JPH0390032A - Production of mugwort leaf extract - Google Patents
Production of mugwort leaf extractInfo
- Publication number
- JPH0390032A JPH0390032A JP1226329A JP22632989A JPH0390032A JP H0390032 A JPH0390032 A JP H0390032A JP 1226329 A JP1226329 A JP 1226329A JP 22632989 A JP22632989 A JP 22632989A JP H0390032 A JPH0390032 A JP H0390032A
- Authority
- JP
- Japan
- Prior art keywords
- extract
- mugwort
- leaves
- ultrafiltration
- liquid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000004519 manufacturing process Methods 0.000 title claims description 4
- 240000006891 Artemisia vulgaris Species 0.000 title abstract description 7
- 235000003261 Artemisia vulgaris Nutrition 0.000 title abstract description 7
- 239000007788 liquid Substances 0.000 claims abstract description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 12
- 238000000108 ultra-filtration Methods 0.000 claims abstract description 10
- 238000009835 boiling Methods 0.000 claims description 3
- 208000003251 Pruritus Diseases 0.000 abstract description 4
- 239000000706 filtrate Substances 0.000 abstract description 4
- 238000001914 filtration Methods 0.000 abstract description 4
- 239000002244 precipitate Substances 0.000 abstract description 3
- 208000020832 chronic kidney disease Diseases 0.000 abstract description 2
- 208000022831 chronic renal failure syndrome Diseases 0.000 abstract description 2
- 230000000857 drug effect Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000001747 exhibiting effect Effects 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 description 5
- 238000000605 extraction Methods 0.000 description 3
- 239000008213 purified water Substances 0.000 description 3
- 235000015701 Artemisia arbuscula Nutrition 0.000 description 2
- 235000002657 Artemisia tridentata Nutrition 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- 239000012141 concentrate Substances 0.000 description 2
- 230000007803 itching Effects 0.000 description 2
- 230000007721 medicinal effect Effects 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- 235000004356 Artemisia montana Nutrition 0.000 description 1
- 241000638253 Artemisia montana Species 0.000 description 1
- 235000017519 Artemisia princeps Nutrition 0.000 description 1
- 244000065027 Artemisia princeps Species 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000012466 permeate Substances 0.000 description 1
- 108010040933 progressin Proteins 0.000 description 1
- 239000013049 sediment Substances 0.000 description 1
- 238000010186 staining Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
Description
【発明の詳細な説明】 ［産業上の利用分野］ 本発明は、艾葉エキスの製法に関する。[Detailed description of the invention] [Industrial application field] TECHNICAL FIELD The present invention relates to a method for producing Molecularis leaf extract.
［従来の技術］
艾葉（ヨモギ、Ａｒｔｅｍｉｓｉａ ｐｒｉｎｃｅｐｓ
Ｐａｍｐａｎｉｎｉ又はヤマヨモギ、Ａｒｔｅｍｉｓ
ｉａ ｍｏｎｔａｎａ Ｐａｍｐａｎｉｎｉ ）は、古
来から種々の薬効があることが知られているが、最近に
なりその葉及び枝先の熱湯抽出液は皮膚そう痒症特に慢
性腎相不全患者のそれに対して著効があるとされる［中
塩哲士ら、Ｐｒｏｇｒｅｓｓｉｎ Ｍｅｄｉｃｉｎｅ、
９．１２５９〜１２６３ （１９８９）参照］。[Prior art] Artemisia princeps
Pampanini or sagebrush, Artemis
Ia montana Pampanini) has been known to have various medicinal properties since ancient times, but recently a hot water extract of its leaves and branch tips has been shown to be effective against skin itching, especially in patients with chronic renal phase failure. It is said that there is [Tetsushi Nakashio et al., Progressin Medicine,
9.1259-1263 (1989)].
しかし、この熱湯抽出液は、黒色に近い濃褐色を呈し、
使用に当たって、例えば液を含ませた布或いはガーゼ又
は患者の衣服に色を付けたりなどの不都合が生じ易い。However, this hot water extract has a dark brown color that is almost black.
During use, inconveniences may occur, such as staining the cloth or gauze soaked with the liquid or the patient's clothing.
本発明者は、薬効を損なうことなくこのような欠点を除
くため、種々検討した結果、本発明を見い出した。The present inventor has conducted various studies in order to eliminate such drawbacks without impairing the medicinal efficacy, and as a result, has discovered the present invention.
［発明の概要コ
本発明は、交葉の葉及び枝先を熱湯で抽出し、得られた
液を限外濾過により処理する艾葉エキスの製法に関する
。[Summary of the Invention] The present invention relates to a method for producing a coccyx leaf extract, which involves extracting the leaves and branch tips of a coccyx with boiling water and treating the resulting liquid by ultrafiltration.
本発明を行なうには、先ず艾葉（ヨモギ、Ａ「ｔｅｍｉ
ｓｌａ ｐｒｉｎｃｅｐｓ Ｐａｍｐａｎｉｎｉ又はヤ
マヨモギ、Ａｒｔｅｍｉｓｉａ ｍｏｎｔａｎａ Ｐａ
ｍｐａｎｉｎｉ ）の葉及び枝先を熱湯で抽出する。抽
出には、乾燥交葉１ｋｇ当たり５〜６０ｆｆｉ好ましく
は１０〜４０ｇ、最も好ましくは１５〜３０Ｑ、の水を
用いる。加熱は、約９０〜１００℃で行なう、加熱時間
は、例えば１０分以上好ましくは１５〜３０分である。To carry out the present invention, first, A. temi
sla princeps Pampanini or sagebrush, Artemisia montana Pa
mpanini) leaves and branch tips are extracted with boiling water. For the extraction, 5 to 60 ffi, preferably 10 to 40 g, most preferably 15 to 30 Q, of water are used per kg of dried leaves. Heating is performed at about 90 to 100° C., and the heating time is, for example, 10 minutes or more, preferably 15 to 30 minutes.
加熱処理後、抽出物を濾過して濾液を得る。After the heat treatment, the extract is filtered to obtain a filtrate.
次に、得られた液を限外濾過により処理する。The resulting liquid is then treated by ultrafiltration.
この場合、処理前に、液を数日間冷蔵し、生じた沈殿を
濾過などにより除くのが好ましい。限外濾過では、分子
量約５０００以上好ましくは約７゜ＯＯ以上最も好まし
くは約１００００以上の分ｄを除くようにする。このよ
うにすることにより、限外濾過後の液の薬効を滅するこ
とがない。しがも限外濾過後の液の色は、その処理前の
液のそれに比べて非常に薄くなり、ガーゼや衣服を汚す
ことが殆どない。In this case, it is preferable to refrigerate the liquid for several days before treatment and remove the resulting precipitate by filtration or the like. In the ultrafiltration, fractions d having a molecular weight of about 5,000 or more, preferably about 7°OO or more, and most preferably about 10,000 or more are removed. By doing so, the medicinal efficacy of the liquid after ultrafiltration is not lost. However, the color of the liquid after ultrafiltration is much lighter than that of the liquid before treatment, and it hardly stains gauze or clothes.
又、限外濾過を行なうことにより、加熱抽出後の操作に
より混入する雑菌も完全に除去されることになる。In addition, by performing ultrafiltration, any bacteria that may be introduced during the operation after heating and extraction will be completely removed.
［実施例］
実施例 １
精製水５０党を沸騰させ、これに艾葉２．’５’ｋｇを
加え、２０分間加熱を続け、抽出した。得られた抽出物
を濾過し、濾液を得た。一方、濾過残渣を精製水を用い
て洗浄し、得られた洗浄液と先の濾液とを合わせ５０ｇ
、の抽出液を得た。[Example] Example 1 Boil 50 parts of purified water and add 2. 5 kg was added, heating was continued for 20 minutes, and extraction was performed. The obtained extract was filtered to obtain a filtrate. On the other hand, wash the filtration residue using purified water, and combine the obtained washing liquid and the previous filtrate to 50 g.
An extract of , was obtained.
抽出液を２〜３日冷蔵し、生じた澱及び沈殿を濾過して
除き、次に分画分子量１００００の限外濾過膜を使用し
て濃縮した。得られた濃縮液に精製水を加えてさらに濃
縮した。この操作により、限外濾過膜透過液５０息を得
た。The extract was refrigerated for 2 to 3 days, the resulting lees and precipitates were removed by filtration, and then concentrated using an ultrafiltration membrane with a molecular weight cutoff of 10,000. Purified water was added to the obtained concentrate to further concentrate it. Through this operation, 50 volumes of ultrafiltration membrane permeate were obtained.
得られた液は、澱や濁りが全くなく、透明でしかもうす
い茶色を呈した。そして、かゆみを訴える慢性腎不全患
者の清拭又はバッティングに用いても非常に有効であっ
た。The resulting liquid was completely free of sediment and turbidity, and was transparent and pale brown in color. It was also very effective when used for cleaning or swabbing patients with chronic renal failure who complained of itching.
一方、熱湯抽出液の色を除くために、脱色法として一般
に用いられている活性炭を使用すると、色は殆ど除かれ
るが、薬効を期待することができなかった。On the other hand, when activated carbon, which is commonly used as a decolorizing method, is used to remove the color of the hot water extract, most of the color is removed, but no medicinal effects could be expected.
Claims (1)
過により処理する艾葉エキスの製法。A method for producing Molecular leaf extract, which involves extracting the leaves and branch tips of Molecular leaf with boiling water and treating the resulting liquid with ultrafiltration.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1226329A JPH0390032A (en) | 1989-08-31 | 1989-08-31 | Production of mugwort leaf extract |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1226329A JPH0390032A (en) | 1989-08-31 | 1989-08-31 | Production of mugwort leaf extract |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH0390032A true JPH0390032A (en) | 1991-04-16 |
Family
ID=16843469
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP1226329A Pending JPH0390032A (en) | 1989-08-31 | 1989-08-31 | Production of mugwort leaf extract |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH0390032A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103933206A (en) * | 2014-04-20 | 2014-07-23 | 文成县刀锋科技有限公司 | Medicament lotion for treating skin itch of old people |
-
1989
- 1989-08-31 JP JP1226329A patent/JPH0390032A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103933206A (en) * | 2014-04-20 | 2014-07-23 | 文成县刀锋科技有限公司 | Medicament lotion for treating skin itch of old people |
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