JPH04154719A - Athlete's foot drug - Google Patents
Athlete's foot drugInfo
- Publication number
- JPH04154719A JPH04154719A JP2279165A JP27916590A JPH04154719A JP H04154719 A JPH04154719 A JP H04154719A JP 2279165 A JP2279165 A JP 2279165A JP 27916590 A JP27916590 A JP 27916590A JP H04154719 A JPH04154719 A JP H04154719A
- Authority
- JP
- Japan
- Prior art keywords
- athlete
- foot
- therapeutic agent
- thymol
- menthol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- BWMISRWJRUSYEX-SZKNIZGXSA-N terbinafine hydrochloride Chemical compound Cl.C1=CC=C2C(CN(C\C=C\C#CC(C)(C)C)C)=CC=CC2=C1 BWMISRWJRUSYEX-SZKNIZGXSA-N 0.000 title claims abstract description 22
- 201000004647 tinea pedis Diseases 0.000 title claims abstract description 22
- 239000003814 drug Substances 0.000 title claims abstract description 18
- 229940079593 drug Drugs 0.000 title description 5
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims abstract description 12
- OSWPMRLSEDHDFF-UHFFFAOYSA-N methyl salicylate Chemical compound COC(=O)C1=CC=CC=C1O OSWPMRLSEDHDFF-UHFFFAOYSA-N 0.000 claims abstract description 10
- MGSRCZKZVOBKFT-UHFFFAOYSA-N thymol Chemical compound CC(C)C1=CC=C(C)C=C1O MGSRCZKZVOBKFT-UHFFFAOYSA-N 0.000 claims abstract description 10
- RGOVYLWUIBMPGK-UHFFFAOYSA-N nonivamide Chemical compound CCCCCCCCC(=O)NCC1=CC=C(O)C(OC)=C1 RGOVYLWUIBMPGK-UHFFFAOYSA-N 0.000 claims abstract description 8
- 241001116389 Aloe Species 0.000 claims abstract description 5
- 240000004460 Tanacetum coccineum Species 0.000 claims abstract description 5
- 239000005844 Thymol Substances 0.000 claims abstract description 5
- ROVGZAWFACYCSP-MQBLHHJJSA-N [2-methyl-4-oxo-3-[(2z)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1r,3r)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate Chemical compound CC1(C)[C@H](C=C(C)C)[C@H]1C(=O)OC1C(C)=C(C\C=C/C=C)C(=O)C1 ROVGZAWFACYCSP-MQBLHHJJSA-N 0.000 claims abstract description 5
- 235000011399 aloe vera Nutrition 0.000 claims abstract description 5
- 229960001047 methyl salicylate Drugs 0.000 claims abstract description 5
- 239000000843 powder Substances 0.000 claims abstract description 5
- 229940015367 pyrethrum Drugs 0.000 claims abstract description 5
- 229960000790 thymol Drugs 0.000 claims abstract description 5
- DBAKFASWICGISY-BTJKTKAUSA-N Chlorpheniramine maleate Chemical compound OC(=O)\C=C/C(O)=O.C=1C=CC=NC=1C(CCN(C)C)C1=CC=C(Cl)C=C1 DBAKFASWICGISY-BTJKTKAUSA-N 0.000 claims abstract description 4
- 229940046978 chlorpheniramine maleate Drugs 0.000 claims abstract description 4
- NOOLISFMXDJSKH-KXUCPTDWSA-N (-)-Menthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@H]1O NOOLISFMXDJSKH-KXUCPTDWSA-N 0.000 claims abstract 3
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 claims abstract 3
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims abstract 3
- 235000011389 fruit/vegetable juice Nutrition 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 4
- 238000000034 method Methods 0.000 abstract description 2
- 229940124597 therapeutic agent Drugs 0.000 abstract 4
- 230000003902 lesion Effects 0.000 abstract 2
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 239000000052 vinegar Substances 0.000 abstract 1
- 235000021419 vinegar Nutrition 0.000 abstract 1
- 238000005406 washing Methods 0.000 abstract 1
- TZZAKSLHHIJRLL-UHFFFAOYSA-N 4-hydroxy-3-methoxybenzamide Chemical compound COC1=CC(C(N)=O)=CC=C1O TZZAKSLHHIJRLL-UHFFFAOYSA-N 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 208000007848 Alcoholism Diseases 0.000 description 1
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 description 1
- 201000007930 alcohol dependence Diseases 0.000 description 1
- 229960000846 camphor Drugs 0.000 description 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 description 1
- 239000011976 maleic acid Substances 0.000 description 1
- 229940041616 menthol Drugs 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000002547 new drug Substances 0.000 description 1
- FBUKVWPVBMHYJY-UHFFFAOYSA-N nonanoic acid Chemical compound CCCCCCCCC(O)=O FBUKVWPVBMHYJY-UHFFFAOYSA-N 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
Abstract
Description
【発明の詳細な説明】
［産業上の利用分野］
本発明は、いわゆる水虫（汗庖状白癖）の治療に用いる
薬に関する。DETAILED DESCRIPTION OF THE INVENTION [Industrial Field of Application] The present invention relates to a drug used for the treatment of so-called athlete's foot (alcoholism).
［従来の技術］及び
［発明が解決しようとする課題］
従来、水虫治療薬は多種製造されてきたが、いずれも水
虫を完全に治療することができるものではなかった。か
かる従来の水虫治療薬の寅情を鑑みて、本発明はなされ
たものであり、より完璧に水虫を治療するための新たな
薬を提供することが本発明の目的である。[Prior Art] and [Problems to be Solved by the Invention] Conventionally, various drugs for treating athlete's foot have been produced, but none of them can completely treat athlete's foot. The present invention was made in view of the current situation with conventional drugs for treating athlete's foot, and an object of the present invention is to provide a new drug for more completely treating athlete's foot.
［課題を解決するための手段］ 上記目的は、請求項に記載された水虫薬、すなわち、 サルチル酸メチル ６０００ｍｇ。[Means to solve the problem] The above object is achieved by the athlete's foot medicine as defined in the claims, namely: Methyl salicylate 6000mg.
ｉ−メントール ６２４０ｍｇ、ｄ２−カ
ンフル ６２４０ｍｇ、マレイン酸クロル
フェニラミン １２０ｍｇ、チモール
８４０ｍｇ。i-menthol 6240mg, d2-camphor 6240mg, chlorpheniramine maleate 120mg, thymol
840mg.
ノニル酸ワニリルアミド 、１２ｍｇと除虫菊
乾燥粉末１４ｇを酢酸３８０〜４００ｍβ中に混合し、
さらにアロエの葉１枚分の絞り汁を加えてなる水虫薬に
よって、達成される。12 mg of nonylic acid vanillylamide and 14 g of dried pyrethrum powder were mixed in 380-400 mβ of acetic acid,
This can also be achieved by using an athlete's foot medicine made by adding the juice of one aloe leaf.
［実施例］
酢酸３８０ｍｔｌ中に、サルチル酸メチル６０００ｍｇ
、 １２−ｙｌントール６２４０ｍｇ、 ｄ４２−カン
ル６２４０ｍｇ、マレイン酸りロルフェニラミ１２０ｍ
ｇ、チモール８４０ｍｇ、ノニル酸ワニルアミト１２ｍ
ｇを加え、良く攪拌、混合し、そ２に除虫菊乾燥粉末１
４ｇを投入、撹拌して混合−る、さらにアロエの葉１枚
分の絞り汁を加えて、ノ発明の水虫薬を得る。好ましく
は、この水虫薬を岸６０時間太陽光線に当てると良い。[Example] 6000 mg of methyl salicylate in 380 ml of acetic acid
, 12-yl nthol 6240mg, d42-kanru 6240mg, maleic acid lorphenirami 120m
g, thymol 840mg, nonylic acid vanillamide 12m
Add 1 g of pyrethrum dry powder and stir well to mix.
Add 4g of the mixture, stir to mix, and add the juice of one aloe leaf to obtain the athlete's foot medicine of the invention. Preferably, this athlete's foot medicine should be exposed to sunlight for 60 hours.
水虫薬を付ける前には２湯または水をもって、ｈ部を洗
うと治療効果が向上する０次いで、湯気がｄる程度に暖
めた酢を洗面器等の答器に溜め、患部（十分に酢に浸す
ことを数回繰り返す、その後に、Δ発明の水虫薬を付け
ると、水虫の治療効果が高くξる。かかる用法で、毎日
２回、朝と晩に行い、約１ケ月続けると、著しく水虫が
治る。なお、この治嗣の期間は、石鹸を患部にけっして
付けないように８意しなければならない。Before applying athlete's foot medicine, wash the affected area with hot water or cold water to improve the treatment effect. If you repeat soaking in water several times and then apply the athlete's foot medicine invented by Δ, the treatment effect for athlete's foot is highly ξ.If you use this method twice a day, in the morning and evening, for about a month, you will notice a noticeable effect. Athlete's foot will be cured. During this period of treatment, you must refrain from applying soap to the affected area.
この水虫薬の作用原理は現在のところ明らかでローない
が、乾性の水虫患者５０名に上記の用法で本磐明の水虫
薬を用いたところ約４０名が治り、また、７ ｐ性
の水虫患者３０名に上記の用法で本発明の水虫ン 薬
を用いたところ約２４名が治り、水虫治療の効果）
が大きいことがわかった。The principle of action of this athlete's foot medicine is not clear at present, but when Akira Motowa's athlete's foot medicine was used in the above manner on 50 patients with dry athlete's foot, about 40 people were cured. When the athlete's foot drug of the present invention was used on 30 patients in the above-mentioned manner, approximately 24 patients were cured (effect of athlete's foot treatment)
was found to be large.
「 ９ 特許出願人 菊 池 寛ジ 〔" 9 Patent applicant Hiroji Kikuike [
Claims (1)
４０ｍｇ、 ノニル酸ワニリルアミド１２ｍｇと 除虫菊乾燥粉末１４ｇを酢酸３８０〜４００ｍｌ中に混
合し、さらにアロエの葉１枚分の絞り汁を加えてなる水
虫薬。[Claims] 1 6000 mg of methyl salicylate, 6240 mg of l-menthol, 6240 mg of dl-camphor, 120 mg of chlorpheniramine maleate, 8 thymol
An athlete's foot medicine prepared by mixing 12 mg of nonylic acid vanillylamide and 14 g of dried pyrethrum powder in 380 to 400 ml of acetic acid, and adding the squeezed juice of one aloe leaf.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2279165A JPH04154719A (en) | 1990-10-19 | 1990-10-19 | Athlete's foot drug |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2279165A JPH04154719A (en) | 1990-10-19 | 1990-10-19 | Athlete's foot drug |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH04154719A true JPH04154719A (en) | 1992-05-27 |
Family
ID=17607359
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2279165A Pending JPH04154719A (en) | 1990-10-19 | 1990-10-19 | Athlete's foot drug |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH04154719A (en) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998000168A1 (en) * | 1996-07-02 | 1998-01-08 | Novartis Consumer Health S.A. | Topical composition comprising a combination of antihistaminic compounds with terpenoid compounds |
| EP1634500A3 (en) * | 1998-07-28 | 2006-08-09 | Ecosmart Technologies Inc. | Synergistic and residual pesticidal compositions containing plant essentials oils |
| US7250175B2 (en) | 1998-07-28 | 2007-07-31 | Ecosmart Technologies, Inc. | Synergistic and residual pesticidal compositions containing plant essential oils |
| EP1779729A3 (en) * | 1998-07-28 | 2007-09-05 | EcoSmart Technologies Inc. | Synergistic and residual pesticidal compositions containing plant essential oils |
| JP2008514596A (en) * | 2004-09-24 | 2008-05-08 | ミシガン ステイト ユニバーシティー | Composition without carrier for the treatment of onychomycosis |
| CN103301268A (en) * | 2013-06-13 | 2013-09-18 | 中国人民解放军海军总医院 | Ointment for jellyfish sting and preparation method thereof |
| US8920864B2 (en) | 2005-08-12 | 2014-12-30 | Takasago International Corporation | Sensation masking composition |
-
1990
- 1990-10-19 JP JP2279165A patent/JPH04154719A/en active Pending
Cited By (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998000168A1 (en) * | 1996-07-02 | 1998-01-08 | Novartis Consumer Health S.A. | Topical composition comprising a combination of antihistaminic compounds with terpenoid compounds |
| US7476397B2 (en) | 1998-07-28 | 2009-01-13 | Ecosmart Technologies, Inc. | Synergistic and residual pesticidal compositions containing plant essential oils |
| US7531189B2 (en) | 1998-07-28 | 2009-05-12 | Ecosmart Technologies, Inc. | Synergistic and residual pesticidal compositions containing plant essential oils |
| EP1779729A3 (en) * | 1998-07-28 | 2007-09-05 | EcoSmart Technologies Inc. | Synergistic and residual pesticidal compositions containing plant essential oils |
| US7320966B2 (en) | 1998-07-28 | 2008-01-22 | Ecosmart Technologies, Inc. | Synergistic and residual pesticidal compositions containing plant essential oils |
| US7351420B2 (en) | 1998-07-28 | 2008-04-01 | Ecosmart Technologies, Inc. | Synergistic and residual pesticidal compositions containing plant essential oils |
| US7361366B2 (en) | 1998-07-28 | 2008-04-22 | Ecosmart Technologies, Inc. | Synergistic and residual pesticidal compositions containing plant essential oils |
| US7250175B2 (en) | 1998-07-28 | 2007-07-31 | Ecosmart Technologies, Inc. | Synergistic and residual pesticidal compositions containing plant essential oils |
| EP1634500A3 (en) * | 1998-07-28 | 2006-08-09 | Ecosmart Technologies Inc. | Synergistic and residual pesticidal compositions containing plant essentials oils |
| US7618645B2 (en) | 1998-07-28 | 2009-11-17 | Ecosmart Technologies, Inc. | Synergistic and residual pesticidal compositions containing plant essential oils |
| US7534447B2 (en) | 1998-07-28 | 2009-05-19 | Ecosmart Technologies, Inc. | Synergistic and residual pesticidal compositions containing plant essential oils |
| US7537777B2 (en) | 1998-07-28 | 2009-05-26 | Ecosmart Technologies, Inc. | Synergistic and residual pesticidal compositions containing plant essential oils |
| JP2008514596A (en) * | 2004-09-24 | 2008-05-08 | ミシガン ステイト ユニバーシティー | Composition without carrier for the treatment of onychomycosis |
| US8920864B2 (en) | 2005-08-12 | 2014-12-30 | Takasago International Corporation | Sensation masking composition |
| US9974740B2 (en) | 2005-08-12 | 2018-05-22 | Takasago International Corporation (Usa) | Sensation masking composition |
| CN103301268A (en) * | 2013-06-13 | 2013-09-18 | 中国人民解放军海军总医院 | Ointment for jellyfish sting and preparation method thereof |
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