JP7482872B2 - 速度変化を使用したlvad患者の高血圧の検出 - Google Patents
速度変化を使用したlvad患者の高血圧の検出 Download PDFInfo
- Publication number
- JP7482872B2 JP7482872B2 JP2021532019A JP2021532019A JP7482872B2 JP 7482872 B2 JP7482872 B2 JP 7482872B2 JP 2021532019 A JP2021532019 A JP 2021532019A JP 2021532019 A JP2021532019 A JP 2021532019A JP 7482872 B2 JP7482872 B2 JP 7482872B2
- Authority
- JP
- Japan
- Prior art keywords
- pump
- period
- during
- pulsatility
- current
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 206010020772 Hypertension Diseases 0.000 title claims description 36
- 238000001514 detection method Methods 0.000 title claims description 4
- 239000008280 blood Substances 0.000 claims description 46
- 210000004369 blood Anatomy 0.000 claims description 46
- 238000000034 method Methods 0.000 claims description 23
- 230000007423 decrease Effects 0.000 claims description 15
- 230000002861 ventricular Effects 0.000 claims description 12
- 238000012545 processing Methods 0.000 claims description 8
- 238000004891 communication Methods 0.000 claims description 3
- 230000003247 decreasing effect Effects 0.000 claims description 3
- 230000000737 periodic effect Effects 0.000 claims description 3
- 230000010349 pulsation Effects 0.000 claims 4
- 230000000747 cardiac effect Effects 0.000 description 13
- 230000036772 blood pressure Effects 0.000 description 7
- 238000011144 upstream manufacturing Methods 0.000 description 7
- 238000005516 engineering process Methods 0.000 description 5
- 239000012530 fluid Substances 0.000 description 4
- 230000008901 benefit Effects 0.000 description 3
- 230000005294 ferromagnetic effect Effects 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 230000002411 adverse Effects 0.000 description 2
- 230000005291 magnetic effect Effects 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- AMBXMKTXDPOXAX-UHFFFAOYSA-N 2-[6-(2-hydroxyethyl)-3a,6-dimethyl-3-(6-methylheptan-2-yl)-2,3,4,5,5a,7,8,9,9a,9b-decahydro-1h-cyclopenta[a]naphthalen-7-yl]propan-1-ol Chemical compound C1CC(C(C)CO)C(C)(CCO)C2CCC3(C)C(C(C)CCCC(C)C)CCC3C21 AMBXMKTXDPOXAX-UHFFFAOYSA-N 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 238000003491 array Methods 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000013500 data storage Methods 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000001631 hypertensive effect Effects 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/02108—Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics
- A61B5/02116—Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics of pulse wave amplitude
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/686—Permanently implanted devices, e.g. pacemakers, other stimulators, biochips
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/50—Details relating to control
- A61M60/592—Communication of patient or blood pump data to distant operators for treatment purposes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
- A61B5/026—Measuring blood flow
- A61B5/029—Measuring or recording blood output from the heart, e.g. minute volume
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7271—Specific aspects of physiological measurement analysis
- A61B5/7282—Event detection, e.g. detecting unique waveforms indicative of a medical condition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/74—Details of notification to user or communication with user or patient ; user input means
- A61B5/746—Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/10—Location thereof with respect to the patient's body
- A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
- A61M60/126—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
- A61M60/148—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/10—Location thereof with respect to the patient's body
- A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
- A61M60/165—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable in, on, or around the heart
- A61M60/178—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable in, on, or around the heart drawing blood from a ventricle and returning the blood to the arterial system via a cannula external to the ventricle, e.g. left or right ventricular assist devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/20—Type thereof
- A61M60/205—Non-positive displacement blood pumps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/20—Type thereof
- A61M60/205—Non-positive displacement blood pumps
- A61M60/216—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
- A61M60/226—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly radial components
- A61M60/232—Centrifugal pumps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/20—Type thereof
- A61M60/205—Non-positive displacement blood pumps
- A61M60/216—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
- A61M60/237—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/20—Type thereof
- A61M60/205—Non-positive displacement blood pumps
- A61M60/216—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
- A61M60/237—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps
- A61M60/242—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps with the outlet substantially perpendicular to the axis of rotation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/40—Details relating to driving
- A61M60/403—Details relating to driving for non-positive displacement blood pumps
- A61M60/422—Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being electromagnetic, e.g. using canned motor pumps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/50—Details relating to control
- A61M60/508—Electronic control means, e.g. for feedback regulation
- A61M60/515—Regulation using real-time patient data
- A61M60/523—Regulation using real-time patient data using blood flow data, e.g. from blood flow transducers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/50—Details relating to control
- A61M60/508—Electronic control means, e.g. for feedback regulation
- A61M60/515—Regulation using real-time patient data
- A61M60/531—Regulation using real-time patient data using blood pressure data, e.g. from blood pressure sensors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/50—Details relating to control
- A61M60/508—Electronic control means, e.g. for feedback regulation
- A61M60/538—Regulation using real-time blood pump operational parameter data, e.g. motor current
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/50—Details relating to control
- A61M60/508—Electronic control means, e.g. for feedback regulation
- A61M60/562—Electronic control means, e.g. for feedback regulation for making blood flow pulsatile in blood pumps that do not intrinsically create pulsatile flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
- A61M60/50—Details relating to control
- A61M60/585—User interfaces
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/18—General characteristics of the apparatus with alarm
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
- A61M2205/3334—Measuring or controlling the flow rate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
- A61M2205/3344—Measuring or controlling pressure at the body treatment site
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3365—Rotational speed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
- A61M2206/11—Laminar flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
- A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/12—Blood circulatory system
- A61M2210/125—Heart
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/04—Heartbeat characteristics, e.g. ECG, blood pressure modulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2230/00—Measuring parameters of the user
- A61M2230/30—Blood pressure
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Mechanical Engineering (AREA)
- Medical Informatics (AREA)
- Surgery (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Physiology (AREA)
- Vascular Medicine (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Signal Processing (AREA)
- Psychiatry (AREA)
- Artificial Intelligence (AREA)
- Human Computer Interaction (AREA)
- External Artificial Organs (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
Description
Claims (15)
- 埋め込み型血液ポンプを含む、心室補助装置を有する患者に適用可能に構成された高血圧検出システムの作動方法であって、
前記高血圧検出システムは、コントローラを備え、
前記コントローラは、
第1の期間中に第1のポンプ設定速度で前記埋め込み型血液ポンプを動作させることと、
前記第1の期間中、第1の流量脈動性および第1の電流脈動性からなる群からの少なくとも1つを測定することと、
前記第1の期間の後の第2の期間中に前記第1のポンプ設定速度を第2のポンプ設定速度に下げることと、
前記第2の期間中、第2の流量脈動性および第2の電流脈動性からなる群からの少なくとも1つを測定することと、
前記第1の期間中の前記第1のポンプ設定速度での前記第1の流量脈動性および前記第1の電流脈動性からなる群からの少なくとも1つと比較して、前記第2のポンプ設定速度での前記第2の期間中に前記第2の流量脈動性および前記第2の電流脈動性からなる群からの少なくとも1つが増加しているか否かを判定することと
を実行するように構成され、
前記第1の期間中に測定された脈動性と比較して前記第2の期間中に測定された前記脈動性が増加していることは、前記患者の高血圧に対応する、
方法。 - 前記コントローラは、
前記第1の期間中の前記第1のポンプ設定速度での前記第1の流量脈動性および前記第1の電流脈動性からなる群からの少なくとも1つと比較して、前記第2のポンプ設定速度での前記第2の期間中に前記第2の流量脈動性および前記第2の電流脈動性からなる群からの少なくとも1つが増加したと判定された場合、高血圧の存在を示すアラートを生成すること
をさらに実行する、
請求項1に記載の方法。 - 前記第2のポンプ設定速度は、前記第1のポンプ設定速度より少なくとも200rpm低い、
請求項1または2に記載の方法。 - 前記第2の期間は前記第1の期間よりも短い、
請求項1~3のうちいずれか1つに記載の方法。 - 前記埋め込み型血液ポンプの連続動作中、前記第1の期間および前記第2の期間は連続している、
請求項1~4のうちいずれか1つに記載の方法。 - 前記第1の期間および前記第2の期間は、所定の間隔で周期的である、
請求項5に記載の方法。 - 前記埋め込み型血液ポンプは遠心流血液ポンプである、
請求項1~5のうちいずれか1つに記載の方法。 - 前記埋め込み型血液ポンプは軸流血液ポンプである、
請求項1~5のうちいずれか1つに記載の方法。 - 前記コントローラは、
第1の流量脈動性および第2の流量脈動性を測定する、
請求項1に記載の方法。 - 前記コントローラは、
前記第1の電流脈動性および前記第2の電流脈動性を測定する、
請求項1に記載の方法。 - 心室補助装置を有する患者の高血圧を検出するためのシステムであって、前記心室補助装置が埋め込み型血液ポンプを含み、前記システムが、
前記埋め込み型血液ポンプと通信するコントローラであって、処理回路を含むプロセッサを有するコントローラを備え、
前記処理回路が、
前記埋め込み型血液ポンプを第1の期間中に第1のポンプ設定速度で動作させ、
前記第1の期間中、第1の流量の最小値および第1の電流の最小値からなる群からの少なくとも1つを測定し、
前記第1のポンプ設定速度を前記第1の期間の後の第2の期間中に第2のポンプ設定速度に下げ、
第2の期間中、第2の流量の最小値および第2の電流の最小値からなる群からの少なくとも1つを測定し、
前記第2の流量の最小値および前記第2の電流の最小値からなる群からの少なくとも1つが、前記第2のポンプ設定速度で第2の期間中に所定量を超えて減少する場合、
前記第2のポンプ設定速度を前記第1のポンプ設定速度に上げる、または
患者の高血圧を示すフラグまたはアラートを生成する
ように構成された、システム。 - 前記コントローラは、前記第2の流量の最小値および前記第2の電流の最小値からなる群からの前記少なくとも1つが、所定の量を超えて、前記第2のポンプ設定速度で前記第2の期間中に減少した場合に、高血圧の存在を示すアラートを生成するように構成される、
請求項11に記載のシステム。 - 前記第2のポンプ設定速度は、
前記第1のポンプ設定速度よりも少なくとも200rpm低い、
請求項11または12に記載のシステム。 - 前記第2の期間は、前記第1の期間よりも短い、
請求項11~13のうちいずれか1つに記載のシステム。 - 前記埋め込み型血液ポンプの連続動作中、前記第1の期間および前記第2の期間は連続している、
請求項11~14のうちいずれか1つに記載のシステム。
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962811625P | 2019-02-28 | 2019-02-28 | |
US62/811,625 | 2019-02-28 | ||
US16/775,982 US11666281B2 (en) | 2019-02-28 | 2020-01-29 | Detection of hypertension in LVAD patients using speed change |
US16/775,982 | 2020-01-29 | ||
PCT/US2020/017587 WO2020176242A1 (en) | 2019-02-28 | 2020-02-11 | Detection of hypertension in lvad patients using speed change |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2022522090A JP2022522090A (ja) | 2022-04-14 |
JP7482872B2 true JP7482872B2 (ja) | 2024-05-14 |
Family
ID=72236976
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2021532019A Active JP7482872B2 (ja) | 2019-02-28 | 2020-02-11 | 速度変化を使用したlvad患者の高血圧の検出 |
Country Status (6)
Country | Link |
---|---|
US (2) | US11666281B2 (ja) |
EP (1) | EP3930782A1 (ja) |
JP (1) | JP7482872B2 (ja) |
KR (1) | KR20210138561A (ja) |
CN (1) | CN113474038A (ja) |
WO (1) | WO2020176242A1 (ja) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11504520B2 (en) * | 2020-02-20 | 2022-11-22 | Medtronic, Inc. | Cost function for response algorithm |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20130046129A1 (en) | 2011-08-15 | 2013-02-21 | Terumo Kabushiki Kaisha | Non-Invasive Diagnostics for Ventrical Assist Device |
JP2013531528A (ja) | 2010-06-22 | 2013-08-08 | ソラテック コーポレーション | 流体送達システム及び流体送達システムを監視するための方法 |
US20150151032A1 (en) | 2012-06-06 | 2015-06-04 | Heartware, Inc. | Speed change algorithim for a continuous flow blood pump |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5840070A (en) | 1996-02-20 | 1998-11-24 | Kriton Medical, Inc. | Sealless rotary blood pump |
US6387037B1 (en) * | 1997-10-09 | 2002-05-14 | Orqis Medical Corporation | Implantable heart assist system and method of applying same |
CZ305727B6 (cs) | 2000-03-27 | 2016-02-24 | The Cleveland Clinic Foundation | Pomocný přístroj pro pacienty s onemocněním srdce a způsob řízení průtoku krve krevní pumpou |
US20050159639A1 (en) | 2002-05-15 | 2005-07-21 | Mikhail Skliar | Physiologically based control system and method for using the same |
AU2003903726A0 (en) * | 2003-07-18 | 2003-07-31 | Ventracor Limited | A device for detecting heart pumping state |
US8419609B2 (en) | 2005-10-05 | 2013-04-16 | Heartware Inc. | Impeller for a rotary ventricular assist device |
JP5155186B2 (ja) | 2006-01-13 | 2013-02-27 | ハートウェア、インコーポレイテッド | 回転式血液ポンプ |
EP1847281A1 (en) | 2006-04-20 | 2007-10-24 | Ventrassist Pty Ltd | System and method of controlling a rotary blood pump |
US7963905B2 (en) | 2006-10-11 | 2011-06-21 | Thoratec Corporation | Control system for a blood pump |
US8562507B2 (en) | 2009-02-27 | 2013-10-22 | Thoratec Corporation | Prevention of aortic valve fusion |
WO2012040544A1 (en) * | 2010-09-24 | 2012-03-29 | Thoratec Corporation | Control of circulatory assist systems |
EP2642947B1 (en) * | 2010-11-22 | 2019-05-22 | Aria CV, Inc. | System for reducing pulsatile pressure |
EP3033120B1 (en) | 2013-08-14 | 2017-10-04 | Heartware, Inc. | Impeller for axial flow pump |
AU2015268105B2 (en) | 2014-05-29 | 2019-12-12 | Heartware, Inc. | Ventricular assist device method and apparatus |
US20160166211A1 (en) * | 2014-12-02 | 2016-06-16 | Heartware, Inc. | Mean arterial pressure estimation |
US11235139B2 (en) * | 2018-05-17 | 2022-02-01 | Heartware, Inc. | Current-speed relationship for instantaneous suction detection algorithm in LVADS |
-
2020
- 2020-01-29 US US16/775,982 patent/US11666281B2/en active Active
- 2020-02-11 EP EP20709985.4A patent/EP3930782A1/en active Pending
- 2020-02-11 JP JP2021532019A patent/JP7482872B2/ja active Active
- 2020-02-11 WO PCT/US2020/017587 patent/WO2020176242A1/en unknown
- 2020-02-11 CN CN202080016660.2A patent/CN113474038A/zh active Pending
- 2020-02-11 KR KR1020217019256A patent/KR20210138561A/ko unknown
-
2023
- 2023-05-15 US US18/317,823 patent/US20230277136A1/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2013531528A (ja) | 2010-06-22 | 2013-08-08 | ソラテック コーポレーション | 流体送達システム及び流体送達システムを監視するための方法 |
US20130046129A1 (en) | 2011-08-15 | 2013-02-21 | Terumo Kabushiki Kaisha | Non-Invasive Diagnostics for Ventrical Assist Device |
US20150151032A1 (en) | 2012-06-06 | 2015-06-04 | Heartware, Inc. | Speed change algorithim for a continuous flow blood pump |
Also Published As
Publication number | Publication date |
---|---|
KR20210138561A (ko) | 2021-11-19 |
WO2020176242A1 (en) | 2020-09-03 |
CN113474038A (zh) | 2021-10-01 |
US20230277136A1 (en) | 2023-09-07 |
EP3930782A1 (en) | 2022-01-05 |
US20200275890A1 (en) | 2020-09-03 |
JP2022522090A (ja) | 2022-04-14 |
US11666281B2 (en) | 2023-06-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US11872384B2 (en) | Method of operating a blood pump having a magnetically levitated impeller | |
CN111655307B (zh) | 具有叶轮冲洗操作的轴向血泵 | |
CN109562213B (zh) | 抽吸检测方法和设备 | |
EP3131595B1 (en) | Systems for lvad operation during communication losses | |
EP3790606B1 (en) | Axial pump pressure algorithm with field oriented control | |
EP3185924A1 (en) | Blood pump and method of suction detection | |
WO2016033133A1 (en) | Blood pump and method of suction detection | |
JP2003210572A (ja) | 遠心式液体ポンプ装置 | |
WO2019112825A1 (en) | Blood pump with impeller rinse operation | |
US20230277136A1 (en) | Detection of hypertension in lvad patients using speed change | |
WO2021101822A1 (en) | Method to extract and quantify the cardiac end diastolic point/mitral valve closing point from the hvad estimated flow waveform | |
US11982295B2 (en) | Pumping device for pumping liquids, comprising a centrifugal pump with a radially pumping pump wheel with a hollow center | |
JP4251732B2 (ja) | 血液ポンプ |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20230208 |
|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20231208 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20231212 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20240226 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20240328 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20240430 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 7482872 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |