JP6845803B2 - 一体化された穿孔要素を備えるエアロゾル発生システム - Google Patents
一体化された穿孔要素を備えるエアロゾル発生システム Download PDFInfo
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- JP6845803B2 JP6845803B2 JP2017546616A JP2017546616A JP6845803B2 JP 6845803 B2 JP6845803 B2 JP 6845803B2 JP 2017546616 A JP2017546616 A JP 2017546616A JP 2017546616 A JP2017546616 A JP 2017546616A JP 6845803 B2 JP6845803 B2 JP 6845803B2
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- GELKBWJHTRAYNV-UHFFFAOYSA-K lithium iron phosphate Chemical compound [Li+].[Fe+2].[O-]P([O-])([O-])=O GELKBWJHTRAYNV-UHFFFAOYSA-K 0.000 description 1
- FUJCRWPEOMXPAD-UHFFFAOYSA-N lithium oxide Chemical compound [Li+].[Li+].[O-2] FUJCRWPEOMXPAD-UHFFFAOYSA-N 0.000 description 1
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- XLTANAWLDBYGFU-UHFFFAOYSA-N methyllycaconitine hydrochloride Natural products C1CC(OC)C2(C3C4OC)C5CC(C(C6)OC)C(OC)C5C6(O)C4(O)C2N(CC)CC31COC(=O)C1=CC=CC=C1N1C(=O)CC(C)C1=O XLTANAWLDBYGFU-UHFFFAOYSA-N 0.000 description 1
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- PIJVFDBKTWXHHD-HIFRSBDPSA-N physostigmine Chemical compound C12=CC(OC(=O)NC)=CC=C2N(C)[C@@H]2[C@@]1(C)CCN2C PIJVFDBKTWXHHD-HIFRSBDPSA-N 0.000 description 1
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- STECJAGHUSJQJN-FWXGHANASA-N scopolamine Chemical compound C1([C@@H](CO)C(=O)O[C@H]2C[C@@H]3N([C@H](C2)[C@@H]2[C@H]3O2)C)=CC=CC=C1 STECJAGHUSJQJN-FWXGHANASA-N 0.000 description 1
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- 229920002379 silicone rubber Polymers 0.000 description 1
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- MKTAGSRKQIGEBH-SSDOTTSWSA-N tebanicline Chemical compound C1=NC(Cl)=CC=C1OC[C@@H]1NCC1 MKTAGSRKQIGEBH-SSDOTTSWSA-N 0.000 description 1
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- 229910052726 zirconium Inorganic materials 0.000 description 1
Images
Classifications
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- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
- A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
- A24F40/40—Constructional details, e.g. connection of cartridges and battery parts
- A24F40/46—Shape or structure of electric heating means
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
- A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
- A24F40/40—Constructional details, e.g. connection of cartridges and battery parts
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
- A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
- A24F40/40—Constructional details, e.g. connection of cartridges and battery parts
- A24F40/42—Cartridges or containers for inhalable precursors
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
- A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
- A24F40/50—Control or monitoring
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
- A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
- A24F40/50—Control or monitoring
- A24F40/57—Temperature control
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/04—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised
- A61M11/041—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters
- A61M11/042—Sprayers or atomisers specially adapted for therapeutic purposes operated by the vapour pressure of the liquid to be sprayed or atomised using heaters electrical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
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- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/0021—Mouthpieces therefor
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
- A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
- A61M15/0033—Details of the piercing or cutting means
- A61M15/0035—Piercing means
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/06—Inhaling appliances shaped like cigars, cigarettes or pipes
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- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
- A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
- A24F40/10—Devices using liquid inhalable precursors
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- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
- A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/82—Internal energy supply devices
- A61M2205/8206—Internal energy supply devices battery-operated
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Catching Or Destruction (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
Description
Claims (14)
- エアロゾル発生システムであって、
発熱体を含むエアロゾル発生装置と、
前記エアロゾル発生装置と係合するよう構成されるエアロゾル発生物品であって、
医薬源と、
揮発性送達促進化合物源と、
前記医薬源および前記揮発性送達促進化合物源をシールする少なくとも1つの壊れやすいバリアとを含むエアロゾル発生物品とを含み、
前記発熱体が、前記エアロゾル発生装置に取り付けられた近位端および前記エアロゾル発生物品に挿入される自由遠位端を備える細長い発熱体であって、ユーザーが前記エアロゾル発生物品を前記エアロゾル発生装置と係合するとき、前記細長い発熱体が、穿孔要素を形成し、前記細長い発熱体が前記少なくとも1つの壊れやすいバリアに穴を開けるよう配置される、エアロゾル発生システム。 - 前記エアロゾル発生物品が、前記医薬源および前記揮発性送達促進化合物源を収容する管状部分を備え、前記少なくとも1つの壊れやすいバリアが、前記管状部分の少なくとも一端にわたって延在する少なくとも1つの壊れやすいバリアを含む、請求項1に記載のエアロゾル発生システム。
- エアロゾル発生システムであって、
発熱体を含むエアロゾル発生装置と、
前記エアロゾル発生装置と係合するよう構成されるエアロゾル発生物品であって、
医薬源と、
揮発性送達促進化合物源と、
前記医薬源および前記揮発性送達促進化合物源を収容する管状部分と、
前記管状部分の少なくとも一端にわたって延在し、前記医薬源および前記揮発性送達促進化合物源をシールする少なくとも1つの壊れやすいバリアと、
少なくとも1つの穿孔要素を収容し、その中に管状部分を受容するよう構成されるマウスピース部分とを含み、前記管状部分が前記マウスピース部分に挿入されるとき、前記少なくとも1つの穿孔要素が、前記少なくとも1つの壊れやすいバリアに穴を開けるよう配置される少なくとも1つの弾性部材を含むエアロゾル発生物品とを含む、エアロゾル発生システム。 - 前記発熱体が、前記エアロゾル発生装置に取り付けられた近位端および前記エアロゾル発生物品に挿入される自由遠位端を備える細長い発熱体であって、前記エアロゾル発生物品が、前記エアロゾル発生装置と係合するとき、前記少なくとも1つの弾性部材が、前記発熱体に弾性的に付勢されるよう配置される、請求項3に記載のエアロゾル発生システム。
- 前記発熱体が第1および第2の弾性部材の間に配置されるように、前記エアロゾル発生物品がエアロゾル発生装置と係合するとき、前記少なくとも1つの弾性部材が、前記発熱体に対してそれぞれ弾性的に付勢されるように構成される第1および第2の弾性部材を備える、請求項4に記載のエアロゾル発生システム。
- エアロゾル発生システムであって、
発熱体を含むエアロゾル発生装置と、
前記エアロゾル発生装置と係合するよう構成されるエアロゾル発生物品であって、
医薬源と、
揮発性送達促進化合物源と、
前記医薬源および前記揮発性送達促進化合物源をシールする少なくとも1つの壊れやすいバリアと、
前記エアロゾル発生物品の壁に備えられた少なくとも1つの穿孔要素とを含み、前記医薬源および前記揮発性送達促進化合物源が、前記少なくとも1つの穿孔要素に対して移動可能で、ユーザーによって起動されるとき、前記少なくとも1つの穿孔要素が、前記少なくとも1つの壊れやすいバリアに穴を開けるよう配置されるエアロゾル発生物品とを含む、エアロゾル発生システム。 - 前記エアロゾル発生物品が、前記医薬源および前記揮発性送達促進化合物源を収容する管状部分を備え、前記少なくとも1つの壊れやすいバリアが、前記管状部分の少なくとも一端にわたって延在する少なくとも1つの壊れやすいバリアを含む、請求項6に記載のエアロゾル発生システム。
- 前記少なくとも1つの壊れやすいバリアが、前記医薬源をシールする第1の壊れやすいバリアおよび前記揮発性送達促進化合物源をシールする第2の壊れやすいバリアを含み、前記少なくとも1つの穿孔要素が、前記医薬源に隣接する前記エアロゾル発生物品の壁に備えられる第1の穿孔要素および前記揮発性送達促進化合物源に隣接する前記エアロゾル発生物品の前記壁に備えられる第2の穿孔要素を含む、請求項6または7に記載のエアロゾル発生システム。
- 前記エアロゾル発生物品が、エアロゾル発生物品の内側に備えられた少なくとも1つの弾性部材を含み、前記医薬源および前記揮発性送達促進化合物源が、前記少なくとも1つの弾性部材上に備えられ、前記少なくとも1つの穿孔要素の方への前記少なくとも1つの弾性部材の動きにより、前記少なくとも1つの穿孔要素が前記少なくとも1つの壊れやすいバリアに穴を開けることを可能にするように前記少なくとも1つの弾性部材を配置する、請求項6〜8のいずれかに記載のエアロゾル発生システム。
- 前記少なくとも1つの穿孔要素が、前記エアロゾル発生物品の第1の壁に備えられ、前記医薬源および前記揮発性送達促進化合物源が、前記エアロゾル発生物品の第2の壁に備えられ、前記エアロゾル発生物品の前記第1および第2の壁が、前記第1の壁と第2の壁との間の相対運動により、前記少なくとも1つの穿孔要素が前記少なくとも1つの壊れやすいバリアに穴を開けることを可能にするように互いに対して移動可能である、請求項6〜8のいずれかに記載のエアロゾル発生システム。
- 前記エアロゾル発生装置および前記エアロゾル発生物品が、前記医薬源を摂氏50度〜150度の温度に加熱するよう構成されている、請求項1〜10のいずれかに記載のエアロゾル発生システム。
- 前記エアロゾル発生装置および前記エアロゾル発生物品が、前記揮発性送達促進化合物源を摂氏30度〜100度の間の温度に加熱するよう構成されている、請求項1〜11のいずれかに記載のエアロゾル発生システム。
- 前記医薬源がニコチンを含む、請求項1〜12のいずれかに記載のエアロゾル発生システム。
- 前記揮発性送達促進化合物源が酸を含む、請求項1〜13のいずれかに記載のエアロゾル発生システム。
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PCT/EP2016/056572 WO2016156212A1 (en) | 2015-03-27 | 2016-03-24 | Aerosol-generating system comprising integrated piercing element |
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CN114732167A (zh) | 2022-07-12 |
JP2018510626A (ja) | 2018-04-19 |
PL3273811T3 (pl) | 2020-06-01 |
CA2977592A1 (en) | 2016-10-06 |
US20210219614A1 (en) | 2021-07-22 |
WO2016156212A1 (en) | 2016-10-06 |
RU2695840C2 (ru) | 2019-07-29 |
MX2017012226A (es) | 2018-01-30 |
RU2017134369A3 (ja) | 2019-04-03 |
RU2017134369A (ru) | 2019-04-03 |
EP3273811A1 (en) | 2018-01-31 |
EP3273811B1 (en) | 2019-12-18 |
KR20170130392A (ko) | 2017-11-28 |
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US20180043113A1 (en) | 2018-02-15 |
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