぐれたフローセル装置及
びその製法に関する。DETAILED DESCRIPTION OF THE INVENTION [Field of Industrial Application] The present invention relates to a flow cell device for a clinical cell analyzer, and relates to a flow cell device with excellent reliability, corrosion resistance, and mass productivity, and a manufacturing method thereof.
従来の装置は、特開平１−２６１２５号公報に記載のよ
うに、複数のガラス板とポリイミドのような合成樹脂板
を交互に積層後接着して製法していた。Conventional apparatuses have been manufactured by alternately laminating and bonding a plurality of glass plates and synthetic resin plates such as polyimide, as described in JP-A-1-26125.
上記従来技術のフローセル装置では、ガラス板とポリイ
ミドフィルムを交互に積層後、接着していたため、耐食
性、信頼性、量産性等について考慮されておらず、その
ため、ポリイミドフィルムの経年劣化による信頼性の低
下や接着強度が小さく、また、シース液に対して充分な
耐食性をもっておらず、さらに、ガラス製なので信頼性
の問題があった。In the conventional flow cell device described above, glass plates and polyimide films were laminated alternately and then bonded together, so corrosion resistance, reliability, mass production, etc. were not considered, and reliability was affected due to age-related deterioration of the polyimide film. The bonding strength was small, and it did not have sufficient corrosion resistance against the sheath liquid.Furthermore, since it was made of glass, there were problems with reliability.
本発明の目的は耐食性、信頼性、量産性にすぐれたフロ
ーセル装置を提供することにある。An object of the present invention is to provide a flow cell device with excellent corrosion resistance, reliability, and mass productivity.
上記目的を達成するために、本発明は加工性。 In order to achieve the above object, the present invention improves processability.
取扱い性のすぐれた鉄基合金薄板を用い、かつ、耐食性
のすぐれたＮｉ−Ｐメッキ層で接合すると共に、このメ
ッキ溶融層を流路表面に形成して信頼性、量産性を向上
させたものである。This product uses iron-based alloy thin plates with excellent handling properties and is joined with a Ni-P plating layer with excellent corrosion resistance, and this molten plating layer is formed on the flow path surface to improve reliability and mass production. It is.
Ｎｉ−Ｐメッキは、耐食性にすぐれている鉄基金属接合
用ろう材であり、このろう材を用いることによって各積
層板は強固に接合されると共に流路面にもメッキ溶融層
が形成されるため、従来法で問題となついた耐食性は向
上し、信頼性及び量産性が著しく向上する。Ni-P plating is a brazing material for joining iron-based metals that has excellent corrosion resistance. By using this brazing material, each laminate is firmly joined, and a molten plating layer is also formed on the flow path surface. Corrosion resistance, which was a problem with conventional methods, is improved, and reliability and mass productivity are significantly improved.
以下、本発明の一実施例を図により説明する。 Hereinafter, one embodiment of the present invention will be described with reference to the drawings.
［実施例１］ 第１図は本発明のフローセル装置の構造を示す。[Example 1] FIG. 1 shows the structure of the flow cell device of the present invention.
厚さ０ 、１ ｍ （７） Ｓ Ｕ Ｓ ３０４１〜５
Ｌニー流路６を形成したのち５ＵＳ３０４の表面粗さ
に応じて、金属表面を均一にｐＨ％のＮｉ−Ｐ無電解メ
ッキをする。たとえば、表面粗さが１μｍの場合はメッ
キ厚さ１μｍ、表面粗さが５μｍの場合は、メッキ厚さ
５μｍのメッキをする。このメッキされた５ＵＳ３０４
を積層後、１０−”Ｐ ａ程度の真空中でｐＨｗｔ％組
成のＮｉ−Ｐ融点８８０’Ｃがら７０℃高い温度である
９５０℃で９．８Ｘ１０５Ｐａの圧力で加圧しろう付す
る。この製法により得られたフローセル装置でろう付部
強度について試験をした結果、ろう付部強度は３８０
Ｍ Ｐ ａの強度が得られた。この強度は、ガラス板を
ポリイミドフィルムで接着させた場合の３０ Ｍ Ｐ
ａよりはるかに高い。さらに、耐食性について０．９％
生理食塩水、アクリジンオレンジ溶液中に３０日浸漬し
た結果、現状の医療機器で使用している５ＵＳ３０４よ
り耐食性にすぐれている５ＵＳ３１６と同様の耐食性を
示した。Thickness 0, 1 m (7) SUS 3041-5
After forming the L knee channel 6, the metal surface is uniformly electrolessly plated with Ni--P at pH% depending on the surface roughness of the 5US304. For example, if the surface roughness is 1 μm, the plating thickness is 1 μm, and if the surface roughness is 5 μm, the plating thickness is 5 μm. This plated 5US304
After laminating, they are brazed under a pressure of 9.8 x 105 Pa at 950°C, which is 70°C higher than the Ni-P melting point of 880'C with a pH wt% composition in a vacuum of about 10-''Pa.By this manufacturing method, As a result of testing the strength of the brazed part using the obtained flow cell device, the strength of the brazed part was 380.
An intensity of M Pa was obtained. This strength is 30 MP when glass plates are bonded with polyimide film.
much higher than a. Furthermore, 0.9% for corrosion resistance
As a result of immersion in physiological saline and acridine orange solution for 30 days, it showed corrosion resistance similar to that of 5US316, which has better corrosion resistance than 5US304 currently used in medical devices.
［実施例２］
流路６を形成した厚さ０．１ｍのコバール１〜５表面に
、厚さ１０ＩＬｍの無電解Ｎｉ−Ｐめつきをする。この
コバールを積層後、１Ｏ−３Ｐａの真空中でろう付温度
１０００℃，圧力９．８ Ｘ １０５Ｐａでろう付した
。このフローセル装置でメッキ厚さと表面粗さによるボ
イド発生の状況について検討した。その結果を第３図に
示す。図かられかるように表面粗さ以下のメッキ厚さで
は、接合界面にボイドが発生して流路中の液体が外周に
しみ出す。しかし、表面粗さ以上のメッキ厚さならボイ
ドを発生することなくろう付することができる。[Example 2] Electroless Ni-P plating with a thickness of 10 ILm is applied to the surface of Kovar 1 to 5 with a thickness of 0.1 m on which the flow path 6 is formed. After laminating this Kovar, brazing was performed in a vacuum of 10-3 Pa at a brazing temperature of 1000° C. and a pressure of 9.8×10 5 Pa. Using this flow cell device, we investigated the occurrence of voids due to plating thickness and surface roughness. The results are shown in FIG. As can be seen from the figure, if the plating thickness is less than the surface roughness, voids will occur at the bonding interface and the liquid in the flow path will seep out to the outer periphery. However, if the plating thickness is greater than the surface roughness, brazing can be performed without generating voids.
しかし、フローセルを切断し断面をｔＲ察したところメ
ッキ厚さが１５μｍでは、第２図に示すような形状でろ
う７が流路壁面にはみ出す。これにより流路を流れる溶
液に乱流が発生し、安定なシースフローが得られなかっ
た。However, when the flow cell was cut and the cross section was observed at tR, when the plating thickness was 15 μm, the wax 7 protruded from the flow channel wall surface in a shape as shown in FIG. This caused turbulence in the solution flowing through the channel, making it impossible to obtain a stable sheath flow.
本発明によれば、耐食性のＮｉ−Ｐメッキでろう付けす
るので、融溶したＮｉ−Ｐが流路を形成することにより
耐食性にすぐれたフローセル装置が得られる。According to the present invention, since brazing is performed using corrosion-resistant Ni-P plating, a flow cell device with excellent corrosion resistance can be obtained because the molten Ni-P forms a flow path.
また、ハンドリングの簡単であるメッキなので量産性が
あり、さらに、メッキを溶融しろう付することにより信
頼性のあるフローセル装置が得られる。Furthermore, since the plating is easy to handle, it can be mass-produced, and by melting and brazing the plating, a reliable flow cell device can be obtained.
第１図は、本発明の一実施例のフローセルの斜視図、第
２図は、フローセルの断面図、第３図は、素材粗さとメ
ッキ厚さの関係にょるボイド発生状況説明図である。
１〜５・・５ＵＳ３０４．６・・・流路。FIG. 1 is a perspective view of a flow cell according to an embodiment of the present invention, FIG. 2 is a sectional view of the flow cell, and FIG. 3 is an explanatory diagram of void occurrence depending on the relationship between material roughness and plating thickness. 1-5...5US304.6...Flow path.
Claims (1)
なることを特徴とするフローセル装置。 ２、請求項１において、前記Ｎｉ−Ｐメッキが１〜１０
μｍの厚さでメッキされろう付してなるフローセル装置
。 ３、請求項１において、前記Ｎｉ−Ｐメッキは、Ｐ１０
〜１２％、残部Ｎｉから成り、このメッキの融点直上か
ら、融点より１００℃高い温度の範囲でろう付けするフ
ローセル装置の製法。[Claims] 1. A flow cell device characterized in that it is formed by laminating and brazing Ni--P plated iron-based alloy thin plates. 2. In claim 1, the Ni-P plating is 1 to 10
A flow cell device plated and brazed to a thickness of μm. 3. In claim 1, the Ni-P plating is P10
~12%, the balance being Ni, and brazing at a temperature ranging from just above the melting point of this plating to 100°C higher than the melting point.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10759390A JPH046443A (en) | 1990-04-25 | 1990-04-25 | Flow cell device and manufacture thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10759390A JPH046443A (en) | 1990-04-25 | 1990-04-25 | Flow cell device and manufacture thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH046443A true JPH046443A (en) | 1992-01-10 |
Family
ID=14463092
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP10759390A Pending JPH046443A (en) | 1990-04-25 | 1990-04-25 | Flow cell device and manufacture thereof |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH046443A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05312717A (en) * | 1992-05-07 | 1993-11-22 | Jasco Corp | Optical cell |
| JPH05318640A (en) * | 1992-05-19 | 1993-12-03 | Sumitomo Bakelite Co Ltd | Laminated sheet |
-
1990
- 1990-04-25 JP JP10759390A patent/JPH046443A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05312717A (en) * | 1992-05-07 | 1993-11-22 | Jasco Corp | Optical cell |
| JPH05318640A (en) * | 1992-05-19 | 1993-12-03 | Sumitomo Bakelite Co Ltd | Laminated sheet |
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