JP7209374B2 - フィルタを通して廃棄流体を除去するための方法および装置を含むプロセッサフィルタ配置 - Google Patents
フィルタを通して廃棄流体を除去するための方法および装置を含むプロセッサフィルタ配置 Download PDFInfo
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Description
a)上記フィルタ要素の上面上に粒子を堆積させるステップ、
b)上記フィルタ要素の上記上面を通して洗浄流体を提供して、上記フィルタ要素を通して小径粒子を排除するステップであって、その後、使用済みの洗浄流体が廃棄流体になる、ステップ、
c)槽に上記廃棄流体を回収するステップ、
d)上記槽における廃棄流体の量を測定し、所定量の廃棄流体に到達すると、洗浄を中止するステップ、および
e)上記槽における廃棄流体の量が上記所定量の廃棄流体未満であれば、ステップb)からステップd)を繰り返すステップ
を含む方法を対象とする。
Claims (20)
- 光学分析のために生体試料を処理するためのシステムであって、
a)複数のカートリッジであって、各カートリッジが、流体と粒子の混合物を受容するための試料供給容器を有し、かつ各カートリッジが、前記流体と粒子の混合物から濾過された粒子を受容するためのキュベットを有する、複数のカートリッジ、
b)前記複数のカートリッジを保持するためのレシーバを備えるカートリッジマガジン、
c)複数のスロットが貫通したカセットファンであって、各スロットは、フィルタカセットを保持するように適応させ、該カセットファンが、選択されたカートリッジと整列する第一の位置から該カートリッジから離れる第二の位置まで移動可能である、カセットファン、および
d)前記ファン内に各フィルタカセットを固定するようにかつ該フィルタカセットを作動させるように適応させた、前記カセットファンの上方に配置されるカセットクランプ
を含むシステム。 - 複数のフィルタカセットをさらに含み、各フィルタカセットが、一つのカートリッジにおける試料供給容器から流体と粒子の混合物を受容するための入口と、前記流体から前記粒子を濾過するための配置と、濾過された前記粒子を同カートリッジにおけるキュベットへ排出するための出口とを有する、請求項1に記載のシステム。
- 各フィルタカセットが、各フィルタカセット内の複数のステップの濾過工程を実行するためのスライド弁を有する、請求項2に記載のシステム。
- 内部に搭載したフィルタカセットのスライド弁を作動させるための前記カセットクランプ上に搭載されたモータをさらに含む請求項3に記載のシステム。
- 第一の位置における前記カセットファンが、内部にフィルタカセットを有し、各フィルタカセットに関して、前記入口が、カートリッジの前記試料供給容器と整列され、前記出口が、同カートリッジの前記キュベットと整列される、請求項2に記載のシステム。
- クランプ第一位置において、前記カセットクランプが、各フィルタカセットに対して固定されて、前記カセットファン内に該フィルタカセットを固定する、請求項5に記載のシステム。
- 前記カセットクランプは、前記クランプ第一位置において、前記フィルタカセットが前記流体と粒子の混合物を濾過するように作動されるように、各フィルタカセットの制御ポートに流体接続される、請求項6に記載のシステム。
- 洗浄流体が、前記フィルタカセットにおけるフィルタを洗浄するために使用され、使用される洗浄流体の量を測定しかつ所定量の洗浄流体が使用されたときに洗浄サイクルを停止するための測定デバイスをさらに含む、請求項7に記載のシステム。
- 前記測定デバイスが、静電容量式液体センサ、超音波センサ、および水圧センサのうちの一つから選択される、請求項8に記載のシステム。
- 第二の位置における前記カセットファンが、前記カートリッジマガジンから離れる装填/取出領域において内部にフィルタカセットを有する、請求項2に記載のシステム。
- 前記カセットファンにおける空のスロットに未使用のフィルタカセットを移す機械アーム上に未使用のフィルタカセットの在庫を提供するためのフィルタカセット供給マガジン、および使用済みフィルタカセットのための保管場所を提供するためのフィルタカセット保管マガジンをさらに含み、前記機械アームは、前記カセットファンから前記フィルタカセット保管マガジンに使用済みフィルタカセットを移すように適応させる、請求項10に記載のシステム。
- 前記カセットファンおよび前記カートリッジマガジンは、該カセットファンが該カートリッジマガジンに対して特定の位置に割り出しされ得るように、互いに独立して移動する、請求項1に記載のシステム。
- 前記カセットファンおよび前記カートリッジマガジンが共通の軸周りに回転する、請求項12に記載のシステム。
- 前記カートリッジマガジンにおけるレシーバの数が前記カセットファンにおけるスロットの数よりも多い、請求項1に記載のシステム。
- 光学分析のために生体試料を処理するための方法であって、
a)カートリッジマガジンのレシーバ内に複数のカートリッジを保持するステップであって、各カートリッジが、流体と粒子の混合物を受容するための試料供給容器を有し、かつ各カートリッジが、前記流体と粒子の混合物から濾過された粒子を受容するためのキュベットを有する、ステップ、
b)複数のスロットが貫通しているカセットファンであって、各スロットは、フィルタカセットを保持するように適応させるカセットファンを用いて、該カセットファンを前記マガジンにおける選択されたカートリッジと整列する第一の位置に移動させるステップ、および
c)前記カセットファンの上方にカセットクランプを配置し、かつ該カセットクランプを用いて前記ファン内に各フィルタカセットを固定し、かつ該フィルタカセットを作動させるステップ
を含む方法。 - 前記カセットクランプを配置して前記カセットを固定しかつ該フィルタカセットを作動させた後、各使用済みのフィルタカセットを解放し、かつ使用済みのフィルタカセットを取り出して前記カセットファン内に新しいフィルタカセットを再装填するために前記マガジンから離れる第二の位置まで該カセットファンを移動させるステップをさらに含む、請求項15に記載の方法。
- フィルタ要素が夫々設けられた複数のフィルタカセットと、各前記フィルタ要素の上面を通して小径粒子を洗浄するための装置と、を更に備え、
前記装置は、
a)前記フィルタ要素の前記上面を通して洗浄流体を提供して、該フィルタ要素を通して小径粒子を排除するための洗浄流体源であって、その後、使用済みの前記洗浄流体が廃棄流体になる、洗浄流体源、
b)前記廃棄流体を回収するために前記フィルタ要素と流体接続している槽、
c)前記槽における廃棄流体の量を測定し、所定量の廃棄流体に到達したら、洗浄を中止するための測定デバイス、および
d)前記フィルタ要素から粒子を接線方向に拭い去るために前記フィルタ要素の前記上面と流体連通している溶出流体源
を含む、請求項1に記載のシステム。 - 前記測定デバイスが、静電容量式液体センサ、超音波センサ、および水圧センサからの一つである、請求項17に記載のシステム。
- a)各前記フィルタカセットに設けられたフィルタ要素の上面上に粒子を堆積させるステップ、
b)前記フィルタ要素の前記上面を通して洗浄流体を提供して、前記フィルタ要素を通して小径粒子を排除するステップであって、その後、使用済みの前記洗浄流体が廃棄流体になる、ステップ、
c)槽に前記廃棄流体を回収するステップ、
d)前記槽における廃棄流体の量を測定し、所定量の廃棄流体に到達すると、洗浄を中止するステップ、および
e)前記槽における廃棄流体の量が前記所定量の廃棄流体未満であれば、ステップb)からステップd)を繰り返すステップ
をさらに含む、請求項15に記載の方法。 - 前記廃棄流体の量が前記所定量以上になった後、溶出流体を用いて前記フィルタ要素の上面を接線方向に拭って前記堆積させた粒子を排除するステップをさらに含む、請求項19に記載の方法。
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