JP6402155B2 - 大きいボアの核及び磁気共鳴イメージング又は大きいボアのct及び磁気共鳴イメージングを用いた放射線治療プランニング及びフォローアップシステム - Google Patents
大きいボアの核及び磁気共鳴イメージング又は大きいボアのct及び磁気共鳴イメージングを用いた放射線治療プランニング及びフォローアップシステム Download PDFInfo
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Description
Claims (15)
- MR長手方向軸に沿って被検体を受け入れるMR撮像領域を画成する第1ボアを有する磁気共鳴(MR)スキャナであり、前記第1ボアは少なくとも70cmの直径を有する、MRスキャナ;
第2長手方向軸に沿って前記被検体を受け入れる第2撮像領域を画成する第2ボアを有する第2スキャナであり、前記第2長手方向軸は前記MR長手方向軸と揃えられ、前記第2ボアは少なくとも70cmの直径を有する、第2スキャナ;
前記MR撮像領域及び前記第2撮像領域を通って直線状に移動し、前記被検体を順次に前記MR撮像領域内及び前記第2撮像領域内に位置付ける放射線治療カウチ;及び
1つ以上のプロセッサであり、
前記MR撮像領域及び前記第2撮像領域の一方内に位置付けられた前記被検体に関して、標的ボリュームのMR画像描写又は第2画像描写を収集し、対応する撮像領域に対して前記標的ボリュームを位置特定し、
位置特定された前記標的ボリュームを前記放射線治療カウチに対してレジストレーションし、前記放射線治療カウチに対する前記被検体の期待される座標位置を決定し、
前記MR撮像領域及び前記第2撮像領域の前記一方から他方へと位置変更された前記被検体に関して、前記他方に対応する前記MRスキャナ及び前記第2スキャナのうちの1つを用いて、前記標的ボリュームのMR画像描写又は第2画像描写を収集し、
前記MR画像描写及び前記第2画像描写を結合画像描写へと結合し、且つ
収集された前記MR画像描写及び前記第2画像描写に従って放射線治療計画を生成あるいは更新する、
ように構成された1つ以上のプロセッサ;
を有する放射線治療プランニング及びフォローアップシステム。 - 前記MR撮像領域内でのデータ収集から生成される画像描写と、前記第2撮像領域内でのデータ収集から生成される画像描写とを、合成画像描写へと結合する融合プロセッサ;及び
前記合成画像描写に従って放射線治療計画を生成するプランニングプロセッサ;
を含む請求項1に記載の放射線治療プランニング及びフォローアップシステム。 - 前記放射線治療カウチは:
選択された固定位置に前記被検体を固定する多様な拘束装置を受け入れる少なくとも1つの取付け構造;及び
当該放射線治療カウチの表面に配設され、あるいは当該放射線治療カウチの内部に組み込まれた、複数のレジストレーションマーク;
を含む、請求項1又は2に記載の放射線治療プランニング及びフォローアップシステム。 - 前記放射線治療カウチの位置を前記被検体に対してレジストレーションする患者レジストレーションシステム;
前記MR撮像領域及び前記第2撮像領域のアイソセンタに対して正確な関係を有する少なくとも1つのレーザであり、前記被検体の上、前記被検体に取り付けられた固定装置の上、及び/又は前記放射線治療カウチの上に配置された複数のレジストレーションマークの各々の位置を表す信号を生成する少なくとも1つのレーザ;及び
該生成された信号に従って各レジストレーションマークの3次元座標位置を決定するレジストレーションプロセッサ;
を含む請求項1乃至3の何れか一項に記載の放射線治療プランニング及びフォローアップシステム。 - 前記MRスキャナ及び前記第2スキャナの双方によって検出可能なレジストレーションマークと、前記MR撮像領域及び前記第2撮像領域のスキャンから前記レジストレーションマークの座標位置を決定するレジストレーションプロセッサと、
を含む請求項1乃至4の何れか一項に記載の放射線治療プランニング及びフォローアップシステム。 - 前記レジストレーションプロセッサは、各レジストレーションマークの実際の座標位置と期待される座標位置とに基づくフィードバック信号を生成し、且つ:
生成した前記フィードバック信号をグラフィカルユーザインタフェース上に表示する;
前記放射線治療カウチの位置、及び/又は画像収集するスライス若しくはスラブの位置を調整するよう、MRスキャンコントローラ及び核スキャンコントローラのうちの少なくとも一方に命令する;及び
核画像描写とMR画像描写とを結合する融合プロセッサに前記フィードバック信号を提供する;
のうちの少なくとも1つを行う、請求項4又は5に記載の放射線治療プランニング及びフォローアップシステム。 - 前記第2スキャナは核スキャナを含み、該核スキャナは:
前記第2撮像領域に隣接配置されたリング状の光検出器であり、シンチレータ層に光的に結合されて、前記第2撮像領域内で放射された放射線に応答して核撮像データを生成する光検出器;及び
前記シンチレータ層と前記第2撮像領域との間に配置された無線周波数シールドであり、必要に応じて該核スキャナの全体を囲む無線周波数シールド;
を含む、請求項1乃至6の何れか一項に記載の放射線治療プランニング及びフォローアップシステム。 - 前記核スキャナは更に:
前記MR画像描写の収集中に、前記光検出器の電源を落とす又は前記光検出器の動作電圧を低下させる回路;及び
前記光検出器に隣接した加熱素子であり、前記光検出器及びその関連回路の温度を、前記MR画像描写の収集後に定格動作温度まで上昇させ、あるいは前記MR画像描写の収集中に最低動作温度以上に維持する、加熱素子
を含む、請求項7に記載の放射線治療プランニング及びフォローアップシステム。 - 当該放射線治療プランニング及びフォローアップシステムは、1つの位置から別の1つの位置へと輸送されることが可能な移動式プラットフォーム上に配置される、請求項1乃至8の何れか一項に記載の放射線治療プランニング及びフォローアップシステム。
- 1つ以上のプロセッサによって実行される、放射線治療計画を生成あるいは更新するためのシステムの作動方法であって:
MRスキャナのMR撮像領域及び第2スキャナの第2撮像領域の一方内に位置付けられた、放射線治療カウチによって支持された被検体に関して、標的ボリュームのMR画像描写又は第2画像描写を収集し、対応する撮像領域に対して前記標的ボリュームを位置特定するステップ;
位置特定された前記標的ボリュームを前記放射線治療カウチに対してレジストレーションし、前記放射線治療カウチに対する前記被検体の期待される座標位置を決定するステップ;
前記MR撮像領域及び前記第2撮像領域の前記一方から、前記一方と共通の長手方向軸を共有する他方へと、直線的に位置変更された前記被検体に関して、前記他方に対応する前記MRスキャナ及び前記第2スキャナのうちの1つを用いて、前記標的ボリュームのMR画像描写又は第2画像描写を収集するステップ;
前記MR画像描写及び前記第2画像描写を結合画像描写へと結合するステップ;及び
収集された前記MR画像描写及び前記第2画像描写に従って放射線治療計画を生成あるいは更新するステップ;
を有し、
前記MR撮像領域を画成する第1ボア及び前記第2撮像領域を画成する第2ボアは各々、少なくとも70cmの直径を有する、
方法。 - 前記MR画像描写を収集するのに先立って、前記第2スキャナを休止モードに置き、且つ必要に応じて、前記第2スキャナ及び前記MRスキャナが互いに隣接しないように、前記第2スキャナをガントリートラックに沿って前記MRスキャナから遠ざかる方に移動させるステップ;及び
前記MR画像描写を収集した後に、前記第2スキャナをアクティブモードに置き、且つ必要に応じて、前記第2スキャナ及び前記MRスキャナが互いに隣接するように、前記第2スキャナをガントリートラックに沿って前記MRスキャナの方に移動させるステップ;
を更に含む請求項10に記載の方法。 - 前記第2画像描写を収集するのに先立って、前記MRスキャナを休止モードに置き、且つ必要に応じて、前記第2スキャナ及び前記MRスキャナが互いに隣接するように、前記第2スキャナをガントリートラックに沿って前記MRスキャナの方に移動させるステップ;及び
前記第2画像描写を収集した後に、前記MRスキャナをアクティブモードに置き、且つ必要に応じて、前記第2スキャナ及び前記MRスキャナが互いに隣接しないように、前記第2スキャナをガントリートラックに沿って前記MRスキャナから遠ざかる方に移動させるステップ;
を更に含む請求項10又は11に記載の方法。 - 前記第2スキャナは核スキャナを含み、当該方法は更に:
前記核スキャナが休止モードにある間、前記核スキャナの光検出器の最低動作温度を維持するステップ、
を含む、請求項11又は12に記載の方法。 - 前記核スキャナをアクティブモードに置いている間、前記核スキャナの光検出器を定格動作温度まで加熱するステップ、
を更に含む請求項13に記載の方法。 - 前記核スキャナの光検出器及び電子装置を、前記MRスキャナのRF及び静止磁場干渉から遮蔽するステップ、
を更に含む請求項13又は14に記載の方法。
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