JP7443462B2 - 治療計画画像、断片内3d画像、及び断片内2dx線画像の画像見当合わせ - Google Patents
治療計画画像、断片内3d画像、及び断片内2dx線画像の画像見当合わせ Download PDFInfo
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Description
この出願は、これにより引用によってその内容全体が組み込まれる2017年1月6日出願の米国仮特許出願第62/443,581号の利益を主張する2018年1月4日出願の米国特許出願第15/862,438号の利益を主張するものである。
302 基準画像
304 動作画像
306 見当合わせ
309 強調基準画像
Claims (21)
- メモリと、
治療計画画像を含む患者の基準画像と該患者の断片内画像の間での変換を決定する第1の画像見当合わせを行い、該基準画像及び該断片内画像が該患者のターゲット位置を含む3次元(3D)画像であり、
前記患者の前記基準画像に対する第1のデジタル再構成放射線写真(DRR)を通じて該患者の該基準画像と2次元(2D)断片内X線画像の間での変換を決定する第2の画像見当合わせを行い、かつ
前記患者の治療中に、前記第1の画像見当合わせ及び前記第2の画像見当合わせに基づいて一定期間にわたって前記ターゲット位置で少なくとも並進変化を追跡する、
ように前記メモリと作動的に結合された処理デバイスと、
を含むことを特徴とするシステム。 - 前記基準画像は、キロボルトコンピュータ断層映像(kV-CT)画像、磁気共鳴撮像(MRI)画像、キロボルト円錐ビームコンピュータ断層映像(kV-CBCT)画像、又はメガボルトコンピュータ断層映像(MVCT)画像のうちの1つであることを特徴とする請求項1に記載のシステム。
- 前記断片内画像は、キロボルト円錐ビームコンピュータ断層映像(kV-CBCT)画像、メガボルト円錐ビームコンピュータ断層映像(MV-CBCT)画像、メガボルトコンピュータ断層映像(MVCT)画像、又はヘリカルkV-CT画像のうちの1つであることを特徴とする請求項1に記載のシステム。
- 処理デバイスによって実行された時に、
処理デバイスにより、治療計画画像を含む患者の基準画像と該患者の断片内画像の間での変換を決定する第1の画像見当合わせを行い、該基準画像及び該断片内画像が該患者のターゲット位置を含んでおり、
前記処理デバイスにより、前記患者の前記基準画像に対する第1のデジタル再構成放射線写真(DRR)を通じて該患者の該基準画像と2次元(2D)断片内X線画像の間での変換を決定する第2の画像見当合わせを行い、かつ
前記患者の治療中に、前記第1の画像見当合わせ及び前記第2の画像見当合わせに基づいて一定期間にわたって前記ターゲット位置で少なくとも並進変化を追跡する、
ことを前記処理デバイスに行わせる命令、
を含むことを特徴とする非一時的コンピュータ可読媒体。 - 前記処理デバイスは、更に、
前記断片内画像に対する第2のDRRを発生し、
前記第2のDRRを通じて前記断片内画像と前記断片内X線画像の間での変換を決定する第3の画像見当合わせを行い、かつ
前記患者の治療中に、前記第3の見当合わせに基づいて一定期間にわたって前記ターゲット位置で少なくとも前記並進変化を追跡する、
ことを特徴とする請求項4に記載の非一時的コンピュータ可読媒体。 - 前記基準画像、前記断片内画像、及び前記断片内X線画像は、ヘリカル放射線送出システムの撮像ソースによって又は前記患者に対する異なる位置での1又は2以上の撮像ソースによって発生されることを特徴とする請求項4に記載の非一時的コンピュータ可読媒体。
- 前記処理デバイスは、更に、
前記第1のDRRに基づいて前記患者に関連付けられた基準配置の変化を検出し、かつ
前記基準配置の変化に対処するために前記患者の治療送出に関連付けられた追跡アルゴリズムを修正する、
ことを特徴とする請求項4に記載の非一時的コンピュータ可読媒体。 - 患者のターゲット位置を追跡するシステムの処理デバイスの作動方法において、
前記処理デバイスが、治療計画画像を含む患者の基準画像と該患者の断片内画像の間での変換を決定する第1の画像見当合わせを行い、該基準画像及び該断片内画像が該患者のターゲット位置を含む3次元(3D)画像であり、
前記処理デバイスが、前記断片内画像に対する第1のデジタル再構成放射線写真(DRR)を通じて前記患者の該断片内画像と2次元(2D)断片内X線画像の間での変換を決定する第2の画像見当合わせを行い、
前記処理デバイスが、前記患者の治療中に、前記第1の画像見当合わせ及び前記第2の画像見当合わせに基づいて一定期間にわたって前記ターゲット位置で少なくとも並進変化を追跡する、
ことを特徴とする作動方法。 - 前記断片内画像は、前記基準画像よりも高い空間解像度を有することを特徴とする請求項8に記載の作動方法。
- 前記基準画像は、キロボルトコンピュータ断層映像(kV-CT)画像、磁気共鳴撮像(MRI)画像、キロボルト円錐ビームコンピュータ断層映像(kV-CBCT)画像、又はメガボルトコンピュータ断層映像(MVCT)画像のうちの1つであることを特徴とする請求項8に記載の作動方法。
- 前記断片内画像は、キロボルト円錐ビームコンピュータ断層映像(kV-CBCT)画像、メガボルト円錐ビームコンピュータ断層映像(MV-CBCT)画像、メガボルトコンピュータ断層映像(MVCT)画像、又はヘリカルkV-CT画像のうちの1つであることを特徴とする請求項8に記載の作動方法。
- 前記第1のDRRは、毎日の患者姿勢及び変形に対応することを特徴とする請求項8に記載の作動方法。
- 前記処理デバイスが、更に、
前記第1のDRRに基づいて前記患者に関連付けられた基準配置の変化を検出し、
前記基準配置の変化に対処するために前記患者の治療送出に関連付けられた追跡アルゴリズムを修正する、
ことを特徴とする請求項8に記載の作動方法。 - 前記処理デバイスが、更に、
前記患者の強調された基準画像と前記断片内X線画像の間での変換を該強調基準画像の第2のDRRを通じて決定する第3の画像見当合わせを行い、
前記患者の治療中に、前記第3の見当合わせに基づいて一定期間にわたって前記ターゲット位置で少なくとも前記並進変化を追跡する、
ことを特徴とする請求項8に記載の作動方法。 - 前記強調基準画像は、前記基準画像の1又は2以上の特性を前記断片内画像の1又は2以上の特性と組み合わせることによって発生されることを特徴とする請求項14に記載の作動方法。
- メモリと、
治療計画画像を含む患者の基準画像と該患者の断片内画像の間での変換を決定する第1の画像見当合わせを行い、該基準画像及び該断片内画像が該患者のターゲット位置を含む3次元(3D)画像であり、
前記断片内画像に対する第1のデジタル再構成放射線写真(DRR)を通じて前記患者の該断片内画像と2次元(2D)断片内X線画像の間での変換を決定する第2の画像見当合わせを行い、かつ
前記患者の治療中に、前記第1の画像見当合わせ及び前記第2の画像見当合わせに基づいて一定期間にわたって前記ターゲット位置で少なくとも並進変化を追跡する、
ように前記メモリと作動的に結合された処理デバイスと、
を含むことを特徴とするシステム。 - 前記断片内画像は、キロボルト円錐ビームコンピュータ断層映像(kV-CBCT)画像、メガボルト円錐ビームコンピュータ断層映像(MV-CBCT)画像、メガボルトコンピュータ断層映像(MVCT)画像、又はヘリカルkV-CT画像のうちの1つであることを特徴とする請求項16に記載のシステム。
- 前記処理デバイスは、更に、
前記第1のDRRに基づいて前記患者に関連付けられた基準配置の変化を検出し、かつ
前記基準配置の変化に対処するために前記患者の治療送出に関連付けられた追跡アルゴリズムを修正する、
ことを特徴とする請求項16に記載のシステム。 - 処理デバイスによって実行された時に、
処理デバイスにより、治療計画画像を含む患者の基準画像と該患者の断片内画像の間での変換を決定する第1の画像見当合わせを行い、該基準画像及び該断片内画像が該患者のターゲット位置を含む3次元(3D)画像であり、
前記処理デバイスにより、前記断片内画像に対する第1のデジタル再構成放射線写真(DRR)を通じて前記患者の該断片内画像と2次元(2D)断片内X線画像の間での変換を決定する第2の画像見当合わせを行い、かつ
前記患者の治療中に、前記第1の画像見当合わせ及び前記第2の画像見当合わせに基づいて一定期間にわたって前記ターゲット位置で少なくとも並進変化を追跡する、
ことを前記処理デバイスに行わせる命令、
を含むことを特徴とする非一時的コンピュータ可読媒体。 - 前記処理デバイスは、更に、
前記患者の強調された基準画像と前記断片内X線画像の間での変換を該強調基準画像の第2のDRRを通じて決定する第3の画像見当合わせを行い、かつ
前記患者の治療中に、前記第3の見当合わせに基づいて一定期間にわたって前記ターゲット位置で少なくとも前記並進変化を追跡する、
ことを特徴とする請求項19に記載の非一時的コンピュータ可読媒体。 - 前記基準画像、前記断片内画像、及び前記断片内X線画像は、ヘリカル放射線送出システムの撮像ソースによって又は前記患者に対する異なる位置での1又は2以上の撮像ソースによって発生されることを特徴とする請求項19に記載の非一時的コンピュータ可読媒体。
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