JP7402875B2 - 自動分析装置 - Google Patents
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- G—PHYSICS
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- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
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- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1095—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/4022—Concentrating samples by thermal techniques; Phase changes
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/44—Sample treatment involving radiation, e.g. heat
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- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N30/02—Column chromatography
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N35/00584—Control arrangements for automatic analysers
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
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- G01—MEASURING; TESTING
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- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/025—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes
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- G—PHYSICS
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- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
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- G01N1/4022—Concentrating samples by thermal techniques; Phase changes
- G01N2001/4027—Concentrating samples by thermal techniques; Phase changes evaporation leaving a concentrated sample
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- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
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- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00178—Special arrangements of analysers
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- G—PHYSICS
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00346—Heating or cooling arrangements
- G01N2035/00356—Holding samples at elevated temperature (incubation)
- G01N2035/00376—Conductive heating, e.g. heated plates
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- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
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- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Quality & Reliability (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Sampling And Sample Adjustment (AREA)
Description
図1は、本発明の実施例1に係る自動分析装置の全体構成を概略的に示す図である。
次に、本発明の実施例2について説明する。
次に、本発明野実施例3について説明する。
次に、本発明の実施例4について説明する。
差分比率(%)=│1-(取得したデータ)/(判定用基準データ)│×100 ・・・(1)
Claims (9)
- 試料中の分析対象成分を抽出した抽出液を蒸発させて前記分析対象成分を濃縮する濃縮処理を行う蒸発濃縮部と、
前記試料中の分析対象成分を分析する分析部と、
前記蒸発濃縮部及び前記分析部の動作を制御する制御部と、
を備える自動分析装置において、
前記制御部は、前記試料中の分析対象成分に対して蒸発濃縮処理を行うか否かを判定し、蒸発濃縮処理を行うと判定した試料に対して前記蒸発濃縮部により前記試料中の分析対象成分を濃縮させ、
前記抽出液は内部標準物質を含み、
前記蒸発濃縮部により前記濃縮処理が行われた前記抽出液に濃縮比率算出用標準物質を含む希釈液を添加し、
前記分析部により、前記分析対象成分、前記内部標準物質、及び、前記濃縮比率算出用標準物質の信号量を検出し、
前記制御部が、予め取得した前記内部標準物質及び前記濃縮比率算出用標準物質の信号量である判定用基準データと、検出した前記信号量とから、前記抽出液の濃縮比率を算出することを特徴とする自動分析装置。 - 請求項1に記載の自動分析装置において、
前記蒸発濃縮部は、前記抽出液を加熱して蒸発させる加熱部と、
前記加熱部により発生した蒸気を吸引する排気部と、を有することを特徴とする自動分析装置。 - 請求項2に記載の自動分析装置において、
前記蒸発濃縮部は、前記制御部が、蒸発濃縮を行わないと判定した試料を待機させる待機部を、さらに有することを特徴とする自動分析装置。 - 請求項2に記載の自動分析装置において、
前記排気部は、前記加熱部と一定距離離間した第1の位置と、前記加熱部と密接する第2の位置との間を移動し、
前記制御部は、
前記蒸発濃縮処理を行わない際には、前記第1の位置に前記排気部を配置し、
前記蒸発濃縮処理を行う際には、前記第2の位置まで前記排気部を移動させることを特徴とする自動分析装置。 - 請求項2に記載の自動分析装置において、
前記抽出液は、容器に収容され、
前記加熱部は、前記容器を受容する容器受容部と、前記容器受容部に収容された前記容器を下方から押し上げるエジェクタピンを有することを特徴とする自動分析装置。 - 請求項2に記載の自動分析装置において、
前記抽出液は、容器に収容され、
前記加熱部を、前記容器と接触せず、前記容器内の抽出液を加熱しない非加熱位置と、前記容器に接触させる加熱位置との間を移動させる可動部を備えることを特徴とする自動分析装置。 - 請求項2に記載の自動分析装置において、
前記加熱部は、蒸発濃縮エリア内に配置され、前記蒸発濃縮エリアを開閉する開閉部を備え、前記排気部は、前記蒸発濃縮エリア内を排気することを特徴とする自動分析装置。 - 請求項1に記載の自動分析装置において、
表示部を備え、前記制御部は、前記抽出液の濃縮比率から蒸発濃縮処理が十分か否かを判定し、不十分であると判定すると、蒸発濃縮処理が不十分であることを示すアラームを前記表示部に表示させるこことを特徴とする自動分析装置。 - 請求項2に記載の自動分析装置において、
蒸発濃縮処理対象の試料と、蒸発濃縮処理を行わない試料とを混在して一定間隔で連続的に処理することを特徴とする自動分析装置。
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JP2019125016 | 2019-07-04 | ||
JP2019125016 | 2019-07-04 | ||
PCT/JP2020/026012 WO2021002431A1 (ja) | 2019-07-04 | 2020-07-02 | 自動分析装置 |
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JPWO2021002431A5 JPWO2021002431A5 (ja) | 2023-01-25 |
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US (1) | US20220268798A1 (ja) |
EP (1) | EP3995832A4 (ja) |
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WO2022230282A1 (ja) * | 2021-04-27 | 2022-11-03 | 株式会社日立ハイテク | 自動分析装置 |
CN118103713A (zh) * | 2021-10-25 | 2024-05-28 | 株式会社日立高新技术 | 自动分析装置的控制方法、自动分析装置 |
WO2023095560A1 (ja) * | 2021-11-24 | 2023-06-01 | 株式会社日立ハイテク | 自動分析装置 |
CN116139534A (zh) * | 2023-01-14 | 2023-05-23 | 广东青云山药业有限公司 | 用于丹参提取的自动逆流提取装置的控制方法及*** |
Citations (5)
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JP2009042117A (ja) | 2007-08-09 | 2009-02-26 | Olympus Corp | 恒温槽および自動分析装置 |
JP2013174488A (ja) | 2012-02-24 | 2013-09-05 | Panasonic Corp | 揮発性物質濃縮方法 |
US20160346712A1 (en) | 2016-08-09 | 2016-12-01 | Parto Negar Persia Co. | Automated solid phase extraction |
JP2018205046A (ja) | 2017-05-31 | 2018-12-27 | シスメックス株式会社 | 試料調製装置、試料調製システム、試料調製方法及び粒子分析装置 |
JP2019505773A (ja) | 2015-12-18 | 2019-02-28 | エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト | 自動化された臨床診断システムおよび方法 |
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JP3295014B2 (ja) * | 1997-03-19 | 2002-06-24 | 株式会社大日本精機 | 液体試料中の成分物質の自動抽出装置および液体試料中の成分物質の自動濃度測定装置 |
JP3673789B2 (ja) * | 2003-03-31 | 2005-07-20 | 株式会社日立製作所 | 気化ガス検出方法および気化ガス検出装置 |
US10124270B2 (en) * | 2011-07-26 | 2018-11-13 | Shimadzu Corporation | Gas blowing vaporizing and drying device |
-
2020
- 2020-07-02 JP JP2021529185A patent/JP7402875B2/ja active Active
- 2020-07-02 US US17/622,908 patent/US20220268798A1/en active Pending
- 2020-07-02 CN CN202080047940.XA patent/CN114072679A/zh active Pending
- 2020-07-02 EP EP20834676.7A patent/EP3995832A4/en active Pending
- 2020-07-02 WO PCT/JP2020/026012 patent/WO2021002431A1/ja unknown
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2009042117A (ja) | 2007-08-09 | 2009-02-26 | Olympus Corp | 恒温槽および自動分析装置 |
JP2013174488A (ja) | 2012-02-24 | 2013-09-05 | Panasonic Corp | 揮発性物質濃縮方法 |
JP2019505773A (ja) | 2015-12-18 | 2019-02-28 | エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト | 自動化された臨床診断システムおよび方法 |
US20160346712A1 (en) | 2016-08-09 | 2016-12-01 | Parto Negar Persia Co. | Automated solid phase extraction |
JP2018205046A (ja) | 2017-05-31 | 2018-12-27 | シスメックス株式会社 | 試料調製装置、試料調製システム、試料調製方法及び粒子分析装置 |
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US20220268798A1 (en) | 2022-08-25 |
WO2021002431A1 (ja) | 2021-01-07 |
JPWO2021002431A1 (ja) | 2021-01-07 |
EP3995832A1 (en) | 2022-05-11 |
CN114072679A (zh) | 2022-02-18 |
EP3995832A4 (en) | 2023-08-16 |
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