JP6435053B2 - クレアチニン濃度測定装置の較正方法 - Google Patents
クレアチニン濃度測定装置の較正方法 Download PDFInfo
- Publication number
- JP6435053B2 JP6435053B2 JP2017532883A JP2017532883A JP6435053B2 JP 6435053 B2 JP6435053 B2 JP 6435053B2 JP 2017532883 A JP2017532883 A JP 2017532883A JP 2017532883 A JP2017532883 A JP 2017532883A JP 6435053 B2 JP6435053 B2 JP 6435053B2
- Authority
- JP
- Japan
- Prior art keywords
- temperature
- concentration
- calibration
- crn
- solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000000034 method Methods 0.000 title claims description 51
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 title claims description 41
- 229940109239 creatinine Drugs 0.000 title claims description 20
- 239000012482 calibration solution Substances 0.000 claims description 101
- 239000000243 solution Substances 0.000 claims description 49
- 238000005259 measurement Methods 0.000 claims description 43
- 239000000523 sample Substances 0.000 claims description 29
- 230000008859 change Effects 0.000 claims description 26
- CVSVTCORWBXHQV-UHFFFAOYSA-N creatine Chemical compound NC(=[NH2+])N(C)CC([O-])=O CVSVTCORWBXHQV-UHFFFAOYSA-N 0.000 claims description 18
- 230000035945 sensitivity Effects 0.000 claims description 17
- 238000003860 storage Methods 0.000 claims description 12
- 229960003624 creatine Drugs 0.000 claims description 9
- 239000006046 creatine Substances 0.000 claims description 9
- 238000009529 body temperature measurement Methods 0.000 claims description 6
- 101100096319 Drosophila melanogaster Spc25 gene Proteins 0.000 description 22
- 238000006243 chemical reaction Methods 0.000 description 21
- 230000006870 function Effects 0.000 description 10
- 238000004364 calculation method Methods 0.000 description 8
- 239000012528 membrane Substances 0.000 description 8
- 108090000790 Enzymes Proteins 0.000 description 7
- 102000004190 Enzymes Human genes 0.000 description 7
- 239000012491 analyte Substances 0.000 description 7
- 230000001419 dependent effect Effects 0.000 description 6
- 239000010410 layer Substances 0.000 description 6
- 238000004519 manufacturing process Methods 0.000 description 6
- 230000008569 process Effects 0.000 description 6
- 239000007864 aqueous solution Substances 0.000 description 4
- 239000000872 buffer Substances 0.000 description 4
- 239000013626 chemical specie Substances 0.000 description 4
- 238000007254 oxidation reaction Methods 0.000 description 4
- 230000004044 response Effects 0.000 description 4
- 230000002441 reversible effect Effects 0.000 description 4
- 108010077078 Creatinase Proteins 0.000 description 3
- 108090000604 Hydrolases Proteins 0.000 description 3
- 108010060059 Sarcosine Oxidase Proteins 0.000 description 3
- 102000008118 Sarcosine oxidase Human genes 0.000 description 3
- 239000003054 catalyst Substances 0.000 description 3
- 238000006297 dehydration reaction Methods 0.000 description 3
- 239000003792 electrolyte Substances 0.000 description 3
- 238000004128 high performance liquid chromatography Methods 0.000 description 3
- 230000007062 hydrolysis Effects 0.000 description 3
- 238000006460 hydrolysis reaction Methods 0.000 description 3
- 239000002609 medium Substances 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 238000006722 reduction reaction Methods 0.000 description 3
- 239000012086 standard solution Substances 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 101150040772 CALY gene Proteins 0.000 description 2
- ODINCKMPIJJUCX-UHFFFAOYSA-N Calcium oxide Chemical compound [Ca]=O ODINCKMPIJJUCX-UHFFFAOYSA-N 0.000 description 2
- 238000013459 approach Methods 0.000 description 2
- 239000012736 aqueous medium Substances 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 230000018044 dehydration Effects 0.000 description 2
- 238000009795 derivation Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 239000008151 electrolyte solution Substances 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 230000003647 oxidation Effects 0.000 description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
- 238000003908 quality control method Methods 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 229910021607 Silver chloride Inorganic materials 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000006911 enzymatic reaction Methods 0.000 description 1
- 230000014509 gene expression Effects 0.000 description 1
- 208000017169 kidney disease Diseases 0.000 description 1
- 239000002346 layers by function Substances 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000007430 reference method Methods 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- HKZLPVFGJNLROG-UHFFFAOYSA-M silver monochloride Chemical compound [Cl-].[Ag+] HKZLPVFGJNLROG-UHFFFAOYSA-M 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
- G01N27/3274—Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/001—Enzyme electrodes
- C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/70—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving creatine or creatinine
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/902—Oxidoreductases (1.)
- G01N2333/906—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7)
- G01N2333/9065—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7) acting on CH-NH groups of donors (1.5)
- G01N2333/90672—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7) acting on CH-NH groups of donors (1.5) with oxygen as acceptor (1.5.3) in general
- G01N2333/90677—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7) acting on CH-NH groups of donors (1.5) with oxygen as acceptor (1.5.3) in general with a definite EC number (1.5.3.-)
- G01N2333/90683—Sarcosine oxidase (1.5.3.1)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/978—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
- G01N2333/986—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides (3.5.2), e.g. beta-lactamase (penicillinase, 3.5.2.6), creatinine amidohydrolase (creatininase, EC 3.5.2.10), N-methylhydantoinase (3.5.2.6)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analyzing Materials Using Thermal Means (AREA)
Description
A→A++e−
X+e−→X−
H2O2→2H++O2+2e−
Claims (16)
- 1つ以上の較正溶液を使用した、クレアチニン濃度を測定するデバイスの較正方法であって、
前記1つ以上の較正溶液の、初期時間のクレアチン(Cr)及び/又はクレアチニン(Crn)濃度を受信することと、
前記測定デバイスの出力を受信すること、
終了時間において、温度モデルと、前記受信された初期時間の濃度と、を使用して、前記較正溶液中のCr及び/又はCrnの濃度を計算することであって、前記温度モデルが前記初期時間から前記終了時間までの前記較正溶液の温度の変化を示す、ことと、
前記測定デバイスの前記出力と、前記計算されたCr及び/又はCrn濃度との関係を決定することと、を含む方法。 - 前記測定デバイスは1つ以上の前記較正溶液中のクレアチンを測定するセンサを含む、請求項1に記載の方法。
- 前記測定デバイスは1つ以上の前記較正溶液中のクレアチニンを測定するセンサを含む、請求項1又は2に記載の方法。
- 前記測定デバイスは1つ以上の前記較正溶液中のクレアチン及びクレアチニンを測定するセンサを含む、請求項1〜3のいずれか一項に記載の方法。
- 前記測定デバイスは電流測定デバイスである、請求項1〜4のいずれか一項に記載の方法。
- 前記較正溶液の前記初期時間から前記終了時間までの温度変化の測定値を、温度プローブから受信することによって、前記温度モデルを決定することを更に含む、請求項1〜5のいずれか一項に記載の方法。
- 前記受信した測定値は記録された測定値である、請求項6に記載の方法。
- 前記温度モデルを前記決定することは、前記受信した前記温度変化の測定値を、第2の温度プローブで較正することを含む、請求項6又は7に記載の方法。
- 前記測定デバイスの出力と前記計算されたCr及び/又はCrn濃度との関係を決定することは、前記測定デバイスのセンサ感度を計算することを含む、請求項1〜8のいずれか一項に記載の方法。
- 前記終了時間の後に、温度測定値を受信することと、前記計算した前記測定デバイスの感度を、前記終了時間の後に受信した前記温度測定値を使用して更新することと、を更に含む、請求項9に記載の方法。
- 前記終了時間は前記初期時間から14日超経過後である、請求項1〜10のいずれか一項に記載の方法。
- 命令を含むコンピュータ可読記憶媒体であって、前記命令が、電子デバイスの1つ以上のプロセッサにより実行されたときに、前記電子デバイスを、請求項1〜11のいずれか一項で請求した方法に従って動作させる、コンピュータ可読記憶媒体。
- 電子デバイスであって、
1つ以上のプロセッサと、
1つ以上の前記プロセッサにより実行されたときに、前記電子デバイスを請求項1〜11のいずれか一項で請求した方法に従って動作させる命令を含むメモリと、を含む電子デバイス。 - 1つ以上の較正溶液を含み、請求項1〜11のいずれか一項に記載の方法の使用説明書又は請求項13に記載の電子デバイスを含む、パッケージであって、
当該パッケージが、Cr及び/又はCrnの濃度を測定するためのデバイスの較正のために使用される、
パッケージ。 - 前記初期時間並びに前記初期時間における前記1つ以上の較正溶液のCr及び/又はCrnの前記濃度の表示を更に含み、
前記表示が、書面で前記パッケージ上に記憶されるか、または、パッケージ自体に電子的に記憶されるものである、
請求項14に記載のパッケージ。 - 前記初期時間から前記終了時間までの前記クレアチニン溶液の前記温度を測定するための温度プローブと、前記測定温度を記録するためのメモリを更に含む、請求項14又は15に記載のパッケージ。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA201400737 | 2014-12-18 | ||
DKPA201400737 | 2014-12-18 | ||
PCT/EP2015/080131 WO2016097078A1 (en) | 2014-12-18 | 2015-12-17 | Method for calibrating a device for measuring the concentration of creatinine |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2018211046A Division JP6866337B2 (ja) | 2014-12-18 | 2018-11-09 | クレアチニン濃度測定装置の較正方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2018500563A JP2018500563A (ja) | 2018-01-11 |
JP6435053B2 true JP6435053B2 (ja) | 2018-12-05 |
Family
ID=54850194
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2017532883A Active JP6435053B2 (ja) | 2014-12-18 | 2015-12-17 | クレアチニン濃度測定装置の較正方法 |
JP2018211046A Active JP6866337B2 (ja) | 2014-12-18 | 2018-11-09 | クレアチニン濃度測定装置の較正方法 |
JP2021065083A Active JP7183331B2 (ja) | 2014-12-18 | 2021-04-07 | クレアチニン濃度測定装置の較正方法 |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2018211046A Active JP6866337B2 (ja) | 2014-12-18 | 2018-11-09 | クレアチニン濃度測定装置の較正方法 |
JP2021065083A Active JP7183331B2 (ja) | 2014-12-18 | 2021-04-07 | クレアチニン濃度測定装置の較正方法 |
Country Status (5)
Country | Link |
---|---|
US (2) | US20170363567A1 (ja) |
EP (1) | EP3234564A1 (ja) |
JP (3) | JP6435053B2 (ja) |
CN (2) | CN107110815B (ja) |
WO (1) | WO2016097078A1 (ja) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107003326B (zh) * | 2014-12-18 | 2019-10-22 | 雷迪奥米特医学公司 | 对用于测量肌酸酐浓度的设备进行校准的方法 |
KR102519408B1 (ko) * | 2019-04-05 | 2023-04-10 | 인스트루멘테이션 래보라토리 컴퍼니 | 다중 효소 바이오센서 및 실온에서의 다중 효소 바이오센서의 안정화 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5758895A (en) * | 1980-09-24 | 1982-04-08 | Hitachi Ltd | Analytical method of creatinine and apparatus |
WO1995022602A1 (en) | 1994-02-18 | 1995-08-24 | Genzyme Corporation | Isoenzyme calibrator/control products |
US6136607A (en) | 1995-11-02 | 2000-10-24 | Bayer Corporation | Multi-analyte reference solutions with stable pO2 in zero headspace containers |
JP3271741B2 (ja) * | 1996-06-04 | 2002-04-08 | 株式会社日立製作所 | 自動分析方法及び装置 |
US6241863B1 (en) * | 1998-04-27 | 2001-06-05 | Harold G. Monbouquette | Amperometric biosensors based on redox enzymes |
ATE258028T1 (de) * | 1998-05-13 | 2004-02-15 | Cygnus Therapeutic Systems | Signalverarbeitung zur messung von physiologischen analyten |
AT409040B (de) * | 2000-08-11 | 2002-05-27 | Roche Diagnostics Gmbh | Creatininsensor-kalibration |
ES2633729T3 (es) * | 2001-08-22 | 2017-09-25 | Instrumentation Laboratory Company | Método para calibrar sensores electroquímicos |
JP4431147B2 (ja) | 2003-11-28 | 2010-03-10 | ラジオメーター・メディカル・アー・ペー・エス | 参照溶液 |
US7275863B1 (en) * | 2003-12-04 | 2007-10-02 | Time Temperature Integration, Inc. | Threshold calorimeter/shelf life monitor |
ATE450620T1 (de) * | 2004-10-05 | 2009-12-15 | Siemens Healthcare Diagnostics | Stabiler kreatinin-biosensor mit drei enzymen |
JP5693960B2 (ja) * | 2007-09-13 | 2015-04-01 | アボット ポイント オブ ケア インコーポレイテッド | ポイント・オブ・ケア検査のための改善された品質保証システムおよび方法 |
WO2011037702A1 (en) | 2009-09-24 | 2011-03-31 | Fresenius Medical Care Holdings, Inc. | Amperometric creatinine biosensor with immobilized enzyme-polymer composition and systems using same, and methods |
WO2013003711A1 (en) * | 2011-06-30 | 2013-01-03 | Abbott Point Of Care Inc. | Methods and devices for sensing device signal correction |
EP2726860A1 (en) * | 2011-06-30 | 2014-05-07 | Abbott Point of Care Inc. | Methods and devices for determining sensing device usability |
WO2013003705A1 (en) * | 2011-06-30 | 2013-01-03 | Abbott Point Of Care Inc. | Methods and devices for determining sensing device usability |
GB2512842A (en) * | 2013-04-08 | 2014-10-15 | Sphere Medical Ltd | Sensor calibration method and apparatus |
AU2014262833B2 (en) | 2013-05-06 | 2019-10-31 | Bio-Rad Laboratories, Inc. | Stabilization of labile analytes in reference materials |
CN107003326B (zh) * | 2014-12-18 | 2019-10-22 | 雷迪奥米特医学公司 | 对用于测量肌酸酐浓度的设备进行校准的方法 |
-
2015
- 2015-12-17 CN CN201580069428.4A patent/CN107110815B/zh active Active
- 2015-12-17 WO PCT/EP2015/080131 patent/WO2016097078A1/en active Application Filing
- 2015-12-17 JP JP2017532883A patent/JP6435053B2/ja active Active
- 2015-12-17 EP EP15810663.3A patent/EP3234564A1/en active Pending
- 2015-12-17 CN CN202111025880.4A patent/CN113866236A/zh active Pending
- 2015-12-17 US US15/536,309 patent/US20170363567A1/en not_active Abandoned
-
2018
- 2018-11-09 JP JP2018211046A patent/JP6866337B2/ja active Active
-
2021
- 2021-04-07 JP JP2021065083A patent/JP7183331B2/ja active Active
- 2021-10-25 US US17/509,485 patent/US11965854B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
CN113866236A (zh) | 2021-12-31 |
WO2016097078A1 (en) | 2016-06-23 |
US20170363567A1 (en) | 2017-12-21 |
EP3234564A1 (en) | 2017-10-25 |
CN107110815B (zh) | 2021-09-21 |
CN107110815A (zh) | 2017-08-29 |
US11965854B2 (en) | 2024-04-23 |
JP7183331B2 (ja) | 2022-12-05 |
JP2019053079A (ja) | 2019-04-04 |
JP2021107823A (ja) | 2021-07-29 |
JP6866337B2 (ja) | 2021-04-28 |
US20220113274A1 (en) | 2022-04-14 |
JP2018500563A (ja) | 2018-01-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP6510046B2 (ja) | 新規較正方法 | |
US11965854B2 (en) | Method for calibrating a device for measuring the concentration of creatinine | |
Spitzer et al. | The history and development of a rigorous metrological basis for pH measurements | |
Leito et al. | Estimation of uncertainty in routine pH measurement | |
EP2715369B1 (en) | Optical glucose biosensor calibration using different temperature calibration solutions | |
CN111537487B (zh) | 一种光学氧传感器的温度补偿方法及装置 | |
JP2017531785A (ja) | 拡散を測定するための方法 | |
US20240230578A1 (en) | Method for calibrating a device for measuring the concentration of creatinine | |
JP6557740B2 (ja) | カルシウム阻害に関するcreaセンサの補正方法 | |
CN107110813A (zh) | 对内源性调节剂进行校正的安培型肌酸酐传感器的校准概念 | |
Jalukse et al. | Estimation of uncertainty in electrochemical amperometric measurement of dissolved oxygen concentration | |
KR101079790B1 (ko) | 카이네틱 변화 정보를 이용한 측정목표물질의 특징값 추정방법 및 장치 | |
Doinikov et al. | The pH scale for aqueous solutions as an international standard | |
JP2005265686A (ja) | データ校正方法および校正データの提供方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20180416 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20180516 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20180710 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20180926 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20181012 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20181109 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 6435053 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
R157 | Certificate of patent or utility model (correction) |
Free format text: JAPANESE INTERMEDIATE CODE: R157 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |