JPH0140005B2 - - Google Patents

Info

Publication number: JPH0140005B2
Authority: JP; Japan
Prior art keywords: caries; hinokitiol; mixture; myutans; activity
Prior art date: 1983-03-26
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

JP58051199A

Other languages

English (en)

Japanese (ja)

Other versions

JPS59175410A (ja

Inventor

Keiji Iguchi

Masayoshi Fukuda

Koichi Ogata

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Kracie Foods Ltd

Original Assignee

Kanebo Foods Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-03-26

Filing date

1983-03-26

Publication date

1989-08-24

1983-03-26 Application filed by Kanebo Foods Ltd filed Critical Kanebo Foods Ltd

1983-03-26 Priority to JP58051199A priority Critical patent/JPS59175410A/ja

1984-10-04 Publication of JPS59175410A publication Critical patent/JPS59175410A/ja

1989-08-24 Publication of JPH0140005B2 publication Critical patent/JPH0140005B2/ja

Status Granted legal-status Critical Current

Links

FUWUEFKEXZQKKA-UHFFFAOYSA-N beta-thujaplicin Chemical compound CC(C)C=1C=CC=C(O)C(=O)C=1 FUWUEFKEXZQKKA-UHFFFAOYSA-N 0.000 claims description 32
239000000203 mixture Substances 0.000 claims description 28
TUFYVOCKVJOUIR-UHFFFAOYSA-N alpha-Thujaplicin Natural products CC(C)C=1C=CC=CC(=O)C=1O TUFYVOCKVJOUIR-UHFFFAOYSA-N 0.000 claims description 16
229930007845 β-thujaplicin Natural products 0.000 claims description 16
230000000675 anti-caries Effects 0.000 claims description 12
239000004480 active ingredient Substances 0.000 claims description 10
150000002596 lactones Chemical class 0.000 claims description 7
150000001732 carboxylic acid derivatives Chemical class 0.000 claims description 4
230000000694 effects Effects 0.000 description 26
208000002925 dental caries Diseases 0.000 description 23
241000894006 Bacteria Species 0.000 description 15
239000000243 solution Substances 0.000 description 13
239000000341 volatile oil Substances 0.000 description 12
CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 11
229930006000 Sucrose Natural products 0.000 description 11
230000002401 inhibitory effect Effects 0.000 description 11
239000005720 sucrose Substances 0.000 description 11
229920001503 Glucan Polymers 0.000 description 9
230000000844 anti-bacterial effect Effects 0.000 description 8
238000000034 method Methods 0.000 description 6
238000012360 testing method Methods 0.000 description 6
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 5
230000015572 biosynthetic process Effects 0.000 description 5
150000001875 compounds Chemical class 0.000 description 5
230000007794 irritation Effects 0.000 description 5
239000002609 medium Substances 0.000 description 5
ULGZDMOVFRHVEP-RWJQBGPGSA-N Erythromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 ULGZDMOVFRHVEP-RWJQBGPGSA-N 0.000 description 4
244000248349 Citrus limon Species 0.000 description 3
235000005979 Citrus limon Nutrition 0.000 description 3
241000194017 Streptococcus Species 0.000 description 3
239000003242 anti bacterial agent Substances 0.000 description 3
150000001735 carboxylic acids Chemical class 0.000 description 3
239000000796 flavoring agent Substances 0.000 description 3
235000019634 flavors Nutrition 0.000 description 3
239000003205 fragrance Substances 0.000 description 3
241001579869 Phazaca mutans Species 0.000 description 2
241000736892 Thujopsis dolabrata Species 0.000 description 2
239000002253 acid Substances 0.000 description 2
230000001476 alcoholic effect Effects 0.000 description 2
229940088710 antibiotic agent Drugs 0.000 description 2
210000002421 cell wall Anatomy 0.000 description 2
229940112822 chewing gum Drugs 0.000 description 2
235000015218 chewing gum Nutrition 0.000 description 2
229960003276 erythromycin Drugs 0.000 description 2
239000004615 ingredient Substances 0.000 description 2
VVOAZFWZEDHOOU-UHFFFAOYSA-N magnolol Chemical compound OC1=CC=C(CC=C)C=C1C1=CC(CC=C)=CC=C1O VVOAZFWZEDHOOU-UHFFFAOYSA-N 0.000 description 2
231100000957 no side effect Toxicity 0.000 description 2
239000003921 oil Substances 0.000 description 2
230000002265 prevention Effects 0.000 description 2
230000003449 preventive effect Effects 0.000 description 2
238000011160 research Methods 0.000 description 2
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
208000002064 Dental Plaque Diseases 0.000 description 1
102000004190 Enzymes Human genes 0.000 description 1
108090000790 Enzymes Proteins 0.000 description 1
229930182555 Penicillin Natural products 0.000 description 1
JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 description 1
241000194019 Streptococcus mutans Species 0.000 description 1
241000194023 Streptococcus sanguinis Species 0.000 description 1
238000002835 absorbance Methods 0.000 description 1
230000001580 bacterial effect Effects 0.000 description 1
239000003899 bactericide agent Substances 0.000 description 1
230000003115 biocidal effect Effects 0.000 description 1
230000001013 cariogenic effect Effects 0.000 description 1
239000004075 cariostatic agent Substances 0.000 description 1
238000004140 cleaning Methods 0.000 description 1
238000012258 culturing Methods 0.000 description 1
239000010639 cypress oil Substances 0.000 description 1
230000001747 exhibiting effect Effects 0.000 description 1
238000002474 experimental method Methods 0.000 description 1
238000000855 fermentation Methods 0.000 description 1
230000004151 fermentation Effects 0.000 description 1
235000013305 food Nutrition 0.000 description 1
235000003599 food sweetener Nutrition 0.000 description 1
239000001963 growth medium Substances 0.000 description 1
208000015181 infectious disease Diseases 0.000 description 1
238000001802 infusion Methods 0.000 description 1
230000000968 intestinal effect Effects 0.000 description 1
230000007774 longterm Effects 0.000 description 1
230000002101 lytic effect Effects 0.000 description 1
238000004519 manufacturing process Methods 0.000 description 1
235000012054 meals Nutrition 0.000 description 1
238000000691 measurement method Methods 0.000 description 1
238000002156 mixing Methods 0.000 description 1
239000002324 mouth wash Substances 0.000 description 1
239000005445 natural material Substances 0.000 description 1
229940049954 penicillin Drugs 0.000 description 1
238000000053 physical method Methods 0.000 description 1
230000002250 progressing effect Effects 0.000 description 1
239000012064 sodium phosphate buffer Substances 0.000 description 1
238000003756 stirring Methods 0.000 description 1
239000003765 sweetening agent Substances 0.000 description 1
230000002195 synergetic effect Effects 0.000 description 1
230000008685 targeting Effects 0.000 description 1
229940034610 toothpaste Drugs 0.000 description 1
239000000606 toothpaste Substances 0.000 description 1
-1 troches Substances 0.000 description 1
238000002604 ultrasonography Methods 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Birds (AREA)
Oil, Petroleum & Natural Gas (AREA)
Epidemiology (AREA)
Chemical & Material Sciences (AREA)
Oral & Maxillofacial Surgery (AREA)
Medicines Containing Plant Substances (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Cosmetics (AREA)

JP58051199A 1983-03-26 1983-03-26 抗齲蝕性組成物 Granted JPS59175410A (ja)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
JP58051199A JPS59175410A (ja)	1983-03-26	1983-03-26	抗齲蝕性組成物

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP58051199A JPS59175410A (ja)	1983-03-26	1983-03-26	抗齲蝕性組成物

Publications (2)

Publication Number	Publication Date
JPS59175410A JPS59175410A (ja)	1984-10-04
JPH0140005B2 true JPH0140005B2 (xx)	1989-08-24

Family

ID=12880217

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP58051199A Granted JPS59175410A (ja)	1983-03-26	1983-03-26	抗齲蝕性組成物

Country Status (1)

Country	Link
JP (1)	JPS59175410A (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH0772124B2 (ja) *	1986-02-27	1995-08-02	ライオン株式会社	口腔用組成物
JPH0816049B2 (ja) *	1986-09-09	1996-02-21	ライオン株式会社	タバコヤニ消臭用口腔用組成物
JPH03167114A (ja) *	1989-11-24	1991-07-19	Mikimoto Seiyaku Kk	口腔用組成物
JP2582736B2 (ja) *	1990-05-15	1997-02-19	鐘紡株式会社	歯周病菌の増殖抑制剤
JPH04346933A (ja) *	1991-05-24	1992-12-02	Pokka Corp	虫歯菌、歯周病原菌増殖阻害剤
US5560912A (en) *	1994-06-27	1996-10-01	Technion Research & Development Foundation Ltd.	Method for inhibiting growth of helicobacter pylori
ES2187560T3 (es) *	1994-07-25	2003-06-16	Warner Lambert Co	Dentifrico antiseptico.
US6042812A (en) *	1996-11-26	2000-03-28	The Procter & Gamble Company	Flavor systems for oral care products
US5939050A (en) *	1997-04-04	1999-08-17	Optiva Corp.	Antimicrobial compositions
AU6877398A (en) *	1997-04-04	1998-10-30	Optiva Corp.	Antimicrobial agents for oral hygiene products
US6248309B1 (en)	1997-04-04	2001-06-19	Optiva Corporation	Gums containing antimicrobial agents
US6689342B1 (en)	2002-07-29	2004-02-10	Warner-Lambert Company	Oral care compositions comprising tropolone compounds and essential oils and methods of using the same
US6787675B2 (en)	2002-07-29	2004-09-07	Warner-Lambert Company	Substituted tropolone compounds, oral care compositions containing the same and methods of using the same
EP1536759A1 (en) *	2002-07-29	2005-06-08	Warner-Lambert Company LLC	Oral care composition comprising tropolone compounds and essential oils
US7297327B2 (en) *	2004-12-21	2007-11-20	Colgate-Palmolive Company	Oral care malodor composition
JP2020183350A (ja) *	2019-04-29	2020-11-12	株式会社ビィ・ソニック	歯磨剤
EP4359085A2 (en) *	2021-06-24	2024-05-01	Firmenich SA	Oral care compositions

Citations (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS503378A (xx) *	1973-05-11	1975-01-14
US4159315A (en) *	1977-11-28	1979-06-26	General Mills, Inc.	Plaque inhibiting composition and method
JPS54129136A (en) *	1978-03-30	1979-10-06	Yamanouchi Pharmaceut Co Ltd	Anti-dental plaque agent
JPS55120509A (en) *	1979-03-08	1980-09-17	Sunstar Inc	Oral cavity agent composition blended with crude drug
JPS5929618A (ja) *	1982-08-11	1984-02-16	T Hasegawa Co Ltd	虫歯防止剤
JPS5929619A (ja) *	1982-08-11	1984-02-16	T Hasegawa Co Ltd	虫歯防止剤

1983
- 1983-03-26 JP JP58051199A patent/JPS59175410A/ja active Granted

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS503378A (xx) *	1973-05-11	1975-01-14
US4159315A (en) *	1977-11-28	1979-06-26	General Mills, Inc.	Plaque inhibiting composition and method
JPS54129136A (en) *	1978-03-30	1979-10-06	Yamanouchi Pharmaceut Co Ltd	Anti-dental plaque agent
JPS55120509A (en) *	1979-03-08	1980-09-17	Sunstar Inc	Oral cavity agent composition blended with crude drug
JPS5929618A (ja) *	1982-08-11	1984-02-16	T Hasegawa Co Ltd	虫歯防止剤
JPS5929619A (ja) *	1982-08-11	1984-02-16	T Hasegawa Co Ltd	虫歯防止剤

Also Published As

Publication number	Publication date
JPS59175410A (ja)	1984-10-04

Publication	Publication Date	Title
JPH0140005B2 (xx)	1989-08-24
JP3877537B2 (ja)	2007-02-07	口腔用組成物用抗菌剤およびそれを含む口腔用組成物
EP0666731B1 (en)	2004-09-15	Antibacterial mouthwash
US20090252690A1 (en)	2009-10-08	Flavoured Mouth Wash Composition
JP3969272B2 (ja)	2007-09-05	抗う蝕、抗歯周病用組成物
EP0256566A1 (en)	1988-02-24	Use of usnic acid or derivatives thereof in the treatment of dental caries
JP2006124384A (ja)	2006-05-18	口腔用組成物
JP3614479B2 (ja)	2005-01-26	歯周病原因菌又はう蝕原因菌抑制剤及びこれらを含有する口腔用組成物及び食品
JPS63277612A (ja)	1988-11-15	口腔用組成物
JPH0234322B2 (xx)	1990-08-02
JPS647964B2 (xx)	1989-02-10
JPH03240721A (ja)	1991-10-28	口腔用組成物
JPH0432047B2 (xx)	1992-05-28
JPH0225413A (ja)	1990-01-26	う蝕予防剤の製造方法
JP3009531B2 (ja)	2000-02-14	歯周病予防剤
JPH0639375B2 (ja)	1994-05-25	抗齲蝕剤
JP2738092B2 (ja)	1998-04-08	口腔用組成物
JPS5835484B2 (ja)	1983-08-03	口腔組成物
KR20020082308A (ko)	2002-10-31	귀전우 추출물을 함유하는 구강용 조성물
JPS6258324B2 (xx)	1987-12-05
KR20100003411A (ko)	2010-01-11	택사추출물을 함유하는 충치억제용 조성물
JPH0567608B2 (xx)	1993-09-27
JPS5812251B2 (ja)	1983-03-07	口腔用組成物
JPH07215830A (ja)	1995-08-15	口腔用組成物
JPH0320364B2 (xx)	1991-03-19