JP6926084B2 - ニコチン粉末送達システム - Google Patents
ニコチン粉末送達システム Download PDFInfo
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- JP6926084B2 JP6926084B2 JP2018529303A JP2018529303A JP6926084B2 JP 6926084 B2 JP6926084 B2 JP 6926084B2 JP 2018529303 A JP2018529303 A JP 2018529303A JP 2018529303 A JP2018529303 A JP 2018529303A JP 6926084 B2 JP6926084 B2 JP 6926084B2
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- nicotine
- nicotine powder
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0033—Details of the piercing or cutting means
- A61M15/0035—Piercing means
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
- A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
- A24F40/40—Constructional details, e.g. connection of cartridges and battery parts
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
- A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
- A24F40/20—Devices using solid inhalable precursors
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
- A24F42/00—Simulated smoking devices other than electrically operated; Component parts thereof; Manufacture or testing thereof
- A24F42/20—Devices without heating means
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
- A24F42/00—Simulated smoking devices other than electrically operated; Component parts thereof; Manufacture or testing thereof
- A24F42/60—Constructional details
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
- A61M15/0006—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
- A61M15/0008—Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means rotating by airflow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/0063—Storages for pre-packed dosages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/06—Inhaling appliances shaped like cigars, cigarettes or pipes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2206/00—Characteristics of a physical parameter; associated device therefor
- A61M2206/10—Flow characteristics
- A61M2206/16—Rotating swirling helical flow, e.g. by tangential inflows
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Description
Claims (17)
- ニコチン粉末送達システムであって、
吸入器物品であって、
マウスピース部分と遠位端部分の間に延びる吸入器本体と、
前記吸入器本体内、および前記マウスピース部分と前記遠位端部分の間に配置されたニコチン粉末容器と、
前記吸入器本体を通り前記ニコチン粉末容器内に延びる空気吸込み口ポートと、
前記ニコチン粉末容器を前記マウスピースの近位端と流体接続させるマウスピース空気チャネルと、
前記遠位端部分に配置されたエンドキャップ要素であって、前記エンドキャップ要素が、貫通要素が取り除かれたときに貫通要素によって形成される穴を実質的に塞ぐ貫通可能材料で形成されるものとを備えるものと、
前記ニコチン粉末容器内に配置されているニコチン粉末を含むニコチン粉末カプセルであって、空気が前記空気吸込み口ポートから前記マウスピース空気チャネルに流れる時、前記ニコチン粉末カプセルが長軸方向軸の周りを回転するものとを備え、
貫通要素が前記エンドキャップ要素を通過することができ、かつ前記ニコチン粉末カプセルの壁を通る単一の開口部を形成する、ニコチン粉末送達システム。 - 前記空気吸込み口ポートが前記ニコチン粉末カプセルの前記長軸方向軸からオフセットされている、請求項1に記載のニコチン粉末送達システム。
- 前記ニコチン粉末容器が円形の断面形状を有し、かつ前記空気吸込み口ポートが前記ニコチン粉末容器に正接する、請求項1または2に記載のニコチン粉末送達システム。
- 前記空気吸込み口ポートが第一の空気吸込み口ポートおよび第二の空気吸込み口ポートを備える、請求項1〜3のいずれか一項に記載のニコチン粉末送達システム。
- 前記ニコチン粉末容器が円形の断面形状を有し、かつ前記第一の空気吸込み口ポートが前記ニコチン粉末容器に正接し、前記第二の空気吸込み口ポートが前記ニコチン粉末容器に正接する、請求項4に記載のニコチン粉末送達システム。
- 前記第一の空気吸込み口ポートが前記第二の空気吸込み口ポートに対向する、請求項5に記載のニコチン粉末送達システム。
- 前記ニコチン粉末容器が円形の断面形状および第一の直径を有し、また前記ニコチン粉末カプセルが前記第一の直径よりも小さい第二の直径を有し、前記第二の直径が前記第一の直径約80%〜約99%の範囲であるか、または前記第二の直径が前記第一の直径の約90%〜約98%の範囲である、請求項1〜6のいずれか一項に記載のニコチン粉末送達システム。
- エンドキャップ要素が約120mm WGよりも大きな引き出し抵抗(RTD)を有し、前記ニコチン粉末送達システムが約50mm WG〜約100mm WGの範囲の引き出し抵抗(RTD)を有する、請求項1〜7のいずれか一項に記載のニコチン粉末送達システム。
- 前記ニコチン粉末がニコチンを含む粒子を含み、約10マイクロメートル以下、または約5マイクロメートル以下、または約1マイクロメートル〜約3マイクロメートルの範囲の空気動力学的中央粒子径を有する、請求項1〜8のいずれか一項に記載のニコチン粉末送達システム。
- 前記ニコチンを含む粒子がニコチン塩またはニコチン塩水和物を含む、請求項9に記載のニコチン粉末送達システム。
- 前記ニコチンを含む粒子が、ロイシン被覆またはL−ロイシン被覆などのアミノ酸被覆を含む、請求項9または10に記載のニコチン粉末送達システム。
- 前記ニコチン粉末カプセルが、風味を含む粒子を含み、約20マイクロメートル以上、または約50マイクロメートル〜約150マイクロメートルの範囲の空気動力学的中央粒子径を有する、請求項9または10に記載のニコチン粉末送達システム。
- 前記エンドキャップ要素を通過し、前記ニコチン粉末カプセルに単一の開口部を貫通させる貫通要素をさらに備える、請求項1〜12のいずれか一項に記載のニコチン粉末送達システム。
- 請求項1〜13のいずれか一項に記載の複数のニコチン粉末送達システムを含む物品であって、貫通要素が前記物品に固定され、かつ前記貫通要素が前記エンドキャップ要素を通過し、前記ニコチン粉末カプセルに単一の孔を貫通させ、また前記ニコチン粉末送達システムが消費のために前記貫通要素および物品から取り外される、物品。
- 請求項1〜14のいずれか一項に記載の複数の前記ニコチン粉末送達システムを含む物品であって、複数の貫通要素が前記物品に固定され、前記貫通要素の数が前記ニコチン粉末送達システムの数と等しい、物品。
- 前記複数の貫通要素のそれぞれが、対応するニコチン粉末カプセルに見当合わせされて挿入され、前記ニコチン粉末カプセル内に単一の開口部を形成する、請求項15に記載の物品。
- エンドキャップ要素が酢酸セルロースを含む、請求項1〜13のいずれか1項に記載のニコチン粉末送達システム。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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JP2021128118A JP7238043B2 (ja) | 2015-12-24 | 2021-08-04 | ニコチン粉末送達システム |
Applications Claiming Priority (3)
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EP15202712.4 | 2015-12-24 | ||
EP15202712 | 2015-12-24 | ||
PCT/IB2016/057455 WO2017109626A1 (en) | 2015-12-24 | 2016-12-08 | Nicotine powder delivery system |
Related Child Applications (1)
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JP2021128118A Division JP7238043B2 (ja) | 2015-12-24 | 2021-08-04 | ニコチン粉末送達システム |
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JP2019506914A JP2019506914A (ja) | 2019-03-14 |
JP6926084B2 true JP6926084B2 (ja) | 2021-08-25 |
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JP2018529303A Active JP6926084B2 (ja) | 2015-12-24 | 2016-12-08 | ニコチン粉末送達システム |
JP2021128118A Active JP7238043B2 (ja) | 2015-12-24 | 2021-08-04 | ニコチン粉末送達システム |
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JP2021128118A Active JP7238043B2 (ja) | 2015-12-24 | 2021-08-04 | ニコチン粉末送達システム |
Country Status (16)
Country | Link |
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US (2) | US11338099B2 (ja) |
EP (2) | EP3393560B1 (ja) |
JP (2) | JP6926084B2 (ja) |
KR (1) | KR102649827B1 (ja) |
CN (2) | CN108463262B (ja) |
AU (1) | AU2016379094A1 (ja) |
BR (1) | BR112018011496A2 (ja) |
CA (1) | CA3008211A1 (ja) |
IL (1) | IL259943A (ja) |
MX (1) | MX2018007510A (ja) |
MY (1) | MY188235A (ja) |
PH (1) | PH12018501143A1 (ja) |
RU (2) | RU2735143C2 (ja) |
SG (1) | SG11201805072PA (ja) |
WO (1) | WO2017109626A1 (ja) |
ZA (1) | ZA201803582B (ja) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2018220476A1 (en) * | 2017-05-31 | 2018-12-06 | Philip Morris Products S.A. | Nicotine powder consumable article |
KR20200023285A (ko) * | 2017-06-28 | 2020-03-04 | 필립모리스 프로덕츠 에스.에이. | 흡입기와 함께 사용하기 위한 입자를 가진 컨테이너 |
CN114642275A (zh) * | 2017-10-25 | 2022-06-21 | 菲利普莫里斯生产公司 | 用于吸入器制品和***的刺穿附件 |
CN109821118A (zh) | 2017-11-23 | 2019-05-31 | 正大天晴药业集团股份有限公司 | 新型肺部药物输送*** |
JP2021509297A (ja) * | 2017-12-28 | 2021-03-25 | フィリップ・モーリス・プロダクツ・ソシエテ・アノニム | 渦トンネルを備えた吸入器 |
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US11925751B2 (en) | 2018-03-26 | 2024-03-12 | Philip Morris Products S.A. | Inhaler with aperatured porous support element |
KR20200131248A (ko) * | 2018-03-26 | 2020-11-23 | 필립모리스 프로덕츠 에스.에이. | 와류 캡슐 공동을 갖는 흡입기 |
KR20210135487A (ko) * | 2019-03-05 | 2021-11-15 | 필립모리스 프로덕츠 에스.에이. | 흡입기 물품용 관통 장치 |
CN114375210A (zh) * | 2019-09-26 | 2022-04-19 | 菲利普莫里斯生产公司 | 具有扭转型远端元件的吸入器制品 |
US20220379051A1 (en) * | 2019-10-25 | 2022-12-01 | Philip Morris Products S.A. | Inhaler article with open distal end, and inhaler system |
EP4048354B1 (en) * | 2019-10-25 | 2023-10-04 | Philip Morris Products S.A. | Inhaler article with tangential airflow end element |
JP2023534514A (ja) * | 2020-07-24 | 2023-08-09 | フィリップ・モーリス・プロダクツ・ソシエテ・アノニム | 吸入器物品 |
EP4228459A1 (en) * | 2020-10-16 | 2023-08-23 | Philip Morris Products S.A. | Aerosol generator with curved chamber |
US20240042146A1 (en) * | 2020-12-18 | 2024-02-08 | Philip Morris Products S.A. | Inhaler article having hollow tubular element |
KR20230156916A (ko) * | 2021-03-16 | 2023-11-15 | 필립모리스 프로덕츠 에스.에이. | 고용량 전달을 위한 흡입기 물품 홀더 |
WO2024091005A1 (ko) * | 2022-10-27 | 2024-05-02 | 주식회사 케이티앤지 | 기침 억제제를 함유한 건조 분말 흡입기용 스틱 및 이를 포함한 건조 분말 흡입기 |
KR20240061134A (ko) * | 2022-10-31 | 2024-05-08 | 주식회사 케이티앤지 | 인헤일러 |
KR20240107439A (ko) * | 2022-12-30 | 2024-07-09 | 주식회사 케이티앤지 | 흡입기 |
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GB201413021D0 (en) * | 2014-02-28 | 2014-09-03 | Beyond Twenty Ltd | Beyond 2 |
RU2696570C2 (ru) * | 2014-04-28 | 2019-08-06 | Филип Моррис Продактс С.А. | Ингалятор никотинового порошка |
JP6712232B2 (ja) * | 2014-04-28 | 2020-06-17 | フィリップ・モーリス・プロダクツ・ソシエテ・アノニム | 風味付きニコチン粉末吸入器 |
EP3157364B1 (en) * | 2014-06-20 | 2018-08-22 | Philip Morris Products S.a.s. | Nicotine powder delivery system with airflow management means |
CN104126878B (zh) | 2014-08-15 | 2017-05-10 | 云南中烟工业有限责任公司 | 一种含微胶囊缓释装置的电子烟及微胶囊 |
KR102672015B1 (ko) * | 2015-12-30 | 2024-06-04 | 필립모리스 프로덕츠 에스.에이. | 액체 전달 요소를 포함하는 에어로졸 발생 물품 |
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SG11201805072PA (en) | 2018-07-30 |
JP2019506914A (ja) | 2019-03-14 |
RU2018126476A3 (ja) | 2020-04-23 |
CN113273731A (zh) | 2021-08-20 |
KR102649827B1 (ko) | 2024-03-21 |
EP3669916B1 (en) | 2023-09-06 |
CA3008211A1 (en) | 2017-06-29 |
EP3669916C0 (en) | 2023-09-06 |
EP3669916A1 (en) | 2020-06-24 |
IL259943A (en) | 2018-07-31 |
RU2735143C2 (ru) | 2020-10-28 |
BR112018011496A2 (pt) | 2018-12-04 |
MX2018007510A (es) | 2018-08-01 |
CN108463262B (zh) | 2021-06-11 |
JP7238043B2 (ja) | 2023-03-13 |
ZA201803582B (en) | 2019-07-31 |
EP3393560B1 (en) | 2020-03-25 |
CN108463262A (zh) | 2018-08-28 |
US20220249786A1 (en) | 2022-08-11 |
US20180369517A1 (en) | 2018-12-27 |
US11338099B2 (en) | 2022-05-24 |
MY188235A (en) | 2021-11-24 |
PH12018501143A1 (en) | 2019-01-21 |
RU2018126476A (ru) | 2020-01-24 |
WO2017109626A1 (en) | 2017-06-29 |
KR20180097534A (ko) | 2018-08-31 |
RU2020133228A (ru) | 2021-01-28 |
EP3393560A1 (en) | 2018-10-31 |
AU2016379094A1 (en) | 2018-06-21 |
JP2021169005A (ja) | 2021-10-28 |
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