JP7378400B2 - 注射デバイスに取り付けるセンサデバイス - Google Patents
注射デバイスに取り付けるセンサデバイス Download PDFInfo
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- JP7378400B2 JP7378400B2 JP2020536175A JP2020536175A JP7378400B2 JP 7378400 B2 JP7378400 B2 JP 7378400B2 JP 2020536175 A JP2020536175 A JP 2020536175A JP 2020536175 A JP2020536175 A JP 2020536175A JP 7378400 B2 JP7378400 B2 JP 7378400B2
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Images
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Description
な付加的デバイスの電力消費を最小限にするための方法が必要とされている。
入器などの他のタイプの薬物送達デバイスとも、等しく良好に展開できる。
スクリーンであってもよい。たとえば、ディスプレイユニット4は、補助デバイス2の使用者にスケジュール上の次の注射の時間および日付を示す。注射デバイス10の動作中、補助デバイス2は、以下でより詳細に記載するように、使用者を支援するための情報を表示することもできる。
実施形態では、光学センサ26は、色を検出するように構成されている単純な光度計であってもよい。いくつかの他の実施形態では、薬剤を識別する情報100はQRコードまたは他の類似のコード化された情報であってもよく、光学センサ26はカメラまたはQRコードリーダであってもよい。さらに、光学センサ26の読み取りを改善するための、1つまたはそれ以上の光源を備えてもよい。光源は、光学センサ26による色の検出を改善するために、特定の波長またはスペクトルの光を提供してもよい。光源を、たとえばハウジング11の湾曲に起因する、望まれない反射が回避または低減されるような方法で配置してもよい。例示の実施形態では、光学センサ26は、注射デバイスおよび/またはその中に含まれている薬剤に関連するコード100(たとえばバーコード、これはたとえば1次元また2次元バーコードでありうる)を検出するように構成されているカメラユニットである。このコード100をたとえば、ハウジング11上に、または注射デバイス10に含まれている薬剤容器上に位置することができるが、これはいくつか例を挙げたに過ぎない。このコード100はたとえば、注射デバイスおよび/もしくは薬剤のタイプ、ならびに/またはさらなる特性(たとえば有効期限)を示すことができる。このコード100はQRコード100であってもよい。QRコードは一般に黒色および白色であり、したがって光学センサ26側での色検出は必要とされない。このことにより、光学センサ26を簡単かつ安価に製造することが可能になる。
構成要素であり、また実施形態によっては、このメモリは低電力プロセッサ112と一体であるかまたは非接触加速度センサ110と一体である。言い換えれば、低電力プロセッサ112を少なくとも1つの加速プロファイルを用いて事前にプログラムしてもよく、または、低電力プロセッサ112は、典型的なキャップ取り外しの動きを示す少なくとも1つの加速プロファイルにアクセスできてもよい。
ロファイルの多数の異形も記憶することができる。
きプロファイルに照らしてチェックすることによって、行うことができる。受信した信号が典型的な向きを示していると低電力プロセッサ112が判定する場合、低電力プロセッサ112は、主電子回路24に起動信号を送る。受信した信号が注射デバイス10が典型的な向きではないことを示していると低電力プロセッサ112が判定する場合(たとえばそれが特定のプロファイルと相関しない場合)には、低電力プロセッサ112は主電子回路24に起動信号を送らなくてもよく、または、低電力プロセッサ112は、注射デバイス10が典型的な向きではないことを示す信号を送ってもよい。
信する。工程502では、1つまたはそれ以上の加速プロファイルにアクセスする。既に記載したように、低電力プロセッサ112または非接触加速度センサ110は、加速プロファイルを用いて事前にプログラムすることができる。代替として、低電力プロセッサ112は、メモリにアクセスして加速プロファイルを読み出してもよい。工程504では、非接触加速度センサから出力された信号を1つまたはそれ以上の加速プロファイルと比較して、一致を判定する。一致は必ずしも厳密である必要はなく、各加速プロファイルの様々なセクションについて公差を設定してもよい。工程506では、低電力プロセッサ112は、比較に基づいて、薬物送達デバイスの外側針キャップが取り外されていると判定する。
)。
ば、ディスプレイは使用者に、注射デバイスをいつ交換すべきか(たとえばいつ空になるか)を示すことができる。
ド)、リラグルチド(ビクトーザ(Victoza)(登録商標))、セマグルチド、タスポグルチド、アルビグルチド(シンクリア(Syncria)(登録商標))、デュラグルチド(トルリシティ(Trulicity)(登録商標))、rエキセンジン-4、CJC-1134-PC、PB-1023、TTP-054、ラングレナチド/HM-11260C、CM-3、GLP-1エリゲン、ORMD-0901、NN-9924、NN-9926、NN-9927、ノデキセン、ビアドール-GLP-1、CVX-096、ZYOG-1、ZYD-1、GSK-2374697、DA-3091、MAR-701、MAR709、ZP-2929、ZP-3022、TT-401、BHM-034、MOD-6030、CAM-2036、DA-15864、ARI-2651、ARI-2255、エキセナチド-XTENおよびグルカゴン-Xtenである。
な抗体フラグメントとしては、たとえば、Fabフラグメント、F(ab’)2フラグメント、scFv(一本鎖Fv)フラグメント、線状抗体、単一特異的または多重特異的な抗体フラグメント、たとえば、二重特異的、三重特異的、四重特異的および多重特異的抗体(たとえば、ダイアボディ、トリアボディ、テトラボディ)、1価または多価抗体フラグメント、たとえば、2価、3価、4価および多価の抗体、ミニボディ、キレート化組換え抗体、トリボディまたはビボディ、イントラボディ、ナノボディ、小モジュール免疫医薬(SMIP)、結合ドメインイムノグロブリン融合タンパク質、ラクダ化抗体、およびVHH含有抗体が挙げられる。抗原結合抗体フラグメントの追加の例は当技術分野で公知である。
Claims (16)
- 薬物送達デバイスの遠位端に解放可能に取り付けられるように構成されている補助デバイスであって:
主電子回路と;
補助デバイスの表面または中に位置する非接触加速度センサであって、薬物送達デバイスの近位端の方に向けられている非接触加速度センサと;
該非接触加速度センサから出力された信号を受信し;
該非接触加速度センサから出力された信号を、低電力プロセッサが読み取り可能なメモリに記憶された1つまたはそれ以上の加速プロファイルと比較し;
該信号と該1つまたはそれ以上の加速プロファイルとの比較に基づいて、薬物送達デバイスの外側針キャップが取り外されていると判定し;
薬物送達デバイスの外側針キャップが取り外されていると判定したことに応答して、補助デバイスの主電子回路にウェイクアップ信号を送るように構成されている低電力プロセッサ、ここで、該プロセッサは、該信号と該1つまたはそれ以上の加速プロファイルとの比較が、外側針キャップを近位方向へ動かす際の加速および続く外側針キャップを近位方向へ動かす際の減速を示すときに外側針キャップが取り外されていると判定するように構成されている、と
を含む、前記補助デバイス。 - メモリは非接触加速度センサから出力された信号を1つまたはそれ以上の加速プロファイルと比較するためのソフトウェアを記憶している、請求項1に記載の補助デバイス。
- 1つまたはそれ以上の加速プロファイルが非接触加速度センサから出力された信号に基づいて更新される機械学習モードで動作するように構成されている、請求項1または請求項2に記載の補助デバイス。
- 1つまたはそれ以上の加速プロファイルの各々は、異なるタイプの薬物送達デバイスに関連している、請求項1~3のいずれか1項に記載の補助デバイス。
- 1つまたはそれ以上の加速プロファイルのうちの第1のものは、近位方向への急激な加速と近位方向への急激な減速の間のほぼ一定の速度を示すデータをさらに含む、請求項1に記載の補助デバイス。
- 1つまたはそれ以上の加速プロファイルのうちの第1のものは、速度の総変化が遠位方向への動きを示すまで近位方向への急激な減速が継続することを示すデータをさらに含む、請求項1に記載の補助デバイス。
- 1つまたはそれ以上の加速プロファイルのうちの第2のものは、近位方向への急激な加速および続く急な停止を示すデータを含む、請求項1に記載の補助デバイス。
- 非接触加速度センサは、使用者の手が外側針キャップを取り外す際のその手の動きを検出するような位置にある、請求項1~7のいずれか1項に記載の補助デバイス。
- 補助デバイスの表面または中に位置する位置センサをさらに含み、該位置センサは、薬物送達デバイスの近位端の方に向けられており、使用者の手および/または薬物送達デバイスの位置および/または向きを示す信号を出力するように構成されている、請求項8に記載の補助デバイス。
- 非接触加速度センサは電磁反射センサである、請求項1~9のいずれか1項に記載の補助デバイス。
- 非接触加速度センサは光学センサまたは赤外センサである、請求項10に記載の補助デバイス。
- 位置センサは受動赤外センサまたは加速度計である、請求項8または請求項9に記載の補助デバイス。
- ロックセンサをさらに含み、該ロックセンサは、補助デバイスが薬物送達デバイスに固着されているか否かを示す信号を出力するように構成されている、請求項1~12のいずれか1項に記載の補助デバイス。
- データを1つまたはそれ以上の外部のデバイスに送信するように構成されているワイヤレスユニットをさらに含む、請求項1~13のいずれか1項に記載の補助デバイス。
- 薬物送達デバイスの遠位端に解放可能に取り付けられるように構成されている補助デバイスを動作させる方法であって:
該補助デバイスの表面または中に位置し信号を出力するため薬物送達デバイスの近位端の方に向けられている非接触加速度センサを提供することと;
使用者が該薬物送達デバイスの外側針キャップを取り外す際の、該非接触加速度センサに対する使用者の手の速度の変化を示す非接触加速度センサからの信号を出力することと;
該非接触加速度センサから出力された信号を低電力プロセッサにおいて受信することと;
該低電力プロセッサが:
1つまたはそれ以上の加速プロファイルにアクセスし;
該非接触加速度センサから出力された信号を低電力プロセッサが読み取り可能なメモリに記憶された1つまたはそれ以上の加速プロファイルと比較し;
該信号と該1つまたはそれ以上の加速プロファイルとの比較が、外側針キャップを近位方向へ動かす際の加速および続く外側針キャップを近位方向へ動かす際の減速を示すとき
に外側針キャップが取り外されていると判定し;
該薬物送達デバイスの外側針キャップが取り外されていると判定したことに応答して、補助デバイスの主電子回路にウェイクアップ信号を送ることと
を含む、前記方法。 - 請求項1~14のいずれか1項に記載の補助デバイスと薬物送達デバイスとを含むシステム。
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CN112604084B (zh) * | 2020-12-07 | 2023-04-07 | 杭州慧钥医疗器械科技有限公司 | 音频数据的采集方法、装置、设备及可读存储介质 |
CN117957029A (zh) * | 2021-09-24 | 2024-04-30 | 赛诺菲 | 被提供用于药物递送装置或药物递送附加装置的具有电池寿命优化的电子装置 |
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US11672916B2 (en) | 2023-06-13 |
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