JPH04299253A - Background remover for anion - Google Patents
Background remover for anionInfo
- Publication number
- JPH04299253A JPH04299253A JP6507491A JP6507491A JPH04299253A JP H04299253 A JPH04299253 A JP H04299253A JP 6507491 A JP6507491 A JP 6507491A JP 6507491 A JP6507491 A JP 6507491A JP H04299253 A JPH04299253 A JP H04299253A
- Authority
- JP
- Japan
- Prior art keywords
- sheet
- cation exchange
- substrate
- liquid
- anion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001450 anions Chemical class 0.000 title claims description 34
- 239000007788 liquid Substances 0.000 claims abstract description 30
- 238000005341 cation exchange Methods 0.000 claims abstract description 25
- 239000012528 membrane Substances 0.000 claims abstract description 21
- 239000000758 substrate Substances 0.000 claims abstract description 21
- 239000000126 substance Substances 0.000 claims abstract description 4
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 claims description 13
- 239000003729 cation exchange resin Substances 0.000 claims description 13
- 239000004372 Polyvinyl alcohol Substances 0.000 claims description 7
- 229920002451 polyvinyl alcohol Polymers 0.000 claims description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
- 239000003292 glue Substances 0.000 claims description 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 238000004513 sizing Methods 0.000 claims 2
- 229920002472 Starch Polymers 0.000 claims 1
- 239000011324 bead Substances 0.000 claims 1
- QXJJQWWVWRCVQT-UHFFFAOYSA-K calcium;sodium;phosphate Chemical compound [Na+].[Ca+2].[O-]P([O-])([O-])=O QXJJQWWVWRCVQT-UHFFFAOYSA-K 0.000 claims 1
- 239000002184 metal Substances 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 235000019698 starch Nutrition 0.000 claims 1
- 239000008107 starch Substances 0.000 claims 1
- 238000005342 ion exchange Methods 0.000 abstract description 12
- 239000002759 woven fabric Substances 0.000 abstract 1
- 238000000926 separation method Methods 0.000 description 11
- 239000003480 eluent Substances 0.000 description 10
- 239000000243 solution Substances 0.000 description 9
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
- 150000001768 cations Chemical class 0.000 description 3
- 239000000945 filler Substances 0.000 description 3
- 150000002500 ions Chemical class 0.000 description 3
- 125000006850 spacer group Chemical group 0.000 description 3
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000003014 ion exchange membrane Substances 0.000 description 2
- 238000012856 packing Methods 0.000 description 2
- 239000012488 sample solution Substances 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 229910001415 sodium ion Inorganic materials 0.000 description 2
- 235000011149 sulphuric acid Nutrition 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- 229910003556 H2 SO4 Inorganic materials 0.000 description 1
- 229910004809 Na2 SO4 Inorganic materials 0.000 description 1
- 239000004809 Teflon Substances 0.000 description 1
- 229920006362 Teflon® Polymers 0.000 description 1
- 239000012491 analyte Substances 0.000 description 1
- 239000003957 anion exchange resin Substances 0.000 description 1
- 239000003637 basic solution Substances 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-N carbonic acid Chemical compound OC(O)=O BVKZGUZCCUSVTD-UHFFFAOYSA-N 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- -1 hydrogen ions Chemical class 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000005192 partition Methods 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000000523 sample Substances 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
Landscapes
- Separation Using Semi-Permeable Membranes (AREA)
- Manufacture Of Macromolecular Shaped Articles (AREA)
Abstract
Description
【０００１】0001
【産業上の利用分野】本発明は、被測定液中の陰イオン
を分析する陰イオン分析装置に装着され、分離カラムか
らの溶出液あるいは試料溶液自身の導電率バックグラン
ドを減少させる陰イオン用バックグランド除去装置に関
する。[Industrial Application Field] The present invention is an anion analyzer that is installed in an anion analyzer for analyzing anions in a liquid to be measured, and is used to reduce the conductivity background of the eluate from a separation column or the sample solution itself. The present invention relates to a background removal device.
【０００２】0002
【従来の技術】一般に、被測定液中の陰イオンを分析す
るには、低交換容量の陰イオン交換樹脂が充填された分
離カラムに、希薄な塩基性溶液（例えば炭酸ナトリウム
や水酸化ナトリウム等）でなる移動相でもって一定量の
被測定液を搬送し該被測定液中の陰イオンをクロマトグ
ラフィックに分離させて分析を行うようになっていた。
また、被測定液中の陰イオンの検出は、分離カラムから
の溶出液を直接検出器（例えば導電率検出器）で検出し
、分析結果たるクロマトグラムを得ることによって行な
うことができる。[Prior Art] Generally, in order to analyze anions in a liquid to be measured, a dilute basic solution (such as sodium carbonate or sodium hydroxide) is added to a separation column packed with an anion exchange resin with a low exchange capacity. ) A fixed amount of the liquid to be measured is transported using a mobile phase, and the anions in the liquid to be measured are chromatographically separated for analysis. Further, anions in the liquid to be measured can be detected by directly detecting the eluate from the separation column with a detector (for example, a conductivity detector) and obtaining a chromatogram as an analysis result.
【０００３】しかし、分離カラムと検出器の間にＨ＋
型の陽イオン交換膜を利用したサプレッサを置き、該サ
プレッサに上記移動相（カラムからの溶出液）を通すこ
とによって移動相を導電率の低い液（例えば水や炭酸等
）にすると共に被測定液中の陰イオンの対イオンを水素
イオンに変えてのちに検出器で検出し分析結果たるクロ
マトグラムを得ることによっても行われる。即ち、この
ようにすることにより、移動相の導電率を低下させてＳ
／Ｎ比を向上させながら被測定液中の陰イオンを測定す
ることが行われる。However, H+ between the separation column and the detector
A suppressor using a type of cation exchange membrane is installed, and by passing the mobile phase (eluate from the column) through the suppressor, the mobile phase is made into a liquid with low conductivity (e.g. water, carbonic acid, etc.) and the sample to be measured is This can also be done by converting the counter ions of anions in the liquid into hydrogen ions, which are then detected by a detector to obtain a chromatogram as the analysis result. That is, by doing this, the conductivity of the mobile phase is reduced and S
Anions in the liquid to be measured are measured while improving the /N ratio.
【０００４】この場合、サプレッサは、通常、二重管構
造の陽イオン交換チューブでなるサプレッサが用いられ
る。これは、ステンレスあるいはテフロンチューブの中
にこれらのチューブの内径より細い外径を持つ中空の陽
イオン交換チューブを入れた二重管構造になっている。
また、カラムからの溶出液は中空の陽イオン交換チュー
ブの中を流れ、除去液はその外側を移動相の流れに対し
て向流で流れるようになっており、連続的にバックグラ
ンドを低減できるようになっている。[0004] In this case, the suppressor used is usually a cation exchange tube with a double tube structure. This has a double tube structure in which a hollow cation exchange tube with an outer diameter smaller than the inner diameter of these tubes is placed inside a stainless steel or Teflon tube. In addition, the eluate from the column flows through a hollow cation exchange tube, and the removal solution flows outside the tube in countercurrent to the flow of the mobile phase, allowing continuous background reduction. It looks like this.
【０００５】然しながら、上記サプレッサは中空の陽イ
オン交換チューブを利用しているためイオン交換効率は
あまり高くなくバックグランドを高い効率で減少させる
ことは難しい。従って、十分なサプレスト効果を得るた
めにはかなりの長さが必要となり、結果として内容積が
増加し余剰の分析時間を費やし、分離カラムで分離した
成分の広がりを生じてしまうという問題がある。この問
題の改善策として、内径の小さいイオン交換チューブを
使用することやイオン交換効率の高いイオン交換チュー
ブを利用することが考えられるが、このようなチューブ
は入手が非常に困難であるうえ、製作・加工に困難が伴
なうという問題もある。However, since the above suppressor uses a hollow cation exchange tube, the ion exchange efficiency is not very high and it is difficult to reduce the background with high efficiency. Therefore, in order to obtain a sufficient suppressing effect, a considerable length is required, resulting in an increase in internal volume, resulting in extra analysis time and the spread of the components separated in the separation column. Possible ways to improve this problem include using ion exchange tubes with a small inner diameter or ion exchange tubes with high ion exchange efficiency, but such tubes are extremely difficult to obtain and are difficult to manufacture.・There is also the problem that processing is difficult.
【０００６】また、上記サプレッサの欠点を改良したシ
ート状のイオン交換膜を利用した例としては、２枚の陽
イオン交換膜と球状充填物（例えば陽イオン交換樹脂）
が充填された長い溝を有する３枚のスペーサを積層した
ものなどが知られている。しかし、被測定液が流れる溝
に充填された球状物質（例えば、陽イオン交換樹脂）が
被測定液に押されて溝の一端に片寄り、陽イオン交換膜
を破損させたりイオン交換能を低下させたりするという
欠点があった。[0006] Also, as an example of using a sheet-like ion exchange membrane that improves the drawbacks of the above suppressor, there are two cation exchange membranes and a spherical filler (for example, a cation exchange resin).
A spacer stacked with three spacers each having a long groove filled with spacers is known. However, the spherical material (e.g., cation exchange resin) filled in the groove through which the liquid to be measured flows is pushed by the liquid to be measured and is biased toward one end of the groove, damaging the cation exchange membrane or reducing ion exchange performance. There was a drawback that it could cause
【０００７】本発明は、かかる従来例の欠点に鑑みてな
されたものであり、その目的は、入手が容易なシート状
の陽イオン交換膜，球状充填物，及び織り網状のシート
を用い、耐久性とイオン交換能に優れた簡単な構成の陰
イオン用バックグランド除去装置を提供することにある
。[0007] The present invention was made in view of the drawbacks of the conventional examples, and its purpose is to use easily available sheet-like cation exchange membranes, spherical packings, and woven net-like sheets, and to improve durability. An object of the present invention is to provide an anion background removing device having a simple structure and excellent performance and ion exchange ability.
【０００８】[0008]
【課題を解決するための手段】＜問題点を解決するため
の手段＞上述のような問題点を解決する本発明の特徴は
、被測定液中の陰イオンを分析する陰イオン分析装置に
装着され被測定液体の導電率バックグランドを減少させ
る陰イオン用バックグランド除去装置において、陽イオ
ン交換膜でなる第１シートと、球状物質を含浸した織り
網が充填された長い溝を有する第２シートと、陽イオン
交換膜でなる第３シートとを設け、前記第１〜第３のシ
―トを積層してその上下を前記第１シートと接する面に
長い溝を有する第１基板と前記第３シートと接する面に
長い溝を有する第２の基板で狭着し、前記第１及び第３
のシートに挟まれた第２シートの間隙流路に移動相を流
すと共に、前記第１シートと前記第１基板に挟まれ前記
第１シートの外側に形成された間隙流路及び前記第３シ
ートと前記第２基板に挟まれ前記第３シートの外側に形
成された間隙流路に除去液を流すようにしたことにある
。[Means for Solving the Problems] <Means for Solving the Problems> The feature of the present invention that solves the above-mentioned problems is that it is attached to an anion analyzer that analyzes anions in a liquid to be measured. A background removal device for anions that reduces the conductivity background of a liquid to be measured includes a first sheet made of a cation exchange membrane and a second sheet having long grooves filled with a woven mesh impregnated with a spherical substance. and a third sheet made of a cation exchange membrane, the first to third sheets are laminated, and the first substrate has a long groove on its top and bottom surfaces in contact with the first sheet; A second substrate having a long groove on the surface in contact with the third sheet is used to narrowly bond the first and third sheets.
The mobile phase is caused to flow through the gap flow path of the second sheet sandwiched between the sheets, and the gap flow path formed outside the first sheet sandwiched between the first sheet and the first substrate and the third sheet. The removal liquid is made to flow through a gap flow path formed on the outside of the third sheet sandwiched between the second substrate and the third sheet.
【０００９】[0009]
【作用】本発明は次のように作用する。即ち、２枚の陽
イオン交換膜で仕切られた３つの部屋（例えば、部屋Ｃ
１ 、Ｃ２ 、Ｃ３ ）には例えば陽イオン交換樹脂の
ような球状充填物が充填されており、無駄体積は少なく
なっている。また、部屋Ｃ２ には分離カラムから溶出
された被測定成分（例えばＣｌ− イオン）を含む溶離
液や被測定溶液（例えばＮａＣｌを含むＮａＯＨ）が流
れ、部屋Ｃ１ 、Ｃ３ には該溶離液と向流方向に除去
液（例えば Ｈ２ ＳＯ４ ）が流れている。[Operation] The present invention operates as follows. That is, there are three rooms (for example, room C) separated by two cation exchange membranes.
1, C2, C3) are filled with a spherical filler such as a cation exchange resin, and the wasted volume is reduced. In addition, an eluent containing a component to be measured (e.g., Cl- ion) and a solution to be measured (e.g., NaOH containing NaCl) flowing from the separation column flow into the room C2, and a flow opposite to the eluent flows into the rooms C1 and C3. A removal liquid (eg H2SO4) is flowing in the flow direction.
【００１０】この状態で、部屋Ｃ２ 内の分離カラムか
らの溶離液や被測定溶液（例えばＮａＣｌを含むＮａＯ
Ｈ）に含まれているＮａ＋ イオンは、部屋Ｃ１ 、Ｃ
３ 内の除去液（例えばＨ２ ＳＯ４ ）に含まれてい
る Ｈ＋ イオンと陽イオン交換膜を介してイオン交換
する。この時、分離カラムからの溶離液や被測定溶液中
の被測定成分（例えばＣｌ− イオン）は各部屋を仕切
る陽イオン交換膜と同一の電荷を持つためイオン交換さ
れずに部屋Ｃ２ 中に残る。このため、部屋Ｃ２ から
溶出する液体は、イオン交換されて対イオンが Ｈ＋
型となった被測定成分（例えば ＨＣｌ）を含む導電率
のバックグランドの除去された液体（例えば Ｈ２ Ｏ
）となり、部屋Ｃ１ 、Ｃ３ から溶出する液体は、
溶離液や被測定溶液中の陽イオンとイオン交換して例え
ばＮａ＋ 型になった除去液（例えばＮａ２ ＳＯ４
）と余剰の除去液（例えば Ｈ２ ＳＯ４ ）を含む導
電率の高い液体となる。In this state, the eluent from the separation column in the room C2 or the solution to be measured (for example, NaO containing NaCl) is
The Na+ ions contained in H) are in rooms C1 and C
3. Ion exchange is performed with H+ ions contained in the removal solution (for example, H2 SO4) through a cation exchange membrane. At this time, the eluent from the separation column and the components to be measured (e.g. Cl- ions) in the solution to be measured remain in room C2 without being ion-exchanged because they have the same charge as the cation exchange membrane that partitions each room. . Therefore, the liquid eluted from chamber C2 undergoes ion exchange and the counter ion becomes H+
Conductivity background-removed liquid (e.g. H2O) containing the analyte (e.g. HCl) in the form of a
), and the liquid eluted from chambers C1 and C3 is
A removal solution that undergoes ion exchange with the cations in the eluent or sample solution to become, for example, Na+ type (e.g., Na2 SO4
) and excess removal liquid (for example, H2SO4).
【００１１】[0011]
【実施例】以下、本発明について図を用いて詳細に説明
する。第１図は本発明実施例の分解構成斜視図である。
この図において、１は例えばアクリル板でなる第１基板
、１ａは中央に設けられた溝、１ａ１ 〜１ａ１０は第
１基板に設けられた貫通穴、１ｂ１ は貫通穴１ａ１
に挿入されるボルト、１ｃは溶離液用の導入口、１ｄは
除去液用の第１導入口、１ｅは溶離液用の導出口、１ｆ
は除去液用の第１導出口、２はシート状の陽イオン交換
膜でなる第１シート、３は中央部に溝３ａが設けられた
例えばゴム製の第２シート、４はシート状の陽イオン交
換膜でなる第３シート、５は例えばアクリル板でなる第
２基板、５ａは中央に設けられた溝、５ａ１ 〜５ａ１
０は第２基板５に設けられた貫通穴、５ｃは除去液用の
第２導入口、５ｄは除去液用の第２導出口、６ａ１ は
ワッシャ、６ｂ１ はボルト１ｂ１ のネジ部と合うナ
ットである。
尚、第１基板の溝１ａ、第２シートの溝２ａ、及び第２
基板の溝５ａには、いずれも球状充填物あるいは織り網
状のシート例えば陽イオン交換樹脂が充填されている。DESCRIPTION OF THE PREFERRED EMBODIMENTS The present invention will be explained in detail below with reference to the drawings. FIG. 1 is an exploded perspective view of an embodiment of the present invention. In this figure, 1 is a first substrate made of, for example, an acrylic plate, 1a is a groove provided in the center, 1a1 to 1a10 are through holes provided in the first substrate, and 1b1 is a through hole 1a1.
1c is the inlet for the eluent, 1d is the first inlet for the removal liquid, 1e is the outlet for the eluent, 1f
2 is a first sheet made of a sheet-shaped cation exchange membrane; 3 is a second sheet made of rubber, for example, and has a groove 3a in the center; 4 is a sheet-shaped cation exchange membrane; A third sheet made of an ion exchange membrane, 5 a second substrate made of, for example, an acrylic plate, 5a a groove provided in the center, 5a1 to 5a1
0 is a through hole provided in the second substrate 5, 5c is a second inlet for the removal liquid, 5d is a second outlet for the removal liquid, 6a1 is a washer, and 6b1 is a nut that fits with the threaded part of the bolt 1b1. be. Note that the groove 1a of the first substrate, the groove 2a of the second sheet, and the
Each of the grooves 5a of the substrate is filled with a spherical filler or a woven mesh sheet, such as a cation exchange resin.
【００１２】ところで、陽イオン交換樹脂が充填された
織り網状シ―ト３ｂはつぎのようにして作製される。即
ち、最初、ポリビニルアルコ―ルを温水に２〜５％程度
の濃度となるように溶解し、このポリビニルアルコ―ル
水溶液１０ｍｌに１００〜２００メッシュ程度の陽イオ
ン交換樹脂を少量均一に分散させる。次に、織り網状の
シ―トの上に陽イオン交換樹脂を分散させたポリビニル
アロコ―ル水溶液を所定量のせる。By the way, the woven mesh sheet 3b filled with cation exchange resin is produced as follows. That is, first, polyvinyl alcohol is dissolved in warm water to a concentration of about 2 to 5%, and a small amount of a cation exchange resin of about 100 to 200 mesh is uniformly dispersed in 10 ml of this polyvinyl alcohol aqueous solution. Next, a predetermined amount of a polyvinyl alcohol aqueous solution in which a cation exchange resin is dispersed is placed on the woven net-like sheet.
【００１３】その後、このシ―トを空中で保持し、陽イ
オン交換樹脂を分散させたポリビニルアルコ―ル水溶液
を含浸させ、自然乾燥させる。このようにして、陽イオ
ン交換樹脂を分散させたポリビニルアルコ―ル水溶液を
含浸させた織り網状のシ―トは、第１図に示すようなバ
ックグランド除去装置として組み立てられる。組み立て
が完了して後、溶離液の導入口から水を０．２ｍｌ〜０
．５ｍｌ程度の流量で１２時間以上流し、ポリビニルア
ルコ―ルを除去する。[0013] Thereafter, this sheet is held in air, impregnated with an aqueous polyvinyl alcohol solution in which a cation exchange resin is dispersed, and then air-dried. In this way, a woven net-like sheet impregnated with an aqueous polyvinyl alcohol solution in which a cation exchange resin is dispersed is assembled as a background removing device as shown in FIG. After the assembly is completed, add 0.2ml to 0.0ml of water from the eluent inlet.
．． The polyvinyl alcohol is removed by flowing the solution at a flow rate of about 5 ml for 12 hours or more.
【００１４】一方、第１図のような分解構成からなる本
発明の実施例は、第１〜第３のシート２〜４が積層され
てのち該シート２〜４が第１及び第２の基板１及び５で
挟まれ、その後ボルト１ｂ１ （及び図示しないボルト
１ｂ２ 〜１ｂ１０）が貫通穴１ａ１ （及び１ａ２
〜１ａ１０）と貫通穴５ａ１ （及び５ａ２ 〜５ａ１
０）の貫通されてのちワッシャ６ａ１ （及び図示しな
いワッシャ６ａ２ 〜６ａ１０）が入れられ、最後にボ
ルト１ｂ１ （及び１ｂ２ 〜１ｂ１０）のネジ部にナ
ット６ｂ１ （及び図示しないナット６ｂ２ 〜６ｂ１
０）がねじ込まれることによって、本発明実施例たる陰
イオン用バックグランド除去装置の組立が完成する。On the other hand, in the embodiment of the present invention which has an exploded configuration as shown in FIG. 1 and 5, and then bolt 1b1 (and bolts 1b2 to 1b10 (not shown)) are inserted into through hole 1a1 (and 1a2
~1a10) and through hole 5a1 (and 5a2 ~5a1
0), a washer 6a1 (and washers 6a2 to 6a10, not shown) is inserted, and finally a nut 6b1 (and nuts 6b2 to 6b1, not shown) is inserted into the threaded portion of the bolt 1b1 (and 1b2 to 1b10).
0), the assembly of the anion background removing device according to the embodiment of the present invention is completed.
【００１５】このようにして組み立てられた陰イオン用
バックグランド除去装置は第２図に示すような陰イオン
分析装置に装着されて使用される。即ち、第２図は本発
明実施例の使用例構成説明図であり、図中、分離カラム
１０、サプレッサ１１、及び検出器１２は恒温槽１３内
に収容されて一定温度（例えば４５℃）に保たれている
。The anion background removing device assembled in this manner is used by being attached to an anion analyzer as shown in FIG. That is, FIG. 2 is an explanatory diagram of the configuration of an example of use of the embodiment of the present invention, in which the separation column 10, suppressor 11, and detector 12 are housed in a constant temperature bath 13 and kept at a constant temperature (for example, 45° C.). It is maintained.
【００１６】また、ポンプ８ａが駆動すると槽７ａ内の
溶離液が、例えば１ｍｌ／ｍｉｎ の流量で、ポンプ８
ａ→切換弁９の第１及び第２の接続口９ａ、９ｂ→分離
カラム１０→陰イオン用バックグランド除去装置１１の
内室１１ｂの導入口１ｃ→陰イオン用バックグランド除
去装置１１の内室１１ｂ→陰イオン用バックグランド除
去装置１１の内室１１ｂの導出口１ｅ→検出器１２を経
て廃液槽７ｃへと流れ、ポンプ７ｂが駆動すると槽７ｂ
内の除去液が、例えば１ｍｌ／ｍｉｎ．の流量で、ポン
プ７ｂ→陰イオン用バックグランド除去装置１１の外室
１１ｃの第１導入口１ｄ→陰イオン用バックグランド除
去装置１１の外室１１ｃ→陰イオン用バックグランド除
去装置１１の外室１１ｃの第１導出口１ｆ→陰イオン用
バックグランド除去装置１１の外室１１ｃの第２導入口
５ｃ→陰イオン用バックグランド除去装置１１の外室１
１ｃ→陰イオン用バックグランド除去装置１１の外室１
１ｃの第２導出口５ｄを経て廃液槽７ｄへと流れる。Further, when the pump 8a is driven, the eluent in the tank 7a is pumped at a flow rate of, for example, 1 ml/min.
a→first and second connection ports 9a, 9b of switching valve 9→separation column 10→inlet 1c of interior chamber 11b of anion background removal device 11→inner chamber of anion background removal device 11 11b → Outlet 1e of the inner chamber 11b of the anion background removal device 11 → Flows through the detector 12 to the waste tank 7c, and when the pump 7b is driven, the tank 7b
For example, the removal liquid inside is 1 ml/min. At a flow rate of pump 7b→first inlet 1d of outer chamber 11c of anion background removal device 11→outer chamber 11c of anion background removal device 11→outer chamber of anion background removal device 11 11c first outlet 1f→second inlet 5c of anion background removing device 11 outer chamber 11c→anion background removing device 11 outer chamber 1
1c → Outer chamber 1 of anion background removal device 11
It flows into the waste liquid tank 7d via the second outlet 5d of the liquid 1c.
【００１７】このため、陰イオン用バックグランド除去
装置１１の内室１１ｂ（第１図の溝４ａ）内を流れる液
体に含まれている陽イオンは陽イオン交換膜１１ａ（第
１図の第１シート２及び第３シート４）を介して陰イオ
ン用バックグランド除去装置１１の外室１１ｃ（第１図
の溝１ａ及び溝５ａ）内を流れる液体に含まれている陽
イオンと交換し究極的に陰イオン分析におけるバックグ
ランド導電率を低下させることができるようになる。
尚、本発明は上述の実施例に限定されることなく種々の
変形が可能である。Therefore, the cations contained in the liquid flowing in the inner chamber 11b (groove 4a in FIG. 1) of the anion background removal device 11 are removed by the cation exchange membrane 11a (groove 4a in FIG. 1). The cations contained in the liquid flowing in the outer chamber 11c (grooves 1a and 5a in FIG. 1) of the background removing device 11 for anions are exchanged through This makes it possible to reduce the background conductivity in anion analysis. Note that the present invention is not limited to the above-described embodiments, and can be modified in various ways.
【００１８】[0018]
【発明の効果】以上詳しく説明したような本発明の実施
例によれば、入手が容易なシート状の陽イオン交換膜，
球状充填物，織り網状のシート，及び水溶性の糊剤など
を用い、デッドボリウムの小さな簡単な構成で、しかも
、耐久性とイオン交換能に優れた陰イオン用バックグラ
ンド除去装置が実現する。また、第１図において、第２
シ―ト３の溝３ａに充填されている陽イオン交換樹脂が
含浸された織り網状のシ―ト３ｂは、陽イオン交換膜２
，４をバックアップして溶離液が流れる流通系の耐圧を
高めるうえ、従来の陽イオン交換樹脂が直接第２シ―ト
３の溝３ａに充填されたサプレッサに比し、充填された
陽イオン交換樹脂が溝３ａの中で殆ど移動せず、そのた
めにイオン交換能と耐久性を著しく向上させる利点もあ
る。Effects of the Invention According to the embodiments of the present invention as described in detail above, the sheet-like cation exchange membrane, which is easily available,
By using a spherical packing, a woven mesh sheet, a water-soluble glue, etc., an anion background removal device with a simple structure with a small dead volume and excellent durability and ion exchange ability is realized. Also, in Figure 1, the second
A woven net-like sheet 3b impregnated with a cation exchange resin, which is filled in the grooves 3a of the sheet 3, is a cation exchange membrane 2.
, 4 to increase the pressure resistance of the flow system through which the eluent flows, and compared to the conventional suppressor in which the cation exchange resin is directly filled into the groove 3a of the second sheet 3, the suppressor filled with the cation exchange resin There is also the advantage that the resin hardly moves within the grooves 3a, thereby significantly improving ion exchange ability and durability.
【図１】本発明実施例の分解構成斜視図である。FIG. 1 is an exploded perspective view of an embodiment of the present invention.
【図２】本発明実施例の使用例説明図である。
１ 第１基板
１ａ，５ａ 溝
１ａ１ 〜１ａ１０ 貫通穴
１ｂ１ ボルト
１ｃ，１ｄ 導入口
１ｅ，１ｆ 導出口
２ シート状の陽イオン交換膜でなる第１シート３
中央部に溝が設けられた第２シート４ シート状の
陽イオン交換膜でなる第３シート５ 第２基板
５ａ１ 〜５ａ１０ 貫通穴
５ｃ，５ｄ 導入口
６ａ１ ワッシャ
６ｂ１ ナット
７ａ〜７ｄ 槽
８ａ，８ｂ ポンプ
９ 切換弁
１０ 分離カラム
１１ サプレッサ
１２ 検出器
１３ 恒温槽FIG. 2 is an explanatory diagram of an example of use of the embodiment of the present invention. 1 First substrates 1a, 5a Grooves 1a1 to 1a10 Through holes 1b1 Bolts 1c, 1d Inlets 1e, 1f Outlets 2 First sheet 3 made of a sheet-shaped cation exchange membrane
Second sheet 4 with a groove in the center Third sheet 5 made of a sheet-like cation exchange membrane Second substrate 5a1 to 5a10 Through holes 5c, 5d Inlet 6a1 Washer 6b1 Nuts 7a to 7d Tanks 8a, 8b Pump 9 Selector valve 10 Separation column 11 Suppressor 12 Detector 13 Constant temperature bath
Claims (2)
分析装置に装着され被測定液体の導電率バックグランド
を減少させる陰イオン用バックグランド除去装置におい
て、陽イオン交換膜でなる第１シートと、球状物質を含
浸した織り網が充填された長い溝を有する第２シートと
、陽イオン交換膜でなる第３シートとを具備し、前記第
１〜第３のシ―トを積層してその上下を前記第１シート
と接する面に長い溝を有する第１基板と前記第３シート
と接する面に長い溝を有する第２の基板で狭着し、前記
第１及び第３のシートに挟まれた第２シートの間隙流路
に移動相を流すと共に、前記第１シートと前記第１基板
に挟まれ前記第１シートの外側に形成された間隙流路及
び前記第３シートと前記第２基板に挟まれ前記第３シー
トの外側に形成された間隙流路に除去液を流すことを特
徴とする陰イオン用バックグランド除去装置。Claim 1: An anion background removal device that is attached to an anion analyzer for analyzing anions in a liquid to be measured and reduces the conductivity background of the liquid to be measured, wherein a first a second sheet having long grooves filled with a woven net impregnated with a spherical substance, and a third sheet made of a cation exchange membrane, and the first to third sheets are laminated. The top and bottom of the substrate are sandwiched between a first substrate having a long groove on the surface in contact with the first sheet and a second substrate having a long groove on the surface in contact with the third sheet, and the first and third sheets are bonded to each other. The mobile phase is caused to flow through the gap channel of the sandwiched second sheet, and the gap channel formed between the first sheet and the first substrate and formed on the outside of the first sheet, and between the third sheet and the third sheet. A background removal device for anions, characterized in that a removal liquid is caused to flow through a gap flow path formed on the outside of the third sheet sandwiched between two substrates.
が、陽イオン交換樹脂、ポリマービーズ、ガラス球、若
しくは金属球を、ポリビニルアルコ―ル、澱粉などの水
溶性糊剤に分散させて織り網に含浸させたのち糊剤を水
で溶かして除去したものでなる請求項１記載の陰イオン
用バックグランド除去装置。2. The long grooves of the second sheet are filled with cation exchange resin, polymer beads, glass spheres, or metal spheres dispersed in a water-soluble glue such as polyvinyl alcohol or starch. 2. The background removing device for anions according to claim 1, wherein the sizing agent is removed by impregnating a woven net with water and dissolving the sizing agent in water.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6507491A JPH04299253A (en) | 1991-03-28 | 1991-03-28 | Background remover for anion |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6507491A JPH04299253A (en) | 1991-03-28 | 1991-03-28 | Background remover for anion |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH04299253A true JPH04299253A (en) | 1992-10-22 |
Family
ID=13276444
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP6507491A Pending JPH04299253A (en) | 1991-03-28 | 1991-03-28 | Background remover for anion |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH04299253A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004508550A (en) * | 2000-09-08 | 2004-03-18 | ダウ グローバル テクノロジーズ インコーポレーテッド | Sequential detection ion chromatography |
-
1991
- 1991-03-28 JP JP6507491A patent/JPH04299253A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004508550A (en) * | 2000-09-08 | 2004-03-18 | ダウ グローバル テクノロジーズ インコーポレーテッド | Sequential detection ion chromatography |
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